Thursday, April 9, 2020





                                       The Cephalic Investigation - 
                            Race Eugenics & Dysgenics 

           Skull Evolution & The History of the Lineage of Man


                            
                                        Website: MonsantoInvestigation.com

                                             Edited by Michael James Ross

                                            

 
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 The following Article will discuss the history and evolution with skulls of primates, animals
and humans. We will examine the medical and health problems found in skull deformations with humans and animals. This book will detail the evolution and de-evolution of different subraces and subspecies of primates and animals, including the health problems of certain brachycephalic species of animals and humans.



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Craniometry

https://en.wikipedia.org/wiki/Craniometry

Craniometry is measurement of the cranium (the main part of the skull), usually the human cranium. It is a subset of cephalometry, measurement of the head, which in humans is a subset of anthropometry, measurement of the human body. It is distinct from phrenology, the pseudoscience that tried to link personality and character to head shape, and physiognomy, which tried the same for facial features. However, these fields have all claimed the ability to predict traits or intelligence.

They were once intensively practised in anthropology, in particular in physical anthropology in the 19th and the first part of the 20th century. Theories attempting to scientifically justify the segregation of society based on race became popular at this time, one of their prominent figures being Georges Vacher de Lapouge (1854–1936), who divided humanity into various, hierarchized, different "races", spanning from the "Aryan white race, dolichocephalic" (from the Ancient Greek kephalĂȘ, head, and dolikhos, long and thin), to the "brachycephalic" (short and broad-headed) race. On the other hand, craniometry was also used as evidence against the existence of a "Nordic race" and also by Franz Boas who used the cephalic index to show the influence of environmental factors. Charles Darwin used craniometry and the study of skeletons to demonstrate his theory of evolution first expressed in On the Origin of Species (1859).

More direct measurements involve examinations of brains from corpses, or more recently, imaging techniques such as MRI, which can be used on living persons. Such measurements are used in research on neuroscience and intelligence.




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                                                        (Brown people are a Subspecies)
                                                     























































                                                                   (Asian Subspecies)










                                               (Reconstruction of a H. floresiensis woman)










                                                                 (Brown Subspecies)









                     











                                                {Black Subspecies (Bloodshot red eyes)}








































































































 

 

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                                                                 (Epicanthal folds)



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SOME RACIAL PECULIARITIES OF THE NEGRO BRAIN

https://deepblue.lib.umich.edu/bitstream/handle/2027.42/49594/1000050402_ftp.pdf





Outlines  with brain axis, and these points located on the brain of an adult male Negro (No. 1528) and of an adult male Caucasian (No. 1690) are seen in figures la to 3b, there being semicircles drawn around each hemisphere to facilitate comparison.    These  two brains are selected be- cause they are nearly  alike in many respects, but still show the racial characteristics. They are taken from young adult males of about the same age, the brains being of about the same size and weight. From these out- lines it is observed that the Caucasian brain conforms  more nearly to a circle in its contour in the different planes than does that of the Negro, which is squared at the ends, and flatter on the sides and above, especially along the frontal lobes, thus exhibiting a  distinct box-shaped  appearance. This shape of the Negro brain is manifested in  the mesial outline by the  abrupt rise of the contour from the axis at its posterior end, by the nearly straight line over the  anterior association  center, by the nearly vertical line along the anterior aspect of the  frontal lobe, and by the horizontal line along the inferior border of this lobe; it is manifested in the outline from above by the square front and sides of the outline; and in the outline with the brain rotated  laterally  45", by the more abrupt rise posteriorly, and the depression or apparent  flattening over the an- terior association  center, along with the relative bulging of the posterior association  center. These differences are seen more plainly in Figure 4 (brains No. 1473 and 1538) which represents the 45" outlines of a fairly typical adult male  Caucasian brain, and of a  fairly typical adult male Negro brain of about the same weight and length. It is the straight line seen  over the anterior association center in this figure  on  which  especial emphasis is laid as  a distinctive characteristic of the Negro brain. Look- ing at the brain directly from above or from the side one does not so readily notice any apparent flattening, but on rotating the brain on its axis slightly to one side  a  glance will often bring it out distinctly; or a careful examination, revolving the brain from 10" to 60" from its normal position and looking at it from above, wiIl almost invariably disclose this peculiarity. In some brains it is well marked, in others only slightly so. It usually appears most marked when either hemisphere is rotated through an angle of 30" laterally from its normal position and viewed from above. Viewed from the side the Negro brain appears to be pressed  back, while the Caucasian appears to be pushed forward, the result being that the frontal lobe of the Negro brain appears considerably smaller than that of the Caucasian. This difference is greater than is apparent in the outlines, because the gyrus rectus in the Negro brain is low, while the superior orbital plate passes well up into the frontal lobe outside of this, materially diminishing the size of this lobe, the gyrus  frontalis superior also projecting  upward in Negro  brains more than in the Caucasian. This is shown in Figures 5 to 7, brain No. 1681, from a  typical adult male  Negro. The drawings are made from sawed sections of the frozen head, showing the brain in situ, no distortion of the brain being apparent. In this there may be observed the extremely small frontal lobes; the pro- jection downward of the gyrus rectus; the deep impression of the superior orbital plates; the straight lines along the sides anteriorly, showing the lateral surfaces of the  brain to be at an angle of 45O from the vertical plane; the upward  projection of the gyrus frontalis  superior; the bos- like  appearance of each outline; and  the great bulging in the parietal region. The female  Negro brain may  differ.somewhat from that of the male, but in general the same peculiarities are noticeable in each. Fig- ures 8" to 10b exhibit a characteristic adult female  Negro brain and a small adult female  Caucasian brain for comparison, the two being selected because they are so nearly alike, yet the racial differences are noticeable. The frontal lobes of the female Negro brain are long and slender,  while the parietal region is full and bulging. The peculiaries noted in the other  outlines may be seen in these also. Examination of about fifty Negro skulls, and hundreds of Negro  heads has convinced  me of a  noticeable characteristic: the appearance to be obtained by a  view from behind at an angle of about 30" above the hori- zontal  looking directly  forward. The outline of the head or skull seen in this way is pointed  anteriorly and broad and flattened posteriorly. This may be  seen in the Negro brains under the same conditions. Here we see the small frontal lobes, the large parietal region and the straight, flat sides over the anterior association  centers. That this is not only ap- parent, but real,  may be determined by measurements of the radii from the brain center to  the outlines of the plane  passing through the brain axis at an angle of 45" above the horizontal  plane of each  hemisphere. Such measurements are found in Table 11, which gives the dimensions of this plane in each non-distorted brain. Radii are projected from the brain center for each 10" angle, and perpendiculars are dropped from the brain axis for each centimeter on the axis from either  end of the brain, and these radii and perpendiculars are measured from their origin out to  the surface of the brain.



Topinard corroborates these statements, aind concludes that  the Negro has the cerebral cranium less  developed than the white, but its posterior portion is more developed than the anterior. It falls within the occipital races of Gratiolet 25 " and the Caucasian in his frontal races. Barnard Davis l3 l4 demonstrated  practically the same in relation to the radii from the external auditory meatus to the three regions of the skull, frontal, parietal and occipital. The white and the black  races arc evidently opposites in cardinal points. The one is subjective, the other objective; the one frontal, the other occipital or parietal; the one a  great reasoner, the other emotional ; the one domineering, but having  great self-control, the other meek and submissive, but violent and lacking self- control, especially  when the passions are aroused, or any sudden  danger appears; the one  a  greyhound, the other a  bulldog. Spitzka " emphasizes the differences of the two parts of the brain, an- terior and posterior, in comparing the brains of Prof. Joseph Leidy, Ma]. J. W. Powell and Prof. Cope, by contrasting the characteristics of these eminent men, and in so doing corroborates  Flechsig's. work and lends plausibility to the generalizations given above. Wagner R8727s gives some interesting figures in relation to the relative size of the various lobes in man and  the ourang-outang which may be appropriately  presented here.



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Racial Variations in Different Skulls

2014

https://www.jpsr.pharmainfo.in/Documents/Volumes/Vol6Issue11/jpsr06111407.pdf


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Race, head size, and intelligence

https://philipperushton.net/wp-content/uploads/2015/02/iq-race-brain-size-rushton-kamin-south-african-j-of-psychology-9-1998.pdf


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Skulls from ancient North Americans hint at multiple migration waves

January 29, 2020

https://www.livescience.com/skulls-from-first-north-americans-diverse.html


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 Mysterious ‘ghost’ populations had multiple trysts with human ancestors

Feb. 20, 2020

https://www.sciencemag.org/news/2020/02/mysterious-ghost-populations-had-multiple-trysts-human-ancestors


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 14 Different Types of Human Species | Explained

Apr 21, 2020

#13: Homo Sapiens Idaltu (Subspecies)

https://www.youtube.com/watch?v=1sC1gxFvCqQ







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 The Lost Ancient Humans of Antarctica

Feb 25, 2020

https://www.youtube.com/watch?v=iBF0hP2_nGw


{The reason why some Orientals have bigger heads and need less oxygen in Mountains is
because Orientals were part Denisovan. Orientals and Blacks were part animal and we are
calling for strict population control on their numbers. We must regulate these Orientals, Indians, Mexicans and black subspecies trying to overpopulate and then breed with white humans. If anything we should eliminate most of these subspecies in order for the white race to survive. Orientals, East Indians, American Indians, Mexicans and brown South Americans were all part Denisovan, this is why many brown skinned people are classified as a subspecies of human}.


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How breeding with an ancient human species gave Tibetans their head for heights

July 4, 2014

https://theconversation.com/how-breeding-with-an-ancient-human-species-gave-tibetans-their-head-for-heights-28818

A new study of the DNA of Tibetans has looked at the gene underlying their ability to live in the low-oxygen conditions at high altitudes. It found that this gene has come from an unexpected source – the mysterious group of ancient humans called the Denisovans. This work, a collaboration between Chinese, Danish and American scientists, has been published in the journal Nature.


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 Scientists Find The First-Ever Animal That Doesn't Need Oxygen to Survive

25 FEB 2020







https://www.sciencealert.com/this-is-the-first-known-animal-that-doesn-t-need-oxygen-to-survive



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Two pulses of Denisovans contributed to East Asian ancestry

March 16, 2018

Two distinct interbreeding events with Denisovans, a sister group to Neanderthals, contributed to the ancestry of modern East Asians, according to a genetic data analysis.

https://newsroom.uw.edu/news/two-pulses-denisovans-contributed-east-asian-ancestry



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 Why do Asians have bigger brains than Europeans or Africans?

2017

Chinese scientists discover natural selection played a role

https://www.scmp.com/news/china/article/2054126/why-do-asians-have-bigger-brains-europeans-or-africans



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How Your Nose Got Its Shape

Jul 31, 2016

Climate variation has sculpted our schnozzes since the earliest humans evolved, but environmental pressures can’t explain everything.

https://www.the-scientist.com/notebook/how-your-nose-got-its-shape-33101



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Denisovan Jawbone Discovered in a Cave in Tibet

https://www.nytimes.com/2019/05/01/science/denisovans-tibet-jawbone-dna.html



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Ancient gene flow from early modern humans into Eastern Neanderthals.

2016

 Abstract

It has been shown that Neanderthals contributed genetically to modern humans outside Africa 47,000-65,000 years ago. Here we analyse the genomes of a Neanderthal and a Denisovan from the Altai Mountains in Siberia together with the sequences of chromosome 21 of two Neanderthals from Spain and Croatia. We find that a population that diverged early from other modern humans in Africa contributed genetically to the ancestors of Neanderthals from the Altai Mountains roughly 100,000 years ago. By contrast, we do not detect such a genetic contribution in the Denisovan or the two European Neanderthals. We conclude that in addition to later interbreeding events, the ancestors of Neanderthals from the Altai Mountains and early modern humans met and interbred, possibly in the Near East, many thousands of years earlier than previously thought.

http://europepmc.org/article/PMC/4933530



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Measures of body composition in blacks and whites: a comparative review

https://academic.oup.com/ajcn/article/71/6/1392/4729362



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Are Negros Closer to Apes Than to Humans?

Are these facts in the museum:

The negro skull, in addition to having a smaller brain volume and thicker cranial bones than that of the White, is prognathous ; i.e., the lower face projects forward in the manner of an animal's muzzle. The negro jaw is substantially longer, relative to its width, than the White jaw. A feature of the negro lower jaw is its retention of a vestige of the "simian shelf," a bony region immediately behind the incisors. The simian shelf is a distinguishing characteristic of apes, and it is absent in Whites.

They emit a peculiar offensive body odor similar to apes.

Just as their black skin protected them from the intense African sun, they are inherently lazy in order to prevent over exertion in that intense sun.

The arms and legs of the negro are relatively longer than the European. The humerus is shorter and the forearm longer thereby approximating the ape form.

The eye often has a yellowish scierotic coat over it like that of a gorilla.

The negro has a shorter trunk; the cross-section of the chest is more circular than Whites. Similar to an ape.

The pelvis is narrower and longer as it is in an ape.

The negro has a larger and shorter neck akin to that of apes.

The ears are roundish, rather small, standing somewhat high and detached thus approaching the ape form.

The jaw is larger and stronger and protrudes outward which, along with lower retreating forehead, gives a facial angle of 68 to 70 degrees, like an ape, as opposed to a facial angle of 80 to 82 degrees for Europeans.

The three curvatures of the spine are less pronounced in the negro than in the white and thus more characteristic of an ape.

The two bones proper of the nose are occasionally united, as in apes.

Taxonomists and geneticists believe that negros should be classified as different species. In fact, Darwin declared in The Descent of Man that the negros are so distinct that similar differences found in any other animal would warrant their classification as a different species.

References:
Coon, Carleton S. The Origin of Races, 1962, Alfred A. Knopf
Howells, William. Mankind So Far, Doubleday, Garden City, NY
Weisman, Charles A. The Origins of Race and Civilization, 1990

https://www.ferris.edu/HTMLS/news/jimcrow/letters/2012/apes.htm


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 These Are The Strongest Animals Built By Evolution

Updated on February 13, 2020

https://www.science101.com/strongest-animals-built-by-evolution/


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Effects of Vitamin C Deficiency on Body Shape and Skull Osteology in Geophagus brasiliensis: Implications for Interpretations of Morphological Plasticity


May 3, 1993

https://www.jstor.org/stable/1447135?seq=1


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Are humans Gnathostomates?


https://biology.stackexchange.com/questions/70874/are-humans-gnathostomates


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TFClass: a classification of human transcription factors and their rodent orthologs

2015

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383905/



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Diversity of human and mouse homeobox gene expression in development and adult tissues.

02 Nov 2016

http://europepmc.org/article/PMC/5094009



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How Chewing Gave Humans Flat Faces, Little Teeth and Wimpy Jaws

June 10, 2016

https://www.atlasobscura.com/articles/how-chewing-gave-humans-flat-faces-little-teeth-and-wimpy-jaws



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Move over, DNA: ancient proteins are starting to reveal humanity’s history

11 July 2019

Proteins dating back more than one million years have been extracted from some fossils, and could help to answer some difficult questions about archaic humans.


https://www.nature.com/articles/d41586-019-01986-x



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Homo floresiensis: Making Sense of the Small-Bodied Hominin Fossils from Flores

Are the bones of several tiny individuals from the island of Flores the newest addition to our family tree, or are they the remains of diseased humans only masquerading as an extinct species?

https://www.nature.com/scitable/knowledge/library/homo-floresiensis-making-sense-of-the-small-91387735/



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The new skull, MRD, belongs to the species Australopithecus anamensis.


 August 29, 2019

https://www.thehindu.com/sci-tech/science/skull-discovered-in-ethiopia-yields-new-clues-on-how-humans-evolved/article29283628.ece



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Ancient skull discovery yields new clues on human evolution

29/08/2019

Ardi (for Ardipithecus ramidus, another species of hominid) was found in Ethiopia in 1994 and is believed to be around 4.5 million years old.

And Lucy, the famous Australopithecus afarensis, was discovered in Ethiopia in 1974 and is 3.2 million years old.

Australopithecus afarensis is one of the longest-lived and most studied early human species.

The new skull, MRD, belongs to the species Australopithecus anamensis.

Discovered in February 2016 at the site of Woranso-Mille, just 55 kilometres (34 miles) from where Lucy was found in the Afar region of northeastern Ethiopia, MRD offers "the first glimpse of the face of Lucy's ancestor," according to a statement announcing the finding.

Other lesser-known Australopithecus fossils date back at least 3.9 million years, but they featured only jaws and teeth. Without the skull, scientists' understanding of the evolution of these extinct hominids has remained limited.

https://www.france24.com/en/20190829-ancient-skull-discovery-yields-new-clues-human-evolution



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Richard Smith: How humans might divide into a superclass and a useless class

September 7, 2016

https://blogs.bmj.com/bmj/2016/09/07/richard-smith-how-humans-might-divide-into-a-superclass-and-a-useless-class/



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Superclass


https://www.thefreedictionary.com/superclass


Superclass: Definition - A taxonomic category of related organisms ranking below a phylum or its subdivisions and above a class.



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Superclasses of human TF DNA-binding domains.

Feb 2013

https://www.researchgate.net/figure/Superclasses-of-human-TF-DNA-binding-domains-For-each-superclass-the-structure-of-one_fig1_234578305


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The brain is the final frontier of our privacy, and AI is about to breach it

November 19, 2019

https://qz.com/1750852/what-ai-chips-do-to-peoples-brains/


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Human taxonomy

Overview of speciation and hybridization within the genus Homo over the last two million years (vertical axis). The rapid "Out of Africa" expansion of H. sapiens is indicated at the top of the diagram, with admixture indicated with Neanderthals, Denisovans, and unspecified archaic African hominins.

https://en.wikipedia.org/wiki/Human_taxonomy



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 Oldest ever human genetic evidence clarifies dispute over our ancestors

April 2020


https://www.sciencedaily.com/releases/2020/04/200401111657.htm

Summary:
    Genetic information from an 800,000-year-old human fossil has been retrieved for the first time. The results shed light on one of the branching points in the human family tree, reaching much further back in time than previously possible.

Genetic information from an 800,000-year-old human fossil has been retrieved for the first time. The results from the University of Copenhagen shed light on one of the branching points in the human family tree, reaching much further back in time than previously possible.

An important advancement in human evolution studies has been achieved after scientists retrieved the oldest human genetic data set from an 800,000-year-old tooth belonging to the hominin species Homo antecessor.

The findings by scientists from the University of Copenhagen (Denmark), in collaboration with colleagues from the CENIEH (National Research Center on Human Evolution) in Burgos, Spain, and other institutions, are published April 1st in Nature.

"Ancient protein analysis provides evidence for a close relationship between Homo antecessor, us (Homo sapiens), Neanderthals, and Denisovans. Our results support the idea that Homo antecessor was a sister group to the group containing Homo sapiens, Neanderthals, and Denisovans," says Frido Welker, Postdoctoral Research Fellow at the Globe Institute, University of Copenhagen, and first author on the paper.



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Homo antecessor: Common Ancestor of Humans and Neanderthals?

 November 26, 2012

A hominid that lived in Europe more than a million years ago might have given rise to Neanderthals and Homo sapiens, some anthropologists say

https://www.smithsonianmag.com/science-nature/homo-antecessor-common-ancestor-of-humans-and-neanderthals-143357767/


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'Hobbit' species did not evolve from ancestor of modern humans, research finds


April 2017

Bone study shows there is no evidence the 1.1-metre tall Homo floresiensis had any links with the much larger Homo erectus


https://www.theguardian.com/science/2017/apr/21/hobbit-species-did-not-evolve-from-ancestor-of-modern-humans-research-finds

 


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Mystery human hobbit ancestor may have been first out of Africa

21 April 2017

https://www.theguardian.com/technology/2020/apr/02/zoom-technology-security-coronavirus-video-conferencing



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Homo Floresiensis: Facts About the 'Hobbit'

March 30, 2016

https://www.livescience.com/29100-homo-floresiensis-hobbit-facts.html

Homo floresiensis, dubbed "the Hobbit," was an ancient hominin that lived until at least 17,000 years ago.  

Scientists discovered the first H. floresiensis fossil, along with stone tools and animal remains, in 2003 in the Liang Bua (LB) cave on the remote Indonesian island of Flores, according to a 2004 Nature paper. This first specimen — a 3.5-foot-tall (1.06 meter), 30-year-old adult female called LB1 — comprised a nearly complete skull and an associated skeleton, which includes several limb bones, hand and foot bones and a partial pelvis, according to the journal Nature.

"Its associated skeleton is one of the things that makes this specimen quite exciting," Mark Collard, a biological anthropologist at Simon Fraser University in Burnaby, British Columbia, told Live Science "We don't have very many associated skeletons of hominins outside of Neanderthals."

LB1's tiny build earned the species the nickname of "the Hobbit," after the tiny folk in J.R.R. Tolkien's book of the same name.

In addition to LB1, archaeologists later discovered jaw and skeletal remains of at least eight other diminutive individuals, according to a 2009 article in the Journal of Human Evolution.  The small stature of these specimens suggests LB1 wasn't an anomaly.

Initial dating of the hobbit remains gave the species an age range of 74,000 to 17,000 years ago. However, dating of the associated tools and sediment deposits where the remains were discovered suggests H. floresiensis may have lived from as early as 95,000 years ago until about 12,000 years ago, according to a 2005 paper in Nature.

Just how H. floresiensis fits into the family tree of hominins — which includes those species that evolved after the human lineage (of the genus Homo) split from the chimpanzees — is unclear.  Scientists have debated whether the hobbit specimens represent an extinct species in the human family tree, perhaps a squat offshoot of Homo erectus, a 1.8-million-year-old hominid and the first to have body proportions comparable to those of modern Homo sapiens. More recent arguments suggest the hobbit specimens may have evolved from a pre-H. erectus hominin.

In fact, scientists have sought to learn more about the evolution of this hobbit, looking for clues, for instance, for hobbit ancestors on other Indonesian islands. In one study, detailed in the Jan. 14, 2016, issue of the journal Nature, a team of researchers looked for such clues on the Indonesian island of Sulawesi, situated between Flores and continental Asia. There, they found stone tools dating back at least 118,000 years, suggesting a hobbit ancestor lived on the island before modern humans showed up some 50,000 years ago, said study researcher errit van den Bergh, a paleontologist and zooarchaeologist at the University of Wollongong in Australia. The researchers aren't sure who this toolmaker was, though three possible candidates are: the hobbits, Homo erectus and the Denisovans, close relatives of Neanderthals.


 What did the hobbit look like?

Based on LB1, experts estimate H. floresiensis weighed between 35 and 79 lbs. (16 and 36 kg), according to a 2004 Nature article describing the specimen.

The hobbit specimens show a unique set of ancestral features (primitive traits retained from an ancestor species) and derived features (evolved features not shared by ancestors). They had skulls that resembled early Homo species, including a flat, sloping forehead and a short, flat face; however, their teeth and jaws more closely resembled Australopithecus (Homo ancestors), according to Nature.

Additionally, in a 2007 study in the journal Science, researchers closely analyzed three wrist bones of LB1 and found they more closely resembled those of apes than modern humans. This finding implied that H. floresiensis was indeed a separate species from modern humans.

In 2012, Susan Hayes, a senior research fellow at University of Wollongong, New South Wales, Australia, and her colleagues fleshed out the female hobbit's face by uploading information from 3D imaging scans of its skull into a computer graphics program. Compared with portraits of the hobbit by paleo-artists, Hayes' facial depiction of H. floresiensis showed more modern human features instead of monkey-like traits. The hobbit, in this depiction, doesn't have feminine doe eyes, and she lacks much of a forehead. What's more, the newly modeled portrait has a wider, shorter face and a comparatively modern nasal structure than previous face models, according to the researchers' 2013 study in the Journal of Archaeological Science.



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Origins of Indonesian Hobbits finally revealed


April 21, 2017

Summary:
    The most comprehensive study on the bones of Homo floresiensis, a species of tiny human discovered on the Indonesian island of Flores in 2003, has found that they most likely evolved from an ancestor in Africa and not from Homo erectus as has been widely believed.

https://www.sciencedaily.com/releases/2017/04/170421084917.htm

 


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Small height evolved twice on 'Hobbit' island of Flores

14 August 2018

https://www.bbc.com/news/science-environment-45049024




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Fast evolution explains the tiny stature of extinct ‘Hobbit’ from Flores Island

October 8, 2019

https://theconversation.com/fast-evolution-explains-the-tiny-stature-of-extinct-hobbit-from-flores-island-124747



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Bodies Keep Shrinking on This Island, and Scientists Aren't Sure Why

https://www.nytimes.com/2018/08/02/science/pygmies-flores-evolution.html



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Fast evolution explains the tiny stature of extinct ‘Hobbit’ from Flores Island

October 8, 2019

https://theconversation.com/fast-evolution-explains-the-tiny-stature-of-extinct-hobbit-from-flores-island-124747


 It’s not every day that scientists discover a new human species.

But that’s just what happened back in 2004, when archaeologists uncovered some very well-preserved fossil remains in the Liang Bua cave on Flores Island, Indonesia. The diminutive size of this new human species, Homo floresiensis, earned it the nickname “Hobbit.”

Shockingly, researchers believed it had survived until the end of the last Ice Age, some 18,000 years ago. That was much later than Neanderthals lived, later than any human species other than our own.

Almost immediately, interpretations of this Hobbit skeleton met with fierce criticism from both anthropologists and evolutionary biologists. The poor Hobbit was accused of being an example not of a small new human species, but an abnormal Homo sapiens, bearing any of a variety of growth and hormonal conditions. The Hobbit, many scientists decided, had no place among the giants of the human evolutionary record.


An artist’s interpretation of how H. floresiensis looked in life. Tim Evanson/Flickr, CC BY-SA

Yet she – yes, the Hobbit was later found to be a female – had her revenge. This tiny, small-brained creature stood just a bit more than three feet tall and had a brain as big as a chimp. But her place in the human ancestral line was cemented when researchers uncovered another tiny individual in Flores. This second, much older discovery debunked the idea that the Hobbit was a unique, abnormal Homo sapiens.

After 15 years of intense research, anthropologists now confidently date the Liang Bua individual to have lived between 60,000 and 90,000 years ago. Her much older cousins in Flores lived 700,000 years ago. This long reign testifies to the success of this tiny human species, no matter how small-statured and small-brained they were.

And this year anthropologists found a new dwarfed human species, christened Homo luzonensis, in the Philippines.

So why did tiny humans wind up living on these islands? For us biogeographers and evolutionary biologists, the answer was right in front of us: the island rule.
Island life and body size

Zoologist J. Bristol Foster originally proposed the island rule in 1964.

He’d noted that when a large-bodied species settles onto an island, it will tend to evolve to shrink in size – all the way to the point of leaving dwarf descendants. At the same time, the opposite will happen. Small-bodied species will evolve to be larger, producing gigantic daughter species.

There are spectacular cases of this island rule in action across the world. Think of pygmy elephants and mammoths from Mediterranean and Baja California islands, hippos that would barely outweigh a donkey in Cyprus, deer as tall as a pet dog in Crete, rats as big as a cow in the Caribbean and insects as long as a human hand in New Zealand.

Biologists have proposed various mechanisms that could be responsible for this evolutionary trend. A good motive might be the absence of natural predators on islands. A number of species, most notably elephants and hippos, fend predators off by virtue of their size, an expensive strategy when no killer is lurking in the dark. Also, on islands the scarce resource supply might favor smaller body size because smaller individuals can live with less.

Or it could be that smaller individuals with no predators just produce more offspring, which implies females start delivering earlier and at smaller size, investing less in growth and more in reproduction. This possibility is a likely explanation for how contemporary human pygmies evolved.

All of these options will eventually lead to changes in the genetic architecture that underlies body-size variation.

So, we asked, could the island rule be an explanation for small size of Homo floresiensis and Homo luzonensis? We thought probably yes.


Excavations in 2009 at Liang Bua cave, where Homo floresiensis was found. AP Photo/Achmad Ibrahim


Modeling generations on the island

The Hobbit’s most likely ancestor is Homo erectus, a species more than twice its size in terms of its brain and overall bulk. Based on the geological history of Flores and the oldest known fossils of Homo floresiensis, it seems the evolution of the new species must have occurred in less than about 300,000 years.

As evolutionary biologists, we are acquainted with the idea that Darwinian evolution is a slow and gradual process that takes place over very long timescales. Could such drastic change in body size happen this fast?

So our interdisciplinary research team developed a computer model to try to answer this basic question. It’s like a computer game that simulates body size evolution under biologically and ecologically realistic scenarios.

In our model, individuals colonize the island, grow to their adult body size according to how much food is available, give birth to a number of young and die. The basic rule of the game is that individuals that are closer to the “optimum” body size for the island in that moment will leave more descendants. Offspring inherit genes for large or small body size.

Generation after generation, new mutations may appear in the population and shift body size toward either higher or lower values. Occasionally, new individuals might even invade the island and mix with the residents. Another basic rule is that the initial small population cannot grow above the number the island’s resources might sustain.

Our colleagues, Earth systems scientists Neil Edwards and Phil Holden, used paleoclimatic data to tweak our model. Hotter and wetter times can support more people on the island, and would influence optimum body size at any given moment.

We started our simulations assuming that large-bodied Homo erectus arrived at the island and then evolved into a smaller species there. Since we just don’t know the exact numbers our model should crank through, we based them on estimates obtained from current human populations.

Because of this uncertainty, we ran our model thousands of times, each time using a random combination of all the parameters. Ultimately we were able to build a statistical distribution of how long it took for Homo erectus to become as small as Homo floresiensis.

A new species, in the blink of an evolutionary eye

After running 10,000 simulations, we were surprised to discover that in less than 350 generations, the process was complete. Thinking in terms of years, assuming a young female delivers a first baby at the average age of 15, that translates to about 10,000 years.

That may seem long for you and me. But from an evolutionary perspective, that’s the blink of an eye – a little more than a thousandth of Homo evolutionary history.

Of course we do not expect that all the features that make Homo floresiensis as unique as it is evolved that fast and at the same time. Yet, our simulation still shows, 300,000 years is far more than enough time for a new human species to arise.

Our work supports the idea that fast evolution is quite plausible under a realistic set of ecological parameters, and that natural selection may be a powerful force influencing body size on islands. And if Homo floresiensis is indeed a product of the island rule, she shows – yet again – that we humans tend to obey the same overall rules driving evolution in many other mammals.




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A New Genetic Study Suggests Modern Flores Island Pygmies and Ancient Hobbits Are Unrelated

August 2, 2018

The island dwarfism effect seems to have occurred independently in each population, thousands of years apart

https://www.smithsonianmag.com/science-nature/new-genetic-study-suggests-modern-flores-island-pygmies-and-ancient-hobbits-are-unrelated-180969858/



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Modern Flores Island pygmies show no genetic link to extinct ‘hobbits’


Aug. 2, 2018

Two pygmy populations on the same tropical island. One went extinct tens of thousands of years ago; the other still lives there. Are they related?

https://www.princeton.edu/news/2018/08/02/modern-flores-island-pygmies-show-no-genetic-link-extinct-hobbits



-----------------------------------------------------------



{It becomes confusing when you have scientists saying that Hobbits were related to Homo erectus, and now many scientists are stating that Hobbits are not related to Homo erectus.

The same goes for Hobbits being related to Homo floresiensis or not


I am still convinced the reason why Orientals and Mexicans look the way they do is because they must be from one of these species such as Denisovans, Homo erectus or even a distant cousin such as Homo floresiensis.

Some scientists will say that it was Homo erectus that spawned certain types of humans, and that
Hobbits were a subspecies that never fully made it into the human gene pool. It is debated if Hobbits were a subspecies, or Hobbits were their own distinct species. Hobbits were possibly on their own island, and why they were smaller than other primates.

Many question if Hobbits were a degenerative subspecies of Homo erectus.

If we had to guess what primates made up Orientals or brown people, I think that it would be Denisovans (this has been verified), Homo erectus or Homo floresiensis,  including Homo heidelbergensis or Homo habilis. We know that brown skinned people have more Denisovan DNA, and why many brown people are classified as an inferior subspecies.

Blacks might be Homo erectus and Homo heidelbergensis}.



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Africans have more archaic, ape like gene variants says controversial geneticist Dr. Shi Huang

 

2020 

 

Google Scholar Dr. Huang is a former Professor of Epigenetics and Evolution, Central South University, (Burnham Institute, UCSD).  Univ. of California San Diego of course, is well known for producing the popular series of human evolution lectures on YouTube.   Dr. Huang is now affiliated with the Central South University – CSU · Center for Medical Genetics in China.

 

During his early career at the Pew Institute, Dr. Huang [was] “studying the relationship between genetic diversity and epigenetic complexity and its role in common diseases and evolution… We proposed a novel hypothesis of genetic diversity and evolution, the Maximum Genetic Diversity (MGD) hypothesis… Genetic diversity of a species has an upper limit as set up by the epigenetic complexity levels…”

 

On Nov. 26, Shi Huang Tweeted:

 

“That Africans carry more ancestral alleles (=archaic or apes) has been well demonstrated by the rooting of phylogenetic trees in Africa for both autosomes and uniparental DNAs by using the outgroup rooting method.  Biological significance of this?  Eerie silence…”

 

In 2011 a research team tackled the precise question of African admixture with archaic hominids.

 

Michael Hammer (bio) is the Director of the University of Arizona Genetics Core (UAGC) and co-director of the UACC Genomics Shared Resource. He has joint appointments in Departments of Neurology and Ecology and Evolutionary Biology.

 

Also Dr. Jeff Wall, Professor of Epidemiology and Biostatistics (bio) Recent studies have focused on the contribution of archaic hominid ancestry in human populations.

 

Admixture from Homo naledi in present Africans?

Their findings (PNAS.org, Genetic Evidence for Archaic Admixture in Africans):

 

Here we use DNA sequence data gathered from 61 noncoding autosomal regions in a sample of three sub-Saharan African populations (Mandenka, Biaka, and San) to test models of African archaic admixture. We use two complementary approximate-likelihood approaches and a model of human evolution that involves recent population structure, with and without gene flow from an archaic population. Extensive simulation results reject the null model of no admixture and allow us to infer that contemporary African populations contain a small proportion of genetic material (≈2%) that introgressed ≈35 kya from an archaic population that split from the ancestors of anatomically modern humans ≈700 kya. [Emphasis added] 

 

Speculation from various top paleontologists such as John Hawks, Lee Berger, Chris Stringer and others has centered on likely suspects: Homo Heidelbergensis, Ergaster or even late Australopithecene, Homo naledi.

 

Hawks (lecture, 2017):

 

“We do know that African populations derive some small fraction of their DNA, possibly as much as 5%… from archaic lineages that we haven’t discovered…  What we don’t know is the identity of that lineage… It could be Naledi?”

 

Svante PÀÀbo on a possible archaic mix (lecture, 2018):

 

“There’s some indications of that in the genomes of present day Africans.”

 

And most recently, 2019, Arun Durvasula and Sriram Sankararaman from the University of California in Los Angeles confirmed up to 19% archaic Hominid DNA in modern Africans.  They have described the ancestor as a “ghost species” or quite possibly Homo naledi a “small-brained hominin” on the “African plains 250,000 years ago.” (IFL Science)

 

But as Professor Shi Huang implies, as the answer to the puzzle gets closer to being solved, an “eerie silence” has overtaken the paleontology, genetics and anthropology communities.


https://subspecieist.com/archaic-hominins/africans-ape-like-genetics/

 

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Blacks Aren’t Human

14 March, 2015


https://nationalvanguard.org/2015/03/blacks-arent-human/


------------------------------------------------------------


Negroid


https://en.wikipedia.org/wiki/Negroid


Physical features


In modern craniofacial anthropometry, Negroid describes features that typify skulls of black people. These include a broad and round nasal cavity; no dam or nasal sill; Quonset hut-shaped nasal bones; notable facial projection in the jaw and mouth area (prognathism); a rectangular-shaped palate; a square or rectangular eye orbit shape; a large interorbital distance; a more undulating supraorbital ridge; and large teeth.

According to George W. Gill and other modern forensic anthropologists, physical traits of Negroid crania are generally distinct from those of the Caucasoid and Mongoloid races. They assert that they can identify a Negroid skull with an accuracy of up to 95%. However, Alan H. Goodman cautions that this precision estimate is often based on methodologies using subsets of samples. He also argues that scientists have a professional and ethical duty to avoid such biological analyses since they could potentially have sociopolitical effects. Although widely used in forensic anthropology, some have also challenged the accuracy of craniofacial anthropometry vis-a-vis different human populations that have developed in close proximity to one another and those of mixed ethnic heritage.[30] Since the distinguishing racial traits are not set until puberty, they are also difficult to ascertain in preadolescent skulls.

Variation in craniofacial form between humans has been found to be largely due to differing patterns of biological inheritance. Modern cross-analysis of osteological variables and genome-wide SNPs has identified specific genes, which control this craniofacial development. Of these genes, DCHS2, RUNX2, GLI3, PAX1 and PAX3 were found to determine nasal morphology, whereas EDAR impacts chin protrusion.



Subraces


In the first half of the 20th century, the traditional subraces of the Negroid race were regarded as being the True Negro, the Forest Negro, the Bantu Negro, the Nilote, the Negrillo (also known as the African Pygmy), the Khoisan (often historically referred to as Hottentot and Bushman), the Negrito (also known as the Asiatic Pygmy), and the Oceanic Negroids (consisting of the Papuan and Melanesian).[

By the 1960s, some scholars regarded the Khoisan as a separate race known as the Capoid race, while others continued to regard them as a Negroid subrace. The term "Congoid" was frequently used interchangeably with "Negroid", with the main difference being that Congoid excluded the Capoid taxon.




































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 Lisar neolithic Woman


https://www.kenniskennis.com/site/sculptures/Lisar%20Neolithic%20Woman/



 




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 Homo Erectus Naturalis

https://www.kenniskennis.com/site/sculptures/Homo%20Erectus%20Naturalis/








 






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 Neanderthal Child

https://www.kenniskennis.com/site/sculptures/Neanderthal%20Child/















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 Pestera cu Oase


https://www.kenniskennis.com/site/sculptures/Pestera%20cu%20Oase/





 












 ----------------------------------------------------------------------







 Neanderthal Gibraltar


https://www.kenniskennis.com/site/sculptures/Neanderthal%20Gibraltar/




 







----------------------------------------------------------



Angolan Physician: “Sexual Relationships Between Humans and Chimpanzees Are Fairly Common in the Region”


14 March, 2020

https://nationalvanguard.org/2020/03/angolan-physician-sexual-relationships-between-humans-and-chimpanzees-are-fairly-common-in-the-region/



------------------------------------------------------------



 Morrissey reignites racism row by calling Chinese a 'subspecies'

2010

Remark came in context of an attack on China's animal welfare record, with singer having been criticised on a number of previous occasions for negative race comments


https://www.theguardian.com/music/2010/sep/03/morrissey-china-subspecies-racism



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A new species of Homo from the Late Pleistocene of the Philippines


10 April 2019


Abstract

A hominin third metatarsal discovered in 2007 in Callao Cave (Northern Luzon, the Philippines) and dated to 67 thousand years ago provided the earliest direct evidence of a human presence in the Philippines. Analysis of this foot bone suggested that it belonged to the genus Homo, but to which species was unclear. Here we report the discovery of twelve additional hominin elements that represent at least three individuals that were found in the same stratigraphic layer of Callao Cave as the previously discovered metatarsal. These specimens display a combination of primitive and derived morphological features that is different from the combination of features found in other species in the genus Homo (including Homo floresiensis and Homo sapiens) and warrants their attribution to a new species, which we name Homo luzonensis. The presence of another and previously unknown hominin species east of the Wallace Line during the Late Pleistocene epoch underscores the importance of island Southeast Asia in the evolution of the genus Homo.

https://www.nature.com/articles/s41586-019-1067-9

 


------------------------------------------------------------



Previously unknown human species found in Asia raises questions about early hominin dispersals from Africa

 10 April 2019

Excavations in southeast Asia have unearthed a previously unreported hominin species named Homo luzonensis. The discovery has implications for ideas about early hominin evolution and dispersal from Africa.

https://www.nature.com/articles/d41586-019-01019-7


------------------------------------------------------------

 

 

 Pacific Islanders Appear to Be Carrying The DNA of an Unknown Human Species 

2016

https://www.sciencealert.com/pacific-islanders-appear-to-be-carrying-the-dna-of-an-unknown-human-species

 

------------------------------------------------------------




Are races human subspecies?

https://www.quora.com/Are-races-human-subspecies


--------------------------------------------------------



Are different races subspecies?

https://askabiologist.asu.edu/questions/human-races


--------------------------------------------------------



The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs

 Jun 11, 2019

https://elifesciences.org/articles/42866/figures



----------------------------------------------------------




 The ‘Stoned Ape’ Theory Might Explain Our Extraordinary Evolution


A scientist resurfaces a psychedelic retelling of human evolution.


https://getpocket.com/explore/item/the-stoned-ape-theory-might-explain-our-extraordinary-evolution?utm_source=pocket-newtab



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A PhD student proved one of Darwin's theories of evolution 140 years after his death

March 19, 2020

https://www.cnn.com/2020/03/19/world/darwin-theory-proved-scn-trnd/index.html

Darwin's subspecies theory

To understand the significance of this development, it's best to start with a refresher on the following taxonomy (or naming conventions): genus, species and subspecies.

    A genus is a group of animals with similar traits. This can include multiple species. For example, most bears belong to the genus Ursus.
    A species is a group of similar animals that can interbreed and exchange genes to reproduce. The brown bear is a species under the Ursus umbrella.
    A subspecies is a group within a species that looks phenotypically different from the rest of the species and has its own breeding range that doesn't overlap with the rest of the species. A grizzly bear is a subspecies of brown bear.

Darwin predicted that species in a larger genus should also include more subspecies. But he never elaborated on why.



-------------------------------------------------------------------------------



A Scientist Just Proved One of Darwin's Evolution Theories, 161 Years Later

The discovery could help protect endangered species.

Mar 23, 2020

https://www.popularmechanics.com/science/a31898738/scientist-proves-darwin-evolution-theory/



An anthropology doctoral student at the University of Cambridge has analyzed centuries of naturalist data to prove a longstanding theory from Charles Darwin’s work. The crux of the work is in the relationship between how species evolve into subspecies and whether that presages new species.

Laura van Holstein said in a statement that the way subspecies emerge depends on whether the species is by land, by air, or by sea. “Subspecies form, diversify and increase in number in a different way in non-terrestrial and terrestrial habitats, and this in turn affects how subspecies may eventually become species,” she said.

We see this kind of branching represented in concurrent species, like the isolated and specialized groups of finches Darwin himself studied in the Galapagos Islands. One of the most familiar examples might be the wildcat, which refers to one of two species that are very closely related—domestic cat ancestor the African wildcat, and the European wildcat. In turn, each species has subspecies. These are all totally separate from specific kinds of wild cats like Pallas cats or fishing cats.




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HUMAN DIVERSITY - GO DEEPER

There is not one gene, trait, or characteristic that distinguishes all members of one race from all members of another. We can map any number of traits and none would match our idea of race. This is because modern humans haven't been around long enough to evolve into different subspecies and we've always moved, mated, and mixed our genes. Beneath the skin, we are one of the most genetically similar of all species.

Lots of animals are divided into subspecies. Why doesn't it make sense to group humans the same way?

https://www.pbs.org/race/000_About/002_04-background-01-11.htm

 

--------------------------------------------------------------------------------

 

 
Mungo Man

http://www.convictcreations.com/aborigines/prehistory.htm


Turning evolution upside down

In the study of human evolution, Australia has not traditionally believed to have much to offer; however, the skeletal record has thrown up a few spanners in the works that may one day transform beliefs about where humans came from.

One of these spanners is Mungo Man, who was discovered in 1974 in the dry lake bed of Lake Mungo in west NSW. Mungo Man was a hominin who was estimated to have died 62,000 years ago and was ritually buried with his hands covering his penis. Anatomically, Mungo Man's bones were distinct from other human skeletons being unearthed in Australia. Unlike the younger skeletons that had big-brows and thick-skulls, Mungo Man's skeleton was finer, and more like modern humans.

The ANU's John Curtin School of Medical Research found that Mungo Man's skeleton's contained a small section of mitochondrial DNA. After analysing the DNA, the school found that Mungo Man's DNA bore no similarity to the other ancient skeletons, modern Aborigines and modern Europeans. Furthermore, his mitochondrial DNA had become extinct. The results called into question the 'Out of Africa' theory of human evolution. If Mungo Man was descended from a person who had left Africa in the past 200,000 years, then his mitochondrial DNA should have looked like all of the other samples.

 


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A 146,000-Year-Old Fossil Dubbed ‘Dragon Man’ Might Be One of Our Closest Relatives

June 25, 2021

A mysterious Middle Pleistocene skull from a Chinese well has inspired debate among paleoanthropologists

https://www.smithsonianmag.com/science-nature/146000-year-old-fossil-dubbed-dragon-man-might-be-one-our-closest-relatives-180978062/



 

 


 

 


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Israeli Archaeologists Think New Chinese Hominin 'Dragon Man' May Be Homo Nesher

Phylogenetic analysis led a team to posit that a skull found in 1933 is an unknown species of hominin. Israeli researchers think it looks like an early Neanderthal

June 27, 2021

https://www.haaretz.com/israel-news/israel-archaeologists-chinese-hominin-dragon-man-may-be-homo-nesher-1.9937326

 

 

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An Indigenous people in the Philippines have the most Denisovan DNA

August 12, 2021

Indigenous Ayta Magbukon people get 5 percent of their DNA from the mysterious ancient hominids

Denisovans are an elusive bunch, known mainly from ancient DNA samples and traces of that DNA that the ancient hominids shared when they interbred with Homo sapiens. They left their biggest genetic imprint on people who now live in Southeast Asian islands, nearby Papua New Guinea and Australia. Genetic evidence now shows that a Philippine Negrito ethnic group has inherited the most Denisovan ancestry of all. Indigenous people known as the Ayta Magbukon get around 5 percent of their DNA from Denisovans, a new study finds.

This finding fits an evolutionary scenario in which two or more Stone Age Denisovan populations independently reached various Southeast Asian islands, including the Philippines and a landmass that consisted of what’s now Papua New Guinea, Australia and Tasmania. Exact arrival dates are unknown, but nearly 200,000-year-old stone tools found on the Indonesian island of Sulawesi may have been made by Denisovans (SN: 1/13/16). H. sapiens groups that started arriving around 50,000 years ago or more then interbred with resident Denisovans.

Evolutionary geneticists Maximilian Larena and Mattias Jakobsson, both at Uppsala University in Sweden, and their team describe the new evidence August 12 in Current Biology.

Even as the complexities of ancient interbreeding in Southeast Asia become clearer, Denisovans remain a mysterious crowd. “It’s unclear how the different Denisovan groups on the mainland and on Southeast Asian islands were related [to each other] and how genetically diverse they were,” Jakobsson says.

https://www.sciencenews.org/article/indigenous-people-philippines-denisovan-dna-genetics

 

 

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Ancient Denisovan DNA excavated in modern Pacific Islanders

Substantial genomic remnants of the extinct Denisovans recovered in Oceania populations

    March 17, 2016

https://www.sciencedaily.com/releases/2016/03/160317150805.htm

 

 

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High Covid-19 rates for Pacific islanders in the US

April 2020

https://www.rnz.co.nz/international/pacific-news/415195/high-covid-19-rates-for-pacific-islanders-in-the-us

 


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Pacific Islander Death Rate From Covid Still The Worst In LA County (Though Not As High As Originally Thought)

Jul 16, 2020

https://laist.com/news/pacific-islander-native-hawaiian-california-los-angeles-covid-19-coronavirus

 

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Hawaii 62 Percent Fully Vaccinated & Huge Covid-19 Surge And Hospitalizations Spike

30 Aug 2021

https://ugetube.com/watch/hawaii-62-percent-fully-vaccinated-huge-covid-19-surge-and-hospitalizations-spike-mp4_N3PwsVbSGPYUI3R.html

 

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Pacific Islanders In Oregon Have The Highest Rate of COVID-19

April 23, 2020

https://www.civilbeat.org/beat/pacific-islanders-in-oregon-have-the-highest-rate-of-covid-19/

 

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Colorado’s Pacific Islanders Display Higher COVID-19 Death Rates

April 14, 2020

https://asamnews.com/2020/04/14/colorados-native-hawaiian-pacific-islanders-display-higher-covid-19-coronavirus-death-rates/

 

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Pacific Islanders Have The Highest COVID-19 Death Rate In Hawaii

August 24, 2020

Filipinos in Hawaii have the next-highest death rate, composing 24% of deaths but only 16% of the population.

https://www.civilbeat.org/2020/08/pacific-islanders-have-the-highest-covid-19-death-rate-in-hawaii/

 

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Track us better: Overlooked Pacific Islanders hit hard by coronavirus

May 5, 2020

https://www.abc10.com/article/news/health/coronavirus/overlooked-pacific-islanders-hit-hard-by-coronavirus/103-b21e19e1-e96a-447b-8a8c-0d3ac6a7e04b


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Genetic Evidence Suggests a Denisovan Presence in the Pacific Islands

24 April, 2021

 

A new genetic study has provided important data to evolutionary scientists seeking to trace the migratory movements and cultural interactions of the people who settled the South Pacific islands of Oceania. Most intriguing is a discovery that seems to link people living in the highlands of Papua New Guinea (PNG) with the famed Denisovans, the long-extinct cousins of the Neanderthals who were believed to have resided exclusively in East Asia. While many Pacific Islands show traces of Denisovan DNA from encounters that occurred before their ancestors migrated to their current homes, the latest evidence suggests more recent interbreeding, dating to the post-island settlement era. 



https://www.ancient-origins.net/news-history-archaeology/pacific-islands-0015238

 

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A Pygmy Negrito Tribe Is Found to be 5% Archaic Denisovan

August 17, 2021

A Pygmy Negrito tribe in the Philippines is found to have 5% of their DNA descended from the archaic quasi-extinct Denisovan mystery quasi-species.

Denisovans are somewhat as if they are to the East Eurasian/Pacific what the much more famous Neanderthals are to West Eurasia: a hominid group distinct enough from anatomically modern humans to be considered a distinct species, but close enough to have mated with modern humans and, apparently, contributed some useful genes to many (but not all) modern genomes. (Geneticists also now theorize that modern sub-Saharans have similar single digit percentages of genetic ancestry from one or more still-undiscovered archaic “ghost populations.”

Denisovans were unknown until a decade ago when a few bones were found in Siberia and their DNA extracted.

https://www.unz.com/isteve/a-pygmy-negrito-tribe-is-found-to-be-5-archaic-denisovan/

 

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Pacific Islanders Appear to Be Carrying The DNA of an Unknown Human Species

25 OCTOBER 2016

https://www.sciencealert.com/pacific-islanders-appear-to-be-carrying-the-dna-of-an-unknown-human-species

 

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Some Pacific Islanders Have DNA Not Linked To Any Known Human Ancestor

October 31, 2016

Researchers have now uncovered the DNA of a previously unknown group of hominids.

https://allthatsinteresting.com/pacific-islanders-ancestor

 

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Some West Africans Have DNA Not Linked To Any Known Human Ancestor

April 3, 2018

Using a new method, researchers found mysterious "ghost" DNA in West African Yoruba population.

https://allthatsinteresting.com/west-africans-unknown-dna

 

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Black People Are Four Times More Likely To Die From Coronavirus, U.K. Statistics Show

May 7, 2020

https://www.forbes.com/sites/isabeltogoh/2020/05/07/black-people-are-four-times-more-likely-to-die-from-coronavirus-uk-statistics-show/#78777b124fd4

 

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 Scientists Find a Mysterious 'Ghost Lineage' In the DNA of West Africans

February 14, 2020

Researchers find evidence that a group of still-unknown humans interbred with our ancestors.

https://www.discovermagazine.com/planet-earth/genetic-traces-of-mysterious-human-lineage-detected-in-people-living-in

 

 

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The 'Ghosts' of 2 Unknown Extinct Human Species Have Been Found in Modern DNA

 17 JULY 2019


https://www.sciencealert.com/two-unknown-species-of-ancient-extinct-hominids-have-been-identified-in-modern-dna

 


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Ghost population

https://en.wikipedia.org/wiki/Ghost_population

A ghost population is a population that has been inferred through using statistical techniques.

Population studies

In 2004, it was proposed that Maximum likelihood or Bayesian approaches that estimate the migration rates and population sizes using coalescent theory can use datasets which contain a population that has no data. This is referred to as a "ghost population". The manipulation allows exploration in the effects of missing populations on the estimation of population sizes and migration rates between two specific populations. The biases of the inferred population parameters depend on the magnitude of the migration rate from the unknown populations. The technique for deriving ghost populations attracted criticism because ghost populations were the result of statistical models, along with their limitations.

Population genetics

Further information: Interbreeding between archaic and modern humans

In 2012, DNA analysis and statistical techniques were used to infer that a now-extinct human population in northern Eurasia had interbred with both the ancestors of Europeans and a Siberian group that later migrated to the Americas. The group was referred to as a ghost population because they were identified by the echoes that they leave in genomes — not by bones or ancient DNA.[3] In 2013, another study found the remains of a member of this ghost group, fulfilling the earlier prediction that they had existed.

According to a study published in 2020, there are indications that 2% to 19% (or about ≃6.6 and ≃7.0%) of the DNA of four West African populations may have come from an unknown archaic hominin which split from the ancestor of humans and Neanderthals between 360 kya to 1.02 mya. However, the study also suggests that at least part of this archaic admixture is also present in Eurasians/non-Africans, and that the admixture event or events range from 0 to 124 ka B.P, which includes the period before the Out-of-Africa migration and prior to the African/Eurasian split (thus affecting in part the common ancestors of both Africans and Eurasians/non-Africans).[6][7][8] Another recent study, which discovered substantial amounts of previously undescribed human genetic variation, also found ancestral genetic variation in Africans that predates modern humans and was lost in most non-Africans.

In 2015, a study of the lineage and early migration of the domestic pig found that the best model that fitted the data included gene flow from a ghost population during the Pleistocene that is now extinct.


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The Old, Weird Africa: Ancient Pygmy DNA Uncovered by David Reich

January 22, 2020

https://www.amren.com/news/2020/01/the-old-weird-africa-ancient-pygmy-dna-uncovered-by-david-reich/

 

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New look at archaic DNA rewrites human evolution story

August 7, 2017

https://www.sciencedaily.com/releases/2017/08/170807155158.htm

A new method for analyzing DNA sequence data has been developed to reconstruct early history of archaic human populations, revealing an evolutionary story that contradicts conventional wisdom about modern humans, Neanderthals and Denisovans. They found that Neanderthal-Denisovan lineage nearly went extinct after separating from modern humans. Just 300 generations later, Neanderthals and Denisovans diverged around 744,000 years ago. The global Neanderthal population grew to tens of thousands of individuals living in fragmented, isolated populations. 


 

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 Grimaldi man

 

https://en.wikipedia.org/wiki/Grimaldi_man


Grimaldi man is the name formerly given to two human skeletons of the Upper Paleolithic discovered in Italy in 1901. The remains are now recognized as representing two individuals, and are dated to ca. 26,000 to 22,000 years ago and classified as part of the wider European early modern humans population of the late Aurignacian to early Gravettian.

Because of their early discovery, there is a long history of interpretation of the fossils. Notably, the remains were originally classified as Negroid by Boule and Vallois (1921). This identification has been obsolete since at least the 1960s, but it was controversially revived in the 1980s as part of the Afrocentrism propagated by Cheikh Anta Diop.

Physical characteristics

The Grimaldi skeletons were very different from the finds that had been unearthed in Europe until then. Unlike the robust Neanderthals, the Grimaldi skeletons were slender and gracile, even more so than the Cro-Magnon finds from the same cave system. The Grimaldi people were small. While an adult Cro-Magnon generally stood over 170 cm tall (large males could reach 190 cm), neither of the two skeletons stood over 160 cm. The boy was smallest at a mere 155 cm.

The two skulls had rather tall braincases, unlike the long, low skulls found in Neanderthals and to a lesser extent in Cro-Magnons. The faces had wide nasal openings and lacked the rectangular orbitae and broad complexion so characteristic of Cro-Magnons. These traits, combined with what de Villeneuve interpreted as prognathism led the discoverers to the conclusion that the Grimaldi man had been of a "negroid" type. Some traits did not fit the picture though. The nasal bone had a high nasal bridge, like that of Cro-Magnons and modern Europeans and was very unlike those of more tropical groups. The two rises of the frontal bone in the forehead were separate rather than forming a single median rise, another European trait. The cranial capacity was also quite large for their size. 


 

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Boskop Man

https://en.wikipedia.org/wiki/Boskop_Man

The Boskop Man is an anatomically modern human fossil of the Middle Stone Age (Late Pleistocene) discovered in 1913 in South Africa. The fossil was at first described as Homo capensis and considered a separate human species by Broom (1918), but by the 1970s this "Boskopoid" type was widely recognized as representative of the modern Khoisan populations.

Cranial capacity

The Boskop Man fossils are notable for their unusually large cranial capacities, with reported cranial-capacity ranges between 1,700 and 2,000 cm3.

This was addressed in the book Big Brain: The Origins and Future of Human Intelligence (2008) by neurologists Gary Lynch and Richard Granger, who claimed the large brain size in Boskop individuals might be indicative of particularly high general intelligence. Anthropologist John Hawks harshly criticized the depiction of the Boskop fossils in the book and in the book's review article in Discover magazine. 


 

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Earliest evidence of humans outside Africa

11 July 2018

https://www.bbc.com/news/science-environment-44797323

 

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Early European modern humans

https://en.wikipedia.org/wiki/Early_European_modern_humans

Early European modern humans (EEMH) or Cro-Magnons were the first early modern humans (Homo sapiens) to settle in Europe, continuously occupying the continent possibly from as early as 48,000 years ago. They interacted and interbred with the indigenous Neanderthals (H. neanderthalensis), who went extinct 40 to 35 thousand years ago; and from 37,000 years ago onwards, all EEMH descended from a single founder population which contributes ancestry to present-day Europeans. EEMH produced Upper Palaeolithic cultures, the first major one being the Aurignacian, which was succeeded by the Gravettian by 30,000 years ago. The Gravettian split into the Epi-Gravettian in the east and Solutrean in the west, due to major climate degradation during the Last Glacial Maximum (LGM), peaking 21,000 years ago. As Europe warmed, the Solutrean evolved into the Magdalenian by 20,000 years ago, and these peoples recolonised Europe. The Magdalenian and Epi-Gravettian gave way to Mesolithic cultures as big game animals were dying out and the Last Glacial Period drew to a close.

EEMH were anatomically similar to present-day Europeans, but were more robust, having broader and shorter faces, more prominent brow ridges, and bigger teeth. Compared to most present-day Europeans, EEMH had shorter upper jaws, more horizontally oriented cheekbones, and more rectangular eye sockets, which are more frequent in East Asian populations. The first EEMH would have probably had dark skin; natural selection for lighter skin would not begin until 30,000 years ago, and whiter skin would not become prevalent in Europe until the Bronze Age. Before the LGM, EEMH had overall low population density, tall stature similar to post-industrial humans, expansive trade routes stretching as long as 900 km (560 mi), and hunted big game animals. EEMH had much higher populations than the Neanderthals, possibly due to higher fertility rates; life expectancy for both species was typically under 40 years. Following the LGM, population density increased as communities travelled less frequently (though for longer distances), and the need to feed so many more people in tandem with the increasing scarcity of big game caused them to rely more heavily on small or aquatic game, and more frequently participate in game drive systems and slaughter whole herds at a time. The EEMH arsenal included spears, spear-throwers, harpoons, and possibly throwing sticks and Palaeolithic dogs. EEMH likely commonly constructed temporary huts while moving around, and Gravettian peoples notably made large huts on the East European Plain out of mammoth bones.

EEMH are well renowned for creating a diverse array of artistic works, including cave paintings, Venus figurines, perforated batons, animal figurines, and geometric patterns. They may have been decorating their bodies with ochre crayons and perhaps tattoos, scarification, and piercings. The exact symbolism of these works remains enigmatic, but EEMH are generally (though not universally) thought to have practiced shamanism, in which cave art — specifically of those depicting human/animal hybrids — played a central part. They also wore decorative beads, and plant-fibre clothes dyed with various plant-based dyes, which were possibly used as status symbols. For music, they produced bone flutes and whistles, and possibly also bullroarers, rasps, drums, idiophones, and other instruments. They buried their dead, though possibly only people which had achieved or were born into high status received burial.

Remains of Palaeolithic cultures have been known for centuries, but they were initially interpreted in a creationist model, wherein they represented antediluvian peoples which were wiped out by the Great Flood. Following the conception and popularisation of evolution in the mid-to-late 19th century, EEMH became the subject of much scientific racism, with early race theories allying with Nordicism and Pan-Germanism. Such historical race concepts were overturned by the mid-20th century. During the first wave feminism movement, the Venus figurines were notably interpreted as evidence of some matriarchal religion, though such claims had mostly died down in academia by the 1970s.



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Neanderthal vs. Cro-Magnon: What's the Difference?

September 6, 2013

https://www.mentalfloss.com/article/19428/neanderthal-vs-cro-magnon-whats-difference

 

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Europe's Ancestors: Cro-Magnon 28,000 Years Old Had DNA Like Modern Humans

    July 16, 2008

https://www.sciencedaily.com/releases/2008/07/080715204741.htm




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Why Don't We Call Them 'Cro-Magnon' Anymore?

November 14, 2019

'Cro-Magnon' Versus 'Anatomically Modern Humans'


https://www.thoughtco.com/we-dont-call-them-cro-magnon-170738

 What Are Cro-Magnons?

"Cro-Magnon" is the name scientists once used to refer to what are now called Early Modern Humans or Anatomically Modern Humans—people who lived in our world at the end of the last ice age (ca. 40,000–10,000 years ago); they lived alongside Neanderthals for about 10,000 of those years. They were given the name "Cro-Magnon" because, in 1868, parts of five skeletons were discovered in a rock shelter of that name, located in the famous Dordogne Valley of France.

In the 19th century, scientists compared these skeletons to Neanderthal skeletons that had been found earlier in similarly dated sites like Paviland, Wales and a little later at Combe Capelle and Laugerie-Basse in France. They decided that the findings were different enough from the Neanderthals—and from us—to give them a different name.

Why Don't We Still Call Them Cro-Magnon?

A century and a half of research since then has led scholars to change their minds. The new belief is that the physical dimensions of the so-called "Cro-Magnon" are not sufficiently different enough from modern humans to warrant a separate designation. Instead, scientists today use "Anatomically Modern Human" (AMH) or "Early Modern Human" (EMH) to designate the Upper Paleolithic human beings who looked a lot like us but did not have the complete suite of modern human behaviors (or rather, who were in the process of developing those behaviors).

Another reason for the change is that the term "Cro-Magnon" doesn't refer to a particular taxonomy or even a particular group located in a particular place. It was simply not precise enough, and so most paleontologists prefer to use AMH or EMH to refer to the immediate ancestor hominins we modern humans evolved from.

Identifying Early Modern Humans

As recently as 2005, the way scientists differentiated between modern humans and early modern humans was by looking for subtle differences in their physical characteristics: The two are generally very similar physically, but EMH are a bit more robust, particularly in femora (upper leg bones). These slight differences have been attributed to the shift away from long-distance hunting strategies to sedentism and agriculture.

However, those types of speciation differentiation have all but disappeared from the scientific literature. Considerable overlap in physical measurements of various human forms has made it difficult to draw distinctions. More important is the successful recovery of ancient DNA from modern humans, early modern humans, Neanderthals, and the new human species that was first identified with mtDNA: Denisovans. This new method of differentiation—genetics—is far more definitive than using physical characteristics.

The Genetic Makeup of Early Modern Humans

Neanderthals and early modern humans shared our planet for several thousand years. One result of the new genetic studies is that both Neanderthal and Denisovan genomes have been found in non-African modern individuals. That suggests that where they came into contact, Neanderthals, Denisovans, and anatomically modern humans interbred.

Levels of Neanderthal ancestry in modern humans vary from region to region, but all that can be firmly concluded today is that the relationships existed. Neanderthals all died out between 41,000–39,000 years ago—probably at least partly a result of competition with early modern humans—but their genes and those of the Denisovans live on within us.


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Surprising DNA found in ancient people from southern Europe

March 14, 2019

https://www.nationalgeographic.com/science/article/ancient-iberians-dna-from-steppe-men-spain

A study of 8,000 years of genetics from Spain and Portugal yields a surprisingly complex picture of the inhabitants' ancestry.

Since the beginning of human migration, the Iberian Peninsula—home of modern-day Spain and Portugal—has been a place where the cultures of Africa, Europe, and the Mediterranean have mingled.

In a new paper in the journal Science, a group of 111 population geneticists and archaeologists charted 8,000 years of genetics in the region. They paint a picture that shows plenty of genetic complexity, but that also hints at a single mysterious migration about 4,500 years ago that completely shook up ancient Iberians’ DNA.

The team searched DNA evidence for clues to how and when various populations became part of the Iberian Peninsula’s gene pool. They sequenced the genomes of 271 ancient Iberians, then combined that information with previously published data about 132 other ancient peninsula dwellers.

The men from the steppes

Beginning in the Bronze Age, the genetic makeup of the area changed dramatically. Starting in about 2,500 B.C., genes associated with people from the steppes near the Black and Caspian seas, in what is now Russia, can be detected in the Iberin gene pool. And from about 2,500 B.C. much of the population’s DNA was replaced with that of steppe people.

The “Steppe Hypothesis” holds that this group spread east into Asia and west into Europe at around the same time—and the current study shows that they made it to Iberia, too. Though 60 percent of the region’s total DNA remained the same, the Y chromosomes of the inhabitants were almost entirely replaced by 2,000 B.C. That suggests a massive influx of men from the steppes, since Y chromosomes are carried only by men.

“It looks like the influence was very male dominated,” says Miguel Vilar, a genetic anthropologist who serves as senior program officer for the National Geographic Society.

Who were these men—and did they come in peace? Vilar, who was not involved with the study, speculates that the steppe men may have come on horses bearing bronze weapons, hence ushering in the Bronze Age to the area. He compares the migration to the one the indigenous peoples of North and South America faced when the first Europeans landed in the 1490s.

“It shows that you could have a migration all the way across the whole continent (of Europe) and still have a heavy influence on this far extreme,” he says.

Although bronze came into use in Iberia around that time, no other distinct traces of steppe culture have yet been found. The study did show that people in present-day Basque, who speak Western Europe’s only non-Indo-European language, carry genetic markers closely related to those of the steppe people. And unlike modern Spaniards, modern-day Basques don’t show the same amount of genetic mixing that happened on the peninsula over the centuries.

The team also found a single individual with North African DNA from a site in the middle of Iberia. His bones date to about 2,500 B.C.

“At the beginning I thought it was a mistake,” says Iñigo Olalde, a population geneticist who led the study.

When he replicated his work, it checked out. The presence of that lone African suggests early, sporadic interchange between Iberia and North Africa, making sense of archaeological discoveries of African ivory at Copper-Age Iberian digs. But the team thinks that North African ancestry only became widespread in Iberia in about the last 2,000 years.

Ice Age diversity

The study forms a complex picture of the genetic history of Spain—one that’s reinforced in a companion piece published in the journal Current Biology. In that study, researchers from Spain and Germany found that hunter-gatherers and farmers living on the Iberian Peninsula also were more genetically diverse than previously thought. They found evidence that different hunter-gatherer cultures mixed on the warm Iberian Peninsula, which they used as an Ice Age refuge 19,000 years ago. Newer farmers to the area mixed with the hunter-gatherers later.

”The DNA was a surprise,” says doctoral student Vanessa Villalba-Mouco, an archaeogeneticist who led the research for the Max Planck Institute for the Science of Human History in Germany and the University of Zaragoza in Spain. “Clues about what happened in that moment help us understand the evolution of the next period. We need to sample more individuals to know their history in a more accurate way.”

Ancient DNA work “is helping us deconstruct the idea that that we have distinct geographic populations like Africans or Asians or Europeans,” says Vilar. “Not only are people living in areas like Iberia heterogeneous, but they were the product of different waves of migration themselves.”

For Olalde, the work was an unprecedented chance to explore the genetic history of the place he calls home. “Being able to do this study was a dream for me,” he says.

And working with a large sample sizes—rare in studies that must rely on DNA extracted from bone that is thousands of years old—was particularly exciting for the Olalde, who works in the David Reich Lab at Harvard Medical School. “Being able to analyze nearly 400 individuals is crazy. Thanks to them, we now have a much richer picture of all the different peoples who inhabited the Iberian Peninsula and how they shaped present-day populations.”


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Europeans, Africans have different immune systems, and Neanderthals are partly to thank


2016

https://www.sciencedaily.com/releases/2016/10/161020142948.htm


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Turns out blacks are a completely different subspecies of human after all proven in genetic study

2014

https://www.godlikeproductions.com/forum1/message2610338/pg1?c1=1&c2=1&disclaimer=Continue


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The Truth About The Homo Sapiens Subspecies That Went Extinct

Sept. 18, 2020

https://www.grunge.com/248920/the-truth-about-the-homo-sapiens-subspecies-that-went-extinct/


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Smaller Than Species: Subspecies, Races, and Breeds

https://www.dummies.com/education/science/smaller-than-species-subspecies-races-and-breeds/

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What's the difference between a race and a subspecies?

https://www.quora.com/Whats-the-difference-between-a-race-and-a-subspecies?share=1


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Genomic Comparisons Reveal Microevolutionary Differences in Mycobacterium abscessus Subspecies

23 October 2017

https://www.frontiersin.org/articles/10.3389/fmicb.2017.02042/full


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Evolutionary Genomics of Salmonella enterica Subspecies

https://mbio.asm.org/content/4/2/e00579-12.abstract



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Subspecies and the philosophy of science

25 March 2015


https://bioone.org/journals/the-auk/volume-132/issue-2/AUK-15-1.1/Subspecies-and-the-philosophy-of-science/10.1642/AUK-15-1.1.full



The Subspecies Debate

No taxonomic rank has been more maligned or misunderstood than the subspecies. Attacks on this rank's value date back to the early 1950s (e.g., Wilson and Brown 1953), the principal argument against it being that subspecies are “arbitrary,” a charge that could be levied with equal force at the genus, family, or any other higher rank (which tend not to correspond across phyla or kingdoms; Avise and Mitchell 2007). Although there may be merit in setting aside the whole of the Linnaean hierarchy (Ereshefsky 2001), it remains the dominant way in which we classify organisms and, hence, communicate about ecological communities, phylogenetic relationships, biogeographic processes, and a host of other basic topics in ecology and evolutionary biology. Linnaeus's scheme is likely to be with us for years to come, so we ought to determine how best to standardize its use across all organisms and ensure that classification into established ranks follows a logical and repeatable procedure. This last point, repeatability, is an often neglected cornerstone of the scientific process. Many criticized Sibley and Ahlquist (1990) when they opted to allow particular levels of Δt50, a measure of the difference in temperature at which DNA heteroduplexes and homoduplexes denature, to assign ranks of family, tribe, order, and the like—yet, if nothing else, the procedure and the assignment were repeatable.

Strides have been made to reduce subjectivity in other ranks, most notably that of species, a rank even Darwin refused to define despite its appearing prominently in the title of his famous book. Darwin considered species limits arbitrary, and modern debates about the relative virtues of particular species concepts have done little to address the inherent subjectivity of, say, what exactly it means to be reproductively isolated (how much hybridization is too much?) or how exactly to identify a clade that corresponds to something above an isolated population yet below a wholesale radiation (i.e. the “diagnosable clusters” of the phylogenetic species concept; Cracraft 1983). A crucial step in the direction of objectivity has been a recent emphasis on effect size (of trait variability) to determine species and subspecies limits (Patten 2010, Tobias et al. 2010, Winker 2010). Akin to Sibley and Ahlquist's (1990) Δt50 thresholds, the idea is that differences of a particular magnitude—a large effect size—for a trait being examined will indicate whether 2 populations are 2 species (Tobias et al. 2010). A similar argument can be made to assess whether 2 populations correspond to 2 subspecies (Patten 2010), provided it is clear that there are distinct thresholds that determine species limits and subspecies limits.


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Subspecies: what should they be in the face of cryptic species

https://www.researchgate.net/post/Subspecies_what_should_they_be_in_the_face_of_cryptic_species



Some of the comments seem to be based on misinterpretation of the terms "species" and "subspecies". Species is defined by evolutionary separation ("evolving separately from others and with its own unitary evolutionary role and tendencies"), i.e. by permanently broken gene flow (no, or at most only occasional and/or ineffective hybridization); if such [group of] population[-s] does not show clear morphological differences it is called "cryptic", but anyway it is a perfectly "good" species: morphological distinctiveness is irrelevant for the general definition of species category (but of course it may be useful as a "marker" in recognition of species in particular cases, e.g. in case of allochronic or allopatric populations - see the final paragraphs of the attached paper). On the other hand, subspecies is a "morpho-geographical" category: a not isolated reproductively but morphologically significantly (a "rule of thumb" criterion is Amadon's 75% rule) distinctive allo- or para-patric [group of] population[-s]; thus, "cryptic" species, as being morphologically indistinctive, can only in exceptional, never or but extremely rarely realized in practice, situations show subspecific differentiation. Generally, the category of subspecies is very useful as largely generalized but highly informative illustration of patterns of geographic variability, in clarification of many ecological, evolutionary and/or palaeogeographic questions &c., but of course only if it is correctly interpreted and consistently applied!




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{Blacks and Indians would be considered a Cryptic Species and a Subspecies}.



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A Burst of Clues to South Asians’ Genetic Ancestry

September 5, 2019

https://www.theatlantic.com/science/archive/2019/09/indus-valley-civilization-dna-has-long-eluded-researchers/597481/

A tiny ear bone from more than 4,000 years ago is shaping the story of migration and heritage in India.

The climate of South Asia is not kind to ancient DNA. It is hot and it rains. In monsoon season, water seeps into ancient bones in the ground, degrading the old genetic material. So by the time archeologists and geneticists finally got DNA out of a tiny ear bone from a 4,000-plus-year-old skeleton, they had already tried dozens of samples—all from cemeteries of the mysterious Indus Valley civilization, all without any success.

The Indus Valley civilization, also known as the Harappan civilization, flourished 4,000 years ago in what is now India and Pakistan. It surpassed its contemporaries, Mesopotamia and ancient Egypt, in size. Its trade routes stretched thousands of miles. It had agriculture and planned cities and sewage systems. And then, it disappeared. “The Indus Valley civilization has been an enigma for South Asians. We read about it in our textbooks,” says Priya Moorjani, a computational biologist at the University of California at Berkeley. “The end of the civilization was quite mysterious.” No one alive today is sure who the people of the Indus Valley civilization were or where they went.

A pair of newly published papers use ancient DNA to shed light on the Indus Valley civilization and the entire history of people in South and Central Asia. The first study is a sweeping collection of 523 genomes—300 to 12,000 years old—from a region spanned by Iran, Russia, and India. By comparing the results with modern South Asians’ genomes, the study showed that South Asians today descended from a mix of local hunter-gatherers, Iranian-related groups, and steppe pastoralists who came by way of Central Asia. It’s the largest number of ancient genomes reported in a single paper, all made possible by an ancient DNA “factory” the geneticist David Reich has built at Harvard. (Moorjani completed her doctorate in Reich’s lab and is a co-author on this paper.)

The second study focuses on just a single genome from the Indus Valley civilization: I6113, a woman who died more than 4,000 years ago. Her skeleton was the only one—out of more than 100 samples the researchers tested from 10 different Indus Valley–civilization sites—that yielded ancient DNA, but even then it was contaminated and of poor quality. “We had to squeeze, squeeze, squeeze the sample really hard, more than we’ve done in any other sample we’ve ever tried,” says Reich, who is also a senior author of the second paper. The team ultimately tried to sequence DNA from I6113’s ear bone more than 100 times, each time yielding a tiny dribble of genetic data. That I6113 gets her own paper is a testament to both the technical difficulty of sequencing her DNA and the importance of the Indus Valley civilization. Even before publication, rumors were swirling in India about what the ancient DNA would show, and how it would play into the politics of the Hindu-nationalist ruling party.

What’s intriguing about I6113’s DNA is what she lacks: any of the steppe ancestry that is widespread in contemporary South Asians. Instead, she appeared to have a mix of Southeast Asian hunter-gatherer and Iranian-related ancestry.

The two studies piece together a history of how the people of the Indus Valley civilization are related to South Asians today. After the decline of the civilization 4,000 years ago, people with a genetic makeup similar to I6113 mixed with people of Southeast Asian hunter-gatherer ancestry to form what has been called Ancestral South Indians. From 4,000 to 3,000 years ago, other people descended from the Indus Valley civilization mixed with people of steppe-pastoralist ancestry, who likely brought horses and the Indo-European languages now spoken on the subcontinent, to form a group that has been called Ancestral North Indians. These two ancestral groups then mixed as well, giving rise to the great diversity of ethnic groups in South Asia. Go back far enough, and both sides trace to the Indus Valley civilization, which appears to be the single largest source of ancestry for modern South Asians.

The team studying I6113 noticed something intriguing about the Iranian-related portion of her ancestry, too. It appears to date to before the advent of farming in the Fertile Crescent. This suggests that farming did not, as many have thought, spread to South Asia through the migration of people from the Near East. It may have arisen independently in South Asia or spread through cultural contact.

Of course, this is a lot to rest on a single genome. “That would be like taking a single sample from Tokyo and trying to generalize about the whole ancestry of Japan,” Reich admits. But the team’s confidence in its results was bolstered when the researches found that I6113 was genetically similar to 11 people from the 523-genome paper who were buried not in South Asia, but in what is now Iran and Turkmenistan. These 11 people were also “outliers” in their own burial sites. The team thinks they may have been migrants or the children of migrants from the Indus Valley civilization. Archaeological evidence suggests people traveled between these regions as well.

The cities of the Indus Valley Civilization were cosmopolitan places, which also makes it harder to generalize from one genome. J. Mark Kenoyer, an anthropologist at the University of Wisconsin at Madison who was not an author of either study, cautions that only a small number of people who lived in these cities were buried in cemeteries—probably elites. The rest might have been cremated, or their bones simply left uncovered and thus scattered over time. “The cemeteries of the Indus civilization do not represent the people of the Indus civilization. They represent one community,” he says.

Still, more cemetery samples would be better than just one. The research team behind I6113 is trying to sequence more bones from the Indus Valley civilization. Vasant Shinde, an archeologist at Deccan College whose team excavated I6113, says the attempts to get ancient DNA from Indus Valley–civilization sites have been a years-long learning process. To prevent contamination with modern DNA, team members now wear gowns and masks even while excavating in the field. They do not reuse excavation instruments from burial to burial. Niraj Rai, a geneticist who was a visiting fellow in Reich’s lab, also set up an ancient-DNA lab at the Birbal Sahni Institute of Palaeosciences in Lucknow, India, where I6113’s DNA was extracted. “This is beginning,” Shinde says. “This is not the end.” He expects more ancient DNA to come.

In India, ancient DNA has generated intense interest, says Tony Joseph, the author of Early Indians: The Story of Our Ancestors and Where We Came From. He told me his book, published last December, is already in its seventh printing. After a preliminary version of the large Central and South Asian genomes study was posted on bioRxiv last March, it became the site’s most downloaded preprint of 2018. The preprint generated controversy, too, especially the finding that many Indians have ancestry from steppe pastoralists. Hindu nationalists, as Joseph has written, believe that Aryans—who originated in India and spread through Europe and Asia—are the source of Indian civilization. This is contradicted by ancient DNA that finds the population history in India itself contains far more mixing and migration. (Further complicating things, Nazis co-opted the term Aryans to mean something different, a master race of European origin.) A prominent MP even attacked Reich when the preprint came out, tweeting out an article titled, “There Are Lies, Damned Lies and (Harvard’s ‘Third’ Reich and Co’s) Statistics.” Reich, who has experienced how fraught talking about genetics and identity can be, acknowledged the political interest in his work, but declined to get into it.

Ancient DNA has captured the public imagination precisely because it promises an answer to questions like Where did we come from? and Who are we?—questions that also have deep political undercurrents. To sequence I6113’s DNA is to draw genetic connections between an ancient civilization and the people who live in the region today, to add fuel to arguments about who can lay claim to a cultural inheritance. All this, contained in a half-inch wisp of an ear bone.

 

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Genetics and archaeogenetics of South Asia

https://en.wikipedia.org/wiki/Genetics_and_archaeogenetics_of_South_Asia

Contents

    1 Overview
    2 mtDNA
        2.1 Macrohaplogroup M
        2.2 Macrohaplogroup R
            2.2.1 Haplogroup U
    3 Y chromosome
        3.1 Haplogroup H
        3.2 Haplogroup J2
        3.3 Haplogroup L
            3.3.1 India
            3.3.2 Pakistan
            3.3.3 Sri Lanka
        3.4 Haplogroup R1a1
            3.4.1 India
            3.4.2 Pakistan
            3.4.3 Sri Lanka
            3.4.4 Maldives
            3.4.5 Nepal
        3.5 Haplogroup R2
            3.5.1 India
            3.5.2 Pakistan
            3.5.3 Sri Lanka
            3.5.4 Maldives
            3.5.5 Nepal
        3.6 Haplogroup O2a (O-K18)
    4 Reconstructing South Asian population history
        4.1 mtDNA variation
        4.2 Y Chromosome variation
        4.3 Autosomal DNA variation
            4.3.1 AASI-ANI-ASI
            4.3.2 Genetic distance between caste groups and tribes
    5 See also
    6 Notes
    7 References
        7.1 Further reading
    8 Sources
    9 External links






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Who was here first? A new study explains the origins of ancient Indians

April 3, 2018

https://qz.com/india/1243436/aryan-migration-scientists-use-dna-to-explain-origins-of-ancient-indians/

 

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Rare Ancient DNA Provides Window Into a 5,000-Year-Old South Asian Civilization

September 5, 2019

The Indus Valley Civilization flourished alongside Mesopotamia and Egypt, but the early society remains shrouded in mystery

https://www.smithsonianmag.com/science-nature/rare-ancient-dna-south-asia-reveals-complexities-little-known-civilization-180973053/


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How ancient DNA may rewrite prehistory in India

30 December 2018

https://www.bbc.com/news/world-asia-india-46616574

New research using ancient DNA is rewriting prehistory in India - and shows that its civilisation is the result of multiple ancient migrations, writes Tony Joseph.

Who are the Indians? And where did they come from?

In the last few years, the debate over these questions has become more and more heated.

Hindu right-wingers believe the source of Indian civilisation are people who called themselves Aryans - a nomadic tribe of horse-riding, cattle-rearing warriors and herders who composed Hinduism's oldest religious texts, the Vedas.

The Aryans, they argue, originated from India and then spread across large parts of Asia and Europe, helping set up the family of Indo-European languages that Europeans and Indians still speak today.

As it happens, many 19th Century European ethnographers and, of course, most famously, Adolf Hitler, also considered Aryans the master race who had conquered Europe, although the German leader considered them to be of Nordic lineage.

When scholars use the term Aryan, it refers to a group of people who spoke Indo-European languages and called themselves Aryans. And that is how I have used it in this article. It does not refer to a race, as Hitler used it or as some in the Hindu right wing use it.

Many Indian scholars have questioned the "out of India" thesis, arguing that these Indo-European language speakers - or Aryans - were possibly just one of many streams of prehistoric migrants who arrived in India after the decline of an earlier civilisation. This was the Harappan (or Indus Valley) civilisation, which thrived in what is now north-western India and Pakistan around the same time as the Egyptians and Mesopotamians.

However, Hindu right-wingers believe the Harappan civilisation was also an Aryan or Vedic civilisation.

Tensions between the two groups backing these opposing theories have only increased in the last few years, especially since the Hindu nationalist Bharatiya Janata Party (BJP) came to power in India in 2014.

Into this long-running dispute has now stepped the relatively new discipline of population genetics, which has started using ancient DNA to figure out when people moved where. 

 

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Modern DNA reveals ancient origins of Indian population

May 8, 2017

Where did the earliest Indians come from?

The origins of the peoples of the Indian Subcontinent remains a much debated topic among scientists. But new research has offered some clarity on the matter.

https://www.upi.com/Science_News/2017/05/08/Modern-DNA-reveals-ancient-origins-of-Indian-population/6721494272565/

 

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Indian study of genetics of Andaman Islanders uncovers new human ancestor

 https://www.sott.net/article/323869-Indian-study-of-genetics-of-Andaman-Islanders-uncovers-new-human-ancestor


 A study published a few days ago in the journal Nature Genetics has found the presence of a third and a new ancestor to humans — a sibling of the Neanderthal and the Denisovan. The study compared the complete DNA sequences of the Jarawas and the Onges living in the Andaman Islands in the Bay of Bengal with the DNA sequences of Neanderthals and Denisovans, and they found some notable differences in the DNA sequences.

"In this study we have found in the DNA sequence of modern humans, specially in the Jarawa and Onge populations, fragments of DNA that belong neither to the Neanderthal nor the Denisovan nor even to most of the contemporary human groups," says Partha P. Majumder, one of the corresponding authors of the paper and Director of the National Institute of Biomedical Genomics in Kalyani, West Bengal.


 "Further statistical analysis of the DNA segments showed that the best explanation of the origin of these DNA fragments is that they belong to an unknown third human ancestor that is already extinct. The unknown human ancestor is like an evolutionary sibling of the Neanderthal and the Denisovan." 

 A small proportion of DNA from the unknown extinct hominin is found only in the population from South and Southeast Asia while it is absent from Europeans and East Asians. "That there is an ancestor of modern humans that was not discovered earlier is a major finding of our work," he says.

Though the remains of this extinct hominin have not been recovered yet, Dr. Majumder says the genome results provide definitive evidence that Homo heidelbergensis had given rise to multiple lineages, not just the Neanderthal and the Denisovan. The modern humans, Neanderthals and Denisovans all shared a common ancestor about 600,000 years ago.

Though the traditional approach is find fossils to conclusively prove the presence of a new ancestral lineage, thanks to genomics, scientists are today no longer completely dependent on fossils.

The whole genomes of 60 individuals drawn from a carefully sampled set of diverse ethnic groups of mainland India and 10 Jarawas and Onges were sequenced. In order to make the inferences more robust and enable comparisons, the genome data from other sources — 1000 Genomes study, Great Apes Genome Project, and 69 Genomes project of Complete Genomics — were also used in the joint statistical analysis.

The second major finding by the team was in ascertaining the reasons for the short stature of the Jarawas and Onges, and in finding out if it was because of their direct ancestral relationship to some population in Africa. The researchers identified 107 genes that have evolved under the impact of positive, advantageous natural selection. About 10 per cent (11 of 107) of these genes are involved in the determination of height. "What we found is that the short stature of the Jarawas and Onges is due to natural selection acting on genes that are known to determine height," says Dr. Majumder. 



----------------------------


New Study Shows Neanderthals Were Not Our Ancestors


Summary:
 
In the most recent and mathematically rigorous study to date determining whether Neanderthals contributed to the evolution of modern humans, a team of anthropologists examining the skulls of modern humans and Neanderthals as well as 11 existing species of non-human primates found strong evidence that Neanderthals differ so greatly from Homo sapiens as to constitute a different species.



 https://www.sciencedaily.com/releases/2004/01/040127085316.htm
 
 

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Near Eastern brachycephals; Syria, Armenia, and the Caucasus

https://www.theapricity.com/snpa/chapter-XII18.htm

 

-------------------------


Armenoid race

https://en.wikipedia.org/wiki/Armenoid_race



-------------------------

What did original Arabs look like


https://selfuni.wordpress.com/tag/what-did-original-arabs-look-like/



--------------------------



Profile of genetic disorders prevalent in northeast region of Cairo, Egypt

https://www.sciencedirect.com/science/article/pii/S1110863011000620

 


--------------------------

 

Some Polynesians Carry DNA of Ancient Native Americans

2020

https://www.nytimes.com/2020/07/08/science/polynesian-ancestry.html

 

--------------------------

 
Ancient DNA Yields Unprecedented Insights into Mysterious Chaco Civilization

February 22, 2017

https://www.scientificamerican.com/article/ancient-dna-yields-unprecedented-insights-into-mysterious-chaco-civilization/

 

--------------------------

 

No 'lost tribes' or aliens: what ancient DNA reveals about American prehistory

Nov 2017

New genetics research settles questions about the peoples of Newfoundland and Labrador – and helps highlight what genetics can’t tell us

https://www.theguardian.com/science/2017/nov/15/no-lost-tribes-or-aliens-what-ancient-dna-reveals-about-american-prehistory




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Y-DNA test reveals ‘Irish-American’ is actually Native American

https://www.abroadintheyard.com/y-dna-test-reveals-irish-american-is-actually-native-american/

Amateur genealogist Steve Woodall believed that his direct male-line ancestors, and carriers of the Woodall surname, descended from Irish stock.  But, despite years of research, he could not reach further back than his 3 x great-grandfather, William Wagner Woodall, born in 1818 in North Carolina.  To get past the dead end, Steve turned to DNA testing – and got an unexpected result.  He told KUHF Houston Public Radio, “We got the DNA test that says that it appears that we’re Native Americans and we’re like what? We’re what?“

Steve’s European appearance gave no hint of Native American heritage, yet Family Tree DNA confirmed his Y-DNA haplogroup as Q1a3a1.  This haplogroup is strictly associated with the indigenous peoples of the Americas and is defined by the genetic marker M3, which occurred on the Q lineage roughly 10-15 thousand years ago as the migration from Siberia into the Americas was in progress.  Steve is now searching for Y-DNA matches with other Q1a3a1 males through FTDNA and ysearch, to enable him to track his Native American lineage before William Wagner Woodall.  He has already discovered 4 other Woodalls whose markers match.

Steve has posted some fascinating details of William Wagner Woodall’s life (1818 – 1906) on geni.com.  William was a full-bloodied Cherokee Indian and possibly acquired the Woodall surname by adoption; he tended to be vague about his origins on official 19th century returns, as it was common for Native Americans at the time to deny their roots and blend in with white populations.  William would have been 12 years old when the US government passed the Indian Removal Act of 1830, a process of cultural transformation originally proposed by George Washington to open up land for white settlement.  This led to the infamous ‘Trail of Tears’ between 1831 and 1838, the forced relocation of almost 50,000 Native Americans from their homelands in the southeastern United States to the newly designated ‘Indian Territory’ west of the Mississippi.  Many Native Americans died from exposure, disease and starvation en route, including 4,000 of the 15,000 relocated Cherokee...



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Ancient DNA hints at the genetic lineage of today’s Native Americans

Wednesday, June 5, 2019

By studying ancient teeth and bones, researchers have come closer than ever to identifying a Native American ancestor, hailing from what’s now Siberia.

By the end of the last ice age, some 14,500 years ago (and possibly long before), humans had made their way into the Americas, traversing a land mass called Beringia that bridged what is now Siberia to Alaska. These early peoples eventually became indigenous Americans, including Alaska Natives, Canadian First Nations, and Native Americans.

But many of the details of these early migrations, of which there were multiple, have remained mostly unclear—including which of the many cultural groups that once populated ancient Siberia successfully crossed the Bering Sea.

Now, findings from two new studies published today in the journal Nature may provide long-awaited clues about the mysterious ancestors of these prehistoric peoples. Though both studies leverage the power of ancient DNA to enrich the human family tree, both also raise further questions about the complex migrations that ultimately yielded modern populations.

In the first study, a team of scientists led by Eske Willerslev, a geneticist at the University of Copenhagen, attempted to pinpoint a lineage in ancient Siberia with strong genetic links to Native Americans. The researchers sequenced genomes from 34 individuals that inhabited Siberia, Beringia, and Alaska between 600 and 31,600 years ago, and compared them to DNA from modern Native Americans. The nearest match was a woman the team calls Kolyma1, who lived in northeastern Siberia some 9,800 years ago. About two-thirds of her genome bears a remarkable similarity to those of living Native Americans, making her “the closest we have ever gotten to a Native American ancestor outside the Americas,” Willerslev told Michael Price at Science.

https://www.pbs.org/wgbh/nova/article/indigenous-americans-siberia/



--------------------------



Lost Native American Ancestor Revealed in Ancient Child’s DNA

Study of 11,500-year-old bones offer surprising clues about the origins of New World genetic diversity.

January 3, 2018

https://www.nationalgeographic.com/science/article/alaska-dna-ancient-beringia-genome

A baby girl who lived some 11,500 years ago survived for just six weeks in the harsh climate of central Alaska, but her brief life is providing a surprising and challenging wealth of information to modern researchers.

Her genome is the oldest-yet complete genetic profile of a New World human. But if that isn’t enough, her genes also reveal the existence of a previously unknown population of people who are related to—but older and genetically distinct from— modern Native Americans.

This new information helps sketch in more details about how, when, and where the ancestors of all Native Americans became a distinct group, and how they may have dispersed into and throughout the New World.

The baby’s DNA showed that she belonged to a population that was genetically separate from other native groups present elsewhere in the New World at the end of the Pleistocene. Ben Potter, the University of Alaska Fairbanks archaeologist who unearthed the remains at the Upward River Sun site in 2013 , named this new group “Ancient Beringians.”

The discovery of the baby’s bones, named Xach'itee'aanenh T'eede Gaay, or Sunrise Child-Girl in a local Athabascan language, was completely unexpected, as were the genetic results, Potter says.

Found in 2006 and accessible only by helicopter, the Upward River Sun site is located in the dense boreal forest of central Alaska’s Tanana River Valley. The encampment was buried under feet of sand and silt, an acidic environment that makes the survival of organic artifacts exceedingly rare. Potter previously excavated the cremated remains of a three-year-old child from a hearth pit in the encampment, and it was beneath this first burial that the six-week-old baby and a second, even younger infant were found.

A genomics team in Denmark, including University of Copenhagen geneticist Eske Willerslev, performed the sequencing work on the remains, comparing the child’s genome with the genes of 167 ancient and contemporary populations from around the world. The results appeared today in the journal Nature.


Oldest Human Skeleton in Americas Found in Underwater Cave

In a pitch black, 140-foot-deep underwater cave, three divers make a stunning 13,000-year-old discovery: the oldest complete human skeleton ever found in the Americas.

“We didn’t know this population even existed,” Potter says. “Now we know they were here for many thousands of years, and that they were really successful. How did they do it? How did they change? We now have examples of two genetic groups of people who were adapting to this very harsh landscape.”

The genetic analysis points towards a divergence of all ancient Native Americans from a single east Asian source population somewhere between 36,000 to 25,000 years ago—well before humans crossed into Beringia, an area that includes the land bridge connecting Siberia and Alaska at the end of the last ice age. That means that somewhere along the way, either in eastern Asia or in Beringia itself, a group of people became isolated from other east Asians for about 10,000 years, long enough to become a unique strain of humanity.

The girl’s genome also shows that the Beringians became genetically distinct from all other Native Americans around 20,000 years ago. But since humans in North America are not reliably documented before 14,600 years ago, how and where these two groups could have been separated long enough to become genetically distinct is still unclear.

The new study posits two new possibilities for how the separation could have happened.

The first is that the two groups became isolated while still in east Asia, and that they crossed the land bridge separately—perhaps at different times, or using different routes.


A second theory is that a single group moved out of Asia, then split into Beringians and ancient Native Americans once in Beringia. The Beringians lingered in the west and interior of Alaska, while the ancestors of modern Native Americans continued on south some time around 15,700 years ago.

“It’s less like a tree branching out and more like a delta of streams and rivers that intersect and then move apart,” says Miguel Vilar, lead scientist for National Geographic’s Genographic Project. “Twenty years ago, we thought the peopling of America seemed quite simple, but then it turns out to be more complicated than anyone thought.”

John Hoffecker, who studies the paleoecology of Beringia at the University of Colorado-Boulder, says there is still plenty of room for debate about the geographic locations of the ancestral splits. But the new study fits well with where the thinking has been heading for the last decade, he adds.

“We think there was a great deal more diversity in the original Native American populations than is apparent today, so this is consistent with a lot of other evidence,” Hoffecker says.

However, that same diversity—revealed through research on Native American cranial morphology and tooth structure—creates its own dilemma. How does a relatively small group of New World migrants, barricaded by a challenging climate with no access to fresh genetic material, evolve such a deep bank of differences from their east Asian ancestors? It certainly doesn’t happen over just 15,000 years, Hoffecker insists, referring to the estimated date of divergence of ancient Native Americans from Beringians.

“We’ve been getting these signals of early divergence for decades—the first mitochondrial work in the 1990s from Native Americans were coming up with estimates of 30, 35, even 40,000 years ago,” Hoffecker says. “They were being dismissed by everybody, myself included. Then people began to suspect there were two dates: one for divergence, and one for dispersal, and this study supports that.”

“Knowing about the Beringians really informs us as to how complex the process of human migration and adaptation was,” adds Potter. “It prompts the scientist in all of us to ask better questions, and to be in awe of our capacity as a species to come into such a harsh area and be very successful.”





--------------------------




Surprise as DNA reveals new group of Native Americans: the ancient Beringians

3 Jan 2018

Genetic analysis of a baby girl who died at the end of the last ice age shows she belonged to a previously unknown ancient group of Native Americans

https://www.theguardian.com/science/2018/jan/03/ancient-dna-reveals-previously-unknown-group-of-native-americans-ancient-beringians


--------------------------



Alaskan infant's DNA tells story of 'first Americans'

3 January 2018

https://www.bbc.com/news/science-environment-42555577




--------------------------


DNA tests stand on shaky ground to define Native American identity

May 09, 2019

https://www.genome.gov/news/news-release/DNA-tests-stand-on-shaky-ground-to-define-Native-American-identity

 

--------------------------

 

Arabian DNA Shows Route of Early Human Migration from Africa

October 21, 2021

https://greekreporter.com/2021/10/21/arabian-dna-africa/

 

--------------------------

 


SUBSPECIES, SEMISPECIES, SUPERSPECIES

2001

http://abacus.gene.ucl.ac.uk/jim/pap/Sub-semi.pdf


II. The subspecies today A. Modern views of subspecies,  semispecies, and superspecies The view of Darwin, Wallace, Rensch and Mayr that geographic replacement forms, subspecies, semispecies, which form a continuum with species, were in fact incipient species, has few critics today. Most geographic replacement species or “semispecies” which do not intergrade when they meet must indeed have evolved from previously interbreeding subspecies. Modern genetic data has done nothing to cast doubt on this idea.   However, taxonomists were now required to describe subspecies, which has never been seen as a particularly honourable or worthwhile activity in comparison with describing species, especially recently. A strong attack on the subspecies was mounted by Wilson & Brown (1953). Both were systematists working on ants, a group particularly riddled with poorly conceived trinomials at the time. Wilson and Brown argued that subspecies rarely, if ever, could be justified on the basis of multiple characters, and that therefore they were not “real taxa”. The only “real taxa” were species, which in a sense were self-defining because interbreeding prevented divergent genes from flowing from one species to another. Subspecies which interbred at their boundaries, on the other hand, were not so endowed, so that genes and morphological characters could flow between them. Good examples were put forward of subspecies which undoubtedly would be hard to justify on multiple character grounds. This single paper was enormously influential on systematics in the USA, and generations of systematists trained at Harvard and Cornell, where Wilson and Brown worked, and their own many intellectual descendants, and their students’ students in turn, have eschewed the practice of naming subspecies.   Through genetic studies we now know, however, that many subspecies separated by hybrid zones differ at multiple morphological, behavioural, and genetic characters (Barton & Hewitt 1985). For instance, the toad Bombina bombina meets its relative Bombina variegata across a broad front in Europe, and differs strongly in call, morphology, skin thickness, the sizes of water bodies used, and egg size, as well as in mitochondrial DNA and protein sequence. Their levels of differentiation suggest that the Bombina have evolved separately for many millions of years. (The two forms hybridize freely in the contact zone – although the hybrids can be shown to suffer some inviability – and so should be classified as members of the same polytypic species under the polytypic or biological species concept, but it has always seemed natural to place such well-defined forms in separate species in spite of the fact they have not truly “speciated”). This situation of multiple character changes has now been shown to be true across very many examples of hybrid zones, and gene flow can be shown to be almost completely blocked by hybrid zones such as these, in spite of abundant hybridization. Thus, while many named subspecies undoubtedly merited Wilson & Brown’s scorn, genetic evidence shows that there are plenty of local replacement forms which hybridize at their boundaries but which do form “real” identifiable taxa, and are valid subspecies under the Wilson & Brown criteria.



--------------------------------------------------------------------------------


 Monotypic taxon

https://en.wikipedia.org/wiki/Monotypic_taxon


In biology, a monotypic taxon is a taxonomic group (taxon) that contains only one immediately subordinate taxon.

A monotypic species is one that does not include subspecies or smaller, infraspecific taxa. In the case of genera, the term "unispecific" or "monospecific" is sometimes preferred.

In botanical nomenclature, a monotypic genus is a genus in the special case where a genus and a single species are simultaneously described.

In contrast an oligotypic taxon contains more than one but only a very few subordinate taxa.



--------------------------------------------------------------------------------



 Ecotype

https://en.wikipedia.org/wiki/Ecotype

In evolutionary ecology, an ecotype,[note 1] sometimes called ecospecies, describes a genetically distinct geographic variety, population or race within a species, which is genotypically adapted to specific environmental conditions.

Typically, though ecotypes exhibit phenotypic differences (such as in morphology or physiology) stemming from environmental heterogeneity, they are capable of interbreeding with other geographically adjacent ecotypes without loss of fertility or vigor.

Arabis fecunda, a herb endemic to some calcareous soils of Montana, United States, can be divided into two ecotypes. The one "low elevation" group lives near the ground in an arid, warm environment and has thus developed a significantly greater tolerance against drought than the "high elevation" group. The two ecotypes are separated by a horizontal distance of about 100 km.



--------------------------------------------------------------------------------


Subspecies, Semispecies, Superspecies. A Brief History of Subspecific Taxonomy Variation Below the Level of Species.

 2013


 https://www.researchgate.net/publication/276059079_Subspecies_Semispecies_Superspecies_A_Brief_History_of_Subspecific_Taxonomy_Variation_Below_the_Level_of_Species_2013




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The Superspecies Concept


 01 September 1966

Abstract

The concept of “superspecies,” as applied to a monophyletic group of allopatric or nearly allopatric taxa that are known or believed to have evolved to the species level, was introduced to the literature by E. Mayr and by B. Rensch. The concept is of great utility in many studies of evolution and zoogeography. The use of superspecies has been somewhat retarded by the absence of any formalized notation for them in Linnaean nomenclature. It is here proposed that brackets (= square parentheses) enclose the first named species of a superspecies: thus, superspecies Bubo [bubo], or Bubo [bubo] virginianus to indicate that the species virginianus is a member of the superspecies Bubo [bubo]. The term “allospecies” is suggested for the species comprising a superspecies. The use of parentheses ( ) should be restricted to indicating “semispecies,” that is, forms believed to be subspecies, but approaching, or possibly of, species status, e.g., Accipiter (gentilis) atricapillus.


https://academic.oup.com/sysbio/article-abstract/15/3/245/1704294?redirectedFrom=PDF



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The central role of Darwinism in the Holocaust

2017

https://creation.com/images/pdfs/tj/j31_3/j31_3_103-111.pdf




----------------------------------------



The Horrifying American Roots of Nazi Eugenics

https://historynewsnetwork.org/article/1796



----------------------------------------



{Eugenics can be used for good or it can be used for bad.

I think that we should have a majority white race and see to it that the brown race does not overpopulate and burn the rainforests down, this includes poaching too many animals like they are doing}.


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Analytical approaches to subspecies delimitation with genetic data

June 2017

https://swfsc.noaa.gov/publications/CR/2017/2017Martien.pdf



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 Subspecies

https://en.wikipedia.org/wiki/Subspecies


In biological classification, the term subspecies refers to one of two or more populations of a species living in different subdivisions of the species' range and varying from one another by morphological characteristics. A single subspecies cannot be recognized independently: a species is either recognized as having no subspecies at all or at least two, including any that are extinct. The term may be abbreviated to subsp. or ssp. The plural is the same as the singular: subspecies.

In zoology, under the International Code of Zoological Nomenclature, the subspecies is the only taxonomic rank below that of species that can receive a name. In botany and mycology, under the International Code of Nomenclature for algae, fungi, and plants, other infraspecific ranks, such as variety, may be named. In bacteriology and virology, under standard bacterial nomenclature and virus nomenclature, there are recommendations but not strict requirements for recognizing other important infraspecific ranks.

A taxonomist decides whether to recognize a subspecies. A common criterion for recognizing two distinct populations as subspecies rather than full species is the ability of them to interbreed without a fitness penalty. In the wild, subspecies do not interbreed due to geographic isolation or sexual selection. The differences between subspecies are usually less distinct than the differences between species.



------------------------------------------------------------------------------------



The Subspecies Concept and Its Taxonomic Application

Aug, 2019

http://hydrodictyon.eeb.uconn.edu/eebedia/images/3/3c/WilsonBrown1953.pdf



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Are human races cladistic subspecies?

2015

https://philarchive.org/archive/MNCAHR

Introduction


Much of the consensus that race is biologically unreal follows Richard Lewontin’s (1972) oft-cited claim  that  racial  classification  in  humans  is  biologically  meaningless  because  there  is  more  genetic variation within so-called ‘races’ than between so-called ‘races’. Since significant genetic difference between races is often part of the biological concept of race, Lewontin argues that the actual genetic homogeneity across races means that the human species is too genetically similar to be divided into discrete gene pools that might qualify as ‘races’. Andreasen  (1998,  2000,  2004,  2005,  2007)  proposes  that  contrary  to  popular  scientific  belief,  races  are  biologically  real—it  is  just  that  we  are  wrong  about  them.  She  argues  that  where theorists like Lewontin are incorrect in their analysis of human race is by assuming that similarity  should  be  the  basis  of  ‘an  objective  classification  scheme  in  systematic  biology’  (Andreasen  2000:  p.  S657).  These  theorists  have  not  considered  a  genealogical  definition  of  human races as cladistic subspecies (p. S657). Andreasen contends that human races, as cladistic subspecies,  are  biologically  real  and  that  cladistic  subspecies  are  suitable  as  candidates  of  the  human race...



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Analytical approaches to subspecies delimitation with genetic data

https://swfsc.noaa.gov/publications/CR/2017/2017Martien.pdf




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Cougar Evolution and Subspecies

https://www.felineworlds.com/cougar-evolution-and-subspecies/


Many experts believe that the Cougar moved across the Bering land bridge approximately 8.5 million years ago. Studies of genetic materials show that the Cougar is very closely related genetically to the Cheetah. There is still more than we need to study in order to understand all that has taken place for the Cougar over millions of years. Why were they able to survive when so many other wild cats seem to be at the brink of extinction?

It was once believed that there were 32 subspecies in the world of the Cougar. However, the scientific take on this was all changed after DNA testing became the standard practice. Today we have them identified as 6 subspecies. They include the Argentine Cougar, Costa Rican Cougar, Eastern South American Cougar, North American Cougar, Northern South American Cougar, and Southern South American Puma.

As you can tell from the names, these Cougars are basically classified due to the regions where they live. What is interesting is that at times there will be one captured and it is extremely long distances from home. It isn’t known if these Cougars migrated for food and habitat or if they were moved by humans.



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7 - Recognition of subspecies status mediated by androgen-binding protein (ABP) in the evolution of incipient reinforcement on the European house mouse hybrid zone

August 2012

https://www.cambridge.org/core/books/evolution-of-the-house-mouse/recognition-of-subspecies-status-mediated-by-androgenbinding-protein-abp-in-the-evolution-of-incipient-reinforcement-on-the-european-house-mouse-hybrid-zone/70DB0E1E598D129714AD4264D459C91B



-------------------------



Tiger Evolution Study Reveals Genetic Evidence for Six Subspecies

10/25/18

https://www.newsweek.com/tiger-evolution-study-reveals-genetic-evidence-six-subspecie-1187353



------------------------



How Old Are Subspecies? A Tiger's Eye-View of Human Evolution


https://www.jstor.org/stable/40386954?seq=1



------------------------------------------------------------------------


 Quagga



The quagga (Equus quagga quagga) was a subspecies of plains zebra that lived in South Africa until becoming extinct late in the 19th century. It was long thought to be a distinct species, but early genetic studies have supported it being a subspecies of plains zebra. A more recent study suggested that it was merely the southernmost cline or ecotype of the species.









 https://en.wikipedia.org/wiki/Quagga


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Genomic islands of differentiation between house mouse subspecies

https://genome.cshlp.org/content/16/6/730.full



Abstract

Understanding the genes that contribute to reproductive isolation is essential to understanding speciation, but isolating such genes has proven very difficult. In this study I apply a multilocus test statistic to >10,000 SNP markers assayed in wild-derived inbred strains of house mice to identify genomic regions of elevated differentiation between two subspecies of house mice, Mus musculus musculus and M. m. domesticus. Differentiation was high through ∼90% of the X chromosome. In addition, eight regions of high differentiation were identified on the autosomes, totaling 7.5% of the autosomal genome. Regions of high differentiation were confirmed by direct sequencing of samples collected from the wild. Some regions of elevated differentiation have an overrepresentation of genes with host–pathogen interactions and olfaction. The most strongly differentiated region on the X has previously been shown to fail to introgress across a hybrid zone between the two subspecies. This survey indicates autosomal regions that should also be examined for differential introgression across the hybrid zone, as containing potential genes causing hybrid unfitness.







Figure 2.
Signed ln-transformed P-values from a χ2 analysis of a sliding window plotted against chromosomal position (midpoint of a sliding window). Positive values on the y-axis indicate a deficiency in the number of fixed differences between the subspecies while negative values indicate more fixed differences than expected. Sliding windows consist of 60 SNPs moved for five SNP each step. (Dashed line) Significance level for a surplus of fixed differences among subspecies, (arrows) regions of significantly elevated differentiation, (short horizontal gray bars) regions that were chosen for direct sequencing of independent samples of M. m. musculus and M. m. domesticus. Only chromosomes where significant differentiation was found are shown. Note that the y-axis of the X chromosome differs from those of the autosomes because of the overall much higher differentiation of the X. Base positions on the x-axis need to be multiplied by 10.




----------------------------



Contrasting evolution of expression differences in the testis between species and subspecies of the house mouse.

11 Oct 2006

https://europepmc.org/article/pmc/pmc1716265



---------------------------



Molecular Evolution of Cytochrome b of Subterranean Mole Rats, Spalax ehrenbergi Superspecies, in Israel

August 1999

https://link.springer.com/article/10.1007%2FPL00006544



---------------------------



Haptoglobin DNA polymorphism in subterranean mole rats of the Spalax ehrenbergi superspecies in Israel



https://www.nature.com/articles/hdy198911




------------------------------------------------------------------------



Natural epigenetic variation within and among six subspecies of the house sparrow, Passer domesticus

2017


https://jeb.biologists.org/content/jexbio/220/21/4016.full.pdf



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  Black squirrel 'super' species? No, just a darker shade of grey

Aug 13, 2019

Black squirrel result of interbreeding between grey and fox squirrels – and they both carry virus

https://www.theguardian.com/environment/2019/aug/13/black-squirrel-super-species-no-just-a-darker-shade-of-grey



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Geospecies and Superspecies in the African Primate Fauna

1 May 2006


https://bioone.org/journals/primate-conservation/volume-2006/issue-20/0898-6207.20.1.75/Geospecies-and-Superspecies-in-the-African-Primate-Fauna/10.1896/0898-6207.20.1.75.full



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 THE SUPERSPECIES DROSOPHILA PAULISTORUM

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300595/


-------------------------------------------------------------------


 Plant roots evolved at least twice, and step by step

Aug 23 2018

https://www.theguardian.com/science/2018/aug/23/lost-worlds-revisited-the-hidden-life-of-plant-roots












                                   (Exceptional cellular preservation of a meristem).



------------------------------------------------------

------------------------------------------------------



One of Darwin's evolution theories finally proved

March 17, 2020

https://www.sciencedaily.com/releases/2020/03/200317215626.htm


Scientists have proved one of Charles Darwin's theories of evolution for the first time -- nearly 140 years after his death.

Laura van Holstein, a PhD student in Biological Anthropology at St John's College, University of Cambridge, and lead author of the research published today (March 18) in Proceedings of the Royal Society, discovered mammal subspecies play a more important role in evolution than previously thought.

Her research could now be used to predict which species conservationists should focus on protecting to stop them becoming endangered or extinct.

A species is a group of animals that can interbreed freely amongst themselves. Some species contain subspecies -- populations within a species that differ from each other by having different physical traits and their own breeding ranges. Northern giraffes have three subspecies that usually live in different locations to each other and red foxes have the most subspecies -- 45 known varieties -- spread all over the world.



----------------------------



 Cassowary

https://en.wikipedia.org/wiki/Cassowary




Cassowaries (/ˈkésəwɛəri/), genus Casuarius, are ratites (flightless birds without a keel on their sternum bone) that are native to the tropical forests of New Guinea (Papua New Guinea and Indonesia), East Nusa Tenggara, the Maluku Islands, and northeastern Australia.

There are three extant species. The most common of these, the southern cassowary, is the third-tallest and second-heaviest living bird, smaller only than the ostrich and emu.

Cassowaries feed mainly on fruit, although all species are truly omnivorous and will take a range of other plant food, including shoots and grass seeds, in addition to fungi, invertebrates, and small vertebrates. Cassowaries are very wary of humans, but if provoked they are capable of inflicting serious injuries, including fatal, to both dogs and people. It has often been labeled "the world's most dangerous bird".


Cassowaries (from Malay kasuari) are part of the ratite group, which also includes the emu, rheas, ostriches, and kiwi, as well as the extinct moas and elephant birds. Three extant species are recognised, and one extinct:









Most authorities consider the taxonomic classification above to be monotypic, however, several subspecies of each have been described, and some of them have even been suggested as separate species, e.g., C. (b) papuanus. The taxonomic name C. (b) papuanus also may be in need of revision to Casuarius (bennetti) westermanni. Validation of these subspecies has proven difficult due to individual variations, age-related variations, the scarcity of specimens, the stability of specimens (the bright skin of the head and neck—the basis of describing several subspecies—fades in specimens), and the practice of trading live cassowaries for thousands of years, some of which are likely to have escaped or deliberately introduced to regions away from their origin.



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 Cassowary kick


https://www.youtube.com/results?search_query=cassowary+kick


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 Cassowary attacks

http://www.amazingaustralia.com.au/animals/cassowary-attacks.htm










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A new approach to understanding subspecies can boost conservation

February 2, 2017

https://theconversation.com/a-new-approach-to-understanding-subspecies-can-boost-conservation-68364











(A new understanding of subspecies, such as Reichenow’s Helmeted Guineafowl, can help conserve the birds).

Earth is home to an estimated 1 trillion species. To date, only about 1.2 million have been identified and described scientifically. There’s good reason to increase this number. Each species could offer an adaptive, evolutionary solution to the many challenges presented by changing landscapes.

Biological species are often comprised of geographically distinct entities. These are known as subspecies, races or management units.

Taxonomists and phylogeographers armed with this information ought to be able to identify those species with multiple evolutionary “solutions” in progress. These “solutions” should then be catered for to ensure the relevant species can be effectively conserved.

But this approach hasn’t been particularly successful, as the story of one giraffe species shows.

Giraffa camelopardalis has traditionally been partitioned into 11 subspecies. New research suggests it actually comprises only four morpho-genetic “entities” within it that warrant conservation action.

All four should be elevated to full species status. Why? To greatly simplify the strategy that’s needed for effective giraffe conservation.

A similar approach could help in developing meaningful conservation plans for many other species.




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Helmeted guineafowl


https://en.wikipedia.org/wiki/Helmeted_guineafowl


Taxonomy

The likely extinct subspecies N. m. sabyi of Morocco

In the early days of the European colonisation of North America, the native wild turkey (Meleagris gallopavo) was confused with this species. The word meleagris, Greek for guineafowl, is also shared in the scientific names of the two species, though for the guineafowl it is the species name, whereas for the turkey, it is the name of the genus and (in inflected form) the family.












Subspecies

There are nine recognised subspecies:

    N. m. coronata (Gurney, 1868) – Gurney's helmeted guineafowl – Type locality restricted to Uitenhage. Occurs in eastern and central South Africa and Western Swaziland.
    N. m. galeatus (Pallas, 1767) – West African guineafowl – western Africa to southern Chad, central Zaire, and northern Angola
    N. m. marungensis (Schalow, 1884) – Marungu helmeted guineafowl – south Congo Basin to western Angola and Zambia
    N. m. meleagris (Linnaeus, 1758) – Saharan helmeted guineafowl – eastern Chad to Ethiopia, northern Zaire, Uganda and northern Kenya
    N. m. mitrata (Pallas, 1764) – tufted guineafowl – Terra Typica "Madagascar" (introduced or erroneous). Occurs in Tanzania to Zambia, Botswana, northern South Africa, Eastern Swaziland and Mozambique.
    N. m. damarensis (Roberts, 1917) – Damara helmeted guineafowl – Terra Typica: Windhoek. Occurs from arid southern Angola to northern Namibia and Botswana north of 26°S[3]
    N. m. reichenowi (Ogilvie-Grant, 1894) – Reichenow's helmeted guineafowl – Kenya and central Tanzania
    N. m. sabyi (Hartert, 1919) – Saby's helmeted guineafowl – northwestern Morocco
    N. m. somaliensis (Neumann, 1899) – Somali tufted guineafowl – northeastern Ethiopia and Somalia



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Mitochondrial phylogenetics of the goshawk Accipiter [gentilis] superspecies


April 2019


https://onlinelibrary.wiley.com/doi/full/10.1111/jzs.12285

INTRODUCTION

Birds are among the best‐studied groups of animals, and our knowledge on their diversity, taxonomy, and phylogenetic relationships has steadily been growing. Although the Biological Species Concept as advertised by Ernst Mayr has not been universally applied in avian taxonomy (Sangster, 2014), its emphasis on polytypic species has probably contributed to the large number of described bird subspecies. To also appreciate the existence of very closely related groups of species, the superspecies concept was introduced. Ultimately going back to German terminology by Kleinschmidt and Rensch from the early 20th century, it was Mayr (1931) who introduced the term superspecies, translated from Rensch's Artenkreis, or circle of species, for a group of closely related species (Mallet, 2001). The component taxa of a superspecies were called semispecies by Mayr by which he meant “good,” but very similar species. In accordance with its linguistic connotation (semi‐meaning half), Amadon (1966), like Mayr (1931) specifically in an ornithological context, suggested to use the term semispecies for borderline cases between subspecies and full species and to refer to the “good” species within superspecies as allospecies. This terminology has been implemented, in a modified way, in the taxonomic guidelines of the British Ornithologists’ Union (BOU; Helbig, Knox, Parkin, Sangster, & Collinson, 2002). Superspecies here are monophyletic groups of allo‐ and semispecies that are less differentiated from one another than closely related species usually are. Allospecies are allopatric, while semispecies are connected by a stable hybrid zone. The BOU has also adopted Amadon's (1966) nomenclature according to which the superspecies’ [middle] names are denoted with square brackets. The BOU explicitly implemented the superspecies concept within the framework of species as lineages, as Helbig et al. (2002) mention the Evolutionary and the General Lineage Species Concepts, and it is meant to be applied to cases where the independence of lineages (“good” species) cannot be judged with confidence. In other words, it is an addition to our taxonomic arsenal to acknowledge the different levels of independence among phylogenetic lineages at and around the species level.









Figure 1

Geographical distribution of the Accipiter [gentilis] superspecies. Subspecies of A. gentilis according to del Hoyo and Collar (2014) as well as A. melanoleucus, A. henstii, and A. meyerianus are indicated by coloration. Additionally, formerly recognized A. g. caucasicus and A. g. khamensis are included. Filled areas represent all‐year‐round occurrence; hatched areas indicate temporary winter migration. Illustrations of A. gentilis apache, A. melanoleucus, and A. meyerianus are by David Mead; the copyright is held by Bloomsbury Publishing Plc, taken from Ferguson‐Lees and Christie (2001) Raptors of the World, London: Christopher Helm and A & C Black Ltd. Illustration of A. henstii is reproduced by permission of Lynx Edicions. Illustration of A. gentilis atricapillus is by Louis Agassiz Fuertes (under public domain)



-----------------------------


Evolutionary diversification of the limb skeleton in crested newts (Triturus cristatus superspecies, Caudata, Salamandridae)

2008

http://www.sekj.org/PDF/anz45-free/anz45-527.pdf



------------------------------



Evolutionary and paleogeographical effects on the distribution of the Triturus cristatus superspecies in the central Balkans

1997


https://brill.com/view/journals/amre/18/4/article-p321_1.xml?language=en


-------------------------------


Unraveling the rapid radiation of crested newts (Triturus cristatus superspecies) using complete mitogenomic sequences


14 June 2011


https://bmcevolbiol.biomedcentral.com/articles/10.1186/1471-2148-11-162


Abstract

Background

The rapid radiation of crested newts (Triturus cristatus superspecies) comprises four morphotypes: 1) the T. karelinii group, 2) T. carnifex - T. macedonicus, 3) T. cristatus and 4) T. dobrogicus. These vary in body build and the number of rib-bearing pre-sacral vertebrae (NRBV). The phylogenetic relationships of the morphotypes have not yet been settled, despite several previous attempts, employing a variety of molecular markers. We here resolve the crested newt phylogeny by using complete mitochondrial genome sequences.

Conclusions

We argue that the Bayesian full mitochondrial DNA phylogeny is superior to previous attempts aiming to recover the crested newt species tree. Furthermore, our new phylogeny involves a maximally parsimonious interpretation of NRBV evolution. Calibrating the phylogeny allows us to evaluate potential drivers for crested newt cladogenesis. The split between the T. karelinii group and the three other morphotypes, at ca. 10.4 Ma, is associated with the separation of the Balkan and Anatolian landmasses (12-9 Ma). No currently known vicariant events can be ascribed to the other two splits, first at ca. 9.3 Ma, separating T. carnifex - T. macedonicus, and second at ca. 8.8 Ma, splitting T. cristatus and T. dobrogicus. The crested newt morphotypes differ in the duration of their annual aquatic period. We speculate on the role that this ecological differentiation could have played during speciation.


--------------------------------




{White people are a superspecies, blacks would be considered a subspecies. Blacks would be defined as a subspecies because they have unknown DNA lineage in their blood. Look at how Whites have more genetic variation, while many blacks and Orientals have very bland features}.



--------------------------------


 Who were the ghost people of Africa? DNA reveals ancient Africans bred with new unknown race of humans just 50,000 years ago

 13 February 2020

    The researchers studied the genetic material of 405 people from West Africa
    They discovered mystery genetic material, which they have termed 'ghost DNA'
    It suggests that humans mixed with an unknown group about 50,000 years ago


https://www.dailymail.co.uk/sciencetech/article-7997861/New-study-shows-ghost-DNA-modern-day-population-west-Africa.html


-------------------------------- 

 
The 'Ghosts' of 2 Unknown Extinct Human Species Have Been Found in Modern DNA

17 JULY 2019

https://www.sciencealert.com/two-unknown-species-of-ancient-extinct-hominids-have-been-identified-in-modern-dna

 

--------------------------------

 

 Aboriginal Australians, Pacific Islanders carry DNA of unknown human species, research analysis suggests

 
October 2016

https://www.abc.net.au/news/2016-10-26/dna-of-extinct-human-species-pacific-islanders-analysis-suggests/7968950

 

--------------------------------


Subspecies, Semispecies, Superspecies

December 2007

https://www.researchgate.net/publication/239560887_Subspecies_Semispecies_Superspecies


--------------------------------



 The Neotropical Drosophila paulistorum Species Complex, a Classic Case of Speciation in statu nascendi

December 2, 2010


Abstract

The neotropical Drosophila paulistorum superspecies, consisting of at least six geographically overlapping but reproductively isolated semispecies, has been the object of extensive research since at least 1955, when it was initially trapped mid-evolution in flagrant statu nascendi. In this classic system females express strong premating isolation patterns against mates belonging to any other semispecies, and yet uncharacterized microbial reproductive tract symbionts were described triggering hybrid inviability and male sterility. Based on theoretical models and limited experimental data, prime candidates fostering symbiont-driven speciation in arthropods are intracellular bacteria belonging to the genus Wolbachia. They are maternally inherited symbionts of many arthropods capable of manipulating host reproductive biology for their own benefits. However, it is an ongoing debate as to whether or not reproductive symbionts are capable of driving host speciation in nature and if so, to what extent. Here we have reevaluated this classic case of infectious speciation by means of present day molecular approaches and artificial symbiont depletion experiments. We have isolated the α-proteobacteria Wolbachia as the maternally transmitted core endosymbionts of all D. paulistorum semispecies that have coevolved towards obligate mutualism with their respective native hosts. In hybrids, however, these mutualists transform into pathogens by overreplication causing embryonic inviability and male sterility. We show that experimental reduction in native Wolbachia titer causes alterations in sex ratio, fecundity, and mate discrimination. Our results indicate that formerly designated Mycoplasma-like organisms are most likely Wolbachia that have evolved by becoming essential mutualistic symbionts in their respective natural hosts; they have the potential to trigger pre- and postmating isolation. Furthermore, in light of our new findings, we revisit the concept of infectious speciation and discuss potential mechanisms that can restrict or promote symbiont-induced speciation at post- and prezygotic levels in nature and under artificial laboratory conditions.



The first case in literature suggesting that microbial reproductive parasites can play a pivotal role in driving host-speciation dates back to the late 1960s when Ehrman and coworkers discovered endosymbionts that trigger incipient speciation via hybrid inviability and male sterility in a neotropical Drosophila group species. The D. paulistorum species complex comprises at least six semispecies showing pronounced sexual isolation; matings between these semispecies succeed significantly less frequently than do those within a semispecies. These are: Amazonian (AM), Andean-Brazilian (AB), Centroamerican (CA), Interior (IN), Orinocan (OR), and Transitional (TR) semispecies. The primary extrinsic mechanism differentiating the D. paulistorum semispecies is geographic isolation, albeit incompletely because of consistently overlapping distributions. Three intrinsic isolation mechanisms are operative here - sexual isolation via behavior and hybrid male sterility both in reciprocal crosses. In addition to hybrid male sterility, abnormal pole cell development in early F1 hybrid embryos cause considerable high hybrid inviability; depicted in Figure 1. Since mortality takes place during early stages of embryogenesis,  and occurs at high frequencies in all hybrids derived from reciprocal matings between the six D. paulistorum semispecies, this phenotype can be best described as bidirectional cytoplasmic incompatibility, initially described by Laven in the Culex pipiens species complex













Figure 1. Schematic presentation of incipient speciation among D. paulistorum semispecies.



https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1001214




--------------------------------




The difference between a species and a subspecies – according to science

 July 25, 2019

https://www.zmescience.com/other/feature-post/difference-species-subspecies/







(Hartebeest subspecies: Bubal hartebeest (center); (clockwise from top-left corner) red hartebeest, Lelwel hartebeest, Swayne’s hartebeest, western hartebeest, Neumann’s hartebeest, Lichtenstein’s hartebeest, Coke’s hartebeest and Tora hartebeest, from Great and Small Game of Africa).



----------------------------------------------------



On the evolution of subspecies, as demonstrated by the alternation of variability existing in the subspecies of the genus Erebia (Lepidoptera)


04 May 2011

https://academic.oup.com/zoolinnean/article-abstract/40/271/305/2680114?redirectedFrom=PDF



----------------------------------------------------



Taxonomic assessment of two pygopodoid gecko subspecies from Western Australia

08 Jan 2020

https://brill.com/view/journals/ijee/aop/article-10.1163-22244662-20191078/article-10.1163-22244662-20191078.xml?language=en




------------------------------------------------------




Discovering a ring species

https://evolution.berkeley.edu/evolibrary/article/_0_0/devitt_02













Ensatina's basic story was laid out by Robert Stebbins 30 years before Tom was born in 1977. Based on the ring-like distribution of the different forms, Robert had proposed that the species started off in Northern California and Oregon and then spread south along both sides of the Central Valley, which was too dry and hot for salamanders.

According to Robert's hypothesis, as the pioneering populations moved south, they evolved into several subspecies with new color patterns and adaptations for living in different environments. By the time they met again in Southern California as the subspecies eschscholtzii and klauberi, he argued, they had each evolved so much that they no longer interbred — even though the subspecies blended into one another around the rest of the ring. Since species are often defined by their inability to interbreed with other species, Ensatina seemed to represent the whole process of speciation — all the gradual changes that accumulate in two lineages and that wind up making them incompatible with one another.


Of course, since this all would have happened millions of years ago, Robert wasn't around to observe any of it. He based his ideas on the morphology, or body form, of the subspecies — in this case, their color patterns. First, neighboring subspecies were more similar to one another than to those across the ring and seemed to blend into one another. From this, he hypothesized that Ensatina represented a ring species. Robert also noticed that the northern coastal form, called picta, had a pattern of colors that seemed to encompass the other subspecies. It was easy to imagine how the more specialized southern forms could have evolved from picta. Based on this, Robert hypothesized that the two southward-moving Ensatina lineages had both emerged from picta's immediate ancestors.



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Ancestry of An Isolated Subspecies of Salamander, Ambystoma tigrinum stebbinsi Lowe: the Evolutionary Significance of Hybridization

1995

https://www.sciencedirect.com/science/article/abs/pii/S1055790385710196


Abstract

Most phylogenetic systematists assume speciation results in dichotomously branching phylogenies. Hybridization that gives rise to a new Lineage can produce character homoplasy that might obscure a species′ true history. We report the results of a restriction-enzyme analysis of mitochondrial DNA (mtDNA) variation in three tiger salamander subspecies (Ambystoma tigrinum mavortium, Ambystoma tigrinum nebulosum, and Ambystoma tigrinum stebbinsi) and compare the results to studies of morphological and allozymic variation in these taxa. Allozymically, A. t. mavortium and A. t. nebulosum share most of their genomes (although each has several unique alleles), yet color pattern and mtDNA haplotypes are distinct. Color pattern and allozyme data suggest that A. t. stebbinsi shares a common ancestor with A. t. mavortium, while the A. t. stebbinsi mtDNA haplotype is derived from an A. t. nebulosum haplotype. Thus, our data suggest that A. t. stebbinsi originated through hybridization between A. t. mavortium and A. t. nebulosum. That hybridization can produce recognizably distinct evolutionary entities has long been recognized for plants, but the evolutionary significance of hybridization in animals should be examined more closely. Conservation agencies must recognize that hybrids and hybrid tars are not necessarily evolutionary "mistakes," and they might have significant importance in the production of natural biodiversity.



------------------------------------------------------



 Ebolavirus


https://en.wikipedia.org/wiki/Ebolavirus


Genus organization and common names





The genus Ebolavirus has been organized into five species; however, the nomenclature has proven somewhat controversial, with many authors continuing to use common names rather than species names when referring to these viruses. In particular, the generic term "Ebola virus" is widely used to refer specifically to members of the species Zaire ebolavirus. Consequently, in 2010, a group of researchers recommended that the name "Ebola virus" be adopted for a subclassification[note 1] within the species Zaire ebolavirus and that similar common names be formally adopted for other Ebolavirus species. In 2011, the International Committee on Taxonomy of Viruses (ICTV) rejected a proposal (2010.010bV) to formally recognize these names, as they do not designate names for subtypes, variants, strains, or other subspecies level groupings.[30] As such, the widely used common names are not formally recognized as part of the taxonomic nomenclature. In particular, "Ebola virus" does not have an official meaning recognized by ICTV, and rather they continue to use and recommend only the species designation Zaire ebolavirus.

The threshold for putting isolates into different species is usually a difference of more than 30% at the nucleotide level, compared to the type strain. If a virus is in a given species but differs from the type strain by more than 10% at the nucleotide level, it is proposed that it be named as a new virus. As of 2019, none of the Ebolavirus species contain members divergent enough to receive more than one "virus" designation.





Genus Ebolavirus: species and viruses
Species name (Abbreviation)                

Virus common name (Abbreviation)
Bombali ebolavirus Bombali virus (BOMV)
Bundibugyo ebolavirus (BEBOV) Bundibugyo virus(BDBV)
 Reston ebolavirus (REBOV) Reston virus (RESTV)
Sudan ebolavirus (SEBOV) Sudan virus (SUDV)
TaĂŻ Forest ebolavirus (TEBOV; previously CIEBOV) TaĂŻ Forest virus (TAFV)
Zaire ebolavirus (ZEBOV) Ebola virus (EBOV)






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Simian Immunodeficiency Virus (SIV) from Sun-Tailed Monkeys (Cercopithecus solatus): Evidence for Host-Dependent Evolution of SIV within the C. lhoesti Superspecies

1999

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC104300/



-----------------------------------------------------


 Non-Human Primates, Retroviruses, and Zoonotic Infection Risks in the Human Population

https://www.nature.com/scitable/knowledge/library/non-human-primates-retroviruses-and-zoonotic-infection-59119998/



----------------------------------------------------------




A Cophylogenetic Perspective of RNA–Virus Evolution

January 2004

https://academic.oup.com/mbe/article/21/1/45/1114580



-------------------------------------------------------



Can Viruses Make Us Human?


http://www.somosbacteriasyvirus.com/canviruses.pdf



------------------------------------------------------



Shedding subspecies: The influence of genetics on reptile subspecies taxonomy

2013


http://people.cst.cmich.edu/swans1bj/torstrom%20et%20al%202014.pdf

 


---------------------------------------------------------


Explaining the Divergence of the Marine Iguana Subspecies on Espa

https://www.amnh.org/learn-teach/curriculum-collections/young-naturalist-awards/winning-essays/2004/explaining-the-divergence-of-the-marine-iguana-subspecies-on-espa


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The incredible shrinking sea lizards

31 March 2017

https://www.bbc.co.uk/bbcthree/article/c0a61ac9-0f43-4e8e-95e6-d211543e7191




-----------------------------------------------------------------------------


 List of Marine Mammal Species and Subspecies

https://marinemammalscience.org/species-information/list-marine-mammal-species-subspecies/


------------------------------------------------------



Body Size, Performance and Fitness in Galapagos Marine Iguanas

01 July 2003

https://academic.oup.com/icb/article/43/3/376/623034


--------------------------------------------------------------------------------


How sea level influenced evolution in the Galapagos

2014

Recent shifts in sea level, particularly the lows, may have had a major influence on evolution in the Galapagos, according to new research.


https://www.theguardian.com/science/animal-magic/2014/apr/24/sea-level-evolution-galapagos



-------------------------------------------------------------------------------



Iguana-sized dinosaur cousin discovered in Antarctica


January 31, 2019

https://www.burkemuseum.org/news/iguana-sized-dinosaur-cousin-discovered-antarctica


------------------------------------------------------------------------------



Photographer documents the plight of the Galapagos Islands' iguanas as scientists warn climate change and severe El Nino events are destroying their food source

2 April 2019


https://www.dailymail.co.uk/sciencetech/article-6876747/Shocking-images-reveal-rotting-lizards-Galapagos-El-Nino-destroys-food-supply.html


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Bite force and cranial bone strain in four species of lizards


2018

https://jeb.biologists.org/content/jexbio/221/23/jeb180240.full.pdf?with-ds=yes



------------------------------------------------------------------------------



The Secrets of the Galapagos Marine Iguanas

October 25, 2016

https://www.lapintagalapagoscruise.com/galapagos-marine-iguanas/





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The Evolution of Marine Reptiles

19 May 2009


https://evolution-outreach.biomedcentral.com/articles/10.1007/s12052-009-0139-y



------------------------------------------------------------------------------


Iguana

https://en.wikipedia.org/wiki/Iguana


-----------------------------------------------------------------------------



The skull bones of the Iguana iguana



https://www.researchgate.net/publication/291392301_The_skull_bones_of_the_Iguana_iguana



----------------------------------------------------------------------------



Skull Development, Ossification Pattern, and Adult Shape in the Emerging Lizard Model Organism Pogona vitticeps: A Comparative Analysis With Other Squamates

2018




























https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882870/



-----------------------------------------------------------------------------




The pink Galapagos iguana that Darwin never saw

January 5, 2009

https://www.discovermagazine.com/planet-earth/the-pink-galapagos-iguana-that-darwin-never-saw



-----------------------------------------------------------------------------




Feeding  Strategies in Marine Snakes: An Analysis of Evolutionary, Morphological, Behavioral and Ecological  Relationships

1983

https://academic.oup.com/icb/article/23/2/411/302332




------------------------------------------------------------------------------




What our ancestors’ third eye reveals about the evolution of mammals to warm blood


November 13, 2016











https://theconversation.com/what-our-ancestors-third-eye-reveals-about-the-evolution-of-mammals-to-warm-blood-68454



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Genetic Analysis Shows Tuatara Is The Strangest Animal on Earth

Aug 22, 2020

 



 

https://www.youtube.com/watch?v=PWywZyzmBDE



-----------------------------------------------------------------------------



Giant Four-eyed Lizard May Change Paradigm of Evolution

Apr 04, 2018

Four-foot monitor which lived 49 million years ago in Wyoming indicates that the third eye in lizards evolved independently from everyone else's third eye, which had not been expected




(Dorsal view of the head of an anole (Anolis carolinensis lizard) clearly showing the third eye - marked by a green frame).

https://www.haaretz.com/science-and-health/MAGAZINE-giant-four-eyed-lizard-may-change-paradigm-of-evolution-1.5976440



--------------------------------------------------------------------------------




This sea snake gathers oxygen through its forehead


05 September 2019




 




https://cosmosmagazine.com/biology/this-sea-snake-gathers-oxygen-through-its-forehead



----------------------------------------------------------------------------



The Deadliest Sea Snake is actually two look-alike species


https://www.discovermagazine.com/planet-earth/the-deadliest-sea-snake-is-actually-two-look-alike-species




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Heterochronic Shifts Mediate Ecomorphological Convergence in Skull Shape of Microcephalic Sea Snakes.

2019

https://www.ncbi.nlm.nih.gov/pubmed/31065670




------------------------------------------------------------------------------




Did snakes evolve from ancient sea serpents?

June 17, 2016

https://phys.org/news/2016-06-snakes-evolve-ancient-sea-serpents.html

One of the enduring controversies in evolution is why snakes evolved their long, limbless bodies.

The prevailing theory is that they evolved from lizards and are really just an extreme type of legless lizard. And as many long-bodied lizards are burrowers, there is a widespread view that snakes developed their serpentine bodies underground.

But a study of a primordial four-legged fossil snake published this week suggests it was aquatic. This suggests snakes lost their legs and elongated their bodies underwater, for eel-like swimming, before crawling ashore aeons later.

The fossil in question is one of the most exquisite and controversial fossils of modern times. Dubbed Tetrapodophis (meaning "four-legged snake"), it lived alongside the dinosaurs in what is now Brazil, about 120 million years ago.

Amazingly, almost every single bone is preserved in this tiny worm-sized fossil, including four small but perfectly-formed legs.




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This is how the ancestor of modern snakes could have looked

3 July 2019

https://www.nhm.ac.uk/discover/news/2019/july/this-is-how-the-ancestor-of-modern-snakes-could-have-looked.html



Researchers have reconstructed the ancestral snake head.

It is part of a larger project to create 3D reconstructions of how the skull evolved.

Snakes and lizards (squamates) are part of a diverse group that includes burrowing snakes, gliding lizards and climbing chameleons. The animals in this group live all over the world in a huge variety of habitats, which means they all have very different skull shapes.

Comparing all their skull shapes wasn't an easy task - there are few points of obvious comparison - but a team of researchers have succeeded. Scientists from the UK, USA, Germany and France used cutting-edge imaging techniques and hundreds of specimens from both extinct and living species.

Prof Anjali Goswami, research leader at the Museum, explains, 'We capture lots of surface landmarks across the bones to get a better 3D picture of the animal's skull.

'CT scanning and laser scanning in the Museum's Imaging and Analysis Centre are making this possible. The Museum is one of the best places in the world for these types of facilities, and it is shaping how science can be done differently.

'Once we have this nice dataset with 1,000 or more data points across the skull, we use various methods and computer programmes to examine how skull shape has changed through time.'



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Beautifully Preserved Skull of 'Biblical Snake' with Hind Legs Discovered

November 20, 2019

https://www.livescience.com/snake-with-legs-skull.html



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A New Snake Skull from the Paleocene of Bolivia Sheds Light on the Evolution of Macrostomatans


March 1, 2013

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057583



------------------------------------------------------------------------------



The Evolution of the Tongue of Snakes, and its Bearing on Snake Origins

https://link.springer.com/chapter/10.1007/978-1-4684-9063-3_8



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Scientists reconstruct genome of common ancestor of crocodiles, birds, dinosaurs

Crocodiles found to have one of the most slowly evolving genomes, whereas the pace of genetic change has been much faster in birds

December 11, 2014













https://news.ucsc.edu/2014/12/crocodile-genomes.html




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At the feet of the dinosaurs: the early history and radiation of lizards

2002

http://aerg.canberra.edu.au/library/sex_general/2003_Evans_Review_squamate_evolution.pdf




------------------------------------------------------------------------------

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How Titanoboa, the 40-Foot-Long Snake, Was Found

April 2012

https://www.smithsonianmag.com/science-nature/how-titanoboa-the-40-foot-long-snake-was-found-115791429/



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Ancient Komodo Dragon Has Space-age Skull

April 14, 2008

https://www.sciencedaily.com/releases/2008/04/080414091357.htm



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Cranial performance in the Komodo dragon (Varanus komodoensis) as revealed by high-resolution 3-D finite element analysis

2008







(FE model showing distribution of pretensioned muscle trusses (Table 1). MAEM: m. adductor externus mandibulae; MPST = m. pseudotemporalis superficialis and profundus; MAMP = m. adductor mandibulae posterior; MPT = m. pterygoid; a, articular; cp, coronoid process; d, dentary; ec, ectopterygoid; ep, epipterygoid; fr, frontal; j, jugal; l, lacrimal; mx, maxilla; n, nasal; pa, parietal; pf, prefrontal; pm, premaxilla; po, prootic; por-pof, postorbital + postfrontal; pt, pterygoid; qu, quadrate; sa, surangular; sm, septomaxilla; s, squamosal; sp, splenial).




https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423397/


----------------------------------------------------------------------------



Researchers Discover the Surprising Reason Why Komodo Dragons Have Such Elaborate Armor


 September 12, 2019










(Bony plates called osteoderms (colored orange) cover the skull of an adult Komodo dragon)







(Komodo dragon osteoderms. The insets show the four basic osteoderm shapes found on the adult specimen. From top to bottom: rosette; platy; dendritic; and vermiform).









(3-D reconstructions of different reptile skulls and their osteoderms. The left column shows a side view and the right column a view from the top. The reptiles are as follows: A: Komodo dragon. B: Earless monitor lizard. C: Gila monster. D: Asian water monitor. Scale bar is one centimeter).



https://scitechdaily.com/researchers-discover-the-surprising-reason-why-komodo-dragons-have-such-elaborate-armor/


-----------------------------------------------------------------------------




Bones in different races

https://depts.washington.edu/bonebio/bonAbout/race.html


---------------------


Skull thickness of Black and White races.

https://www.ncbi.nlm.nih.gov/pubmed/1224277


------------------------


Thickness of the normal skull in the American Blacks and Whites.

https://www.ncbi.nlm.nih.gov/pubmed/1155589

Abstract

Normal skull thickness has been measured in a general hospital population of 300 blacks and 200 whites in America. In both groups, there is a rapid increase in skull thickness during the first two decades of life, followed by a small uniform increase reaching a peak in the fifth and sixth decades. The sex differences are variable, but in certain age groups the females in both races have significatly thicker parietal and occipital bones than their male counterpart. The frontal bone is thicker in the white male than in the black, and the parietooccipital thicker in the blacks than in the whites. Some suggestions are offered to explain the sex and racial difference noted.


----------------------------


Sex, Race, Brains, and Calipers

1993

https://www.discovermagazine.com/mind/sex-race-brains-and-calipers


-----------------------------


Physical Anthropology of the Jews. I.-The Cephalic Index

https://www.jstor.org/stable/659377?seq=1#metadata_info_tab_contents


---------------------------


Ashkenazi Jewish Genetic Panel (AJGP)

What Are Ashkenazi Jewish Genetic Diseases?

Ashkenazi Jewish genetic diseases are a group of rare disorders that occur more often in people of Eastern European (Ashkenazi) Jewish heritage than in the general population. Even though most of these diseases are severe and can cause early death, some can be treated to reduce symptoms and prolong life. Some of these diseases can be found during pregnancy through chorionic villus sampling (CVS) or amniocentesis. This testing is done usually if one or both parents are carriers of a genetic disease.

Diseases in this group include:

    Bloom syndrome. Babies with this disease are born small and remain shorter than normal as they grow. Their skin may look red, and they have more lung and ear infections than children normally have.
    Canavan disease. This disease gradually destroys brain tissue.
    Cystic fibrosis. This disease causes very thick mucus in the lungs and problems with digesting food.
    Familial dysautonomia (FD). People with this problem cannot feel pain, they sweat a lot, and they have trouble with speech and coordination.
    Fanconi anemia. People with this problem do not have enough blood cells and have problems with the heart, kidneys, arms, or legs. They also are more likely to get cancer.
    Gaucher disease. This disease causes a type of fat called glucocerebroside to build up in certain cells of the liver, spleen, and bone marrow.
    Mucolipidosis IV. This problem causes the nervous system to deteriorate, or break down, over time.
    Niemann-Pick disease (type A). This disease causes a type of fat called sphingomyelin to build up in cells of the liver, spleen, lymph nodes, and bone marrow.
    Tay-Sachs disease. This disease causes a type of fat called ganglioside to build up in the cells of the brain and nervous system.
    Torsion dystonia. People with this problem have ongoing spasms that twist the muscles in their arms, legs, and sometimes their body. Testing for this condition may not always be done.

About 1 out of 4 people of Ashkenazi Jewish heritage is a carrier of one of these genetic conditions, most commonly of Gaucher disease, cystic fibrosis, Tay-Sachs disease, familial dysautonomia, or Canavan disease.

    Pregnancy: Should I Have Amniocentesis?
    Pregnancy: Should I Have Chorionic Villus Sampling?

https://www.uofmhealth.org/health-library/tv7879



---------------------------




Jewish Genetic Diseases

https://www.jewishgeneticdiseases.org/jewish-genetic-diseases/

JGDC provides information about diseases that are commonly found in the Jewish (Ashkenazi, Sephardi, and Mizrahi) population and would be important to be included in a carrier screening panel.  Please keep in mind that the availability of testing for these diseases might differ between labs and it is important to discuss your options with a genetics professional before being tested.

Most expanded carrier screening panels will include the diseases listed below as well as many other diseases common to individuals of all ethnicities.  Many medical and genetics profesionals are currently supporting expanded carrier screening for all individuals of child bearing age, in lieu of ethnic specific testing.
Diseases Common to all Jewish Groups

Cystic Fibrosis

Familial Mediterranean Fever

Fragile X Syndrome

Glycogen Storage Disease Type II

Phenylalanine Hydroxylase Deficiency

Retinitis Pigmentosa 28

Smith-Lemli-Opitz Syndrome

Spinal Muscular Atrophy

Tay-Sachs Disease

Wilson Disease




Ashkenazi Jewish Diseases

3-Phosphoglycerate Dehydrogenase Deficiency

Abetalipoproteinemia

Alport Syndrome

Arthrogryposis, Mental Retardation and Seizures

Bardet-Biedl Syndrome

Bloom Syndrome

Canavan Disease

Carnitine Palmitoyltransferase ll Deficiency

Choreoacanthocytosis

Congenital Amegakaryocytic Thrombocytopenia

Congenital Disorder of Glycosylation la

Cystic Fibrosis

Deafness-Autosomal Recessive 77

Dyskeratosis Congenita, Autosomal Recessive

Ehlers-Danlos VllC

Enhanced S-Cone Syndrome

Factor XI Deficiency

Familial Dysautonomia

Familial Hypercholesterolemia

Familial Hyperinsulinism

Familial Mediterranean Fever

Fanconi Anemia-Group C

Fragile X Syndrome

Galactosemia

Gaucher Disease

Glycogen Storage Disease 1A

Glycogen Storage Disease Type II

Glycogen Storage Disease Type IV / Adult Polyglucosan Body Disease

Glycogen Storage Disease Type VII

Hermansky-Pudlak Syndrome 3

Joubert Syndrome 2

Lipoamide Dehydrogenase Deficiency

Maple Syrup Urine Disease 1B

Mitochondrial Complex 1 Deficiency

Mucolipidosis IV (ML4)

Multiple Sulphatase Deficiency

Nemaline Myopathy 2

Niemann-Pick Disease Type A/B

Nonsyndromic Hearing Loss

Osteopetrosis 1

Phenylalanine Hydroxylase Deficiency

Polycystic Kidney Disease, Autosomal Recessive

Pontocerebellar Hypoplasia Type 1A

Primary Ciliary Dyskinesia DNAH5

Primary Ciliary Dyskinesia DNAI1

Primary Ciliary Dyskinesia DNAI2

Primary Hyperoxaluria Type 3

Retinitis Pigmentosa 28

Retinitis Pigmentosa 59

Smith-Lemli-Opitz Syndrome

Spinal Muscular Atrophy

Tay-Sachs Disease

Tyrosinemia-Type 1

Usher Syndrome-Type IF

Usher Syndrome-Type III

Walker Warburg Syndrome and Other FKTN-Related Dystrophies

Wilson Disease

Zellweger Syndrome Spectrum-PEX2




Sephardi-Mizrahi Jewish Diseases

3-Methylglutaconic Aciduria, Type III / Optic Atrophy 3, with Cataract

Acute Infantile Liver Failure

Adrenoleukodystrophy-X-Linked ABCD1

Asparagine Synthetase Deficiency

Ataxia Telangiectasia

Beta-Globin-Related Hemoglobinopathies

Cerebrotendinous Xanthomatosis

Chronic Granulomatous Disease

Congenital Insensitivity to Pain with Anhidrosis

Congenital Myasthenic Syndrome

Corticosterone Methyloxidase Deficiency

Cystic Fibrosis

Cystinosis

Familial Mediterranean Fever

Fanconi Anemia-Group A

Fragile X Syndrome

Glycogen Storage Disease Type II

Glycogen Storage Disease Type III

Glycogen Storage Disease Type V

Hereditary Spastic Paraparesis 49

Homocystinuria due to MTHFR Deficiency

Inclusion Body Myopathy 2

Infantile Cerebral and Cerebellar Atrophy

Leber Congenital Amaurosis 2-Retinitis Pigmentosa 20

Limb Girdle Muscular Dystrophy Type 2B

Megalencephalic Leukoencephalopathy with Subcortical Cysts

Metachromatic Leukodystrophy

Microphthalmia / Anophthalmia

Mitochondrial Complex 1 Deficiency

Mitochondrial Myopathy and Sideroblastic Anemia

Myoneurogastrointestinal Encephalopathy

Omenn Syndrome

Ornithine Aminotransferase Deficiency

Phenylalanine Hydroxylase Deficiency

Polyglandular Autoimmune Syndrome, Type I

Pontocerebellar Hypoplasia Type 6

Progressive Cerebello-Cerebral Atrophy

Renal Tubular Acidosis and Deafness

Retinitis Pigmentosa 25

Retinitis Pigmentosa 26

Retinitis Pigmentosa 28

Smith-Lemli-Opitz Syndrome

Spinal Muscular Atrophy

Tay-Sachs Disease

Usher Syndrome-Type IIA

Wilson Disease

Wolman Disease / Cholesteryl Ester Storage Disease

Zellweger Syndrome Spectrum




----------------------------------------------------------------





Medical genetics of Jews

https://en.wikipedia.org/wiki/Medical_genetics_of_Jews

Genetic disorders common in Ashkenazi Jews Disease     Mode of inheritance     Gene     Carrier frequency
 Favism     X-linked     G6PD    
 Bloom syndrome     Autosomal recessive     BLM     1/100
 Breast cancer and ovarian cancer     Autosomal dominant     BRCA1 or BRCA2     1/100 and 1/75, respectively
 Canavan disease     Autosomal recessive     ASPA     1/60
 Congenital deafness     Autosomal recessive     GJB2 or GJB6     1/25
 Cystic fibrosis     Autosomal recessive     CFTR     1/25
 Haemophilia C     Autosomal recessive     F11     1/12
 Familial dysautonomia     Autosomal recessive     IKBKAP     1/30
 Familial hypercholesterolemia     Autosomal dominant     LDLR     1/69
 Familial hyperinsulinism     Autosomal recessive     ABCC8     1/125–1/160
 Fanconi anemia C     Autosomal recessive     FACC     1/100
 Gaucher disease     Autosomal recessive     GBA     1/7–1/18
 Glycogen Storage Disease type 1a     Autosomal recessive     G6PC     1/71
 Mucolipidosis IV     Autosomal recessive     MCOLN1     1/110
 Niemann–Pick (type A)     Autosomal recessive     SMPD1     1/90
 Nonclassical 21 OHase deficiency     Autosomal recessive     CPY21     1/6
 Parkinson's disease     Autosomal dominant     LRRK2     1/42[18]
 Tay–Sachs     Autosomal recessive     HEXA     1/25–1/30
 Torsion dystonia     Autosomal dominant     DYT1     1/4000
 Usher syndrome     Autosomal recessive     PCDH15     1/72





------------------------------------------------------------------


Are the Jews a Race?


https://www.marxists.org/archive/kautsky/1914/jewsrace/ch05.htm


------------------------------------------------



‘Not a race but only a people after all’: the racial origins of the Jews in fin-de-siĂšcle anthropology


Apr 2008


https://www.tandfonline.com/doi/full/10.1080/00313220801996063?scroll=top&needAccess=true&



------------------------------------------------------------------


CRANIOMETRY:

http://www.jewishencyclopedia.com/articles/4729-craniometry


The methods of measuring skulls for the purpose of determining certain topographical relations, the most important measurement of the skull being the cranial index, or the cephalic index in case the measurements are taken on the living. This consists in the ratio of the width of the head above the ears to the length of the head from the forehead to the most distant point at the back of the head. The cephalic index is expressed by multiplying the width of the head by 100 and dividing the product by the length. Thus, supposing a head to be 153 mm. wide and 186 mm. long, then 153 × 100/186 = 82.26, the cephalic index. The broader or rounder a head is, the higher is its cephalic index, and vice versa. When the cephalic index is above 80 anthropologists term it "brachycephalic"; between 75 and 80, "mesocephalic"; and less than 75, "dolichocephalic."

There have been but few measurements of Jewish skulls, most of the measurements of Jews having been taken on the living. The following is a list of the measurements of 100 Jewish skulls taken by various anthropologists:

As is the universal rule, the circumference of the head of the male is greater than that of the female by about 2.5 cm. (1 inch). Another point worth noting is that (wherever data are obtainable) the circumference of the head among the Jews is, as a rule, greater than that among the races with whom they dwell.

The most important problem suggested by a study of craniometrical results concerning Jews is the relation of the type head of the modern Jews to that of the ancient Hebrews and to the modern Semitic skulls. The pure Semitic skull is dolichocephalic, as may be seen from a study of the heads of modern Arabs, Abyssinians, Syrians, etc. The cephalic index of these races is from 73 to 77. As is at present accepted by nearly all anthropologists, the shape of the head is the most stable characteristic of a given race. It is little if at all influenced by climate, environment, nutrition, or sexual and social selection. The only way the type of the head may change is by intermixture with other races. If the ancient Hebrews were of the same stock as the modern non-Jewish Semites, and if the modern Jews are their descendants, then a pure dolichocephalic type of head would be expected among the Jews. As has been seen, all the results of craniometry prove that the Jews are brachycephalic, and that the dolichocephalic form is only found among them in less than two per cent of cases.

Ancient Jewish Skulls.

This can be explained in two ways: either the modern Jews have very little Semitic blood in their veins, as Lombroso, Luschan, and others are inclined to think, or the ancient Hebrews may have been a brachycephalic race. In order to establish this, an examination is necessary of more skulls of ancient Hebrews, which are not available at present. The only skulls of ancient Hebrews recorded are five obtained by Lombroso from the catacomb of St. Calixtus in Rome, dating back to 150 C.E. Lombroso aptly remarks that these skulls are of great importance, because at the period from which they are derived (second century), there could not have been any considerable racial intermixture of the Jews with other peoples, and the cranial typethey represent should be considered pure. The cranial indexes of these skulls are 80, 76.1, 78, 83.4, and 75.1, giving an average cephalic index for the living of 80.5, which is far above the cephalic index of the non-Jewish Semites.

Of course, no positive conclusion can be drawn from only five skulls; still, the fact that among these are found two brachycephalic and only one dolichocephalic, points strongly against the opinion that the ancient Hebrews were a purely dolichocephalic race.

The twelve skulls from a Jewish cemetery in Basel, of the thirteenth and fourteenth centuries, which have been examined by Kollmann, are even more brachycephalic than those of contemporary Jews. The average cranial index of these skulls is 84.66; i.e., a cephalic index of 86.66. This again shows that the brachycephalism of the modern Jews is not of recent origin.

It can therefore be stated that the modern European Jews are shown by craniometrical evidence to be a pure type, and that no evidence of appreciable racial intermixture is discoverable. The opinion that the Sephardim are dolichocephalic, while the Ashkenazim are brachycephalic, is not supported by craniometrical research on European Jews. The measurements by Jacobs, Lombroso, Livi, and GlĂŒck prove that the Sephardim are almost as brachycephalic as are the Ashkenazim, as can be seen from the accompanying table. Jacobs' measurements of the Jews in London show that the percentage of dolichocephalic is even larger among the Ashkenazim, being 28.3 per cent, as against only 17 per cent among Sephardim.


---------------------------------------


Sex and Race Determination From The Base Of The Skull

https://trace.tennessee.edu/cgi/viewcontent.cgi?article=5582&context=utk_gradthes


-----------------------------------------



Forensics 101: Race Determination Based on the Skull

July 10, 2012

https://jenjdanna.com/blog/2012/7/10/forensics-101-race-determination-based-on-the-skull.html


Mouth: Whites tends to have smaller teeth, often with significant crowding and impacted third molars, and frequently exhibiting an overbite. Blacks rarely have crowding and the upper teeth often project outwards due to the angled shape of the maxilla. American Indians have well spaced teeth but often exhibit sclerosed dentition—when calcium deposits build up inside the tooth, thinning the root canal—leaving teeth loose within the mandible and easily cracked.

The palate and palatine suture:  The hard palate is the bony structure at the top of the mouth bordered by the upper teeth. In American Indians, the palate is elliptical, with the ‘U’ shape angling in at the back teeth. In blacks, the palate is hyperbolic—a perfect ‘U’ shape with straight lines. And in whites, the palate is parabolic with the ends of the ‘U’ flaring outwards. The transverse palatine suture that horizontally transects the palate also varies by race: It is straight in American Indians, curved in blacks, and a jagged line in whites.

Incisors: The shape of the incisors is the most important indicator of race in the teeth. In American Indians (and East Asians, both of Mongoloid ancestry), the incisors are shovel-shaped, named because the inner surface is scooped or curved. Black and whites both have blade-form incisors where the tooth has a flat profile.

The nose: The nose provides multiple race indicators. In whites, the nasal aperture is long and narrow, with a high bridge and a sharp nasal sill (the lower edge of the nasal aperture projects sharply outwards). In blacks, the nasal aperture is short and wide with a low bridge and a guttered or trough-like nasal sill. In American Indians, the nasal aperture is medium-sized with both a medium bridge and nasal sill.

The mastoid process: The shape of the mastoid process differs between the races. In blacks, the bony projection is wide, in whites it is narrow and pointed, and in American Indians, a secondary smaller projection forms on the back surface of the mastoid process.

Rarely do all of these indicators point firmly to a single race. Instead, it is the story told by the majority of physical characteristics that suggests the victim’s ethnic background. If in doubt, additional post-cranial (skeletal features in the rest of the body) can help indicate race as well.

The information gathered by a forensic anthropologist concerning age, sex and race can lead criminal investigators to a narrowed missing persons search and hopefully to a definitive victim identification.



-----------------------------------------


Black History By The Bones (Debated)

http://realhistoryww.com/world_history/ancient/Misc/By_the_bones.htm


------------------------------------------


Brain size, IQ, and racial-group differences: Evidence from musculoskeletal traits

https://menghublog.wordpress.com/2012/04/20/brain-size-iq-and-racial-group-differences-evidence-from-musculoskeletal-traits/


------------------------------------------


The story of human evolution in Africa is undergoing a major rewrite

2017

Did scientists discover the oldest Homo sapiens remains on record? Depends on your definition of what’s human. 

https://www.vox.com/science-and-health/2017/6/7/15745714/nature-homo-sapien-remains-jebel-irhoud


------------------------------------------



Superior: The Return of Race Science—A Review

June 5, 2019

https://quillette.com/2019/06/05/superior-the-return-of-race-science-a-review/



------------------------------------------

Human Male and Female Skulls: African, Asian, and European

https://boneclones.com/product/human-male-and-female-skulls-african-asian-and-european-COMP-120-SET


------------------------------------------

An ancient skull found in Australia suggests our ancestors modified their skulls. Some people still do it today, but why?

14 October 2014

http://www.bbc.com/earth/story/20141013-why-we-reshape-childrens-skulls


------------------------------------------


Activity: Can You Identify Ancestry?

https://naturalhistory.si.edu/sites/default/files/media/file/wibidentifyancestryfinal.pdf


-------------------------------------------


 An Updated Prehistory of the Human Pelvis







 





 




 For a long time, paleoanthropologists had thought that the differences among hominins could be explained by the space requirements of the birth canal. This explanation is now undergoing some change, however, as discussed in an American Scientist column by Pat Shipman (“Why Is Human Childbirth So Painful?,” November–December 2013). Chimpanzees, with their elongated pelvis (a product of the tall wings and long ischium), have a spacious birth canal that their small-brained infants fit through without difficulty. By comparison, the shorter ischium and reoriented ilium of the human pelvis produce a smaller birth canal, which—together with the development of larger-brained infants—can make childbirth both painful and problematic.


https://www.americanscientist.org/article/an-updated-prehistory-of-the-human-pelvis



------------------------------------------


How have we changed since our species first appeared?

https://australianmuseum.net.au/learn/science/human-evolution/how-have-we-changed-since-our-species-first-appeared/


------------------------------------------


{Many scientists say the reason why blacks and Orientals have more eye and nasal problems is that they have deformed skulls}.


---------------------------------


Why is it that many people from Africa have bloodshot red eyes?


https://www.reddit.com/r/NoStupidQuestions/comments/6b2292/why_is_it_that_many_people_from_africa_have/

orualofglome
32 points ·
2 years ago

Actual African living in Africa: In addition to the first comment 2 things that make my eyes red are exhaustion, dryness with a lot of dust and many people use wood for cooking fuel and the smoke makes eyes rather red.

Any other reasons I am unaware of

moogette
13 points ·
2 years ago

    Some black people have yellow tinted eyes because of the heavy concentration of melanin present in their sclera--- the white part of the eye.

    Melanin is also responsible for the color of one's iris and one's skin tone. Palms and soles of feet lack great amounts of melanin so the color is more uniform in all people.

    Additionally, many people in Africa that live in poverty tend to have higher than average issues with their livers, causing a build-up of old red blood cells. This is known as cirrhosis. This most commonly occurs with premature / malnutrition newborns as well as adults who have not been treated properly.


-----------------------------------


People with skin of color can get rosacea

https://www.aad.org/public/diseases/rosacea/what-is/skin-color


Rosacea is a common condition that affects the skin on the face and sometimes the eyes. It often begins with a tendency to flush or blush easily. With time, that warm feeling on the face tends to last longer and may eventually become constant.

Studies show that when people of color develop rosacea, the early signs, such as flushing, can be missed or mistaken for another condition.

Without treatment, rosacea can worsen. Your face may burn and sting every time water touches it or you apply a skin care product. Some people develop acne-like breakouts. When rosacea affects the eyes, it can cause problems with your eyesight.

Even when it worsens, rosacea can be missed in people who have skin of color.

Signs of rosacea in skin of color

If you have skin of color, dermatologists recommend that you make a dermatology appointment if you notice any of the following on your face:

    A warm feeling most of the time

    Dry, swollen skin and patches of darker skin

    A dusky brown discoloration to your skin

    Acne-like breakouts that acne treatment won’t clear

    Yellowish-brown, hard bumps around your mouth, eyes, or both

    Burning or stinging when you apply skin care products

    Swelling and thickening skin on your nose, cheeks, chin, or forehead

Signs that rosacea is affecting your eyes

When rosacea affects the eyes, it’s called ocular rosacea. Here are signs that rosacea may be affecting your eyes:

    Swollen, warm eyelids

    Red, bloodshot eyes

    Pink eye (also known as conjunctivitis)

    Crusty eyelids or eyelashes

    Tearing (or dry eyes)

    A feeling you have something in your eye

    Burning and stinging in your eyes

    Itchy, irritated eyes

    Sensitivity to light

Even when the rosacea on your skin is mild, you can develop eye problems. If you have any of these signs or symptoms, see a board-certified dermatologist or ophthalmologist.

Without treatment, ocular rosacea can affect your eyesight.
Another sign of rosacea: It worsens with certain activities

If you have rosacea, you may notice that it worsens at certain times of the year or when you do certain things. In the winter, your face may feel raw and irritated when you’re outside on a cold, windy day. After drinking a glass of red wine, your face may feel hot and uncomfortable.

Anything that worsens your rosacea is called a trigger. Many things can be a trigger, and triggers tend to vary from person to person. Some of the most common rosacea triggers are:

    Stress

    Sunlight

    Alcohol, especially red wine

    Wind

    Heat

    Spicy foods

    Hot beverages

    Exercise

    Some skin care or hair care products


-----------------------------------



Eye Health Among African Americans



African Americans are at higher risk for some eye diseases, including cataract, glaucoma, and diabetic retinopathy. Many of these diseases don’t have symptoms at first, and can cause vision loss or blindness if they’re not treated.

African Americans have some of the highest rates of vision loss and blindness caused by eye disease — and these rates are getting higher. The good news is that comprehensive dilated eye exams can find many of these eye diseases early, when they’re often easier to treat. 

Our Write the Vision initiative can help you spread the word about healthy vision among African Americans in your community. You can help prevent vision loss and blindness!


https://www.nei.nih.gov/learn-about-eye-health/resources-for-health-educators/eye-health-among-african-americans


-----------------------------------


There is something weird about this gorilla's eyes

Look closely and you'll see this gorillas has eyes that are more like a human's

http://www.bbc.com/earth/story/20150808-gorillas-with-human-eyes


------------------------------------



 Study   of   Cephalic   Index   in   Indian   Students


The mean cephalic index in males wasrecorded  to  be  77.92±5.2.  Head  shape  wasclassified by cephalic index in which dominanttype   was   dolicocephalic   (33%)   andbrachycephalic  (33%),  followed  by  27%mesocephalic  and  6%  hyperbrachycephalic.The  mean  cephalic  index  in  female  was80.85±7.71 which showed that majority werebrachycephalic  (33%),  with  29%  each  ofdolicocephalic and hyperbrachycephalic andleast    common    mesocephalic    (9%).Comparison of percentage of male and femalecephalic index is depicted in Graph 1...

In our study, dominant type of head shape in maleswas dolicocephalic (33%) and brachycephalic (33%) but themean cephalic index was 77.92 (mesocephalic). This findingof dolicocephalic was similar to study done on Indian males(Bhatia  et  al.,  1995)  in  which  58.5%  of  population  wasdolicocephalic, but not similar with the study by del Sol in
Chile  (66%),  Bhasin  (2006),  Shah  &  Jadhav  in  Gujarati(41%)  which  showed  Mesocephalic  head  shape  wascommon. The dolicocephalic shape was a rare type found inIranian group about 7.5% in South Iran (Vojdani et al.), 1.5%in  North  Iran  (Golalipour,  2006b),  9%  in  Tehran(Abolhasanzadeh & Farahani), 7% in Indian gujarati (Shah& Jadhav) and about 2% in IX Region of Chile (del Sol).Also  in  our  study,  the  other  dominant  type  of  head  shapewas Brachycephalic (33%) which is similar to study doneon Turkman males (42.4 %) in North Iran (Golalipour et al.,2007)  and  Tehran  –  Iran  (36.6%)  (Abolhasanzadeh  &Farahani). In the present study least common type of male headshape was hyperbrachycephalic (6%). But this was dominanttype  observed  in  on  Fars  males  in  North  of  Iran  (52%)(Golalipour, 2006b), South Iran (34.3%) (Vojdani et al.).The Cephalic index of Indian females in present studywas 80.85. This finding was lower than Nakashima (1986)study with 87, Golalipour (2006a) study on native Fars groupwith 85, Turkman group 82.8 in North of Iran (Golalipour,2006b), Shah & Jadhav from India with 81.20. But higherthan Abolhasanzadeh & Farahani study in Tehran- center ofIran with 75, Buretic ́-Tomljanovic ́ et al. (2004) study inCroatia  with  79.23,  Ijaw  (78.24)  and  Igbo  (76.83)  tribescommunity (Oladipo & Olotu), Baysela state, Nigeria with72.24 (Eroje et al.). In  females  the  dominant  type  of  head  shape  wasbrachycephalic (33%). It is similar to other study in Tehran-Iran (42.7 %) (Abolhasanzadeh & Farahani), South of Iran(42.5%) (Vojdani et al.), and Shah & Jadhav study in India(49%).  But  in  a  study  of  Fars  female,  North  Iranhyperbrachycephalic  (53.6%)  (Golalipour,  2006a)  wasdominant which in our present study was 29%.In our study rare type of head shape was mesocephalic(9%) which was not similar to other study such as Tehran-Iran (9.9%) (Abolhasanzadeh & Farahani), Fars (0.1%) andTurkman, North of Iran (0.5%) (Golalipour, 2006a), SouthIran (4.84%) (Vojdani et al.), and Shah & Jadhav in India(0.3%) where dolicocephalic was rare.This study showed that the mean cephalic index offemale was significantly higher than those of male (p=0.025).The mean cephalic index of this study was 78.92±6.31 whichsays  that  the  dominant  head  shape  among  Indians  wasbrachycephaly which was lower than Shah & Jadhav studyin  India  with  80.42,  Bhargava  &  Kher  (1961)  Berelas  ofCentral  India  79.80,  Chile  (80.42)  by  del  Sol,  Fars  maleswith 84.8 (Golalipour, 2006b), Fawehinmi et al. (2008) studyin Port arcourt, Nigeria with 79.80.

But the Cephalic index was higher when comparedto Abolhasanzadesh & Farahani study in Tehran – Iran with75, Bhargav & Kher (1960) for Bhils of Central India 76.98,Eroje et al. Ogbia, Nigeria with 72.96.This  shows  that  there  is  tendency  towardsbrachycephalisation. Comparing previous records of cephalicindex  with  recent  work  proves  tendency  towards"brachycephalisation" - evidence of continuous growh of brainmore in the lateral direction (Shah & Jadhav). Also, in tropi-cal  zones  head  form  is  longer  (dolichocephalic),  but  intemperate zones the head form is more round (mesocephalicor brachycephalic) (Bharati et al., 2001). Since India is in thepartly in temperate and tropical zone, the present classificationshows tendency to brachycephalization from dolicocephalic

The variations of head shape may be due to hereditaryfactor or environmental which may act as secondary effect(Golalipour et al., 2007). The kind of diet taken could alsoplay  a  role  in  influencing  the  dominant  head  shape.  Headshapes  can  also  change  from  one  generation  to  the  other.For instance, in the first generation of Japanese immigrantsin  Hawaii  it  was  noticed  that  they  had  an  increased  headbreadth, a decreased head length and a higher cephalic indexthan their parents (Heravi & Zieaee, 2002).With the help of above statistics the sex as well asrace  of  the  deceased  can  be  determined  accurately.  Thisknowledge is of immense importance to anthropologists aswell as forensic science experts.

http://www.intjmorphol.com/wp-content/uploads/2015/08/art_22_301.pdf



----------------------------



A study of cephalic index of Bengali subjects of Tripura for determination of race

2018

http://www.jmedsoc.org/article.asp?issn=0972-4958;year=2018;volume=32;issue=2;spage=91;epage=97;aulast=Chakrabarti

Background: There has been a common belief among the people of Tripura that the racial origin of the Bengali subjects is from Aryans.
Aims: The aim of this study was to determine the cephalic index of Bengali population of Tripura, for determination of their racial origin.

Setting and Design: A data-based study carried out in a tertiary care teaching institute, Agartala.
Materials and Methods: After obtaining ethical clearance from the Institutional Ethics Committee, this study was conducted on the cadavers of Bengali subjects of Tripura brought for medicolegal postmortem examination in a tertiary care teaching hospital in Tripura. A total number of 411 cases were selected at random for the study during April 2015–March 2016. Using a slide caliper (Martin's type), the maximum length and breadth of skull with and without soft tissue were measured and individual's cephalic index was calculated.
Statistical Analysis Used: Data collected were analyzed using the Statistical Package for Social Science.

Results: The study comprised 282 (68.6%) males and 129 (31.4%) females. Two hundred and twenty-one numbers of subjects (53.77%) were found to be mesaticephalic, while 184 subjects (44.76%) and 6 subjects (1.45%) were brachycephalic and dolichocephalic, respectively. In case of cephalic index without soft tissue, 233 subjects (56.69%) were mesaticephalic and 178 subjects (43.31%) were brachycephalic, whereas none was found to be dolichocephalic.
Conclusion: Among 411 numbers of subjects, when cephalic index was calculated with soft tissue, 221 numbers of subjects (53.77%) were found to be mesaticephalic, while 184 subjects (44.76%) and 6 subjects (1.45%) were brachycephalic and dolichocephalic, respectively. In case of cephalic index without soft tissue, 233 subjects (56.69%) were mesaticephalic and 178 subjects (43.31%) were brachycephalic, whereas none was found to be dolichocephalic.



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Bone Mineral Deficiency as the Main Factor of Dolichocephalic Head Flattening in Very-Low- Birth-Weight Infants

1994

https://www.nature.com/articles/pr1994292.pdf?origin=ppub



-----------------------------



Dolicocephalization in Cephalic Indices of Adult Yorubas of Nigeria

2014

https://www.hindawi.com/journals/janthro/2014/819472/

Abstract

Cephalic index is an important parameter useful in establishing racial and sexual dimorphism. This study was carried out to determine the cephalic indices of adult Yorubas of age 18 to 40 years. One thousand and twenty (1020) Yoruba adults consisting of 493 males and 527 females were recruited randomly for the study. These were all residents of Port Harcourt, Rivers State of Nigeria. The mean cephalic index of Yorubas without reference to gender was 74.39 ± 5.41. Dominant and rare types of head shapes are dolicocephalic (68.33%) and hyperbrachycephalic (5.00%), respectively. The mean cephalic indices were 75.02 ± 4.76 (mesocephalic) in males and 73.75 ± 5.13 (dolicocephalic) in females. We conclude that Yoruba males are mesocephalic while Yoruba females are dolicocephalic. Besides, this study also reveals dolicocephalization tending towards mesocephalization amongst Yorubas. These findings will be very useful in forensic science, physical and medical anthropology, and clinical practice, most especially craniofacial surgery as it presents a characteristic feature of the head configuration for this Nigerian race.



----------------------------



Cranian index of ancient skulls

https://anthrogenica.com/archive/index.php/t-5821.html?__cf_chl_jschl_tk__=b8743b6afc1b15c1cbd2ad58057a4814f152f043-1585552480-0-AYmjAIMqhKwsHPpQsx7LF6GobT-EViBMoJ6QnjRhnCieGGrUYMi3TNmed_fug_-MkRnFLmDpbAgvYixK4ZCcEE3PujIy7G4xNKcWUoRd-Dwb9VX8KWMj47n5IIIKBe8Pz9B_CRziFYsgIhY1S4uf4WxSsrhwIKrVWMpjNmOyDIaH_b3ljDe5YsR9-MNKUXFyUJ4OzfyPsSHXcn4THlTM8upIsxEY5nxEgIYNOS0Uga80vlA53Gn_iavJzAku54GZTZ8CVzEcC7dzbQx_KLTvk4wISQZNfVTU1NcMDWYj9YqZEzdqu95fAj6Krc26mWs7vA


----------------------------



What is your cephalic index?

https://www.eupedia.com/forum/archive/index.php/t-27058.html


----------------------------



Brachycephalic, dolichocephalic and mesocephalic: is it appropriate to describe the face using skull patterns?

2013

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512013000300025



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Displacement of brain regions in preterm infants with non-synostoticdolichocephaly investigated by MRI

2007

http://surfer.nmr.mgh.harvard.edu/pub/articles/2007/2007_-_Mewes_et_al._-_NeuroImage.pdf


----------------------------



Diseases related with Frontal bossing and Dolichocephaly

ISOLATED SCAPHOCEPHALY
OSTEOGENESIS IMPERFECTA TYPE 1
TRICHO-DENTO-OSSEOUS SYNDROME
ACROMESOMELIC DYSPLASIA, MAROTEAUX TYPE
CRANIOSYNOSTOSIS, BOSTON TYPE
THREE M SYNDROME 3; 3M3
THREE M SYNDROME 2; 3M2
CHILDHOOD-ONSET HYPOPHOSPHATASIA
MACROCEPHALY-DEVELOPMENTAL DELAY SYNDROME
SYNDROMIC MULTISYSTEM AUTOIMMUNE DISEASE DUE TO ITCH DEFICIENCY

https://www.mendelian.co/symptoms/frontal-bossing-and-dolichocephaly



----------------------------



Skull Malformation

https://www.sciencedirect.com/topics/medicine-and-dentistry/skull-malformation



----------------------------


Blindness in Africa: present situation and future needs

CONCLUSIONS Blindness prevalence rates vary widely but the evidence suggests that approximately 1% of Africans are blind. The major cause is cataract; trachoma and glaucoma are also important causes of blindness. The bulk of blindness in the region is preventable or curable. Efforts should focus on eye problems which are universally present and for which there are cost effective remedies, such as cataract and refractive problems and on those problems which occur focally and can be prevented by primary healthcare measures, such as trachoma, onchocerciasis, and vitamin A deficiency. Major development of staffing levels, infrastructure, and community programmes will be necessary to achieve Vision 2020 goals.

https://bjo.bmj.com/content/85/8/897



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African Americans at Increased Risk for Eye Diseases

https://yoursightmatters.com/african-americr-eye-diseases/

There are many diseases and conditions to which African Americans are more prone, such as diabetes, asthma, cancer, stroke, hypertension, lung disease and eye disease.  Here are some common conditions that affect the eyes:

Cataracts
Cataracts are a clouding of the lens of the eye. African Americans are 1.5 times more likely to develop cataracts than the general population and five times more likely to develop related blindness.

Glaucoma
Glaucoma refers to a family of diseases that affect the optic nerve and cause vision loss. African Americans are five times more likely than whites to develop glaucoma and four times more likely to develop related blindness.

Diabetes
African American adults are twice as likely as non-Hispanic whites to be diagnosed with diabetes and twice as likely to develop and die from diabetes-related complications. Diabetes can cause diabetic retinopathy, a condition that can lead to retinal damage and permanent vision loss.

Hypertension
Even though hypertension may not seem to be related to the eyes, high blood pressure can cause vision problems and vision loss. African American adults are more likely to be diagnosed with hypertension but less likely to have the condition under control (Source: Vision Problems).




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Eyes of Africa: The Genetics of Blindness

https://h3africa.org/index.php/consortium/projects/adeyinka-ashaye/



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African eye worm is worse than it looks: new study shows that the disease leads to increased mortality

October 22, 2016

https://www.dndi.org/2016/media-centre/press-releases/african-eye-worm-study-shows-disease-leads-to-increased-mortality/



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African Trypanosomiasis (African Sleeping Sickness)

https://wwwnc.cdc.gov/travel/diseases/african-sleeping-sickness-african-trypansosomiasis

African trypanosomiasis, also called African sleeping sickness, is a parasitic disease spread by the tsetse fly. Symptoms include fatigue, high fever, headaches, and muscle aches. If the disease is not treated, it can cause death.


Who is at risk?

Travelers who go to sub-Saharan Africa are at risk (see map). Travelers who plan to spend a lot of time outdoors or who go to game parks are at increased risk.



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Recognize These Common Eye Conditions

https://www.onhealth.com/content/1/common_eye_conditions


Glaucoma
Cataracts
Age-Related Macular Degeneration (AMD)
Retinal Detachment
Conjunctivitis (Pink Eye)
Uveitis
Eye Allergies
Sty (Stye)
Keratoconus
Blepharitis
Chalazion (Eyelid Cyst)
Corneal Ulcer
Diabetic Retinopathy
Floaters



----------------------------



Study: Eye-Socket Condition Thought Extinct is Actually Widespread

May 19, 2016

https://news.chass.ncsu.edu/2016/05/19/skull-condition-thought-extinct-is-actually-widespread/

Some forensic anthropologists thought the skull condition called cribra orbitalia (CO) was a thing of the past. However, new research from NC State and the University of the Witwatersrand finds that it not only still exists, but is fairly common in both North America and South Africa.

CO is a condition in which the bone inside the eye sockets becomes porous. It is not known to cause any adverse health effects, but is generally regarded as being caused by iron deficiency anemia. It has traditionally been used by anthropologists to assess diet and health in prehistoric populations. For example, the presence of CO could tell researchers that a population was not getting a sufficiently varied diet.

“But there’s been a lot of debate about the prevalence of CO in modern populations, with some saying it had effectively disappeared,” says Ann Ross, a professor of forensic anthropology at NC State and co-author of a paper on the work. “We wanted to know if CO was still extant and, if so, how common it is in modern populations, relative to earlier eras.”

For this study, the researchers looked at modern, historic and prehistoric human remains from South Africa, North Carolina and the Western Hemisphere Database. Altogether, the researchers evaluated data on 844 skulls: 245 prehistoric, 381 historic (as recent as the early 20th century) and 218 modern.

Their findings were surprising: CO was not only present in modern populations, but that it was not even uncommon.

For example, they found that two of the five modern North American juvenile skulls evaluated in the study – 40 percent – had CO. And 15 of the 60 South African juveniles evaluated in the study – 25 percent – had CO.

“We thought we might see some CO, but not to the extent that we did,” said Ross, the director of the Forensic Sciences Institute at NC State. “The high rates may stem from the fact that these remains were part of forensic cases – there were often related to cases of homicide or neglect. These cases are not representative of health for all children.”

Overall, the researchers found that 12.35 percent of modern North Americans and 16.8 percent of modern South Africans, across all age groups, had CO.

Both rates are higher than their historic counterparts. Only 2.23 percent of historic South African skulls evaluated had CO, and only 6.25 percent of historic North American skulls. Even the prehistoric North American skulls had a lower rate of CO, at 11.86 percent.



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The African Eye Worm: A Case Report and Review

Abstract

Loiasis, caused by the filarial nematode Loa loa, is often asymptomatic but frequently manifests as episodic angioedema and periocular migration of adult worms. Hence also known as the eye worm. 1 It is rarely encountered in the United States among travelers and immigrants. This report describes a case of loiasis in a Cameroonian student seen at a US university clinic.

https://academic.oup.com/jtm/article/15/1/50/1849304



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Ophthalmologic Manifestations of Onchocerciasis

2018

https://emedicine.medscape.com/article/1204593-overview

Background

Onchocerciasis, commonly known as river blindness, is a vector-borne disease that affects millions of people in Africa, the Middle East, and South and Central America. This disease is caused by the filarial parasitic nematode Onchocerca volvulus, which is transmitted by the blackfly vector Simulium, which carries third-stage larvae.

Infection can lead to chronic skin disease, severe itching, and eye lesions that can progress to complete blindness. There are approximately 123 million people at risk for infection in 38 countries and at least 25



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USC study examines age and ethnicity differences in eye problems

2007

https://news.usc.edu/17337/USC-study-examines-age-and-ethnicity-differences-in-eye-problems/


In a study of more than 6,000 Los Angeles-area children—the largest study of its kind—researchers at the Keck School of Medicine found that both strabismus (commonly known as cross-eyed or wall-eyed) and amblyopia (often referred to as lazy eye) were more prevalent in older children than in younger children.

The study is currently available in the online edition of the journal Ophthalmology.

The population for this first phase of the Multi-Ethnic Pediatric Eye Disease Study (MEPEDS) was composed equally of African-American and Hispanic youngsters, ages six months to six years, who reside in the Los Angeles County community of Inglewood.

The overall prevalence of strabismus was 2.5 percent; while this finding remained constant regardless of gender or ethnicity, prevalence trended upward with increasing age.

The overall prevalence of amblyopia, which was 2.6 percent in both ethnic groups, similarly trended upward with age, although researchers concluded that this trending stabilizes by three years of age. As with strabismus, researchers found no difference when amblyopia results were stratified by gender.



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Treacher Collins syndrome



Epidemiology

TCS occurs in about one in 50,000 births in Europe. Worldwide, it is estimated to occur in one in 10,000 to one in 50,000 births.








https://en.wikipedia.org/wiki/Treacher_Collins_syndrome



------------------------------




Jacobsen syndrome

https://ghr.nlm.nih.gov/condition/jacobsen-syndrome

Jacobsen syndrome is a condition caused by a loss of genetic material from chromosome 11. Because this deletion occurs at the end (terminus) of the long (q) arm of chromosome 11, Jacobsen syndrome is also known as 11q terminal deletion disorder.

The signs and symptoms of Jacobsen syndrome vary considerably. Most affected individuals have delayed development, including the development of speech and motor skills (such as sitting, standing, and walking). Most also have cognitive impairment and learning difficulties. Behavioral problems have been reported, including compulsive behavior (such as shredding paper), a short attention span, and easy distractibility. Many people with Jacobsen syndrome have been diagnosed with attention-deficit/hyperactivity disorder (ADHD). Jacobsen syndrome is also associated with an increased likelihood of autism spectrum disorders, which are characterized by impaired communication and socialization skills.

Jacobsen syndrome is also characterized by distinctive facial features. These include small and low-set ears, widely set eyes (hypertelorism) with droopy eyelids (ptosis), skin folds covering the inner corner of the eyes (epicanthal folds [Picture]), a broad nasal bridge, downturned corners of the mouth, a thin upper lip, and a small lower jaw. Affected individuals often have a large head size (macrocephaly) and a skull abnormality called trigonocephaly, which gives the forehead a pointed appearance.

More than 90 percent of people with Jacobsen syndrome have a bleeding disorder called Paris-Trousseau syndrome. This condition causes a lifelong risk of abnormal bleeding and easy bruising. Paris-Trousseau syndrome is a disorder of platelets, which are blood cells that are necessary for blood clotting.

Other features of Jacobsen syndrome can include heart defects, feeding difficulties in infancy, short stature, frequent ear and sinus infections, and skeletal abnormalities. The disorder can also affect the digestive system, kidneys, and genitalia. The life expectancy of people with Jacobsen syndrome is unknown, although affected individuals have lived into adulthood.




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A modified staged surgical intervention for blepharophimosis-ptosis-epicanthus inversus syndrome: 125 cases with encouraging results.

2013

https://www.semanticscholar.org/paper/A-modified-staged-surgical-intervention-for-125-Song-Jia/d0c736d05ced3226cf611e35c2a9e44c4faa8112



---------------------------


Blepharophimosis

https://en.wikipedia.org/wiki/Blepharophimosis

Blepharophimosis is a congenital anomaly in which the eyelids are underdeveloped such that they cannot open as far as usual and permanently cover part of the eyes.


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Blepharophimosis, ptosis, and epicanthus inversus syndrome

https://ghr.nlm.nih.gov/condition/blepharophimosis-ptosis-and-epicanthus-inversus-syndrome

 


---------------------------

10 - Oculoplastics

https://flylib.com/books/en/3.283.1.16/1/


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 Whites have a More Robust Hypothalamic-Pituitary-Adrenal Axis Response to a Psychological Stressor than Blacks


2007

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253947/



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AFRICAN AMERICANS HAVE A GREATER SENSITIVITY TO ALPHA1-ADRENOCEPTOR-MEDIATED VENOCONSTRICTION COMPARED TO CAUCASIANS


2013

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627527/


----------------------


INCIDENCE OF NORMAL PINEAL GLAND CALCIFICATION IN SKULL ROENTGENOGRAMS OF BLACK AND WHITE AMERICANS

1974

https://www.ajronline.org/doi/10.2214/ajr.122.3.503



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Facial pain. I. A prospective survey of 1052 patients with a view of: definition, delimitation, classification, general data, genetic factors, and previous diseases

1990

https://pubmed.ncbi.nlm.nih.gov/2077847/



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Differences in Pain Coping Between Black and White Americans: A Meta-Analysis

2016

https://pubmed.ncbi.nlm.nih.gov/26804583/


----------------------



Neural and sociocultural mediators of ethnic differences in pain

2020

https://www.nature.com/articles/s41562-020-0819-8?proof=t

Abstract

Understanding ethnic differences in pain is important for addressing disparities in pain care. A common belief is that African Americans are hyposensitive to pain compared to Whites, but African Americans show increased pain sensitivity in clinical and laboratory settings. The neurobiological mechanisms underlying these differences are unknown. We studied an ethnicity- and gender-balanced sample of African Americans, Hispanics and non-Hispanic Whites using functional magnetic resonance imaging during thermal pain. Higher pain report in African Americans was mediated by discrimination and increased frontostriatal circuit activations associated with pain rating, discrimination, experimenter trust and extranociceptive aspects of pain elsewhere. In contrast, the neurologic pain signature, a neuromarker sensitive and specific to nociceptive pain, mediated painful heat effects on pain report largely similarly in African American and other groups. Findings identify a brain basis for higher pain in African Americans related to interpersonal context and extranociceptive central pain mechanisms and suggest that nociceptive pain processing may be similar across ethnicities.

 




--------------------------------------------


'People were scared of me, they would start running': African girl who had rare brain surgery in Atlanta to remove giant tumor is now training to become a doctor treating deformities

https://www.dailymail.co.uk/news/article-3574703/People-scared-start-running-African-girl-rare-brain-surgery-Atlanta-remove-giant-tumor-training-doctor-treating-deformities.html



-----------------------------------------------




Dmanisi skulls

https://en.wikipedia.org/wiki/Dmanisi_skulls

The Dmanisi skulls are a set of hominin fossils (five crania and four mandibles) from the archaeological site near Dmanisi, Georgia. They were discovered in excavations at the site between 1991 and 2005. Dated to approximately 1.85-1.75 Ma, these fossils may morphologically represent the populations of hominins that initially emigrated out of Africa. Their small brain size, primitive skeletal architecture, and range of variation has been a point of debate for their taxonomic status. The fossil hominins have been described as exhibiting similarity to Homo ergaster, Homo georgicus, and are classified as either Homo georgicus, or as a subspecies of Homo erectus, Homo erectus georgicus.



------------------------------

 

 Cyclopia

https://en.wikipedia.org/wiki/Cyclopia


-----------------------


Coronal Synostosis Facts

https://nexusneurosurgery.com/coronal-synostosis-facts-and-photos-copy-copy/


----------------------


Cutis verticis gyrata

https://en.wikipedia.org/wiki/Cutis_verticis_gyrata


---------------------


The Vibrant Life Of Rocky Dennis, The Boy Whose Rare Deformity Inspired The Film ‘Mask’

2020

https://allthatsinteresting.com/rocky-dennis


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Early postnatal cranial vault reduction and fixation surgery for severe hydrocephalic macrocephaly

2018

https://thejns.org/pediatrics/view/journals/j-neurosurg-pediatr/21/5/article-p486.xml


------------------------------


Genetic disorders associated with macrocephaly

2008

https://onlinelibrary.wiley.com/doi/10.1002/ajmg.a.32434



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Ancient DNA puts a face on the mysterious Denisovans, extinct cousins of Neanderthals

2019

https://www.sciencemag.org/news/2019/09/ancient-dna-puts-face-mysterious-denisovans-extinct-cousins-neanderthals



------------------------------------------------




Homo erectus - A Bigger, Smarter, Faster Hominin Lineage

About two million years ago, a new set of fossils began to appear in the human fossil record. Designated as Homo erectus, they show evidence of increases in both body size and brain size.

https://www.nature.com/scitable/knowledge/library/homo-erectus-a-bigger-smarter-97879043/


Figure 1: Map of Homo erectus fossil localities.


Date (mya)     Locality     Key Fossils
1.9 – 1.2     Koobi Fora, Kenya     WT 15000 (Nariokotome), ER-3733, ER-3883
1.9 – 0.7     Olduvia Gorge, Tanzania     OH 9, OH 12
1.8 – 1.7     Dmanisi, Georgia     D3444, D2700, D2280, D2282
1.8 – 1.6     Swartkrans, South Africa     SK 847
1.8 – 0.9     Sangiran/Trinil, Indonesia     Trinil 2, Mojokerto, Sangiran 17, Sangiran 2
1.0 – 0.8     Ceprano, Italy     Ceprano 1
0.8 – 0.4     Zhoukoudian, China     ZKD E1, D1, L1, L2, H3
0.8 – 0.6     Bodo, Ethiopia     Bodo
0.6 – 0.3     Atapuerca, Spain     Sima de los huesos (numerous)
0.3 – 0.1     Jinniushan, China     Jinniushan
0.2 – 0.05     Ngandong, Indonesia     Ngandong 1, 9, 10, 11

Table 1: Key Homo erectus fossil sites. A partial list of key Homo erectus fossil localities, and some of the key specimens preserved at each. Exact dates are difficult to obtain for many of these localities, so the above dates represent best approximate ranges. In some cases, such as Olduvai Gorge and Koobi Fora, fossils have been recovered from many individual localities within the area, spanning a large range of dates.



--------------------------------------




Scientists Have Found the Oldest Known Human Fossils

The 300,000-year-old bones and stone tools were discovered in a surprising place—and could revise the history of our species.

https://www.theatlantic.com/science/archive/2017/06/the-oldest-known-human-fossils-have-been-found-in-an-unusual-place/529452/



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Do pigmentation and the melanocortin system modulate aggression and sexuality in humans as they do in other animals?

2012

https://www.sciencedirect.com/science/article/pii/S0191886912000840


----------------------------------------



What Can We Learn From Homo naledi’s Skull?

September 17, 2015
  
After the excitement of Homo naledi’s discovery and extraction from deep in a narrow cave in South Africa, and the implication that these non-humans may have intentionally carried their dead deep into the earth, we are left with the bones themselves, what they tell us about these creatures, and what new questions they inspire. These...

https://blog.nationalgeographic.org/2015/09/17/what-can-we-learn-from-homo-naledis-skull/



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Homo Naledi - New Questions On Human Evolution

Jul 13, 2020

https://www.youtube.com/watch?v=OgBJmdpqWsU

 

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Homo naledi and Pleistocene hominin evolution in subequatorial Africa

May 9, 2017

https://elifesciences.org/articles/24234




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Homo erectus , our ancient ancestor

https://www.nhm.ac.uk/discover/homo-erectus-our-ancient-ancestor.html


Reconstruction of Turkana Boy, the approximately 1.5-million-year-old, nearly complete skeleton discovered in Kenya. He was only about nine years old and already 1.6m tall. This reconstruction by Élisabeth DaynĂšs is on display at the MusĂ©e National de PrĂ©histoire in France. © Wolfgang Sauber, licensed under CC BY-SA 4.0, via Wikimedia Commons.




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  (We can see that Neanderthals and Humans both have lighter skin and darker skin versions.
Did the white skinned Neanderthals or the black skin Neanderthals exist first).




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Europeans did not inherit pale skins from Neanderthals (Debated)

26 September 2012

https://www.newscientist.com/article/dn22308-europeans-did-not-inherit-pale-skins-from-neanderthals/


The people who built Stonehenge 5000 years ago probably had the same pallid complexion of many modern inhabitants of the UK. Now it seems that the humans occupying Britain and mainland Europe only lost the darker skins of their African ancestors perhaps just 6000 years earlier, long after Neanderthals had died out. The finding confirms that modern Europeans didn’t gain their pale skin from Neanderthals – adding to evidence suggesting that European Homo sapiens and Neanderthals generally kept their relationships strictly platonic.

There is a clear correlation between latitude and skin pigmentation: peoples that have spent an extended period of time at higher latitudes have adapted to those conditions by losing the skin pigmentation that is common at lower latitudes, says Sandra Beleza at the University of Porto in Portugal. Lighter skin can generate more vitamin D from sunlight than darker skin, making the adaptation an important one for humans who wandered away from equatorial regions.

Those wanderings took modern humans into Europe around 45,000 years ago – but exactly when the European skin adapted to local conditions had been unclear.


Three genes

Beleza and her colleagues studied three genes associated with lighter skin pigmentation. Although the genes are found in all human populations, they are far more common in Europe than in Africa, and explain a significant portion of the skin-colour differences between European and west African populations.

By analysing the genomes of 50 people with European ancestry and 70 people with sub-Saharan African ancestry, Beleza’s team could estimate when the three genes – and pale skin – first became widespread in European populations. The result suggested that the three genes associated with paler skin swept through the European population only 11,000 to 19,000 years ago.

“The selective sweeps for favoured European [versions of the three genes] started well after the first migrations of modern humans into Europe,” says Beleza.

The finding agrees with earlier studies suggesting that modern humans did not lose their dark skins immediately on reaching Europe, says Katerina Harvati at the University of TĂŒbingen in Germany. “[The new study] is interesting because it suggests a very late differentiation of skin pigmentation among modern humans,” she says.

An earlier analysis of ancient DNA in 40,000 and 50,000-year-old Neanderthal bones, respectively from Spain and Italy, suggested that our extinct cousins had light-coloured skin and reddish hair in their European heartland. But the Neanderthals went extinct around 28,000 years ago – long before modern humans in Europe gained a pale skin. Evidently Neanderthals did not pass these useful local adaptations on to modern humans, despite genetic evidence that the two species interbred.
Middle Eastern contact

That might seem unusual given that the two species lived cheek-by-jowl in Europe for several thousand years. But it makes sense if the interbreeding evident in the genes occurred in the Middle East, where modern humans and Neanderthals first met, says Chris Stringer at the Natural History Museum, London.

In that region, Neanderthals may have had darker skins, explaining why our species did not gain a pale skin after interbreeding with them. Indeed, a study earlier this year of ancient DNA suggested that Neanderthals living in what is now Croatia had dark skin and brown hair.

“Neanderthal skin colour was probably variable, as might be expected for a large population spread out over a large territorial expanse,” says Harvati.



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 Humans Still Evolving as Our Brains Shrink

2009

https://www.livescience.com/7971-humans-evolving-brains-shrink.html



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Whites have a More Robust Hypothalamic-Pituitary-Adrenal Axis Response to a Psychological Stressor than Blacks


2007

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253947/


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 AFRICAN AMERICANS HAVE A GREATER SENSITIVITY TO ALPHA1-ADRENOCEPTOR-MEDIATED VENOCONSTRICTION COMPARED TO CAUCASIANS


2013

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627527/


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 Rates of Molecular Evolution Suggest Natural History of Life History Traits and a Post-K-Pg Nocturnal Bottleneck of Placentals

2017

https://www.cell.com/current-biology/pdfExtended/S0960-9822(17)31081-3



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List of examples of convergent evolution

May 2017

https://www.wikiwand.com/en/List_of_examples_of_convergent_evolution



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Platypus ancestor had teeth but inferior electro-sense

10-13-2016

https://cosmosmagazine.com/palaeontology/platypus-ancestor-had-teeth-but-less-developed-sixth-sense


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The pathology of vitamin D deficiency in domesticated animals: An evolutionary and comparative overview

Dec 2018

https://www.sciencedirect.com/science/article/pii/S1879981717301213



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Strong biomechanical relationships bias the tempo and mode of morphological evolution

2018

http://www.marthamunoz.com/uploads/2/3/4/5/23454312/munoz_2018_elife.pdf



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 'Red Deer Cave people' may be new species of human

2012

Stone age remains of people with a penchant for home-cooked venison could represent a new human evolutionary line

The fossilised remains of stone age people recovered from two caves in south west China may belong to a new species of human that survived until around the dawn of agriculture.

The partial skulls and other bone fragments, which are from at least four individuals and are between 14,300 and 11,500 years old, have an extraordinary mix of primitive and modern anatomical features that stunned the researchers who found them.

Named the Red Deer Cave people, after their apparent penchant for home-cooked venison, they are the most recent human remains found anywhere in the world that do not closely resemble modern humans.

The individuals differ from modern humans in their jutting jaws, large molar teeth, prominent brows, thick skulls, flat faces and broad noses. Their brains were of average size by ice age standards.

https://www.theguardian.com/science/2012/mar/14/red-deer-cave-people-species-human



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'All bets now off' on which ape was humanity's ancestor

8-28-2019

https://www.bbc.com/news/science-environment-49486980



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Differentiation of modern sub-Saharan African populations: craniometric interpretations in relation to geography and history

2004

https://journals.openedition.org/bmsap/3873




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Racial differences in skull shape.

2008

Firstly, the mostly obvious difference is that the Caucasoid top skull has a very flat profile, while the bottom skull is ‘prognathic’, meaning it’s jaws protrude out. Although not obvious from this image, the nose aperture of the Caucasian skull has a narrower triangle shape; with a longer, thinner bony protrusion at the point where the nose comes out from between the eyes (nuchal ridge). Caucasian skulls also posess a nasil sill (unless you see this shown, no explanation will make sense), Asian and African skulls don’t.

 

https://mathildasanthropologyblog.wordpress.com/2008/07/23/racial-differences-in-skull-shape/


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 This could be why our eyebrows evolved

April 9, 2018

https://www.cnn.com/2018/04/09/health/eyebrows-hominin-human-evolution/index.html



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Maxillary Arch Size and Shape in American Blacks and Whites

https://www.angle.org/doi/pdf/10.1043/0003-3219%282000%29070%3C0297%3AMASASI%3E2.0.CO%3B2


Benjamin G. Burris, BAa; Edward F. Harris, PhDb

Abstract:American  blacks have larger teeth than whites, but they less frequently exhibit crowding—apparently because of larger arch dimensions. This study quantified differences in arch size and shape inthese  2  constituents  of  the  US  population.  Eighteen  dental  and  bony  landmarks  were  digitized  from themaxilla of each of 332 subjects with permanent, intact dentitions, proportionately divided between blacksand  whites,  men  and  women.  Linear,  angular,  and  area  measurements  were  computer-generated.  Archwidths averaged 10% greater in blacks than whites, and mesiodistal arch depths had a greater difference,at 12%. Blacks, with a more square palate and significantly larger palatal index, were distinguished fromwhites primarily by greater intercanine and interpremolar widths. Arch perimeter was greater in blacks by 8%, and cross-sectional area of the arch was 19% greater in blacks than whites, so blacks and whites differsubstantially for these parameters not only in size, but in shape as well. These differences are relevant inprosthodontics and orthodontics since individualization of treatment leads to more effective treatment byworking  within  the  patient’s  natural  arch  form  instead  of  making  patients  fit  a  single  standard. 




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Racial Identification in the Skull and Teeth

6-21-2011

Blumenfeld: Racial Identification in the Skull and Teeth

https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=1137&context=totem

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Ancient Mutation Explains Missing Wisdom Teeth

2013

https://www.livescience.com/27529-missing-wisdom-teeth.html

 


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5 Countries with the Worst Oral Health

https://www.dmdtoday.com/news/5-countries-with-the-worst-oral-health

 4. Bolivia

This country nestled in the middle of South America has some of the worst oral health in the region. Twelve-year-olds have an average of four decayed, missing, or filled-in teeth. A study also suggests that only 50 percent of students own a toothbrush.

3. Australia

This Western country may come as a surprise on this list, but its statistics earn it the number 3 spot. Nearly half of all 6-year-olds have tooth decay in their baby teeth. Aboriginal and Torres Strait Islander children between ages four and 15 are more likely to experience dental disease.

2. India

This subcontinent with over a billion people was bound to make the list. India’s National Oral Health Program reports that 95 percent of all adults have gum disease, and 50 percent of citizens don’t use a toothbrush. The program also noted that 70 percent of children under the age of 15 have dental caries.

1. Philippines

This island nation located in between the South China Sea and the Philippine Sea takes the cake (literally and figuratively) of the worst oral health in the world. The Philippines College of Dentistry found that nearly 90 percent of Filipinos suffer from tooth decay. Another astonishing finding is that nearly 100 percent of children between 3 and 5 years old have cavities. For a country that is less than half the size of Texas, those are some staggering numbers!


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Color/race inequalities in oral health among Brazilian adolescents

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2009000300003


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Unknown lung disease in China

With an unknown lung disease apparently spreading in China, could there be a new outbreak akin to SARS? Not necessarily. Authorities have yet to identify it. And many respiratory illnesses are caused by viruses.

https://www.dw.com/en/unknown-lung-disease-in-china/a-51902586


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Race, ethnicity and lung function: A brief history


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631137/


Over the past century, the spirometer has gained widespread use across the world for the diagnosis and management of many respiratory diseases in both specialist and primary care settings. Chronic obstructive respiratory disease, a major cause of disability and mortality, is defined by spirometry. The great variability in lung function measurements over time, space, within countries, within individuals, among groups and among spirometers, however, has complicated the interpretation of ‘normal’. Temporal trends can be quite dramatic, with lung function increasing in certain populations and decreasing in others during the same time period. Since the 1960s, much effort has been expended to standardize the many sources of variability.

One outcome of global standardization projects is the common practice of ‘race correction’, also called ‘ethnic adjustment’. Most commercially available spirometers internationally ‘correct’ or ‘adjust’ for race in one of two ways: by using a scaling factor for all people not considered to be ‘white’; or by applying population-specific norms. To enable the spirometer, the operator must select the race of an individual, as well as indicate their age, sex/gender and height. How race (or population) is determined varies, with most operators either asking patients to self-identify or ‘eyeballing it’. Interviews with users of the spirometer indicate that many operators are unaware that they are automatically activating race correction when they select a patient’s race. Because ‘correction’ is programmed into the spirometer by the manufacturer, it can be difficult to disable.

Despite attempts by international organizations, the approach to ‘correction’ or ‘adjustment’ is not always consistent. The Joint Working Party of the American Thoracic Society/European Respiratory Society recommends the use of race- and ethnic-specific references values when available. Alternatively, they recommend correction factors. In the United States (US), spirometers use either correction factors of 10% to 15% for individuals labelled ‘black’ and 4% to 6% for people labelled ‘Asian’, or population-specific standards, usually those derived from the third US-based National Health and Nutrition Examination Survey for ‘Caucasians’, African Americans and Hispanics. In Europe, correction factors are used. Canada continues to negotiate the delicate balance between international and local standards. The United Kingdom-based Vitalograph spirometer programs population-specific standards into spirometers marketed in North America, whereas they use a correction factor for devices marketed in Europe.


RACIALIZING THE SPIROMETER

What is the history of this practice? How did the idea of racial and ethnic difference in lung capacity become so widely accepted such that correction factors are actually programmed into the spirometer? The notion that black and white lungs differ has a long history dating to the early years of the US slavery-based republic. In his influential Notes on the State of Virginia, former president and leading Enlightenment intellectual Thomas Jefferson featured lung differences between slaves and white colonists. Among the many physical distinctions that Jefferson described to justify the condition of slaves in the republic, one was “a difference of structure in the pulmonary apparatus”. Jefferson’s ideas about lungs would remain, however, in the realm of philosophical speculation without empirical foundation until the second half of the 19th century.

Interest in modern spirometers surged in Europe in the 1840s after John Hutchinson, a London-based physician, published several studies describing the technical features of the spirometer and its potential applications for monitoring the fitness of the police and armed forces, and life insurance applicants and for diagnosing tuberculosis, the great scourge of 19th-century industrializing nations. In a period of great enthusiasm for precision instrumentation and experimental interest in the functional features of the lungs, Hutchinson avidly promoted his innovation, naming the spirometer, delineating “vital capacity” into discrete compartments, adapting the instrument to large-scale studies, and advocating for his technology to London’s prestigious scientific societies.

Hutchinson faced the same dilemma future researchers would encounter in ordering the wide variability in lung function. While he was most excited about his discovery that the relationship between height and lung capacity demonstrated what he considered to be “a general law of nature”, height did not completely account for the variability he observed. To capture more fully the potential he envisioned for his instrument, Hutchinson further classified lung capacity measurements according to occupation. However, occupational categories would remain an organizing principle for research on lung capacity measurements only into the early 20th century in Britain.

Knowledge of the spirometer spread quickly and Hutchinson’s innovations were adopted within a few years in Germany and North America, where researchers worked to further refine its technical details and uses. Perhaps the most significant experiments for the future of spirometry were those of plantation physician and slaveholder Samuel Cartwright in the US south. Drawing explicitly on Jefferson’s interpretive framework, Cartwright built his own spirometer to study difference in lung capacity in slaves and whites, and to quantify it precisely. According to Cartwright, “the deficiency in the negro” was “20 per cent”. Defining difference as ‘deficiency’, Cartwright established race as a key organizing principle of lung function measurements in the US.

Jefferson’s philosophical musings were to capture an even more solid empirical foundation in the 1860s when racial research examining lung capacity shifted to the northern US. In 1864, the US Sanitary Commission asked Benjamin Apthorp Gould to head a massive anthropometric survey of black and white soldiers at the end of the Civil War. Over several years, field workers collected detailed data regarding bodily characteristics of soldiers, which Gould synthesized in his 1869 Investigations in the Military and Anthropological Statistics of American Soldiers. For unclear reasons, he chose to devote an entire chapter to describing lung capacity – measured using a spirometer– according to race. Without any adjustment for height or age, or attention to working and living conditions of newly emancipated slaves, Gould reported that “full blacks” had lower lung capacity than “whites”. The results were neither surprising to Gould nor in need of careful explanation. Using ostensibly neutral language, he wrote:

    The great difference of the mean volume found for the black race from that which seems to belong to the whites, cannot fail to attract attention at the first glance. Its bearings are perhaps better manifested by the more detailed tabulations which will follow.

Nearly 30 years later, Frederick Hoffman, chief statistician for Prudential Life Insurance Co. would turn to Gould’s data to make broad claims about the lack of fitness of African Americans for freedom. According to Hoffman, “the smaller lung capacity of the colored race is in itself proof of an inferior physical organism”.

There were important dissenting views at the time. Notably, leading African American intellectuals WEB DuBois and Kelly Miller wrote trenchant critiques of Hoffman’s arguments over the inferiority of the “negro”. These critiques, however, failed to alter the narratives of difference embedded in lung capacity measurements, which would gain further scientific foundation in the 20th century.

Beginning in the US in the 1920s, during a period when eugenic policies rooted in hereditarianism were popular, research documenting racial difference in lung function became an even broader global enterprise. In most studies, whites had higher lung capacity than blacks, Chinese or Indians; explanations for findings centred on innate difference. For example, Wilson and Edwards published the first set of spirometry-based lung function standards according to race in 1922, speculating that difference could be due to “a possible racial factor”. By 1925, JE Myers published his reference handbook for clinicians, in which he reported differences among whites, blacks, Chinese and Filipinos as unquestioned fact. Thus, the idea of racial difference in lung capacity, first proposed by Jefferson and further supported by Cartwright and Gould in the US, was firmly established by the early 20th century as an ostensible fact. Future research would build on this framework.

During the 1960s – and continuing to the present – interest in racial difference expanded to numerous populations across the world and researchers focused on developing standards for what they considered to be distinct populations. For historically specific reasons, the most influential studies coming from the US centred on black-white differences. The consequential technological innovation of a ‘scaling factor’ for blacks in 1974, however, was the result of the collaboration between Charles Rossiter of the Pneumoconiosis Unit in South Wales and Hans Weill of Tulane Medical School in New Orleans, Louisiana.

A large proportion of the literature used an explanatory framework that emphasized innate or anthropometric difference. For the most part, researchers assumed racial identities to be straightforward. There was one notable exception. In an article important to the history of spirometry, South African researchers questioned the interpretations of difference, arguing that previous research failed to account fully for social conditions. North American and European researchers, however, failed to cite these articles and the idea that racial difference was innate remained firmly entrenched in the pulmonology literature.

As demonstrated in a recent systematic review, the exclusive racial framework continued into the 21st century. Rather than a fluid, historically contingent system of classification, researchers treated race as a stable category, uncomplicated by social class, sex or geographical context. In fact, researchers only defined how they assigned individuals to racial categories in 17.3% of the articles; 94% of the articles failed to include any measures of social class. Most recently, genomics studies have reinforced, rather than questioned, race-based models. Gould continues to be cited to the present day in prestigious US journals.

CONCLUSION

How can this brief history help us analyze the contemporary dilemmas in lung function research as it pertains to the use of race and ethnicity in pulmonary function tests? At the very least, the idea that people labelled ‘white’ naturally have higher lung capacity than other races throughout the world should be approached with some skepticism.

The history of lung function suggests that we should be approaching spirometry differently. Rather than using race in a routinized way that reflects assumptions of genetic difference, we should be asking different research questions about the lived experience of race. Research and clinical practice needs to devote more careful attention to the social nature of racial and ethnic categories and draw on more complex explanatory frameworks that incorporate disproportionate exposures to toxic environments, differential access to high-quality care and the daily insults of racism in every sphere of life that manifest biologically. Across the globe, there is a continuum of human phenotypic and genetic variation that cannot be apportioned into discrete categories. By featuring race with only marginal attention to the intersection of race and social class, we risk ignoring the complex and dynamic relationship of lung function and the environment. It is well-established that lower forced vital capacity is associated with social conditions, notably poverty. The specific details of how social class and race influence lung function physiologically, however, remains to be determined. It is time to rethink the problematic practice of race correction in light of this history.




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Different Craniofacial Characteristics Predict Upper Airway Collapsibility in Japanese-Brazilian and White Men

2016

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944782/

Abstract


Background

OSA pathogenesis is complex and may vary according to ethnicity. The anatomic component predisposing to OSA is the result of the interaction between bony structure and upper airway soft tissues and can be assessed using passive critical closing pressure (Pcrit). We hypothesized that Japanese-Brazilians and whites present different predictors of upper airway collapsibility, suggesting different causal pathways to developing OSA in these two groups.


Methods

Male Japanese-Brazilians (n = 39) and whites (n = 39) matched for age and OSA severity were evaluated by full polysomnography, Pcrit, and upper airway and abdomen CT scans for determination of upper airway anatomy and abdominal fat, respectively.


Results

Pcrit was similar between the Japanese-Brazilians and the whites (−1.0 ± 3.3 cm H2O vs −0.4 ± 3.1 cm H2O, P = .325). The Japanese-Brazilians presented smaller upper airway bony dimensions (cranial base, maxillary, and mandibular lengths), whereas the whites presented larger upper airway soft tissue (tongue length and volume) and a greater imbalance between tongue and mandible (tongue/mandibular volume ratio). The cranial base angle was associated with Pcrit only among the Japanese-Brazilians (r = −0.535, P < .01). The tongue/mandibular volume ratio was associated with Pcrit only among the whites (r = 0.460, P < .01). Obesity-related variables (visceral fat, BMI, and neck and waist circumferences) showed a similar correlation with Pcrit in the Japanese-Brazilians and the whites.


Conclusions

Japanese-Brazilians and whites present different predictors of upper airway collapsibility. Although craniofacial bony restriction influenced Pcrit only in the Japanese-Brazilians, an anatomic imbalance between tongue and mandible volume influenced Pcrit among the whites. These findings may have therapeutic implications regarding how to improve the anatomic predisposition to OSA across ethnicities.





Figure 1

A-D, Representative sagittal and volumetric CT scan reconstructions of a Japanese-Brazilian (A and C) and a white (B and D) subject matched for age and OSA severity. Cephalometric landmarks used are shown in A and B. Volumetric reconstructions of the tongue and mandible are shown in C and D. The Japanese-Brazilian subject was 49 years old with a BMI of 28 kg/m2 and an apnea-hypopnea index (AHI) of 60 events/h. The white subject was 46 years old with a BMI of 30 kg/m2 and an AHI of 60 events/h. The Japanese-Brazilian subject presented smaller cranial base dimensions (NS and NSBa) (A), suggesting increased bony restriction, but smaller tongue volume and tongue/mandibular volume ratio (C), suggesting a better balance between bony and soft tissue, as compared with the white subject (B and D). Pharyngeal critical closing pressure (Pcrit) was similar (−0.4 and −0.2 cm H2O, Japanese-Brazilian and white, respectively). A = point A; ANS = anterior nasal spine; B = point B; Ba = cranial base; Cd = medial condylar point of the mandible; Ep = epiglottis base; H = hyoid bone; In = incisors occlusion; MP = mandibular plane; MV = mandibular volume; N = nasion; NS = cranial base length; NSBa = cranial base angle; PNS = posterior nasal spine; Pog = pogonion; S = sella; TL = tongue length; TV = tongue volume; TV/MV = tongue/mandibular volume ratio.




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Which oropharyngeal factors are significant risk factors for obstructive sleep apnea? An age-matched study and dentist perspectives

 2016

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944919/


Abstract


Objective

Obstructive sleep apnea (OSA) is a common sleep breathing disorder. Untreated OSA may lead to a number of cardiovascular complications. Dentists may play an important role in OSA detection by conducting careful oral examinations. This study focused on the correlation of oral anatomical features in Thai patients who presented with OSA.


Methods

We conducted a prospective comparative study at a sleep/hypertension clinic and a dental clinic at Khon Kaen University in Thailand. Patients with OSA were enrolled in the study, along with age-matched patients with non-OSA (controls). Baseline characteristics, clinical data, and oropharyngeal data of all patients were compared between the two groups. Oropharyngeal measurements included tongue size, torus mandibularis, Mallampati classification, palatal space, and lateral pharyngeal wall area. Multivariate logistic regression analysis was used to identify the factors associated with OSA.


Results

During the study period, there were 156 patients who met the study criteria; 78 were patients with OSA and the other 78 were healthy control subjects. In the OSA group, there were 43 males with a mean age of 53 (standard deviation 12.29) years and a mean BMI of 30.86 kg/mm2. There were 37 males in the control group with a mean age of 50 (standard deviation 12.04) years and a mean BMI of 24.03 kg/mm2. According to multivariate logistic analysis, three factors were perfectly associated with OSA, including torus mandibularis class 6, narrow lateral pharyngeal wall, and Mallampati class 4. There were two other significant factors associated with having OSA, namely, BMI and Mallampati classification. The adjusted odds ratios (95% confidence interval) of these two factors were 1.445 (1.017, 2.052) and 5.040 (1.655, 15.358), respectively.

Conclusion

Dentists may play an important role in the detection of OSA in patients with high BMI through careful oropharyngeal examination in routine dental treatment. A large torus mandibularis, Mallampati class 4, and a narrow lateral pharyngeal wall are important anatomical risk factors for OSA.

Introduction

The prevalence of obstructive sleep apnea (OSA) has been reported to be 2%–4% in the general population.1 It is a contributing factor for cardiovascular diseases such as hypertension, coronary artery disease, and stroke, as well as for traffic accidents and poor quality of life.2–4 Diagnosis of OSA can be made using polysomnography in patients who have an apnea–hypopnea index of more than five events per hour. Obesity is a major risk factor for OSA. Other risk factors are oral abnormalities such as macroglossia and a narrow pharynx.5 Early detection and treatment of OSA have been shown to reduce the risk of cardiovascular diseases and, thus, death from heart diseases, and to reduce the frequency of strokes.

Dentists actually play an important role in OSA diagnosis and treatment. They see patients’ oral cavity in daily practice and can identify those who are at risk of OSA. In addition, oral appliances can be custom-made for OSA treatment. Several craniofacial factors have been reported to be important risk factors for OSA. Neck circumference of >17 inches (43.2 cm) in men and 16 inches (40.6 cm) in women increases the risk of OSA. Similarly, large tongue and Mal-lampati classification are also significant predictors of OSA. A small study from People’s Republic of China conducted with 15 patients with OSA showed that neck circumference and craniofacial measurements such as anterior superior hyoid to mandibular plane or the velum tip to the pharyngeal wall parallel to the Frankfurt horizontal were associated with OSA.6 These factors may require several landmarks and are not practical for clinical use. This study aimed to evaluate if any oropharyngeal parameters associated with OSA can be detected using methods that are more practical for a dentist.



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Macroglossia

Macroglossia is the medical term for an unusually large tongue. Severe enlargement of the tongue can cause cosmetic and functional difficulties in speaking, eating, swallowing and sleeping. Macroglossia is uncommon, and usually occurs in children. There are many causes. Treatment depends upon the exact cause.


https://en.wikipedia.org/wiki/Macroglossia


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Primary systemic amyloidosis presenting as macroglossia

2017 

http://www.saudijos.org/article.asp?issn=1658-6816;year=2017;volume=4;issue=2;spage=117;epage=121;aulast=Aluri

A 61-year-old female patient was presented to Surgery Department, Yashoda Hospitals, Malakpet, Hyderabad, with chief complaints of gradually progressive diffuse enlargement of the tongue for 6 months. On examination, she appeared to be in good general health, but his speech had been slurred ostensibly, due to tongue swelling. On clinical examination, the patient was found to be edentulous, with tongue grossly enlarged. No ulcerations or nodules were seen over the tongue surface. The patient is not a known case of hypertension, diabetes mellitus, or ischemic heart disease. Systemic examination was unremarkable.

An incisional biopsy was performed on the both lateral border and ventral aspect of the tongue and abdominal fat. Histopathological examination of Hematoxylin and Eosin (H and E)-stained sections revealed extracellular deposition of amorphous, eosinophilic hyaline-like material in the submucosal connective tissue, which appeared to be amyloid. To confirm the presence of amyloid, a special staining with Congo red was performed, which showed peach, red color on light microscopy, and apple green birefringence on polarized light microscopy. To rule out a systemic involvement, we performed a series of investigations[Figure 1].

Figure 1: Macroglossia and ventral, lateral aspect of tongue biopsy, and abdominal fat biopsy showing amorphous, eosinophilic hyaline-like material (blue color arrows)



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Relative rather than absolute macroglossia in patients with Down syndrome: Implications for treatment of obstructive sleep apnea

October 2008

https://www.researchgate.net/publication/23154765_Relative_rather_than_absolute_macroglossia_in_patients_with_Down_syndrome_Implications_for_treatment_of_obstructive_sleep_apnea


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Segmental tracheal dysplasia in a mixed breed dog

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1571127/


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Nasal Analysis and Anatomy: Anthropometric Proportional Assessment in Asians—Aesthetic Balance from Forehead to Chin, Part II

2015

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656157/


Abstract

Caucasians usually have reduction or correction rhinoplasty; however, Asian nasal surgery is mainly for augmentation rhinoplasty. Therefore, an Asian rhinoplasty should start with a precise understanding of ethnic anatomical differences. The authors summarize the anatomical characteristics of Asians to ensure the best results.

An Asian rhinoplasty can be a surgical challenge because of the diverse anatomy between different racial groups. Surgeons undertaking rhinoplastic surgery in non-Caucasian individuals need a broad understanding of ethnic-specific features.1 Asian aesthetic goals should be patient-tailored to the ethnicity and culture of the individual patient.2 Compared with Caucasians, Asians generally have a shorter, wider, and less-projecting nose, requiring augmentative and structural rhinoplasty, whereas reduction rhinoplasty and some form of lower lateral cartilage reduction is more popular in Caucasians with dorsal hump prominence.

Morphology Classification

There are many types of Asian nose morphologies.4 Three broad morphological types have been used to describe the spectrum of ethnic variations. The leptorrhine (“tall and thin”) nose is associated with Caucasian or Indo-European descent. The platyrrhine (“broad and flat”) nose is associated with African origins. And the mesorrhine (“intermediate”) nose has features intermediate between the leptorrhine nose and the platyrrhine nose. The “typical” Asian or Latino nose is commonly regarded as mesorrhine, with low radix, variable anterior dorsal projection, rounded and underprojected tip, and rounded nostrils.

Ethnic Variation

One of the main features of the nonoperated Asian nose is a more triangular shape on the frontal view. When assessing the Asian nose from the side view, it is common to see a nasal bridge that is lower in height when compared with a Caucasian nose. Anatomical features of Asians include thicker skin, weaker cartilages, less dorsal projection, rounder tip and alae, and a more-retrusive columella. Another common feature of the Asian nose is a flared nasal base, with wider-than-average nostrils.


External Soft Tissue Envelope

The anatomical structures of the nose can be categorized in groups by anatomical layers. Surgical dissection between these structural planes is critical to preserving the anatomical structures. External coverage of the nose is composed of the skin, subcutaneous tissue, fibromuscular layer, and perichondrium or periosteum.

Skin

The thickness and texture of the skin can have a significant effect on the result of the operation; therefore, it is important to evaluate patient skin characteristics during preoperative planning. Generally, nasal skin becomes more pliable and thinner in the upper portion, but tighter and more adherent in the lower portion.8 The mean skin thickness of the nasofrontal angle area is 1.25 mm—the thickest area. In contrast, the mean skin thickness of the rhinion is 0.6 mm—the thinnest area.9 Asian noses tend to have thicker skin and more abundant subcutaneous soft tissue than noses of Caucasians.8 Fibrofatty tissue is the dense structure that attaches to the underlying cartilage.10
Subcutaneous Layer

Four soft tissue layers are present between skin and the osseocartilaginous framework, consisting of the following:

    Superficial fatty layer panniculus

    The fibromuscular layer (nasal SMAS) is basically an extension of the superficial musculoaponeurotic system (SMAS). The SMAS becomes retracted on both sides in the case of disconnection due to careless surgery or trauma; bone or cartilage is placed underneath the location that may be exposed. Moreover, the nasal SMAS may be directly adhered to the the superficial fatty layer and scar tissue attached to the dermis.

    The deep fatty layer houses important vessels and a motor nerve, which are located at a shallow point. In surgery, it is easy and safe to elevate the external skin envelope at the lower portion of this deep layer of fat.

    Periosteum or perichondrium

Intrinsic and Extrinsic Nasal Musculature

The nasal musculature is involved in facial expression, the variable motion of the nose, and nasal cavity control during respiration. The muscles involved can be broadly classified into intrinsic muscles and extrinsic muscles. They function by interrelating partially with each other. All of the aforementioned nasal musculatures receive innervation from the zygomatic division of the facial nerve. The intrinsic muscles of the nose are the nasalis and its lower portion: the dilator naris or the levator alae. The external muscles of the nose are the procerus, the orbicularis, the depressor septi, and the levator labii alaeque nasi (Fig. 1). These muscles provide static support for the nose as well as the facial muscles.


There has been some debate on the function of the intrinsic muscles. Nonetheless, intrinsic muscle has an important role in maintaining the nasal airway. The nasal musculature can be generally classified into four groups based on function as shown in Table 1.8

Supporting Neurovasculature

Blood Supply

The blood supply of the nose consists of the facial artery, which is a branch of the external carotid artery, and the ophthalmic artery, which is a branch of the internal carotid artery and the internal maxillary artery (Fig. 2). They form various vascular arcades in the areas around the nose. The terminal pattern of each branch varies greatly depending on the patient. Nevertheless, many branches have overlapping territory. Hence, an interruption or a significant decrease in blood circulation rarely occurs, even if some of the branches are damaged. Blood is supplied to the midline from the branches on both sides of the nose in the form of dual perfusion. Some people have better perfusion on the left side, whereas others have it on the right side. The phenomenon is closely related to facial asymmetry. The extensive collateral blood supply of the nose makes an open rhinoplasty safe.

Bony Vault

The upper third of the nose is a bony vault formed by a pair of nasal bones and the frontal process of the maxilla. It is supported by the bony septum at midline (Fig. 4). This bony vault is linked to the nasal process of the frontal bone superiorly, the frontal process of maxilla laterally, and the upper lateral cartilage inferiorly. The posterior margin of the frontal process of the maxilla together with the lacrimal bone forms a lacrimal groove. The lacrimal sac is situated in this area. The junction between the caudal area of the nasal bone and the cephalic area of the upper lateral cartilage is referred to as the keystone area. The caudal area of the nasal bone and the cephalic area of the upper lateral cartilage are overlapped by 4 to 5 mm on average. In general, they overlap a shorter distance among Asians compared with Caucasians. The nasal bone length has a certain degree of variation. However, it is 25 mm on average among Caucasians.8 For Asians, the nasal bone is often short, small, or thick, and a fracture can occur without excessive manipulation. Thus, it is very important to identify the characteristics of the bony vault of a patient in the preoperative evaluation.



Alar Cartilage (Lower Lateral Cartilage)

Traditionally, the alar cartilage has been classified into two parts: medial crus and lateral crus.22 The two parts are connected by a dome segment. However, Sheen and Sheen22 added the concept of the middle crus to make it easier to understand dissection for tip plasty (Fig. 6). The reason why such classification is important is that complex and diverse shapes of middle crus have a very significant impact on the shape of the nasal lobule. Those cases in which the angle of domal divergence is 60 degrees or smaller are deemed normal. Those cases in which the aforementioned angle is 60 degrees or higher are deemed to have a broad nose. Of those, the cases in which the length of the middle crus dome segment is 4 mm or longer with a curved part and wide domal angle are deemed to have a boxy tip. In contrast, a bulbous tip is defined as follows: The dome segment serving as a meeting point of lateral crus and middle crus is not curved as sharply as a boxy tip; the curved shape is less sharp than the average level; and the widening angle of dome is wide.

The medial crus is classified into a footplate and a columella segment. The medial crura on both sides are attached to each other by a small amount of fibroareolar tissue. Between the two-sided medial crura and the two-sided middle crura lies dense fibrous connective tissue in a horizontal direction. Thus, the two-sided medial crura and the two-sided middle crura are firmly attached to each other. The thick part located at the very front of fibrous connective tissue is referred to as the interdomal ligament. The lateral crus is the largest component of the nasal lobule, which performs an important role in defining the shape of the anterosuperior portion of the ala nasi. The lateral crus is in direct contact with the dome segment of the middle crus in intorsion. On the lateral side, it is adjacent to the first cartilage of an accessory cartilage chain that is in contact with the pyriform aperture.8 The connection between the caudal edge of the upper lateral cartilage and the cephalic edge of the lateral crus of the alar cartilage is quite unique: The caudal edge of the upper lateral cartilage is curved just like the edge of a scroll toward the outside of the nose as is the edge of the cephalic edge scroll of the lateral crus of the alar cartilage, whose end is curved toward the inside of the nose. Thus, it is overlapped as though the former is hung onto the latter (scroll area). In most patients, these two cartilages are overlapped in this way, thereby improving the function of the internal nasal valve.

Sesamoid cartilages are located at the junction between the upper lateral cartilage and the lateral crus of the alar cartilage. It serves as a bearing so that the lateral crus can move smoothly above the upper lateral cartilage. They are connected by dense fibrous connective tissue. This fibrous connective tissue is adjacent to the perichondrium on the surface and the upper lateral cartilage and the alar cartilage lateral crus.

The accessory cartilage is a chain of several cartilages located in the lateral area rather than the lateral crus of the alar cartilage. They are not only interconnected with each other, but also with the lateral crus through the dense fibroareolar tissue. Hence, these cartilages function as if they are one single cartilage.8 Therefore, it is more important to have accessory cartilage than sesamoid cartilage for the shape of the nose. Alar cartilage is shorter among Asian people compared with Caucasian people. It is also weaker among Asian people; its supporting structures are weak. In addition, when the other soft tissues including the skin of that area are thick, the alar cartilage will be even weaker in terms of a supporting structure.

Nasal Septum

The nasal septum stands straight up at the midline to support the nasal dorsum. Moreover, it divides the nasal cavity into two spaces. The shape and width of the septum varies among different races. Nonetheless, it is shaped like an “I” when viewed on cross-section. It is shaped like a “T” when the edge of the dorsum of nasal septum is wide.25 The nasal septum consists of one septal cartilage and four bones that consist of the perpendicular plate of ethmoid, vomer, nasal crest of maxilla, and nasal crest of palatine bone (Fig. 7). For convenience sake, the nasal septum is subdivided into the bony septum, the cartilaginous septum, and the membranous septum.


Conclusions

Each race has a different nose shape. Caucasians usually have a narrow nose (leptorrhine), whereas African Americans have a flat nose (platyrrhine). Asians have intermediate features somewhere between these two races (mesorrhine). The following are anatomical considerations in the performance of an Asian rhinoplasty.

    The nasal dorsum is wide, low, and flat.

    The nose tip is low, wide, and rounded (bulbous tip): This is because the alar cartilage is small and both sides are separated from the nose tip.

    The skin of the nose tip and supratip area has a thick dermis and a subcutaneous layer. Also, it has an abundance of fibrofatty tissues. Moreover, sebaceous glands are highly developed.

    The nasolabial angle looks narrow when viewed from the side. Also, the ala is huge and bent caudally. The columella is relatively short, whereas the columella base is recessed cephalically.

    The nostril is splayed out horizontally when viewed from caudal side. Thus, the distance between alar base on both sides is far.

    The anterior nasal spine is hypoplastic.

    The alar cartilage is small and weak, making it difficult to project the nasal tip with alar cartilage suturing alone. Furthermore, it is also impossible for the alar cartilage to sustain the tip with the rhinoplasty approach that is conducted commonly among Caucasians.

    Nasal septal cartilage is very thin. Thus, it cannot be routinely utilized as an autogenous cartilage structural support graft.



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Diffuse panbronchiolitis


https://en.wikipedia.org/wiki/Diffuse_panbronchiolitis

Diffuse panbronchiolitis (DPB) is an inflammatory lung disease of unknown cause. It is a severe, progressive form of bronchiolitis, an inflammatory condition of the bronchioles (small air passages in the lungs). The term diffuse signifies that lesions appear throughout both lungs, while panbronchiolitis refers to inflammation found in all layers of the respiratory bronchioles (those involved in gas exchange). DPB causes severe inflammation and nodule-like lesions of terminal bronchioles, chronic sinusitis, and intense coughing with large amounts of sputum production.

The disease is believed to occur when there is susceptibility, or a lack of immune system resistance, to DPB-causing bacteria or viruses, caused by several genes that are found predominantly in individuals of East Asian descent. The highest incidence occurs among Japanese people, followed by Koreans. DPB occurs more often in males, and usually begins around age 40. It was recognized as a distinct new disease in the early 1960s, and was formally named diffuse panbronchiolitis in 1969.

If left untreated, DPB progresses to bronchiectasis, an irreversible lung condition that involves enlargement of the bronchioles, and pooling of mucus in the bronchiolar passages. Daily treatment of DPB with macrolide antibiotics such as erythromycin eases symptoms and increases survival time, but the disease currently has no known cure. The eventual result of DPB can be respiratory failure and heart problems.


Epidemiology

DPB has its highest prevalence among the Japanese, at 11 per 100,000 population. Korean, Chinese, and Thai individuals with the disease have been reported as well. A genetic predisposition among East Asians is suggested. The disease is more common in males, with the male to female ratio at 1.4–2:1 (or about 5 men to 3 women). The average onset of the disease is around age 40, and two-thirds of those affected are non-smokers, although smoking is not believed to be a cause. The presence of HLA-Bw54 increases the risk of diffuse panbronchiolitis 13.3-fold.

In Europe and the Americas, a relatively small number of DPB cases have been reported in Asian immigrants and residents, as well as in individuals of non-Asian ancestry. Misdiagnosis has occurred in the West owing to less recognition of the disease than in Asian countries. Relative to the large number of Asians living in the west, the small number of them thought to be affected by DPB suggests non-genetic factors may play some role in its cause. This rarity seen in Western Asians may also be partly associated with misdiagnosis.


History

In the early 1960s, a relatively new chronic lung disease was being observed and described by physicians in Japan. In 1969, the name "diffuse panbronchiolitis" was introduced to distinguish it from chronic bronchitis, emphysema, alveolitis, and other obstructive lung disease with inflammation. Between 1978 and 1980, results of a nationwide survey initiated by the Ministry of Health and Welfare of Japan revealed more than 1,000 probable cases of DPB, with 82 histologically confirmed. By the 1980s, it was internationally recognized as a distinct disease of the lungs.

Before the 1980s, the prognosis or expected outcome of DPB was poor, especially in cases with superinfection (the emergence of a new viral or bacterial infection, in addition to the currently occurring infection) by P. aeruginosa. DPB continued to have a very high mortality rate before generalized antibiotic treatment and oxygen therapy were beginning to be used routinely in the effort to manage symptoms. Around 1985, when long-term treatment with the antibiotic erythromycin became the standard for managing DPB, the prognosis significantly improved. In 1990, the association of DPB with HLA was initially asserted.



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Hallermann Streiff Syndrome


https://rarediseases.org/rare-diseases/hallermann-streiff-syndrome/




General Discussion

Summary

Hallermann-Streiff syndrome (HSS) is a rare disorder that is primarily characterized by distinctive malformations of the skull and facial (craniofacial) region; sparse hair (hypotrichosis); eye abnormalities; dental defects; degenerative skin changes (atrophy), particularly in the scalp and nasal regions; and proportionate short stature. Characteristic craniofacial features include a short, broad head (brachycephaly) with an unusually prominent forehead and/or sides of the skull (dyscephaly); a small, underdeveloped lower jaw (hypoplastic mandible); a narrow, highly arched roof of the mouth (palate); and a thin, pinched, tapering nose. Many affected individuals also have clouding of the lenses of the eyes at birth (congenital cataracts or corneal stromal opacities); unusually small eyes (microphthalmia); and/or other ocular abnormalities (glaucoma, retinal detachments). Dental defects may include natal or neonatal teeth, delayed tooth eruption, enamel hypoplasia, absent permanent teeth (hypodontia or partial adontia), abnormal tooth development resulting in short roots and early loss of teeth, and/or improper alignment of teeth. In almost all cases, HSS has appeared to occur randomly for unknown reasons (sporadically), and this syndrome is thought to be the result of a new change to genetic material (mutation).

Introduction

Hallermann-Streiff syndrome was first described in the medical literature in 1893. The disorder was named for two eye doctors who later independently reported cases of the syndrome, recognizing it as a distinct disease entity.
Signs & Symptoms

Associated symptoms and signs vary greatly in range and severity from case to case. The principal features of Hallermann-Streiff syndrome include abnormalities of the skull (cranium) and certain bones of the face (known as dyscephaly); distinctive facial features; ocular defects; dental anomalies; and/or proportionate short stature. In many cases, additional abnormalities are also present.

Many affected infants have an unusually shaped skull, with abnormal shortness of the head (brachycephaly) and prominence of the forehead and/or sides of the skull (frontal and/or parietal bossing). In some cases, the head may also be relatively small (microcephaly) and the cheekbones may be underdeveloped (malar hypoplasia). In addition, there is typically abnormal widening of the fibrous joints (sutures) between certain bones of the skull and delayed closure of the two “soft spots” (fontanelles) at the front and back of the cranium.

Affected individuals also often have a disproportionately small face; a high, narrow roof of the mouth (palate); and/or a small lower jaw (micrognathia) with receding chin (retrognathia). The nose is typically quite narrow and pointed; with a narrow nasal bridge, small nostrils and underdeveloped nasal cartilage that tends to become more convex (beaked) with age. The underdevelopment of the jaw and nose may result in upper airway obstruction and breathing difficulties in young children. In addition, many people with this syndrome have very sparse hair (hypotrichosis), particularly of the scalp, eyelashes, eyebrows, beard, pubic hair, and hair under the arms. Degenerative skin changes (atrophy) are also often present and largely limited to the scalp and nose. Due to such changes, the skin in these regions may appear unusually taut and thin, and regional blood vessels may seem unusually pronounced. Nasal lipofilling has been used to treat the atrophy of the nasal skin, resulting in improvement in nasal skin color and texture.

The craniofacial abnormalities associated with the disorder, such as small nostrils and glossoptosis, can cause obstruction of the upper airway, particularly during the newborn period and infancy. Glossoptosis refers to downward displacement or retraction of the tongue that may occur secondary to abnormal smallness of the lower jaw (micrognathia). A narrow upper airway may lead to feeding, swallowing, and/or breathing difficulties; severe early respiratory infections; episodes in which there is absence of spontaneous breathing (apnea); anesthetic complications; and potentially life-threatening complications in severe cases. Abnormal softening of cartilage of the windpipe (tracheomalacia) has also been reported in some cases, which may further complicate swallowing and breathing difficulties. In addition, there have also been reports in which respiratory insufficiency (e.g., due to a narrow upper airway and/or tracheomalacia) has resulted in enlargement and strain of the lower right chamber (ventricle) of the heart (cor pulmonale) and possibly the left ventricle as well, leading to heart failure. Heart failure is an inability of the heart to pump enough blood to meet the body’s requirements for oxygen and other nutrients.

Most individuals with HSS have ocular abnormalities. The most common ocular finding is clouding (opacity) of the lenses of both eyes at birth (congenital bilateral cataracts). According to reports in the medical literature, the cataracts, which consist of whitish, milky lens masses, may gradually spontaneously resolve (spontaneous cataract absorption) in some cases. Many individuals with this disorder also have abnormal smallness of both eyes (bilateral microphthalmia) of varying severity and/or unusually deep-set eyes (enophthalmos). As a result of these small deeply-seated eyes, patients may appear to have small, droopy eyelids (blepharoptosis). The edges of the eyelids may appear to turn inwards, particularly on the lower side (lower lid entropion) so that the eyelashes rub against the eye surface (cornea) leading to irritation, erosions and corneal opacities. Some eye experts suggest corneal stromal opacities, which are ill defined and bilateral with clear stroma between the opacities might be a hallmark feature of this condition. In some cases, additional ocular defects may also be present, such as abnormal deviation of one eye in relation to the other (strabismus); involuntary, rapid, rhythmic eye movements (nystagmus); unusual blueness of the “whites” of the eyes (blue sclera); abnormally elevated pressure of the fluid of the eyes (glaucoma); retinal detachments; down-slanting eyelids (palpebral fissures); or malformed orbital bones and/or other findings. Such ocular defects may result in varying degrees of visual impairment or, in some cases, blindness.

Hallermann-Streiff syndrome is frequently characterized by dental abnormalities. These may include the eruption of teeth before or shortly after birth (natal or neonatal teeth), which may be misdiagnosed as supernumerary teeth. There is also delayed eruption of permanent teeth, abnormal tooth development, with severely undeveloped roots leading to early loss of permanent teeth and partially developed crowns, improper contact between the teeth of the upper jaw and those of the lower jaw (malocclusion), and/or persistence of the primary (deciduous) teeth. Additional dental defects may include absence of permanent teeth (hypodontia or anodontia), and/or severe, early tooth decay with enamel hypoplasia.

In approximately one third of reported cases, infants with HSS are born prematurely and/or have a low birth weight. About two thirds of affected individuals have growth deficiency after birth and associated proportionate short stature.

In some cases, additional physical abnormalities have also been reported in association with the disorder. Some affected males may have decreased testicular function (hypogonadism), undescended testes (cryptorchidism), and/or abnormal placement of the urinary opening of the penis (hypospadias). Skeletal abnormalities have also been reported in some cases, such as widely flared shoulder blades (winged scapula), abnormal curvature of the spine (lordosis or scoliosis), abnormal depression of the breastbone (pectus excavatum), and/or webbing of fingers and/or toes (syndactyly). Radiological findings in infants can include a large, poorly ossified skull with decreased ossification in the sutural areas, multiple Wormian bones within sutures, and severe mid-facial hypoplasia with a prominent nasal bone, small teeth, thin and gracile long bones with poor demarcation of the cortex from the medullary portion, neonatal bowing of the radius and ulna and widening at the metaphyseal ends of the long bones. Some affected infants may also have vitiligo, a condition characterized by irregular patches of skin that lack pigmentation. In addition, in rare cases, various structural heart malformations (congenital heart defects) have been reported. Such congenital heart defects have included an abnormal opening in the partition (septum) that separates the lower or upper chambers of the heart (ventricular or atrial septal defects) or abnormal narrowing of the opening between the pulmonary artery and the right ventricle of the heart (pulmonary stenosis).

In most cases, children with this disorder have normal intelligence; however, intellectual disability has been reported in approximately 15 percent of cases. In rare instances, neurologic abnormalities have been noted, including hyperactivity; seizures, and/or choreoathetosis, a condition characterized by abnormal, involuntary, irregular jerky motions and slow, writhing movements. With more patients undergoing MRI studies, various structural abnormalities of the brain have been reported. One as such case showed the absence of the corpus callosum (the thick band of nerve fibers that connects the right and left halves of the brain).


Causes

In almost all reported cases, Hallermann-Streiff syndrome has occurred randomly for unknown reasons (sporadically), most likely due to a new spontaneous dominant genetic change (mutation). There have been reports of patients with this disorder reproducing successfully and bearing multiple normal children. From families with an affected child, there is little evidence for this being a recessively inherited disorder in which both parents are carriers (normal looking but carry the mutation). Therefore, the mode of inheritance of this disorder remains elusive making it difficult to determine the exact recurrent risk.

Hallermann-Streiff syndrome bears some similarity to some progeroid syndromes that belong to the laminopathies, such as Hutchinson-Gilford progeria syndrome (caused by de novo point mutations in the LMNA gene) and mandibuloacral dysplasia (recessive disorders resulting from mutations in LMNA and ZMPSTE24). ZMPSTE24 and ICMT encode proteins involved in posttranslational processing of lamin A. Sequencing of the genes LMNA, ZMPSTE24 and ICMT in 8 patients with Hallermann-Streiff syndrome revealed no evidence that this disorder is a type of laminopathy, but these other conditions remain part of the differential diagnosis, particularly when autosomal recessive inheritance is suspected.



Affected Populations

Hallermann-Streiff syndrome appears to affect males and females in relatively equal numbers. More than 150 cases have been reported in the medical literature.

Related Disorders

Symptoms of the following disorders can be similar to those of Hallermann-Streiff syndrome. Comparisons may be useful for a differential diagnosis:

Hutchinson-Gilford progeria syndrome is a very rare progressive disorder of childhood characterized by premature aging (progeria); growth delays occurring in the first year of life resulting in short stature and low weight; deterioration of the layer of fatty tissue beneath the skin (subcutaneous lipodystrophy); and characteristic craniofacial abnormalities including an abnormally small face, underdeveloped jaw (micrognathia), unusually prominent eyes, and/or a small, “beak-like” nose. In addition, during the first year or two of life, scalp hair, eyebrows, and eyelashes may become sparse, and veins of the scalp may become unusually prominent. Additional symptoms and physical findings may include joint stiffness, repeated non-healing fractures, a progressive aged appearance, delays in tooth eruption (dentition), and/or malformation and crowding of the teeth. Individuals with the disorder typically have normal intelligence. In most cases, affected individuals develop premature, widespread thickening and loss of elasticity of arterial walls (arteriosclerosis), potentially resulting in life-threatening complications. Hutchinson-Gilford progeria syndrome is due to a de novo heterozygous mutation in the lamin A gene (LMNA) on chromosome 1q22. (For more information on this disorder, choose “Hutchinson Gilford” as your search term in the Rare Disease Database) Other disorders with less severe, but overlapping features include mandibuloacral dysplasia, an autosomal recessive disorder, which is caused by different mutations in the LMNA gene or the ZMPSTE24 gene, and Werner syndrome, an autosomal recessive progeroid syndrome caused by autosomal recessive mutations in the RECQL2 gene.

Wiedemann-Rautenstrauch syndrome (also known as neonatal progeroid syndrome) is an extremely rare genetic disorder characterized by an aged appearance at birth (neonatal progeroid appearance); growth delays before and after birth (prenatal and postnatal growth deficiency); and deficient or absent fatty tissue under the skin (subcutaneous lipoatrophy), causing the skin to appear abnormally thin, fragile, and wrinkled. In addition abnormal deposits of fat may accumulate around the buttocks, flanks, genitals and anus (anogenital area). Affected infants and children have distinctive facial features with unusual prominence of the forehead (frontal bossing) and the sides of the skull (parietal bossing), causing the head to appear large (pseudohydrocephalus); unusually small, underdeveloped (hypoplastic) bones of the face and abnormally small facial features; a small “beak-shaped” nose that becomes more pronounced with advancing age; and/or sparse scalp hair, eyebrows, and/or eyelashes. Most infants and children with Wiedemann-Rautenstrauch syndrome have unusually thin arms and legs; abnormally large hands and feet; progressive neurological and neuromuscular abnormalities; varying degrees of intellectual disability; and severe delays in the acquisition of skills requiring the coordination of mental and muscular activities (psychomotor retardation). In addition, affected infants and children are prone to repeated respiratory infections that may result in life-threatening complications. Wiedemann-Rautenstrauch syndrome is inherited as an autosomal recessive genetic trait. Core manifestations of this syndrome include marked pre-natal and severe post-natal growth retardation, an unusual face (triangular shape, sparse hair, small mouth, pointed chin), dental anomalies (natal teeth; hypodontia), generalized lipodystrophy with localized fat masses, and-in some cases-progressive ataxia and tremor. It has been suggested that the syndrome might be caused by biallelic variants in POLR3A, identified by exome sequencing in a single patient only. There are major differences but there are also similarities in phenotype, which sustain the suggestion that the syndrome can be caused by disturbed POLR3A functioning.

Seckel syndrome is an extremely rare autosomal recessive disorder characterized by growth deficiency prior to birth (intrauterine growth retardation) resulting in low birth weight. Growth deficiency continues after birth, resulting in severe proportionate short stature. Other symptoms and physical features associated with Seckel syndrome include an abnormally small head (microcephaly); varying degrees of intellectual disability; and/or unusual characteristic facial features including “beak-like” protrusion of the nose. Other facial features may include abnormally large eyes, a narrow face, malformed ears, and/or an unusually small jaw (micrognathia). In addition, some affected infants exhibit incurving of the fifth fingers in a bent position (clinodactyly), congenital hip dysplasia, dislocated forearms (radial dislocation), and/or other physical abnormalities. Seckel syndrome inherited as an autosomal recessive genetic trait due to homozygous or compound heterozygous mutation in the ATR gene on chromosome 3q22.1-q24. Other syndromes resembling this disorder are caused by mutations in the RBBP8 gene on chromosome 18q11.31-q11.2; mutations in the CENPJ gene on chromosome 13q12; mutations in the CEP152 gene on chromosome 15q21; or mutations in CDK5RAP2 on chromosome 9q33.2.

Osteodysplastic bird-headed dwarfism, also known as Majewski osteodysplastic primordial dwarfism (MOPD) is an extremely rare inherited disorder characterized by low birth weight, prenatal-onset growth deficiency resulting in severe proportionate short stature with an unusually small head (microcephaly), and characteristic facial features including prominence of the nose, abnormally large eyes, an unusually small jaw (micrognathia) that is recessed (retrognathia), a narrow face, and/or low-set ears. In some cases, affected children may exhibit other abnormalities, such as mild intellectual disability, skeletal deformities, and/or patchy areas of hair loss (alopecia) on the scalp. There are three types of MOPD, designated type I, II, and III that are distinguished by differences in their symptoms. All are inherited as autosomal recessive genetic traits caused by mutations in different genes (MOPD I – RNU4ATAC; MOPD II – PCNT; MOPD III – possibly the same entity as MOPD I).

Among children who present with microcephaly and bilateral congenital cataracts with small eyes, one should also consider MICRO syndrome, a rare autosomal recessive disorder characterized by microcephaly, microphthalmia, microcornea, congenital cataracts, optic atrophy, corpus callosum hypoplasia, severe intellectual disability, spastic diplegia, and hypogonadism. This disorder is caused by mutation in the RAB3GAP2 gene on chromosome 1q41; the RAB3GAP1 gene on 2q21.3; the RAB18 gene on 10p12.1; or the TBC1D20 gene on 20p13.

Another possibility is early onset Cockayne syndrome, an autosomal recessive disorder resulting in severe failure to thrive, severe mental retardation, congenital cataracts, loss of adipose tissue, joint contractures, distinctive face with small, deep-set eyes and prominent nasal bridge, kyphosis, and cachectic dwarfism. This disorder is termed Cockayne syndrome type B (CSB) and caused by mutation in the gene encoding the group 6 excision-repair cross-complementing protein (ERCC6) on chromosome 10q11.23. Cockayne syndrome type A (CSA) is caused by mutation in the ERCC8 gene on chromosome 5q11. Among patients with Cockayne syndrome, approximately 80% have mutations in the ERCC6 gene.

Diagnosis

Hallermann-Streiff syndrome may be suspected shortly after birth or during the first year of life by the identification of characteristic physical findings and symptoms. The diagnosis may be confirmed by thorough clinical evaluation; a detailed patient history; and specialized tests (e.g., radiographic, ophthalmologic, and dental studies) that may help to detect and characterize the abnormalities associated with this disorder. Congenital cataracts with unusually small eyes (microphthalmia) are important findings for the initial diagnosis of Hallermann-Streiff syndrome, but other disorders must be considered as part of the differential diagnosis, and this is best accomplished through whole exome sequencing given the extensive differential diagnosis, which includes a number of autosomal recessive disorders.




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A familial study of Hallermann–Streiff–François syndrome


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476608/

Abstract

Hallermann–Streiff–François syndrome is a rare sporadic genetic pathology characterized by a phenotype consisting of growth retardation, ocular abnormalities, and a “bird-like head”. We hereby report a case of this syndrome found in three generations of the same family – father, daughter, and grand-daughter – who presented with a short stature and facial dysmorphic features, nystagmus, cataract, and bilateral microphthalmia. The discussion is based on the clinical and genetic aspects, and the challenges in management of this oculo-mandibulo-facial syndrome. The association of congenital cataract, facial dysmorphic features, and microphthalmia, should guide the diagnosis of dysmorphic syndromes such as Hallermann–Streiff–François syndrome.








Case 1: bird-like face with strabismus and nystagmus.












Case 2: nasal skin atrophy.



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Parasitic infections of the lung: a guide for the respiratory physician

Abstract

 

https://thorax.bmj.com/content/66/6/528

Parasitic infections of the lung occur worldwide among both immunocompetent and immunocompromised patients and may affect the respiratory system in a variety of ways. This review provides an update on the presenting symptoms, signs, investigation and management of diseases affecting the lung caused by protozoa, nematodes and trematodes. The clinical presentations and radiographic findings of several of these diseases may mimic tuberculosis and malignancy. It is important to consider parasitic infections in the differential diagnosis of such lung diseases. If identified early, most parasitic diseases that affect the lung are curable with medical or surgical treatments.

Introduction

With increasing travel and migration, rates of parasitic lung and pleural diseases are increasing in the immunocompetent population in developed countries as well as among immunocompromised patients. Respiratory physicians should consider parasitic diseases in the differential diagnosis of lung conditions such as tuberculosis and malignancy, with which parasitic lung diseases may be confused.

This review describes the presentation, investigation and management of common parasitic infections affecting the lung caused by protozoa, nematodes and trematodes. The diseases have been grouped according to their manner of presentation: (1) those presenting with focal lesions and (2) those which characteristically present with diffuse lung disease. Focal lung lesions have been divided into cystic lung lesions, coin lesions and consolidation/pleural effusion. Diffuse lung disease has been divided into transient pulmonary infiltrates and alveolar/interstitial lung changes. Diseases that may present in a variety of ways are fully described only the first time they are mentioned.

Conditions presenting with focal lung lesions

Cystic lung lesions

Hydatidosis

Distribution and life cycle

Hydatid disease is caused by larvae of Echinococcus tapeworm species, the definite hosts of which are members of the Canidae family (dogs and foxes). Most cases are caused by Echinococcus granulosus which has a worldwide distribution including South America, countries surrounding the Mediterranean, the Middle East, some sub-Saharan African countries, Russia and China. Although most cysts form in the liver, 20–30% form in the lung.

Dogs are the definitive host for E granulosus and harbour the adult worms in their gut. The eggs shed in dog faeces remain viable for many weeks and are able to contaminate food sources of intermediate hosts such as sheep, cattle and horses. When humans become accidental intermediate hosts after eating food contaminated with eggs, the ingested eggs hatch, releasing larvae which migrate from the gastrointestinal tract to the circulation. The eggs travel to the liver or lungs and slowly develop into hydatid cysts over a period of several months or years. Occasionally, lung cysts form after transdiaphragmatic spread of parasites following the rupture of liver cysts.




-------------------------------------------




Tracheal surgery using 4D-printing technology successful in China

 2016-04-19

https://www.chinadaily.com.cn/life/2016-04/19/content_24670067.htm



--------------------------------------------




Tracheal collapse

https://en.wikipedia.org/wiki/Tracheal_collapse

Tracheal collapse in dogs is a condition characterized by incomplete formation or weakening of the cartilaginous rings of the trachea resulting in flattening of the trachea. It can be congenital or acquired, and extrathoracic or intrathoracic (inside or outside the thoracic cavity). Tracheal collapse is a dynamic condition. Collapse of the cervical trachea or extrathoracic (in the neck) occurs during inspiration; collapse of the thoracic trachea or intrathoracic (in the chest) occurs during expiration. Tracheal collapse is most commonly found in small dog breeds, including the Chihuahua, Pomeranian, Toy Poodle, Shih Tzu, Lhasa Apso, Maltese, Pug, and Yorkshire Terrier.

Congenital tracheal collapse appears to be caused by a deficiency of normal components of tracheal ring cartilage like glycosaminoglycans, glycoproteins, calcium, and chondroitin. Acquired tracheal collapse can be caused by Cushing's syndrome, heart disease, and chronic respiratory disease and infection.

Symptoms include a cough (often called a "goose honk cough" due to its sound), especially when the dog is excited. This cough is usually paroxysmal in nature. Other symptoms include exercise intolerance, respiratory distress, and gagging while eating or drinking. Tracheal collapse is easily seen on a radiograph as a narrowing of the tracheal lumen. Treatment for mild to moderate cases include corticosteroids, bronchodilators, and antitussives. Medical treatment is successful in about 70 percent of tracheal collapse cases. Severe cases can be treated with surgical implantation of a tracheal stent (inside or outside of the trachea) or prosthetic rings. Extraluminal (outside the trachea) stenting is generally used only for tracheal collapse in the neck region. Intraluminal stenting has shown more promise for success with intrathoracic cases, especially using nitinol, a type of shape memory alloy composed of nickel and titanium. Potential problems include stent migration and fracture.

Tracheal collapse has also been described in horses, both as a congenital condition and as a result of trauma. It is most commonly seen in the cervical trachea.



--------------------------------------------



Cushing's syndrome

https://en.wikipedia.org/wiki/Cushing%27s_syndrome


Cushing's syndrome is the collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face, a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals poorly. Women may have more hair and irregular menstruation. Occasionally there may be changes in mood, headaches, and a chronic feeling of tiredness.

Cushing's syndrome is caused by either excessive cortisol-like medication such as prednisone or a tumor that either produces or results in the production of excessive cortisol by the adrenal glands. Cases due to a pituitary adenoma are known as Cushing's disease, which is the second most common cause of Cushing's syndrome after medication. A number of other tumors may also cause Cushing's.  Some of these are associated with inherited disorders such as multiple endocrine neoplasia type 1 and Carney complex. Diagnosis requires a number of steps. The first step is to check the medications a person takes. The second step is to measure levels of cortisol in the urine, saliva or in the blood after taking dexamethasone. If this test is abnormal, the cortisol may be measured late at night. If the cortisol remains high, a blood test for ACTH may be done.

Most cases can be treated and cured. If due to medications, these can often be slowly decreased if still required or slowly stopped. If caused by a tumor, it may be treated by a combination of surgery, chemotherapy, and/or radiation. If the pituitary was affected, other medications may be required to replace its lost function. With treatment, life expectancy is usually normal. Some, in whom surgery is unable to remove the entire tumor, have an increased risk of death.

About two to three people per million are affected each year. It most commonly affects people who are 20 to 50 years of age. Women are affected three times more often than men. A mild degree of overproduction of cortisol without obvious symptoms, however, is more common. Cushing's syndrome was first described by American neurosurgeon Harvey Cushing in 1932. Cushing's syndrome may also occur in other animals including cats, dogs, and horses.



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Pattern of Lipid Abnormalities Among South Asian Indians With Cushing's Syndrome and the Short Term Impact of Surgical Correction of Hypercortisolism.

2019

https://www.ncbi.nlm.nih.gov/pubmed/31071735


Abstract

Atherosclerotic cardiovascular events are one of the common causes of mortality in patients with Cushing's syndrome (CS). Atherogenic dyslipidemia is more common among South Asian Indians as compared to other ethnicities and is likely to worsen among patients with CS. This retrospective study was done over 5 years at a single institute to evaluate the pattern of lipid abnormalities in subjects with CS and the changes in lipid parameters after surgical control of hypercortisolemia. The study was done in two parts. In the first part, records of patients with CS diagnosed over 3 years were retrospectively reviewed. Hormonal and metabolic parameters including fasting plasma glucose (FPG), post prandial plasma glucose (PPPG), HbA1c, serum lipids, serum cortisol and plasma ACTH were recorded. In the second part, lipid parameters were rechecked among patients who underwent surgery and a median follow up of 4±2 months after remission. Out of the 126 patients diagnosed with endogenous CS over 3 years, 100 patients were eligible for inclusion in the study. At baseline, sixty five (65%) patients had dyslipidemia as defined by the NCEP-ATPIII criteria. 47 out of 63 (74.6%) subjects achieved remission after surgical management of CS. 32 (68.1%) of these patients had dyslipidemia prior to surgery. After excluding 1 death, 26 of 46 (56.5%) subjects had dyslipidemia after the follow up period. Lipid abnormalities are common among South Asian Indian subjects with endogenous CS and the pattern persists in most of them, 3 months after surgical correction of hypercortisolism.



---------------------------------------------



Why Are Thyroid Cancer Rates So High in Southeast Asian Women Living in the United States? The Bay Area Thyroid Cancer Study

February 2003

https://cebp.aacrjournals.org/content/12/2/144



---------------------------------------------



Large toxic multinodular goiter found in Asian woman with type 2 diabetes

June 2014

https://www.healio.com/endocrinology/neuroendocrinology/news/print/endocrine-today/%7B4c86da15-bbd9-48dd-8bea-59ae27c862bb%7D/large-toxic-multinodular-goiter-found-in-asian-woman-with-type-2-diabetes



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Technique and outcome of autotransplanting thyroid tissue after total thyroidectomy for simple multinodular goiters.

2017

https://www.ncbi.nlm.nih.gov/pubmed/26337375



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Untreated Goiters Larger at Surgery in Men, Minorities, and the Old

2016

https://www.medscape.com/viewarticle/860299

Significant disparities exist in the presentation and outcomes of patients with goiters in the United States, with minority ethnic groups, men, and older patients more likely to present with untreated goiters that have become so large they extend into the chest, meaning they are more difficult to remove, a nationally representative analysis shows.



----------------------------------------------




Evaluation of Serum Hepatocellular Enzymes in Nigerian with Goitre

https://www.nepjol.info/index.php/AJMS/article/view/3870




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Goiter Prevalence in Children in North India Region

https://www.alliedacademies.org/articles/goiter-prevalence-in-children-in-north-india-region.pdf

There is a significant association between the age of school children  and  prevalence  of  goiter.  In  addition  the  preva-lence among girls was more than boys. The observed result is almost consistent with earlier observations Conclusion:In the summary that the present data showed that the prev-alence of the goiter in the age group of the 5-13 in the rural area  of  the  north  India.  This  indicated  that  the  presence  of  the  Iodine  in  the  salt  &  the  food  is  less.  So  the  action  needs to be taken to control such situations. Also it shows that there is need to implement the ban on the non iodized salt in the area. Also the efforts must be taken to improve awareness  regarding  the  use  of  Iodized  salt  to  avoid  the  Goiter.



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Japan’s iodine status – too high or just right?

https://www.ign.org/newsletter/idd_aug15_japan.pdf

‘Endemic coast goiter’ and iodine nutritionThe misconception that most Japanese con-sume too much iodine may have its roots in several early studies in the coastal area of Hokkaido. In 1933, Jesse F McClendon of the University of Minnesota reported that Japan was the only non-goitrous country in the world, with one case of goiter per million people. The northern island of Hokkaido was an apparent exception, where cases of endemic goiter could be traced back to 1899. But when later surveys, con-ducted between 1948 and 1952, reported goiter throughout Japan (with goiter rates in children ranging from 0.9% to 20.6% across 11 of 46 prefectures), they went lar-gely unnoticed by the international scientific community.


-----------------------------------------------



Total Thyroidectomy: The Procedure of Choice for Toxic Goitre

https://core.ac.uk/download/pdf/82353036.pdf


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Role of Goiter and of Menstrual and Reproductive Factors in Thyroid Cancer:A Population-based Case-Control Study in New Caledonia (South Pacific), a Very High Incidence Area

https://www.ncbi.nlm.nih.gov/pubmed/15901626


-----------------------------------------------


Multinodular goiter: A study of malignancy risk in nondominant nodules

https://journals.sagepub.com/doi/pdf/10.1177/014556131709600821


---------------------------------------------


Thyroid Disease in Dogs

2018

https://www.akc.org/expert-advice/health/thyroid-disease-in-dogs/

Some breeds do appear to be at greater risk of developing hypothyroidism than others. Medium-to-large-size breeds are more likely to develop the disease than toy and miniature breeds, and the Cocker Spaniel, Miniature Schnauzer, Dachshund, Doberman Pinscher, Golden Retriever, Airedale Terrier, and Irish Setter appear to be predisposed to developing the condition.


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Hashimoto's Thyroiditis

Also called Hashimoto's disease, Hashimoto's thyroiditis is an autoimmune disease, a disorder in which the immune system turns against the body's own tissues. In people with Hashimoto's, the immune system attacks the thyroid. This can lead to hypothyroidism, a condition in which the thyroid does not make enough hormones for the body's needs.

https://www.webmd.com/women/hashimotos-thyroiditis-symptoms-causes-treatments#1



------------------------------------------------



Hashimoto's Thyroiditis: From Genes to the Disease

2011

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271310/



-------------------------------------------------



IgG4-related fibrous variant of Hashimoto thyroiditis in a non-Asian woman

2017

https://www.endocrine-abstracts.org/ea/0049/ea0049gp213



-------------------------------------------------



Immunogenetics of Hashimoto's thyroiditis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555850/



-------------------------------------------------



Variation in Rates of Autoimmune Thyroid Disease by Race/Ethnicity in US Military Personnel

2014


https://jamanetwork.com/journals/jama/fullarticle/1860451



Results

The DMSS recorded 20 270 688 person-years of eligible active-duty service during the study period (85.8% male). There were 1378 cases of Graves disease in women and 1388 cases in men and 758 cases of Hashimoto thyroiditis in women and 548 cases in men (Table).

Compared with whites, the IRR for Graves disease was significantly elevated in black women (IRR, 1.92; 95% CI, 1.56-2.37) and men (IRR, 2.53; 95% CI, 2.01-3.18) and Asian/Pacific Islander women (IRR, 1.78; 95% CI, 1.20-2.66) and men (IRR, 3.36; 95% CI, 2.57-4.40) (Figure). In contrast, Hashimoto thyroiditis incidence was highest in whites and lowest in black women (IRR, 0.33; 95% CI, 0.21-0.51) and men (IRR, 0.22; 95% CI, 0.11-0.47) and Asian/Pacific Islander women (IRR, 0.31; 95% CI, 0.17-0.56) and men (IRR, 0.23; 95% CI, 0.07-0.72) (Figure).

Discussion

To our knowledge, this is the first report to identify that Graves disease is more common in blacks and Asian/Pacific Islanders compared with whites. In contrast, the relationship between Hashimoto thyroiditis and race is well known,1,2 and is confirmed by our results.

The differences in incidence by race/ethnicity may be due to different environmental exposures, genetics, or a combination of both. Our results are not easily attributable to the strongest known environmental risk factor, cigarette smoking.

Smoking is associated with an increased risk for Graves disease and a decreased risk of Hashimoto thyroiditis.4,5 Whites have the highest smoking rates in the US military. However, whites had higher rates of Hashimoto thyroiditis and lower rates of Graves disease.

Our data set presumes accurate coding; it is possible that some cases of Hashimoto thyroiditis causing hypothyroidism were coded as unspecified-acquired hypothyroidism and not Hashimoto thyroiditis. The military population may also tend to have lower Hashimoto thyroiditis estimates because it is younger than the general population and has higher smoking prevalence.

Another potential limitation is the misclassification of prevalent cases as incident cases, although this is unlikely to be important because diagnosis during the teenage years is rare. We also cannot rule out military-specific exposures affecting the pattern of autoimmune thyroid disease, which could limit the generalizability of our findings.



-----------------------------------------------


Treatment for Graves’ disease focuses on controlling overactive thyroid

2019

https://www.sun-sentinel.com/florida-jewish-journal/fl-jj-treatment-graves-disease-controlling-overactive-thyroid-20190213-story.html


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Genetics of Thyroid Function and Disease

2011

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219766/



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Unit 731

https://en.wikipedia.org/wiki/Unit_731


Unit 731, also referred to as Detachment 731, the 731 Regiment, Manshu Detachment 731, The Kamo Detachment:198 Ishii Unit, Ishii Detachment or the Ishii Company, was a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that undertook lethal human experimentation during the Second Sino-Japanese War (1937–1945) of World War II. It was responsible for some of the most notorious war crimes carried out by Imperial Japan. Unit 731 was based at the Pingfang district of Harbin, the largest city in the Japanese puppet state of Manchukuo (now Northeast China), and had active branch offices throughout China and Southeast Asia.

Its parent program was officially known as the Epidemic Prevention and Water Purification Department of the Kwantung Army. Originally set up under the Kempeitai military police of the Empire of Japan, Unit 731 was taken over and commanded until the end of the war by General Shirƍ Ishii, a combat medic officer in the Kwantung Army. The facility itself was built in 1935 as a replacement for the Zhongma Fortress, and to expand the capabilities for Ishii and his team. The program received generous support from the Japanese government up to the end of the war in 1945.

Unit 731 and the other Units of the "Epidemic Prevention and Water Purification Department" were biological weapon production, testing, deployment and storage facilities. They routinely tested on human beings (who were referred to internally as "logs"). Additionally, the biological weapons were tested in the field on cities and towns in China. Estimates of those killed by Unit 731 and its related programs range up to half a million people.



-----------------------------------------------



Extrinsic Factors Influencing Fetal Deformations and Intrauterine Growth Restriction

https://www.hindawi.com/journals/jp/2012/750485/


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Dog and Cat Nose Bleeds: Epistaxis

http://www.pethealthnetwork.com/dog-health/dog-diseases-conditions-a-z/dog-and-cat-nose-bleeds-epistaxis

There are several causes of epistaxis

    Trauma
    Clotting abnormalities (e.g., von Willebrand’s disease, hemophilia, or disseminated intravascular coagulation)
    Platelet problems
    Cancer (e.g., nasal adenocarcinoma)
    Benign tumors (e.g., polyps)
    Foreign bodies (e.g., sticks, plant material, etc.)
    Infections (e.g., parasites, fungal, tick-born, or bacterial causes)
    Dental disease (e.g., tooth root abscesses)
    Vasculitis



-----------------------------------------------



Is admission for epistaxis more common in Caucasian than in Asian people? A preliminary study.

2006

OBJECTIVES:

Epistaxis is a common ENT complaint. Although casual observation suggested that it is more common in Caucasian, compared with Asian people, a literature search failed to find any studies investigating ethnicity and epistaxis. The aim of this study was to identify any differences in emergency admission rates for epistaxis between Asian and Caucasian people.

https://www.ncbi.nlm.nih.gov/pubmed/17014447



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Impact of sex, age, race, ethnicity, and aspirin use on bleeding symptoms in healthy adults


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017649/



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Racial and Ethnic Differences in Self-Reported Periodontal Disease in the Multi-Ethnic Study of Atherosclerosis (MESA)



https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970861/


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Dental Health Is Worse in Communities of Color

May 12, 2016

Four key disparities show how these populations are vulnerable

Dental care is one of the nation’s greatest unmet health needs. In particular, communities of color have much higher rates of tooth decay and tooth loss and fewer dental visits and preventive treatments than white populations. Economic hardship also negatively affects access to dental care for many people of color. Although more research is needed to understand and address the factors that contribute to dental health disparities, significant evidence shows that communities of color face real problems and indicates that the nation’s dental care delivery system is failing to adequately support the oral health of all Americans.
Children of color are less likely than white children to see a dentist and receive preventive care

https://www.pewtrusts.org/en/research-and-analysis/articles/2016/05/12/dental-health-is-worse-in-communities-of-color



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Oral health-related cultural beliefs for four racial/ethnic groups: Assessment of the literature

https://bmcoralhealth.biomedcentral.com/articles/10.1186/1472-6831-8-26



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The Impact of Socioeconomic Status and Race-Ethnicity on Dental Health

2007


https://www.jstor.org/stable/10.1525/sop.2007.50.1.7?seq=1


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Racial Differences in Periodontal Disease and 10-Year Self-Reported Tooth Loss among Late Middle-Aged and Older Adults: The Dental ARIC Study

2017

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718983/



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Racial And Ethnic Disparities In Dental Care For Publicly Insured Children

Abstract

Poor oral health has important implications for the healthy development of children. Children in Medicaid, especially Latinos and African Americans, experience high rates of tooth decay, yet they visit dentists less often than privately insured children. Even Latino and African American children with private insurance are less likely than white children to visit dentists and have longer intervals between dental visits. Furthermore, Latino and African American children in Medicaid are more likely than white children in Medicaid to have longer intervals between visits. These findings raise concerns about Medicaid’s ability to address disparities in dental care access and, more broadly, in health care.

https://www.healthaffairs.org/doi/full/10.1377/hlthaff.2009.0089


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{Could the reason why Mexicans have higher tooth decay is that they live in third world conditions, and they have a brachycephalic skull. It is important that we research human skulls and find the reason why Mexicans have a lower IQ and more teeth problems}.





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CDC: Half of American Adults Have Periodontal Disease

Data from the Centers for Disease Control and Prevention show high prevalence of periodontal disease in the U.S. population; American Academy of Periodontology encourages yearly comprehensive periodontal evaluations to assess for disease.

CHICAGO—September 4, 2012—One out of every two American adults aged 30 and over has periodontal disease, according to recent findings from the Centers for Disease Control and Prevention (CDC). A study titled Prevalence of Periodontitis in Adults in the United States: 2009 and 2010 estimates that 47.2 percent, or 64.7 million American adults, have mild, moderate or severe periodontitis, the more advanced form of periodontal disease. In adults 65 and older, prevalence rates increase to 70.1 percent. This study is published in the Journal of Dental Research, the official publication of the International and American Associations for Dental Research.

The findings also indicate disparities among certain segments of the U.S. population. Periodontal disease is higher in men than women (56.4 percent vs. 38.4 percent) and is highest in Mexican-Americans (66.7 percent) compared to other races. Other segments with high prevalence rates include current smokers (64.2 percent); those living below the federal poverty level (65.4 percent); and those with less than a high school education (66.9 percent).

https://www.perio.org/consumer/cdc-study.htm



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Britons have poor dental health… or so goes the stereotype. Is that old adage as false as a set of dentures? Claudia Hammond investigates.

2015

British children have fewer decayed, missing or filled teeth than those in France, Spain – or the US

https://www.bbc.com/future/article/20150602-do-the-british-have-bad-teeth


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Color/race inequalities in oral health among Brazilian adolescents

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2009000300003



---------------------------------------------


Racial and ethnic variations in preventive dental care utilization among middle-aged and older Americans, 1999–2008

Dec 2013

https://www.frontiersin.org/articles/10.3389/fpubh.2013.00065/full



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Gum disease and heart disease: The common thread

March, 2018

https://www.health.harvard.edu/heart-health/gum-disease-and-heart-disease-the-common-thread

 


--------------------------------------------


Heart Disease in African-American Women

https://www.goredforwomen.org/en/about-heart-disease-in-women/facts/heart-disease-in-african-american-women

Heart disease and stroke is the No. 1 killer in women, and stroke disproportionately affects African-Americans. Importantly, African-American women are less likely than Caucasian women to be aware that heart disease is the leading cause of death.

Diabetes, smoking, high blood pressure, high blood cholesterol, physical inactivity, obesity and a family history of heart disease are all greatly prevalent among African-Americans and are major risk factors for heart disease and stroke. What’s more, African-American women have almost two times the risk of stroke than Caucasians, and more likely to die at an earlier age when compared to women of other ethnicities.


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Human ancestors had the same dental problems as us – even without fizzy drinks and sweets

https://theconversation.com/human-ancestors-had-the-same-dental-problems-as-us-even-without-fizzy-drinks-and-sweets-92546



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Novel contributions in canine craniometry: Anatomic and radiographic measurements in newborn puppies

2018

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940217/


---------------------------------


The Genetics of Canine Skull Shape Variation

https://www.genetics.org/content/193/2/317

---------------------------------


Understanding periodontal disease in dogs

https://animalwellnessmagazine.com/dog-prone-to-periodontal-disease/

Periodontal disease is common in all dogs, but factors such as breed and mouth conformation make some pooches more susceptible.

Periodontal disease is one of the top conditions veterinarians see in dogs. It affects not only the teeth and gums (gingiva) but the supportive structures that keep the teeth in place (such as the periodontal ligament or alveolar bone). Although all dogs are at risk for dental issues, some are more prone than others, depending on their breed, genes, the shape of their mouths, and even how much (or not) they chew their food.



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Great expectations, inconvenient truths, and the paradoxes of the dog-owner relationship for owners of brachycephalic dogs

2019

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641206/



----------------------------



Health Concerns of Brachycephalic Pets


https://www.mallardcreekvet.com/dr-waldens-blog/health-concerns-of-brachycephalic-pets


Impaired breathing

Many brachycephalic animals cannot breathe normally. Although the bones of the face are shortened, the soft tissues are not, leaving excess tissue that can block the airway. Signs of impaired breathing include snoring, snorting, and exercise intolerance. Brachycephalic animals are at risk for heat stroke, respiratory distress, and collapse. Long-term labored breathing can also cause digestive tract problems like gagging and vomiting. Obesity makes all of these problems worse.

Brachycephalic obstructive airway syndrome includes 3 main anatomic abnormalities: narrow nostrils, elongated soft palate (excess tissue at the roof of the mouth), and everted laryngeal saccules (tissue that blocks airflow through the trachea, or windpipe). Some animals require surgery to correct these problems. Brachycephalic animals may also have an abnormally narrow trachea, which gives the effect of constantly breathing through a small straw.

Eye disease

Brachycephalic animals have shallow eye sockets and large eyelid openings, so their eyes are not as well protected as those of other animals. Many also have impaired tear production (dry eye), reducing their defense against eye irritants. Skin folds at the top of the nose may cause hair to rub against the eyes. These problems can cause eye ulcers and eventual blindness.

Reproductive problems

Some brachycephalic breeds have trouble giving birth naturally because the puppies’ heads are too large to fit through the mother’s pelvis. One study found that over 80% of English bulldog, French bulldog, and Boston terrier litters born in the United Kingdom were delivered by cesarean section.

Skin and dental disease

Folds of loose skin give bacteria and yeast a handy place to grow, so brachycephalic animals are prone to skin fold infections. Because of their shortened upper jaw, they often have crowded or maloccluded teeth.



----------------------------



The truth behind brachycephalic breeds - appearance over welfare?

8-1-2018

https://www.spca.nz/news-and-events/news-article/the-truth-behind-brachycephalic-breeds-appearance-over-welfare



----------------------------



Should pugs and bulldogs be banned? It might be the only way to stop the suffering

10-24-2017

https://www.telegraph.co.uk/pets/news-features/pug-bulldog-ban-could-way-stop-suffering/


----------------------------



Brachycephalic airway obstructive syndrome

https://en.wikipedia.org/wiki/Brachycephalic_airway_obstructive_syndrome



----------------------------



Addressing Brachycephalic Ocular Syndrome in the Dog

https://todaysveterinarypractice.com/practical-techniques-from-the-navc-institute-addressing-brachycephalic-ocular-syndrome-in-the-dog-2/



---------------------------




We Are Breeding a World Full of Creatures That Cannot Survive

10-28-2017

https://futurism.com/breeding-world-creatures-cannot-survive



----------------------------



Selective Breeding Problems

9-16-2010


https://www.pbs.org/wnet/nature/dogs-that-changed-the-world-selective-breeding-problems/1281/


Skin problems

A skin allergy, atopic dermatitis, inflicts itchy, inflamed skin on as many as 15 percent of all dogs, but certain breeds are particularly susceptible. Dog breeds prone to atopic dermatitis include Dalmatians, Vizslas, and several terriers, such as the Boston Terrier, Bull Terrier, and the West Highland White Terrier. The numerous skin folds of a Chinese Shar-Pei, so valued by some breeders, can become breeding grounds for staphylococcus and other bacteria, which cause frequent skin infections. Also, excess wrinkles of skin on the face can rub on the eye, causing lesions and, potentially, blindness.

Immune system disease

In autoimmune disorders, an individual’s immune system, which normally works to fight off foreign invaders, launches a misguided attack against its own tissues and cells. A number of inherited diseases compromising the immune system have been noted in dogs, including primary severe combined immunodeficiency (a dog version of the “bubble boy” disease) among Basset hounds, Cardigan Welsh Corgis, and Dachshunds. Addison’s disease, an autoimmune disease that affects the hormone-producing adrenal glands, occurs more frequently among several particular breeds, including the Bearded Collie, Portuguese Water Dog, and Standard Poodles. Diabetes mellitus, an autoimmune disorder affecting the body’s response to sugars, shows up more frequently among Samoyeds and Australian Terrier dogs.

Blood disorders

Bassett Hounds are prone to an inherited abnormality the effects the ability of the platelets in the blood to clump together after an injury. The blood doesn’t clot properly, leading to hemorrhage and bruising. Clotting problems also plague dogs with von Willebrand’s disease, a genetic condition frequent in Doberman Pinschers.

Neurological, behavioral, and sensory

Neurological and behavioral problems afflict many pure breeds. Bull Terriers, for example, often compulsively chase their tails. Pugs are be predisposed to Pug Dog encephalitis, a fatal brain disease. Scottish Terriers are affected by Scottie Cramp, a disorder that causes the dogs to lose muscle control when they get excited. German Shepherds may inherit degenerative myelopathy, a crippling spinal cord disease that causes weakness and eventually paralysis.

Hearing and vision

Hereditary hearing loss is common in Dalmatians, Australian Cattle Dogs, and English Setters. Alaskan Malamutes, Siberian Huskies, Samoyeds, Bichon Frise, and more than 60 other purebred dogs suffer from inherited forms of cataracts, while progressive retinal atrophy, a common cause of blindness in purebreds, is particularly a problem in Old English Sheepdogs and Papillons.

Heart disease

Sudden death from cardiac disease is recurrent in several dog breeds, including Doberman Pinschers, Great Danes, Irish Wolfhounds, and German Shepherds. Boxers can be genetically predisposed to an irregular heartbeat. High blood pressure afflicts many small breeds including Poodles, Cocker Spaniels, Staffordshire terriers, among others.

Other organs and systems

Low thyroid function crops up most frequently in Alaskan Malamutes, English Setters, Golden Retrievers, Keeshonds, Samoyeds, and Siberian Huskies. Gastric torsion, or bloat, a potentially life-threatening inability to expel gas from the digestive system, is common among deep-chested breeds such as the Great Dane, Doberman, and German Shepherd. An inherited form of kidney disease affects English Cocker Spaniels, while Dalmatians are prone to kidney stones and Basenjis suffer from Fanconi Syndrome, a potentially fatal inherited disease in which the kidneys fail to reabsorb nutrients. Liver damage and cirrhosis are common in Bedlington Terriers because of an inherited condition called copper toxicosis, in which high levels of copper accumulate in the liver.

Cancer

Cancers are strongly influenced by genetics, and so it is not surprising to find various types of cancer among different dog breeds. For example, bone cancer, or osteosarcoma, is considerably more frequent among large and giant breeds of dogs, such as the Irish Wolfhound, Great Dane, Rottweiler, Labrador and Golden Retriever, Greyhound, and Saint Bernard, because their bones are stressed by carrying so much weight. High rates of malignant blood vessel tumors are seen among Golden Retrievers, which are also prone to leukemia and brain tumors. German Shepherd Dogs and Chow Chows are predisposed to gastric cancer, while Scottish Terriers are 18 times more likely to develop bladder cancer than are other breeds.


In the same way that inbreeding among human populations can increase the frequency of normally rare genes that cause diseases, the selective breeding that created the hundreds of modern dog breeds has put purebred dogs at risk for a large number of health problems, affecting both body and behavior.

Some conditions are directly related to the features breeders have sought to perpetuate among their dogs. As they deliberately manipulated the appearance of dogs to create or accentuate physical characteristics that were considered aesthetically pleasing, like the flat face of a bulldog or low-slung eyelids of a Bloodhound, breeders also created physical disabilities. The excessively wrinkled skin of the Chinese Shar-Pei causes frequent skin infection; Bulldogs and other flat-faced (or brachycephalic) breeds such as the Pekingese have breathing problems because of their set-back noses and shortened air passages; Bloodhounds suffer chronic eye irritation and infection.

The unnaturally large and small sizes of other breeds encourage different problems. For example, toy and miniature breeds often suffer from dislocating kneecaps and heart problems are more common among small dogs. Giant dogs such as Mastiffs, Saint Bernards, and Great Danes are nearly too big for their own good. Researchers have found a striking correlation between a dog’s large size and a frequency of orthopedic problems like hip dysplasia. Large dogs are often prone to heat prostration because they can’t cool down their bodies (tiny dogs, by contrast, have a hard time staying warm), and because of the massive weight they must support, these breeds are prone to malignant bone tumors in their legs. Meanwhile, the huge head and narrow hips of the Bulldog can necessitate that their pups must be born by Caesarean section.

Other health problems among purebreds are the product of both inbreeding and bad genetic luck. The genes responsible for many genetic diseases are “recessive,” which means that two copies of a damaged gene, one from the mother and one from the father, must be present in an individual for the disease to occur. Individuals that carry only one copy of the disease gene don’t have the condition, and are carriers of the disease. Normally, because disease genes are relatively rare, it is unlikely that both the mother and the father will be carriers, and even less likely that they’ll both give the disease gene to their offspring. But that’s not the case for purebred dog breeds, where genetically similar individuals are intentionally mated, increasing the concentration of disease genes. It’s like stacking a deck of cards with ten extra aces and ten extra face cards; the loaded deck increases your chance of hitting blackjack in a game of 21-but what you “win” might be allergies or a predisposition to cancer.


Bloodhounds suffer chronic eye irritation and infection


---------------------------




THE COST OF CUTENESS

Health and Welfare Issues Associated with
Brachycephalic Dog Breeds

https://www.hsvma.org/brachycephalic



---------------------------



Frenchie Breathing Problems Run Deeper Than Smushed Faces

May 16, 2019

French bulldogs are one of several breeds with a genetic mutation that can increase their risk of a disease called obstructive airway syndrome.

https://www.discovermagazine.com/planet-earth/frenchie-breathing-problems-run-deeper-than-smushed-faces


----------------------------


Pugs are anatomical disasters. Vets must speak out – even if it’s bad for business

2016

Owners must be told some breeds are born to a lifetime of suffering, even if it means upsetting clients and putting livelihoods on the line

https://www.theguardian.com/commentisfree/2016/sep/22/pugs-anatomical-disasters-vets-must-speak-out-even-bad-business



----------------------------



Pugs and bulldogs living miserable lives because of reckless breeding, vets say

13 Mar 2017

https://www.abc.net.au/news/2017-03-13/pugs-bulldogs-living-short-miserable-lives-veterinarians-say/8348686



-----------------------------



'This is a calamity': the surgeons keeping pugs and bulldogs alive

2019

https://www.theguardian.com/lifeandstyle/2019/feb/27/this-is-a-calamity-the-surgeons-keeping-pugs-and-bulldogs-alive



-----------------------------



 Bulldogs Are Genetic Monstrosities, DNA Study Finds

Jul 30 2016

Bulldogs are abominations of nature, and it’s definitely our fault.

https://www.vice.com/en_us/article/yp35mx/bulldogs-are-genetic-monstrosities-dna-study-finds



-----------------------------



Brachycephalic Airway Obstruction Syndrome in Flat-Faced Dogs

2001

https://veterinarypartner.vin.com/default.aspx?pid=19239&id=4951534



----------------------------



Glottic and skull indices in canine brachycephalic airway obstructive syndrome

2014

https://bmcvetres.biomedcentral.com/articles/10.1186/1746-6148-10-12


----------------------------



Effect of brachycephalic, mesaticephalic, and dolichocephalic head conformations on olfactory bulb angle and orientation in dogs as determined by use of in vivo magnetic resonance imaging

2012

https://www.researchgate.net/publication/228080398_Effect_of_brachycephalic_mesaticephalic_and_dolichocephalic_head_conformations_on_olfactory_bulb_angle_and_orientation_in_dogs_as_determined_by_use_of_in_vivo_magnetic_resonance_imaging



----------------------------



An ADAMTS3 missense variant is associated with Norwich Terrier upper airway syndrome

https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008102



----------------------------



Anaesthesia of brachycephalic dogs

2018

https://onlinelibrary.wiley.com/doi/full/10.1111/jsap.12948



----------------------------



Brachycephaly-related diseases

https://www.researchgate.net/publication/321107065_Brachycephaly-related_diseases



----------------------------




Feline asthma

Feline asthma is a common allergic respiratory disease in cats, affecting at least one percent of all adult cats worldwide. It is a chronic progressive disease for which there is no cure. Common symptoms include wheezing, coughing, labored breathing and potentially life-threatening bronchoconstriction. There is conjecture that the disease is becoming more common due to increased exposure to industrial pollutants.

At risk

Studies show that cats between the ages of two and eight years have the greatest risk of developing a respiratory disease. Siamese and Himalayan breeds and breed mixes seem to be most prone to asthma. Some studies also indicate that more female cats seem to be affected by asthma than male cats.


https://en.wikipedia.org/wiki/Feline_asthma



------------------------------



 THE ETHICS OF BREEDING FOR DEFORMITY: EXTREME BRACHYCEPHALY








 




 








http://messybeast.com/brachycephaly.htm



-----------------------------



Urgent call by vet profession to stop the suffering of brachycephalic dogs and cats

May 9th 2016

https://vethelpdirect.com/vetblog/2016/05/09/vets-to-end-suffering-of-brachycephalic-dogs/



------------------------------



 Skull variation in Dinaric-Balkan and Carpathian gray wolf populations revealed by geometric morphometric approaches

4-16-2010

https://academic.oup.com/jmammal/article/91/2/376/900808



------------------------------



Long Face Dog – And Fascinating Facts About Dog Head Shape

2017

https://thehappypuppysite.com/long-face-dog/




-----------------------------
-----------------------------



(The following chapter will explain in detail about the current steady decline in the biological human race.

We start in the dysgenic traits found in many species of animals that have regressed over the course of many years. New recent studies have shown that many of these brachycephalic traits found in certain species of animals have been classified as a form of biological decline in a biological species.

This new breakthrough study will show the dysgenic devolution found in many species of animals, primates and even different classes and races of people. With this report, science will now come closer than ever to finding the lineage of mankind. We will start with dysgenic degenerate brachycephalic conditions found in racial ethnic populations of Negros, Orientals, Jews and Hispanics}.


---------------------------



Example sentences from Wikipedia that use the word brachycephalic
 
 http://www.rhymezone.com/r/rhyme.cgi?loc=ol_ue&typeofrhyme=wke&Word=brachycephalic
 
 


Bostons are brachycephalic breeds.
Boston Terrier
They were described as tall, heavy boned and brachycephalic.
Beaker culture
The head is broad, massive, square, and powerful brachycephalic shape.
Perro de Presa Canario
A typical Alpine skull is therefore regarded as brachycephalic ('broad-headed').
Alpine race
Brachycephalic dogs such as Boxers and Boston Terriers are most commonly affected.
Cleft lip and cleft palate
It is seen in brachycephalic (short-nosed) dog breeds because of the shallow orbit.
Exophthalmos
The modern brachycephalic Persian has a large rounded skull and shortened face and nose.
Persian cat
The Japanese Chin's flattened brachycephalic face can lead to breathing and eye problems.
Japanese Chin
It is commonly seen in Boxer dogs and other brachycephalic breeds, and in the English Springer Spaniel.
Gingival enlargement
The long, broad, flat head of the Alaunt should never be confused with the modified brachycephalic breeds.
Alaunt
Brachycephalic syndrome is a common problem and mostly affects dogs with short noses (brachycephalic breeds).
Shih Tzu
A typical brachycephalic molossoid type breed, the Bordeaux is a very powerful dog, with a very muscular body.
Dogue de Bordeaux
Like all brachycephalic, or "short faced", breeds, Bulldogs can easily become overheated and even die from hyperthermia.
Bulldog
Several air carriers embargo certain dog breeds, due to the effect of high temperature and humidity on brachycephalic animals.
Pit bull
Human populations were characterized as either dolichocephalic (long headed), mesaticephalic (moderate headed), or brachycephalic (short headed).
Cephalic index
Following the deaths of Pugs and other brachycephalic breeds, several airlines either banned their transport in cargo or enacted seasonal restrictions.
Pug
Wolves and other wild dogs are dolichocephalic or mesaticephalic, but some domesticated dogs have become brachycephalic (short-headed) due to artificial selection by humans over the course of 12,000 years.
Sighthound
...however, puggles can occasionally have the respiratory ailments commonly found in Pugs (a breed known for being brachycephalic).
Puggle
...long and thin (dolichocephalic), as in the Rough Collie, to nearly nonexistent because it is so flat (extreme brachycephalic), as in the Pug.
Snout
...backwards sneezing or inspiratory paroxysmal respiration) is a phenomenon observed in dogs, particularly in those with brachycephalic skulls.
Reverse sneezing
Boxers are brachycephalic (they have broad, short skulls), have a square muzzle, mandibular prognathism (an underbite), very strong jaws, and a...
Boxer (dog)
...populations have been characterized as either dolichocephalic (long headed), mesaticephalic (moderate headed), or brachycephalic (short headed).
Brachycephaly
As they are a brachycephalic breed (see Brachycephalic syndrome), French Bulldogs are banned by several commercial airlines due to the numbers that have died while in the...
French Bulldog
Other differences in head shape between brachycephalic and dolichocephalic dogs include changes in the craniofacial angle (angle between the basilar axis and hard palate) (...
Dog anatomy
...tint to an olive shade, with black and coarse hair with a circular cross section, an absent or scanty beard, a brachycephalic skull, prominent cheek bones and a broad face.
Mongoloid
Other differences in head shape between brachycephalic and dolichocephalic dogs include changes in the craniofacial angle (angle between the basilar axis and hard palate) (...
Evolution of the wolf
...Aryan and his Social Role", in which he claimed that the white, "Aryan race", "dolichocephalic", was opposed to the "brachycephalic" race, of whom the "Jew" was the archetype.
Racism



-----------------------


How the Asian face got its unique characteristics

https://www.scmp.com/infographics/article/2100532/how-asian-face-got-its-unique-characteristics

{One theory is that Orientals have larger skulls, and that part of their heads are flatter to
accommodate a larger skull. The reason why Orientals have bigger heads is that Orientals are actually part Denisovan}.


-------------


What makes Asian eyes look different?

https://eyemd.wordpress.com/2006/09/01/what-makes-asian-eyes-look-different/


-----------


ELI5: How did humans in Asia evolve to have narrower eyes, why did Africans skin stay black while Arabic and European peoples became lighter?

https://www.reddit.com/r/explainlikeimfive/comments/1kqquy/eli5_how_did_humans_in_asia_evolve_to_have/


-----------


Images of 20 Chinese women before and after plastic surgery draw eyes online

http://shanghaiist.com/2014/11/10/20-women-before-after-plastic-surgery/


-----------


ORIGIN OF SHAPE OF ASIAN EYES IS STILL A MYSTERY TO SCIENTISTS


https://www.chicagotribune.com/news/ct-xpm-1985-10-13-8503100141-story.html


-----------


Epicanthic fold

https://en.wikipedia.org/wiki/Epicanthic_fold



Medical conditions

The epicanthic fold is sometimes found as a congenital abnormality. Medical conditions that cause the nasal bridge not to mature and project are associated with epicanthic folds. About 60% of individuals with Down syndrome (also known as trisomy 21) have prominent epicanthic folds. In 1862, John Langdon Down classified what is now called Down syndrome. He used the term mongoloid for the condition. This was derived from then-prevailing ethnic theory and from his perception that children with Down syndrome shared physical facial similarities (epicanthic folds) with those of Blumenbach's Mongolian race. While the term "mongoloid" (also "mongol" or "mongoloid idiot") continued to be used until the early 1970s, it is now considered pejorative and inaccurate and is no longer in common use about medical conditions.

In Zellweger syndrome, epicanthic folds are prominent. Other examples are fetal alcohol syndrome, phenylketonuria, and Turner syndrome.

Possible evolutionary function

The epicanthic fold is often associated with greater levels of fat deposition around the eyeball, a feature most accentuated in native North Siberian, Aleut and Inuit populations. The adipose tissue is thought to provide greater insulation for the eye and sinuses from the effects of cold, especially from freezing winds, and to represent an adaptation to cold climates. It has also been postulated that the fold itself might provide a level of protection from snow blindness. Though its appearance in peoples of Southeast Asia can be linked to possible descent from cold-adapted ancestors, its occurrence in various African peoples precludes a cold-adaptive explanation for it appearing in the latter groups. The epicanthic fold found in some African people has been tentatively linked to protection for the eye from the high levels of ultra-violet light found in desert and semi-desert areas.

Age

Many fetuses lose their epicanthic folds after three to six months of gestation. Epicanthic folds may be visible in the development stages of young children of any race, especially before the nose bridge fully develops.


---------------



 Massive rise in Asian eye damage

4 May 2012

https://www.bbc.com/news/health-17942181

Up to 90% of school leavers in major Asian cities are suffering from myopia - short-sightedness - a study suggests.

Researchers say the "extraordinary rise" in the problem is being caused by students working very hard in school and missing out on outdoor light.

The scientists told the Lancet that up to one in five of these students could experience severe visual impairment and even blindness.


--------------------------------------



Characteristic ocular findings in Asian children with Down syndrome

November 2002

https://www.nature.com/articles/6700208

 


--------------------------------------



Neutral non offensive alternative to “slanting eyes”

https://english.stackexchange.com/questions/321685/neutral-non-offensive-alternative-to-slanting-eyes




--------------------------------------


The Evolution of Looks and Expectations of Asian Eyelid and Eye Appearance

2015

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536060/


---------------------------------------



Caucasians and Asians don't examine faces in the same way

2010

https://www.sciencedaily.com/releases/2010/01/100126111953.htm


----------------------------------------


13 Asians On Identity And The Struggle Of Loving Their Eyes

2017

“I used to use Scotch tape to make my eyes bigger. Then I said, ‘Hey, this is your face. This is how you look.’”

https://www.huffpost.com/entry/asian-american-eyes-photos_n_59f79448e4b0aec1467a3270


---------------------------------------


Palpebral slant - eye

The palpebral slant is the direction of the slant of a line that goes from the outer corner of the eye to the inner corner.

https://medlineplus.gov/ency/article/003316.htm


----------------------------------------




Slant eye

https://www.urbandictionary.com/define.php?term=slant%20eye



----------------------------------------


Slanty eyes

https://www.urbandictionary.com/define.php?term=slanty%20eyes


-----------------------------------------


Why do people have different eye shapes?

https://www.sciencefocus.com/the-human-body/why-do-people-have-different-eye-shapes/


-----------------------------------------


What was the evolutionary advantage of the slanted eye shape for asians?

https://www.reddit.com/r/AskAnthropology/comments/ar9krp/what_was_the_evolutionary_advantage_of_the/


-----------------------------------------



 The Asian Eyelid: Relevant Anatomy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536062/



------------------------------------------



Why Do Chinese People Have Slanted Eyes?

https://www.asymptotejournal.com/special-feature/amanda-lee-koe-why-do-chinese-people-have-slanted-eyes/


Professor of the Department of Biological Anthropology, speaking slowly at a Neo-Mongoloid Evolutionary Processes lecture. Cambridge, Massachusetts, United States of America.

A matter of periocular anatomy. It isn't just the eyes per se we are talking about—there's the flatter nose, the lower-based nasal bridge, the higher amount of preaponeurotic fat in the epicanthic fold. More precisely, the orbital septum fuses to the levator aponeurosis at variable distances below the superior tarsal border, and there is no extension of the capsulopalpebral fascia.

By the by, to term it "Chinese" eyes isn't quite accurate, for the condition isn't unique to the Chinese, but a definitive racial trait of the Mongoloids—though the word is pejorative now, it was utilised in early ethnology and we still use it in academic formality; we mean no harm, but things move so slowly here. We're talking Siberian, North Mongoloid, Central Mongoloid, South Mongoloid, Indonesian, Polynesian, Eskimo, and Amerindian.

The epicanthic fold was one of several adaptations to the cold, the bitter conditions of the Mammoth steppe during the Middle Pleistocene, some 600,000 to 370,000 years ago. The others: short limbs, flat faces, short noses, lower surface to mass ratio, cyclical vasodilation, and vasoconstriction of the peripheral capillaries.



----------------------------------------





{The Chinese have slanted eyes because they are a Deniosvan subspecies that ended up having a bracycephalic deformity in their faces.
 If Orientals eyes were to slant any further, Orientals simply would not be able to live as a species from too many eye and nasal problems being caused by this brachycephalic condition of degenerating with these slanted eyes. This is also why Asians have many vision problems and many are also bad drivers. The big question is why Asians eyes slanted more than other races. We all know part of the reason is that Orientals were a subspecies of Denisovans and possibly Homo erectus. Many question if Orientals faces deformed further with brachycephalic slanting of the eyes over a period of time with evolution, or if a larger head was inherited by Orientals from being part Denisovan}.




----------------------------------------




Asian eyelid morphologies are categorized into six types.


https://www.researchgate.net/figure/Asian-eyelid-morphologies-are-categorized-into-six-types-A-Single-eyelid-no-visible_fig1_281469924









Asian eyelid morphologies are categorized into six types. (A) Single eyelid (no visible lid crease). (B) Low eyelid crease (low-seated, nasally tapered, including hidden fold). (C) Double eyelid crease, infold type: the height of the upper lid crease is lower than the epicanthal fold. (D) Double eyelid crease, on fold type: the height of the crease is right on the epicanthal fold. (E) Double eyelid crease, outfold type: the height of the crease is higher than the epicanthal fold (asterisk). (F) Double eyelid crease, outfold type without an epicanthal fold.





------------------------------



East Asian Physical Traits Linked to 35,000-Year-Old Mutation

https://www.nytimes.com/2013/02/15/science/studying-recent-human-evolution-at-the-genetic-level.html


------------------------------


Evaluating hypercoagulability (abnormal blood coagulation that increases the risk of blood clots) in dogs with brachycephalic airway syndrome: similarity to human obstructive sleep apnea.

2017

http://news.vet.tufts.edu/2017/02/evaluating-hypercoagulability-abnormal-blood-coagulation-that-increases-the-risk-of-blood-clots-in-dogs-with-brachycephalic-airway-syndrome-similarity-to-human-obstructive-sleep-apnea/



-------------------------------



Sleep disturbances are common, influenced by race and ethnicity

High prevalence of sleep disturbances, undiagnosed sleep apnea among racial/ethnic minorities may contribute to health disparities

https://www.sciencedaily.com/releases/2015/06/150619141605.htm



--------------------------------



Disparities and Genetic Risk Factors in Obstructive Sleep Apnea

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602395/

Abstract

Obstructive sleep apnea (OSA) is an increasingly prevalent condition. A growing body of literature supports substantial racial disparities in the prevalence, risk factors, presentation, diagnosis and treatment of this disease. Craniofacial structure among Asians appears to confer an elevated risk of OSA despite lower rates of obesity. Among African Americans, Native Americans, and Hispanics, OSA prevalence is increased, likely due in part to obesity. Burden of symptoms, particularly excessive daytime sleepiness, is higher among African Americans, though Hispanics more often report snoring. Limited data suggest African Americans may be more susceptible to hypertension in the setting of OSA. While differences in genetic risk factors may explain disparities in OSA burden, no definitive genetic differences have yet been identified. In addition to disparities in OSA development, disparities in OSA diagnosis and treatment have also been identified. Increased severity of disease at diagnosis among African Americans suggests a delay in diagnosis. Treatment outcomes are also suboptimal among African Americans. In children, tonsillectomy is less likely to cure OSA and more commonly associated with complications in this group. Among adults, adherence to continuous positive airway pressure (CPAP) is substantially lower in African Americans. The reasons for these disparities, particularly in outcomes, are not well understood and should be a research priority.


Background

Obstructive sleep apnea (OSA) is one of the most prevalent sleep disorders with moderate to severe disease affecting up to 17% of middle-aged men and 9% of middle-aged women. OSA is associated with numerous adverse consequences including excessive daytime sleepiness, motor vehicle accidents, hypertension and cardiovascular disease. A large body of literature has identified risk factors for OSA, consequences of the disease and treatment options. However, studies evaluating the extent to which the development, presentation, consequences and management of OSA vary by race have not been as extensively considered. This article will review known differences in OSA by racial background as well as point out areas where further research is needed.


Disparities in OSA Prevalence

Few studies have directly compared the prevalence of OSA across racial groups. In addition, the lack of consistent criteria to define OSA limits comparisons of OSA prevalence across studies. Nevertheless, available data indicate an elevated prevalence of OSA among African Americans, Hispanics, and Native Americans as compared to US whites while the prevalence of OSA in Asians appears comparable to whites.

The strongest evidence for a racial disparity in OSA exists with regards to African Americans. Several studies have found a higher rate of OSA in African Americans particularly African American children.3 Among pediatric patients evaluated in sleep clinic, African American race is associated with a 20% increase in OSA severity4 and greater oxygen desaturation. African American children are 4-6 times more likely to have OSA compared to white children. Even among young adults less than 26 years of age, African Americans are 88% more likely to have OSA as compared to whites. Among middle-aged populations, the evidence for a disparity in OSA prevalence is weaker as differences in OSA prevalence from community based studies are evident in some but not all studies. In contrast, data from older populations suggests a disparity may re-emerge in this age group. While African Americans had similar prevalence of OSA as whites (32% and 30% respectively) in a community-based survey of individuals 65 years of age and older, this group was 2.1 times more likely to have severe OSA.

Data are somewhat more limited regarding OSA prevalence in US Hispanics. The Hispanic Community Health Study (HCHS) used portable sleep monitoring to evaluate the prevalence of OSA in a diverse US Hispanic cohort of over 14,000 adults. The prevalence of mild, moderate and severe OSA in this cohort was 25.8%, 9.8%, and 3.9% but OSA risk was found to vary substantially by Hispanic background being greatest among Cuban men. Consistent with other racial groups, older age, male gender, and obesity were independent risk factors for OSA in this cohort. Although the prevalence is somewhat greater than estimates of community-based white populations, the monitoring system used is very different making direct comparisons difficult.

A cross-racial survey utilizing overnight oximetry, however, did find a higher rate of OSA in Hispanics compared to whites. In contrast, an analysis of data from one site of the Multi-Ethnic Study of Atherosclerosis (MESA) found that the rate of OSA in Hispanics was similar to whites. However, a more recent analysis evaluating subjects at all MESA sites has reported a higher prevalence in Hispanics.

Information about OSA in Native Americans is sparse. The best evidence comes from SHHS where the odds of moderate to severe OSA was 1.7 times greater than that found in whites.

Unlike African Americans, Hispanics and Native Americans, the prevalence of OSA in Asians and Asian Americans appears similar or lower than that of whites. In a cross-study analysis comparing Japanese participants in the Circulatory Risk in Communities Study (CRICS) to whites in MESA, the prevalence of OSA among Japanese was roughly half that of whites (18.4% vs. 36.5%).15 However, in other studies, Asians have been found to have similar OSA severity to whites. In the Male Study of Osteoporosis (MrOS) cohort of older men, Asian American background was an independent risk factor for OSA. This is consistent with population-based studies from Asia where high rates of OSA have been found in China, Japan, Korea and India, despite low rates of obesity.

In summary, current data from population-based studies suggest the prevalence of OSA is greater among African Americans, Hispanics, and Native Americans although direct comparisons particularly for Hispanics and Native Americans compared to other groups are limited. The greater prevalence in African Americans is particularly notable in younger and older age groups. Asians and Asian Americans appear to have comparable rates of OSA to whites despite markedly lower levels of obesity.

OSA Risk Factors

Understanding the basis of disparities in OSA prevalence requires an evaluation of disparities in the risk factors for OSA as well as an assessment of racial heterogeneity in how risk factors contribute to OSA pathogenesis. Among the most studied OSA risk factors are craniofacial shape and obesity.

Craniofacial shape

Craniofacial shape has been recognized as an important contributor to OSA risk. Both skeletal features such as maxillary-mandibular shape, inferior hyoid position, and small cranial base, as well as soft tissue features such as size of the tongue, soft palate, tonsils, pharyngeal walls, and parapharyngeal fat pads have been identified as OSA risk factors. In general, studies suggest soft tissue factors may be more relevant to predicting risk in African Americans while skeletal features are more predictive in Asians.

Studies comparing African Americans to whites have found tongue area is significantly larger in African Americans with OSA. In contrast, skeletal features such as brachycephaly (a skull shape with a greater lateral compared to antero-posterior dimension) were predictors of OSA severity in whites but not African Americans.26 In contrast, Asians with OSA have more skeletal restriction than their white counterparts as measured by a shorter cranial base as well as difference in length and positioning of the maxilla and mandible. In addition, both an inferiorly positioned hyoid and an extended craniocervical angle have been demonstrated to predict OSA risk in Asians.28,29 However, it is important to note that heterogeneity does exist across Asian backgrounds in the relationship between craniofacial risk factors and OSA.

As compared to African Americans and Asians, there is much sparser data on the relationship between craniofacial shape and OSA risk in Hispanics and Native American groups. Only a few studies have evaluated differences in craniofacial shape between Hispanics and whites that could contribute to differences in OSA risk and these have been inconclusive. One study found bi- maxillary retroposition to be more common among Hispanics with OSA than apneics of other races,33 however another study did not find any differences between Hispanics and whites. Table 1 summarizes the contributing soft tissue and skeletal contributors to OSA, with racial differences noted where literature is available.



------------------



Brachycephalic Airway Syndrome

https://www.sciencedirect.com/science/article/pii/S0195561692503060



--------------------------



Do Indo-Asians have smaller coronary arteries?

https://pmj.bmj.com/content/75/886/463



-------------------------



Asians look thinner but are fatter than Westerners


SINGAPORE: Asians may look thinner than Westerners but they have more fat in their bodies, health experts told a World Health Organisation (WHO) forum yesterday. Obesity is less of a problem in Asia compared with the West, but Asians experience higher cases of obesity-related diseases, they said.


For example, Singaporeans have 5% more body fat than Caucasians, said Mabel Yap, director for research and information management at Singapore''s Health Promotion Board.

"What this means is, we are fatter though we look thinner," she said.

The latest National Health Survey in 1998 found that only 6% of Singaporeans were obese, compared with 5% in 1992.

But the number of Singaporeans with obesity-related diseases was comparable to levels in the West.

While those with diabetes remained at 8%, 27% suffered from high blood pressure while 23.5% had high cholesterol levels, according to the 1998 survey.

http://nutriweb.org.my/index.php?asians-look-thinner-but-are-fatter-than-westerners_del-20101229194745



-------------------------



The Skinny: Asians are the thinnest Americans but that doesn't mean they're the healthiest

    Only 38.6 per cent of Asian Americans are overweight compared to 66.7 per cent of whites and 78.8 per cent for Hispanics
    Younger people are more likely to be thinner than older people and since Asian Americans are a young minority in America, that could account for their slimness
    Asians are just as likely to have high cholesterol or hyper tension as other groups

https://www.dailymail.co.uk/news/article-2540332/The-Skinny-Asians-thinnest-Americans-doesnt-mean-theyre-healthiest.html


----------------------


Do Asian Women Have the Smallest Breasts?

http://www.8asians.com/2011/04/01/do-asian-women-have-the-smallest-breasts/


-----------------


Mongoloid

https://en.wikipedia.org/wiki/Mongoloid


------------------------


Why Asians are thinner: On Cultural Reduction and Health (Contains offensive language)

https://evidencebasedfitness.net/why-asians-are-thinner-on-cultural-reduction-and-health/


------------------------


{There are several theories to why Orientals are thinner, one reason is that Orientals are
part Denisovan.


It could have been genetics, lack of food, climate or other factors to why Orientals are some
of the smallest people on the planet.


Look at how in Tibet there is very little food, and people there do not grow as big on average compared to white Europeans or black Africans. In many areas of Tibet people can starve
to death in these conditions, and that people learn to adapt with a less amount of food than other people in other areas of the world}.


---------------------


Ectodysplasin A receptor

https://en.wikipedia.org/wiki/Ectodysplasin_A_receptor

Ectodysplasin A receptor (EDAR) is a protein that in humans is encoded by the EDAR gene. EDAR is a cell surface receptor for ectodysplasin A which plays an important role in the development of ectodermal tissues such as the skin. It is structurally related to members of the TNF receptor superfamily.


Function


EDAR and other genes provide instructions for making proteins that work together during embryonic development. These proteins form part of a signaling pathway that is critical for the interaction between two cell layers, the ectoderm and the mesoderm. In the early embryo, these cell layers form the basis for many of the body's organs and tissues. Ectoderm-mesoderm interactions are essential for the proper formation of several structures that arise from the ectoderm, including the skin, hair, nails, teeth, and sweat glands.

Clinical significance

Mutation in this gene have been associated with hypohidrotic ectodermal dysplasia, a disorder characterized by a lower density of sweat glands.

Derived EDAR allele

A derived G-allele point mutation (SNP) with pleiotropic effects in EDAR, 370A or rs3827760, found in most modern East Asians and Native Americans but not common in African or European populations, is thought to be one of the key genes responsible for a number of differences between these populations, including the thicker hair, more numerous sweat glands, smaller breasts, and the Sinodont dentition (so-called shovel incisors) characteristic of East Asians. It has been hypothesized that natural selection favored this allele during the last ice age in a population of people living in isolation in Beringia, as it may play a role in the synthesis of breast milk under Vitamin D-poor conditions. The 370A mutation arose in humans approximately 30,000 years ago, and now is found in 93% of Han Chinese and in the majority of people in nearby Asian populations. This mutation is also implicated in ear morphology differences and reduced chin protrusion. The derived G-allele is a mutation of the ancestral A-allele, the version found in most modern non-East Asian and non-Native American populations.

In a 2015 study, three (of six) ancient DNA samples (7,900-7,500 BP) from Motala, Sweden; two (3300–3000 BC) from the Afanasevo culture and one (400–200 BC) Scythian sample were found to carry the rs3827760 mutation.

In a 2018 study, several ancient DNA samples from the Americas, including USR1 from the Upward Sun River site, Anzick-1, and the 9,600 BP individual from Lapa do Santo, were found to not carry the derived allele. This suggests that the increased frequency of the derived allele occurred independently in both East Asia and the Americas.



--------------------------



Thick Hair, Small Boobs, Shovel Shaped Teeth and More

https://dna-explained.com/2013/02/17/thick-hair-small-boobs-shovel-shaped-teeth-and-more/


Posted on February 17, 2013   

Yep, there’s a gene for these traits, and more.  The same gene, named EDAR (short for Ectodysplasin receptor EDARV370A), it turns out, also confers more sweat glands and distinctive teeth and is found in the majority of East Asian people.

This is one of the results of the National Geographic’s Genographic project.  This mutation found at location rs3827760 on chromosome 2 occurred about 35,000 years ago.  It apparently has conferred some advantage to its carriers, because it is found in the majority of Asian people today.  We don’t exactly know why that happened, but maybe ancient male Asians preferred thick haired, small boobed and sweaty women.  Or maybe those women survived when women with more body fat (yes, boobs are fat, sorry guys) and who could sweat less perished.

This New York Times article discusses the experiments performed to verify that this gene in fact does confer those traits.  The scientific article itself is available in the journal, Cell although it’s behind a paywall.


------------------


{We see a higher rate of Sotos Syndrome in Japanese people. Could this be one of the reasons why we often see Orientals with enlarged heads, flat faces, including many of the symptoms associated with Sotos Syndrome?


Many say that the brachycephalic problems in Orientals could be from a very slight similar form of a type of Sotos Syndrome that was passed on genetically through generations.

We notice that this may also be one of the reasons why some black people also have many of the genetic problems associated with Sotos Syndrome as well, this would also give a reason to why black infants grow faster after birth than other races of infants. The reason why some blacks learn to walk sooner than other races is because blacks are part animal, most animals learn to walk sooner than a human. We question if a Homo heidelbergensis or a Homo erectus could learn to walk sooner than a human.


 We can still see that the west has some of the best high IQ inventors such as Tesla, Da Vinci and the Germans that made the nuclear bomb}.




--------------------



 What You Should Know About Sotos Syndrome

 
https://www.healthline.com/health/sotos-syndrome

 

Physical and physiological symptoms of Sotos syndrome in babies include:

    being a large baby at birth
    growing quickly after birth
    jaundice
    poor feeding

 In children, such symptoms include:

    being taller and bigger than peers of the same age
    large head
    large hands and feet
    long and narrow face
    high forehead
    red or flushed cheeks
    small and pointy chin
    weak muscle tone
    down-slanting eyes
    hypertelorism, which means having a large distance between the eyes
    awkward gait, or way of walking
    scoliosis
    seizures
    hearing loss
    kidney and heart problems
    vision problems


 Mental and developmental symptoms of Sotos syndrome in children include:

    learning disabilities
    delayed development
    behavioral problems
    speech and language problems
    aggressiveness and irritability
    clumsiness
    attention deficit hyperactivity disorder (ADHD)
    motor skill problems

 Risk factors of this condition

Soto's syndrome occurs in 1 out of 14,000 births. This condition is more common among people who are Japanese or of Japanese heritage.



--------------------



How Japanese and Belgian Sweat Differ

https://nippaku.wordpress.com/2013/07/25/how-japanese-and-belgian-sweat-differ/



--------------------



Do Asians Sweat More?

http://www.8asians.com/2013/03/20/do-asians-sweat-more/


--------------------



Characterization of the Asian Phenotype - An Emerging Paradigm with Clinicopathological and Human Research Implications

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562114/


---------------




The mitogenome of a 35,000-year-old Homo sapiens from Europe supports a Palaeolithic back-migration to Africa

https://www.nature.com/articles/srep25501


----------------


Psychologists find Asian Americans get a social boost from being overweight

https://qz.com/1048804/psychologists-find-asian-americans-get-a-social-boost-from-being-overweight/


-------------------


Why do Asians have bigger brains than Europeans or Africans?

Chinese scientists discover natural selection played a role

https://www.scmp.com/news/china/article/2054126/why-do-asians-have-bigger-brains-europeans-or-africans


--------------------


Genetics

Canine brain tumors as a platform for discovery:

https://www2.vetmed.ucdavis.edu/Neurology/Research/PetersonGenetics.html


------------------




Why Summer Heat Can Be Deadly To Brachycephalic Dogs

https://dogtime.com/dog-health/53229-summer-heat-can-deadly-brachycephalic-dogs



----------------


Two weeks in the mountains can change your blood for months

https://www.sciencemag.org/news/2016/10/two-weeks-mountains-can-change-your-blood-months


--------------


What is Low Blood Oxygen?


https://wagwalking.com/cat/condition/low-blood-oxygen


{Some brachycephalic kinds of cats have more low blood oxygen than other cats}.


-----------------


 Brachycephalic Syndrome in Cats


 https://wagwalking.com/cat/condition/brachycephalic-syndrome

 What is Brachycephalic Syndrome? Brachycephalic syndrome may involve several upper airway abnormalities. Cats with this health issue may have an elongated soft palate, stenotic nares (narrow, pinched nostrils), and everted laryngeal saccules (small sacs in the larynx that turn out). All of these obstruct normal air flow. Some cats may also have narrowed tracheas or hypoplastic tracheas. Cats that develop brachycephalic syndrome typically have shortened skull bones and short, pushed-in noses. “Brachycephalic” comes from two words, with “brachy” meaning


Symptoms of Brachycephalic Syndrome in Cats


 The cat with brachycephalic syndrome shows several characteristic symptoms that all combine to make breathing difficult: Mouth breathing Noisy breathing Snoring Labored breathing Snorting noises Fainting after exertion Tiring with physical activity Restlessness Coughing and gaging Frequent retching or vomiting Cyanosis Worsening symptoms during hot weather Because of the cat’s facial features and breathing issues, it may also have additional symptoms and issues: Difficulty swallowing Higher risk of heat stroke Dental and periodontal disease Skin infections in the folds of its face Abnormal body posture from attempts to breathe more efficiently Eye problems


Causes of Brachycephalic Syndrome in Cats



Brachycephalic syndrome has only a few causes: Cats that are bred to have shortened faces Narrowed nostrils Long soft palate Turned-out laryngeal saccules Hypoplastic (narrower than normal) trachea Breeders prefer this shortened head shape in several cat breeds, but this leads to significant health issues for those cats.


Diagnosis of Brachycephalic Syndrome in Cats


Once a cat has begun to display symptoms, it can be easy for the vet to develop a diagnosis, but they will still want to run several diagnostic tests to make sure it is correct. The vet may recognize the cat’s appearance and ask about any unusual symptoms the owner may have noticed, such as fainting, noisy breathing or difficulty breathing. Vets know that certain purebred cats are more likely to have been bred to have the shortened face. Knowing this, they will examine the cat, noting its facial characteristics. The vet will also visually inspect the cat’s palate and look for the turned-out laryngeal sacs. This may need to be done while the cat is under anesthesia. Because cats with brachycephalic syndrome don’t always tolerate anesthesia well, the vet will order chest X-rays and blood work to determine the cat’s overall health before beginning anesthesia. While the cat is under anesthesia for the diagnostic work, the vet will also recommend that surgery be done at the same time. By combining the diagnostic work and surgery into one procedure, this reduces the risk to the cat’s life. The vet will specifically look at the cat’s CO2 and pH levels when they order blood work. This helps them to understand the extent of the cat’s breathing problems. The cat may also undergo an endoscopic examination of the trachea and upper airway to see how severe the airways and trachea are affected by this syndrome. Finally, the vet orders bacterial cultures or a biopsy of the airway to identify any potential infections the cat may have.


Treatment of Brachycephalic Syndrome in Cats


Treatment of brachycephalic airway syndrome begins immediately because of its effects on the cat’s health and life. If the cat is overweight, the vet wants to see the cat can lose the unneeded weight. By losing excess pounds, the cat will find it easier to breathe and, eventually, to move around more easily. The cat may begin taking non-steroidal anti-inflammatory (NSAIDS) medications to help give short-term relief from respiratory distress and airway inflammation. Corticosteroids can give the cat the same type of relief from its symptoms. Oxygen therapy allows the cat to get more oxygen into its airways and body. These only help to manage symptoms, not correct their causes. Surgery is the best option to help the cat get needed, permanent relief. The veterinary surgeon widens the cat’s nostrils by removing a small wedge of tissue. The soft palate is shortened, making it much easier for the cat to breathe post-surgery. Finally, the turned-outward laryngeal sacs will be removed, further removing obstructions to the cat’s airway. The earlier the cat is diagnosed with brachycephalic syndrome and surgically treated, the better. This prevents the cat from developing other abnormalities related to its shortened face.

 



 

--------------------


‘We are all mutants now’: the trouble with genetic testing

https://www.theguardian.com/science/2017/jul/18/we-are-all-mutants-now-the-trouble-with-genetic-testing

-----------------

{Could a natural disaster activate a natural mutation gene that is already built into the genetic structure of humans}?

-----------------


African Americans at Increased Risk for Eye Diseases

Cataracts
Glaucoma
Diabetes
Hypertension

https://yoursightmatters.com/african-americr-eye-diseases/


------------------


Focus on Eye Health and Culturally Diverse Populations

http://www.visionproblemsus.org/downloads/2167_MultiCultiCompanion_v08_web.pdf

Myopia – Myopia, or trouble seeing far away, affects upwards of 80 percent of Asian Americans.



-----------------------------------


 {Here is an example of a dysgenic brachycephalic black man with bug-eyes}.



Man Pops Out Eyes

https://www.youtube.com/watch?v=YDIGDNQ-fbY



-----------------------------------



Stock Photo - Handsome bug-eyed African American male freelancer in shirt having forgetful face expression touching head with hand, realizing today is deadline of his project, opening mouth as if saying No!

https://www.123rf.com/photo_75999029_handsome-bug-eyed-african-american-male-freelancer-in-shirt-having-forgetful-face-expression-touchin.html



--------------------------------------


Flat Feline Faces: Is Brachycephaly Associated with Respiratory Abnormalities in the Domestic Cat (Felis catus)?

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161777


-------------------------------------


The Evolution of Petface


 https://www.smithsonianmag.com/science-nature/evolution-petface-180967987/


The same traits that make these dogs adorable threaten their health and well-being



Consider the French bulldog. On the plus side, this charismatic small dog is relatively low-maintenance, doesn’t need a lot of exercise and sticks close to its owner; for many, the makings of a perfect pet. But the health issues associated with brachycephaly, which refers to dog breeds that have wide and flat skulls, means that they often require a higher-than-average amount of veterinary treatment. Moreover, they are forced to rely on humans for things as simple as having their wrinkles cleaned out and giving birth.

The American Kennel Club, which oversees dog breeding standards in the United States, stipulates that Frenchies should have “bat ears” along with “heavy wrinkles forming a soft roll over the extremely short nose.” But those bat ears are prone to infection, as the AKC itself notes. Thanks to their short faces, “Frenchies have less tolerance of heat, exercise and stress, all of which increase their need to breathe,” the guide continues, advising that Frenchie owners keep their pets cool and avoid strenuous exercise. It also notes that the dog’s wrinkles “can be prone to yeast and bacterial infections,” and should be cleaned regularly.

This is just one example of how extreme breed conformation can affect dog welfare and increase the reliance of brachycephalic dogs on human intervention. Yet while it’s long been known that purebred dogs tend to suffer from body shapes and genetic conditions that hurt their health and limit their day-to-day existence, it’s only now that we’re beginning to understand the long history and scientific mechanisms behind this suffering.



How We Got Here

The purebred concept emerged in the Victorian period, when middle-class city dwellers started regularly keeping pets for themselves and their children, rather than just farm animals. Around this time, the eugenics movement preached that it was possible to breed “pure” and ideal animals and humans.

“The systematic breeding of dogs emerged in the middle of the nineteenth century,” writes animal welfare scientist James A. Serpell in Companion Animal Ethics. “Although there were already clearly distinguishable breeds of dogs and other domestic animals before this, the new trend was characterised by conscious efforts to ‘improve’ domestic animals through controlled breeding.” While eugenics is now looked down upon in humans, it’s in many ways alive and well in the pet world. The ideal of “purebred” dogs as being somehow more valuable and desirable is still upheld by kennel clubs, breeders and those who buy them, says Bonnett.


---------------------------


Headform and human evolution

https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC1272824&blobtype=pdf


---------------------------


Brachycephaly – What You Need to Know?



What is Brachycephaly?

A brachycephalic skull is flat in the rear. The head is also often taller in the back than in the front, the baby’s face may be wider than average, and his or her ears may stick out. The condition frequently occurs in combination with plagiocephaly, and is nearly always the result of positioning of the head of the baby, where pressure is placed on the back of the head for prolonged periods.
What Causes Brachycephaly?

Congenital

Sometimes brachycephaly is a congenital condition, which means it exists at or before birth. According to the National Institutes of Health’s NINDS, brachycephaly occurs when the front bone and side bones join together before the skull is fully developed. There are numerous potential causes for brachycephaly, including metabolic, genetic and developmental disorders. If your child is diagnosed with congenital brachycephaly, make sure that they are evaluated for any associated conditions that your doctor believes are potentially to blame.

Brachycephaly Risk Factors

Risk factors for congenital brachycephaly are predominantly thought to be genetic, although many cases develop in babies with no family history of brachycephaly. As a result, the study of brachycephaly is a popular area of research at present.

The risks for developing the acquired form of brachycephaly include all of the observed risk factors for plagiocephaly, as well as carrying low in the pelvis during pregnancy, very large birth size (macrosomia), breech birth, and being born to a mother with a bicornuate uterus.


https://www.babyflathead.org/brachycephaly-what-you-need-to-know/


---------------


Brachycephalic, dolichocephalic and mesocephalic: is it appropriate to describe the face using skull patterns?

https://www.semanticscholar.org/paper/Brachycephalic%2C-dolichocephalic-and-mesocephalic%3A-Franco-Ara%C3%BAjo/60b4a1bec6c979243168c2806fbb1b0a2c8242c0


The use of a standardized terminology in the medical sciences is essential for both clinical practice and scientific research. In addition to facilitating communication between professionals, it enhances the reliability of comparisons made between studies from different areas, thereby contributing to a higher level of scientific evidence. Examples of attempts made to standardize the terminology in other areas dedicated to the study of craniofacial morphology can be found in the literature. On the other hand, one can find in the orthodontic literature a variety of terms that render the consensus and communication between orthodontists and other researchers even more problematic. As an example, one could cite the use of the terms brachyfacial, mesofacial and dolichofacial, which form part of a cranial index terminology used to describe facial types. Thus, a reflection on the origin and differences of the terms used to describe the human facial phenotype may pave the way toward a consensus regarding the meaning that best represents the craniofacial patterns.


-------------



Study: Genetic Mutation Linked to Brachycephaly in Dogs


 https://www.petguide.com/blog/dog/study-genetic-mutation-linked-to-brachycephaly-in-dogs/


Flat faces on Bulldogs and Pugs are cute, but they can lead to breathing problems. New research shows that those faces are linked to a genetic mutation in dogs and their skull development.

Researchers from the Roslin Institute at the University of Edinburgh have studied DNA samples of almost 400 dogs. They believe they’ve found a genetic mutation that shapes the flat faces of breeds like Boxers, Bulldogs and Pugs. The researchers think that this finding also may give insight into birth defects in human children with regard to their head development while in the womb.

Related: UK Vets Warn Against Owning Flat-Faced Breeds

The dogs in the study were pedigreed and mixed breed, and had body scans that gave the scientists access to 3-dimensional images of their heads. They took measurements of the dogs’ skulls and were able to compare those measurements with genetic information. They noted specific DNA variations that they correlated with different head shapes.

They found that a variation in the gene SMOC2 was linked to the length of a dog’s face. When there was a mutated development of that gene, the animals with that mutation were found to have much flatter faces than other canines. This flat face is also known as brachycephalic, and can cause significant health issues in those affected.

Dr. Jeffrey Shoenbeck, lead researcher, says that this finding is important as it gives more information on the genetic and molecular composition that goes into skull formation in dogs and humans.


Humans can be born brachycephalic as well, and the researchers now believe that based on their connections, screening of the SMOC2 gene in humans can bring a diagnosis of brachycephaly in children.

Many dogs are specifically bred for their brachycephalic attributes, though more and more veterinarians caution about doing so because of the extensive breathing problems that result from this breeding.



--------------



Here's Why Brachycephalic Dogs Such As Pugs And Bulldogs Have Flat Face

https://www.techtimes.com/articles/208570/20170530/heres-why-brachycephalic-dogs-such-as-pugs-and-bulldogs-have-flat-face.htm


--------------------


Dog skull study reveals genetic changes linked to face shape


The research reveals new insights into the genes that underpin skull formation in people and animals.

Scientists say their findings also shed light on the causes of birth defects that affect babies' head development in the womb.

Researchers at the University of Edinburgh's Roslin Institute analysed DNA samples from 374 pet dogs of various pedigree and mixed breeds. The dogs were being treated at the Royal (Dick) School of Veterinary Studies.

All of the animals underwent body scans as part of their care, producing detailed 3-dimensional images of the dogs' heads.

These high-resolution images -- called CT scans -- enabled the researchers to take precise measurements of the shape of the dog's skull.

By comparing the dogs' genetic information with measurements of their skulls, the team were able to pinpoint DNA variations that are associated with different head shapes.

One variation -- found to disrupt the activity of a gene called SMOC2 -- was strongly linked to the length of the dog's face. Animals with the mutation had significantly flatter faces, a condition called brachycephaly.

Babies are sometimes born with brachycephaly too, though little is known about its causes. Scientists say screening children for changes in the SMOC2 gene could help to diagnose the condition.

The study is published in the journal Current Biology.

Lead researcher Dr Jeffrey Schoenebeck, of the University's Roslin Institute, said: "Our results shed light on the molecular nature of this type of skull form that is so common and popular among dogs."


https://www.sciencedaily.com/releases/2017/05/170526125730.htm


---------------------


Why are the backs of Asian babies' heads flat?

https://www.quora.com/Why-are-the-backs-of-Asian-babies-heads-flat


----------------------------


Scientists have discovered a mutation behind pugs’ weird little flat faces

Not cute

https://www.theverge.com/2017/5/28/15703688/pugs-bulldogs-boston-terriers-squished-flat-faces-brachycephalic-genetics


----------------------

The Relationship between Brachycephalic Head Features in Modern Persian Cats and Dysmorphologies of the Skull and Internal Hydrocephalus

 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598898/

 

-------------------------

Severe brachycephalic in Persian and related breeds

https://icatcare.org/advice/cat-health/brachycephalic

-----------------------

Putting our heads together: Canines may hold clues to human skull development

 https://www.sciencedaily.com/releases/2013/02/130208105303.htm

----------------------


Brachycephalic Dogs: Why Do Pugs Breathe So Loudly

https://www.puglifemagazine.com/single-post/Brachycephalic-Dogs

 

-------------------------


Vision in Dogs

http://www.rctn.org/bruno/animal-eyes/dog-vision-miller-murphy.pdf



--------------

Study Finds Hispanic- and African-American Preschoolers Need Better Vision Screening

 https://www.aao.org/eye-health/news/hispanic-african-american-preschoolers-screening


-------------------


Ancient Wolf Genome Reveals an Early Divergence of Domestic Dog Ancestors and Admixture into High-Latitude Breeds

http://genetics.med.harvard.edu/reichlab/Reich_Lab/Welcome_files/Pontus_TaimyrWolf_CurrentBiology_2015.pdf


----------------------


Origin of the domestic dog

https://en.wikipedia.org/wiki/Origin_of_the_domestic_dog

{What would happen if you kept breeding these Pug dogs with these facial deformities, do you think that Pugs could turn into an even more dysgenic type of breed}.


-----------------------


{Look at how the face of a Chow Dog is similar to that of an Oriental person.
We can see that both the Chow species of dog and Orientals have lived in the same
area where these face deformities have occurred. Some Orientals however are also very good at breathing at high altitudes, such as the people of Tibet. We can see that the reason why Orientals can breathe at higher altitudes is they have more Denisovan animal DNA.

 More research needs to be done to see how a deformity in an airway of the nose can cause different genetic mutations in brachycephalic species of dogs, and including brachycephalic species of humans}.


-----------

Things to think about before buying a flat-faced (brachycephalic) dog


https://www.bluecross.org.uk/pet-advice/things-think-about-buying-flat-faced-dog

{Wow look at this, we even see similar eye problems in flat faced dogs and brachycephalic dogs
as we see in black people}.

-----------------

Gene which helps people cope with low oxygen levels at high altitudes could become target for new drugs to treat heart disease


https://www.aao.org/eye-health/news/ethnicity-eye-disease-risk-reminder-asian-african-


--------------



 Vision risks vary by ethnic and genetic backgrounds

 https://versanthealth.com/visionreferencelibrary/2017/04/24/risk-of-vision-problems-increased-in-certain-ethnic-groups/



Vision problems can affect all of us, with age and gender being just two factors. Did you know that different ethnicities can also play an important role? Research suggests that some ethnic backgrounds are subject to an increased risk of vision problems compared to others.

African Americans


Cataracts

African Americans are more likely than Caucasians to develop cataracts. As a result, they are five times more likely to develop blindness.

Glaucoma
African Americans are also five times more likely than Caucasians to develop glaucoma, and four times more likely to suffer blindness from it as a result. Glaucoma is often characterized by the loss of periphery vision that can progress to complete vision loss without treatment.


Asian Americans

Asian Americans are more likely than the national average to develop angle-closure glaucoma…

Glaucoma

Asian Americans are more likely than the national average to develop angle-closure glaucoma, caused by rapid or sudden increases in pressure inside the eye. Glaucoma is often characterized by the loss of periphery vision that can progress to complete vision loss without treatment. People of Japanese descent are also more prone to a particular type of the disease, called low-tension glaucoma.

Caucasians


While cataracts are more common among African Americans and Hispanics, Caucasians are also at risk. Extended exposure to UV rays from the sun is a risk factor.

Hispanics


Cataracts
Among Hispanics, cataracts are three times more common vs. Caucasians and African Americans. The disease is the leading cause of visual impairment among Hispanic adults. Extended exposure to UV rays is a risk factor.



---------------


{Orientals and the eyes of black people are more deformed, this is why they have more eye problems. Blacks have a smaller skull on average, and black people also have more eye problems than other races}.

---------------

Glaucoma in the African American and Hispanic Communities

https://www.brightfocus.org/glaucoma/article/glaucoma-african-american-and-hispanic-communities

----------------


African Americans and Glaucoma


https://www.glaucoma.org/glaucoma/african-americans-and-glaucoma.php


-----------------


How Popular Dog Breeds Have Changed Over Time

https://brightside.me/wonder-animals/how-popular-dog-breeds-have-changed-over-time-649110/

{Look at how the Pug dog actually became a dysgenic race of dog.
Many say that different races of humans had a similar fate as the Pug.
Many say that blacks are not the original humans, and that whites are the original humans.
Look at what happens when a group of species becomes dysgenic in a dog species, many think
that this is a form of dysgenic devolution. Many think that certain dysgenic mutations would have a similar effect in humans.

The Pug is a brachycephalic breed and their traits have become exaggerated. As a result, they have heart and breathing problems, high blood pressure, and low blood oxygen levels.

We can clearly see that the results for the Pug dog is similar to dysgenic traits in black humans. Both Pugs and black people have additional heart and breathing problems, including high blood pressure}.


----------------------


More oxygen in eyes of African-Americans may help explain glaucoma risk

http://www.isionaware.org/blog/visionaware-blog/african-american-patients-highest-risk-for-diabetic-retinopathy-and-lowest-rates-for-follow-up-eye-care-%E2%80%93-what-kind-of-education-is-needed/12

They found that oxygen levels are significantly higher in the eyes of African-Americans with glaucoma than in Caucasians with the disease. The researchers report their findings in the July issue of the Archives of Ophthalmology. They suspect that more oxygen may damage the drainage system in the eye, resulting in elevated pressure. Higher pressure can damage the optic nerve, causing blindness.

The study provides the first physiologic clue about the link between race and risk for glaucoma. Glaucoma is the leading cause of blindness among African-Americans. Compared to Caucasians, glaucoma is about six times more common in African-Americans, and blindness caused by glaucoma is roughly 16 times more likely in African-Americans.


-------------------



Why 7 Deadly Diseases Strike Blacks Most


    Diabetes is 60% more common in black Americans than in white Americans. Blacks are up to 2.5 times more likely to suffer a limb amputation and up to 5.6 times more likely to suffer kidney disease than other people with diabetes.
    African-Americans are three times more likely to die of asthma than white Americans.
    Deaths from lung scarring -- sarcoidosis -- are 16 times more common among blacks than among whites. The disease recently killed former NFL star Reggie White at age 43.
    Despite lower tobacco exposure, black men are 50% more likely than white men to get lung cancer.
    Strokes kill 4 times more 35- to 54-year-old black Americans than white Americans. Blacks have nearly twice the first-time stroke risk of whites.
    Blacks develop high blood pressure earlier in life -- and with much higher blood pressure levels -- than whites. Nearly 42% of black men and more than 45% of black women aged 20 and older have high blood pressure.
    Cancer treatment is equally successful for all races. Yet black men have a 40% higher cancer death rate than white men. African-American women have a 20% higher cancer death rate than white women.

Why?

Genes definitely play a role. So does the environment in which people live, socioeconomic status -- and, yes, racism, says Clyde W. Yancy, MD, associate dean of clinical affairs and medical director for heart failure/transplantation at the University of Texas Southwestern Medical Center.

https://www.webmd.com/hypertension-high-blood-pressure/features/why-7-deadly-diseases-strike-blacks-most#1



---------------------


Asthma Studies Raise Thorny Questions about Race and Genetics

 Research shows that African-Americans don’t respond as well as their white counterparts to some of the most common asthma controller medications, raising questions about how those medications are tested in clinical trials.

 http://www.calhealthreport.org/2017/05/01/asthma-studies-raise-thorny-questions-about-race-and-genetics/


---------------------


 Genetic Ancestry Is Associated With Measures of Subclinical Atherosclerosis in African Americans


Conclusions—

Overall, our findings indicate that genetic ancestry was associated with subclinical atherosclerosis, suggesting unmeasured risk factors and interactions with genetic factors might contribute to the distribution of subclinical atherosclerosis among African Americans.

https://www.ahajournals.org/doi/10.1161/ATVBAHA.114.304855


-----------------------

HPV Vaccines May Be Less Effective in African American Women

African American women are more likely to have HPV strains that are not included in current vaccines.

https://www.everydayhealth.com/womens-health/hpv-vaccines-may-be-less-effective-in-african-american-women-researchers-find.aspx


-------------------------


CDC: Genital Herpes Among Black Women High


 https://www.npr.org/templates/story/story.php?storyId=124628530



-----------------------

 

Interracial Marriage More Common Than Ever, but Black Women Still Lag

https://abcnews.go.com/WN/Media/black-women-marry-interracial-marriage-common/story?id=10830719


----------------------

Breast Cancer in Young African American Women

 https://www.cdc.gov/healthcommunication/toolstemplates/entertainmented/tips/BreastCancerAfricanAmerican.html

Resources for Entertainment Education Content Developers.


What’s the Problem?

Every year, 24,000 women under the age of 45 are diagnosed with breast cancer; and 3,000 will die as a result. Young African American women under the age of 35 have breast cancer rates that are two times higher than Caucasian women of the same age. Furthermore, young African American women are three times as likely to die from breast cancer as Caucasian women of the same age. Once diagnosed, young African American women face unique challenges that are either not present or are less severe for older women. Having a breast health course of action and discussing the significant implications of a breast cancer diagnosis is essential for young African American women in taking care of their health.


--------------------


Eye Diseases Among African Americans

The most common eye diseases and conditions that affect African Americans include cataract, diabetic eye disease, glaucoma, and low vision. Many of these diseases and conditions do not have noticeable symptoms in their early stages, but they can be detected through a comprehensive dilated eye exam. Treatment is most effective when an eye disease is diagnosed early.

https://nei.nih.gov/nehep/programs/write-the-vision/eye-diseases-among-african-americans


----------------------


African Americans at Increased Risk for Eye Diseases

https://yoursightmatters.com/african-americr-eye-diseases/


-----------------------

Immune system of African-Americans responds more strongly to bacterial infection

This immune system response is partly genetic!


 While the immune system of African Americans responds more strongly, Professor Barreiro is careful to qualify it as better: "The immune system of African Americans responds differently, but we cannot conclude that it is better, since a stronger immune response also has negative effects, including greater susceptibility to autoimmune inflammatory diseases such as Crohn's disease. Too much inflammation can damage organs and leave sequelae. In short, a strong immune response can be beneficial in some areas but a disadvantage in others.

 https://www.eurekalert.org/pub_releases/2016-10/uom-iso101716.php


---------------------------


Racial Classification of Indian People (by Different Anthropologist)

http://www.yourarticlelibrary.com/essay/anthropology/racial-classification-of-indian-people-by-different-anthropologist/41839


------------------------

 Inbreeding depression and intelligence quotient among north Indian children.

1993

https://www.ncbi.nlm.nih.gov/pubmed/8240214

------------------------








-------------------------


Who were the ghost people of Africa? DNA reveals ancient Africans bred with new unknown race of humans just 50,000 years ago

 13 February 2020

    The researchers studied the genetic material of 405 people from West Africa
    They discovered mystery genetic material, which they have termed 'ghost DNA'
    It suggests that humans mixed with an unknown group about 50,000 years ago


https://www.dailymail.co.uk/sciencetech/article-7997861/New-study-shows-ghost-DNA-modern-day-population-west-Africa.html


-------------------------





FACTSHEET: Africa’s leading causes of death

https://africacheck.org/factsheets/factsheet-africas-leading-causes-death/



Africa’s top 5 causes of death

 
#1  Lower respiratory tract infections

The leading cause of death in Africa, lower respiratory tract infections target your airways and lungs. Diverse in origin, they stem from many viruses and bacteria and occasionally fungi or parasites.

The most common illnesses are bronchitis or pneumonia. Pneumonia is single-handedly responsible for 16% of global deaths of children younger than five, with a significantly greater share in Africa.

The notable exclusion from this category is tuberculosis as the disease can infect virtually anywhere in the body even if initially limited to the lungs.



---------------------------------



What You Should Know About Sickle Cell Trait

https://www.cdc.gov/ncbddd/sicklecell/documents/SCD%20factsheet_Sickle%20Cell%20Trait.pdf


In their extreme form and in rare cases, the following conditions could be harmful for people with
SCT:Increased pressure in the atmosphere (e.g., while scuba diving).
•Low oxygen levels in the air
 (e.g., when mountain climbing,
•exercising extremely hard in military boot camp, or training for
an athletic competition).Dehydration (e.g., too little water in the body).
•High altitudes
(e.g., flying, mountain climbing, or visiting a city at
•a high altitude).



----------------------------------



{After reading the problem with genetics in blacks and in Pug dogs, many people have changed their opinion on the theory that blacks were the first humans with all of these dysgenic traits.

We can see the species of Pug has actually now regressed, this same type of devolution happens
in humans as well. We can see how many African bushmen have an IQ average of around 70 in some places, when we have white people with an IQ of over 120 inventing nuclear weapons and new types of lazers.

Could it be possible for a dysgenic species of Pug to breed with another species of dog to try and
revitalize its species and become a new hybrid breed of dog}.


--------------------------


 Brachycephalic airway obstructive syndrome


https://en.wikipedia.org/wiki/Brachycephalic_airway_obstructive_syndrome

 

------------------------


{Some blacks even look like dogs, some blacks even look like a Pit Bull or Doberman}.


-------------------------

Snoop Dogg turns into a dog 

SNOOP DOGG - WHO AM I (WHATS MY NAME)

https://www.youtube.com/watch?v=-hIjgofcuWU


---------------------------


A Dog's Size and Head Shape Predicts Its Behavior

The shape and size of a dog seems to be associated with its temperament.

 https://www.psychologytoday.com/us/blog/canine-corner/201603/dogs-size-and-head-shape-predicts-its-behavior

Our selective breeding of dogs has modified their size and their shape dramatically so that the more than 400 recorded breeds of dogs are easily recognizable based on their physical characteristics. It also appears that there is some correlation between a dog's head shape and the functions that they perform for humans; for example the sighthounds (who pursue game over open ground) tend to have long narrow heads, while many of the guarding breeds tend to have more square shaped heads.

A team of researchers headed by Holly Stone of the Faculty of Veterinary Science at the University of Sydney in Australia decided to see if the body size and head shape of dogs predicted aspects of canine behavior. Their report appears in the journal PLoS ONE. This is a massive study, involving 67,368 dogs from 45 different breeds. Data collection was done over a period of eight years at 235 testing areas in Sweden. The behavior testing was done using the Dog Mentality Assessment Test, which is a standardized behavioral test involving 10 different subtests designed to measure a dog's aggressiveness, defensiveness, playfulness and sociability, fearfulness, chase instinct, curiosity and so forth. Some of the subtests involve observing the dog's reactions to individuals who appear to be strange or threatening, other measures test their reactions to sudden events like strange sounds, gunshots, or dummies that pop up from nowhere.

The physical variables that the researchers were interested in were primarily the height and weight of the dog, and the shape of the dog's head. While the first two variables are obvious the shape of the dog's head requires a bit of explanation. There is a lot of variability in head shape among the various dog breeds. Put simply, head shape ranges from the long-headed dogs, technically called "dolichocephalic" (such as the Afghan Hound or the Greyhound) to the broader wide-skulled dogs technically called "brachycephalic" (such as the Pug or French Bulldog). In between are the "mesocephalic" (sometimes called "mesaticephalic") which would include the Golden Retriever or the Beagle. You can see some examples below.

The dog's height predicted a number of aspects of the dog's behavioral tendencies. It may be a surprise to many people to find that shorter dogs were found to be generally more aggressive than taller dogs. In addition the taller dogs tended to show more affection, cooperation, and playfulness with humans.

The dog's weight also predicted certain personality characteristics. Heavier dogs tended to be bolder, more inquisitive, and attentive. Lighter dogs tended to be more cautious and fearful.

Head shape also predicted some differences in temperament. The brachycephalic dogs seem to be more engaged with their owners with a higher interest in human-directed play. On the other hand these short-faced dogs were more defensive when faced with a difficult to interpret situation (such as seeing a person dressed like a ghost). The dolichocephalic dogs seem to be less likely to engage in object play, especially with unfamiliar humans. However these long-faced dogs were not as easily startled and recovered more quickly when an unexpected event occurred.

These are just the major findings. However the overall conclusion is that the height, weight, and head shape of dogs can predict certain important behavioral and temperament variables including certain aspects of aggression, fearfulness, sociability and affection. In general it supports Sigmund Freud's contention that "Physiology is destiny," at least when it comes to the size and shape of dogs.

For those of you who are curious (perhaps to check the head shape of your own dog) I have included a brief list of dog breeds classified by their head shape below:


List of dolichocephalic (long-headed) dog breeds

        Afghan Hound
        Airedale Terrier
        Basset Hound
        Bedlington Terrier
        Bloodhound
        Borzoi
        Bull Terrier
        Cesky Terrier
        Dachshund
        Doberman Pinscher
        English Bull Terrier
        German Shepherd
        Great Dane
        Greyhound
        Ibizan Hound
        Irish Wolfhound
        Italian Greyhound
        Manchester Terrier
        Miniature Bull Terrier
        Pharaoh Hound
        Poodle
        Rough Collie
        Saluki
        Scottish Deerhound
        Scottish Terrier
        Shetland Sheepdog
        Smooth Fox Terrier
        Whippet
        Wire Fox Terrier

List of mesocephalic (medium-headed) dog breeds

        Alaskan Malamute
        American Cocker Spaniel
        Australian Cattle Dog
        Australian Shepherd
        Basenji
        Beagle
        Bearded Collie
        Beauceron
        Belgian Malinois
        Belgian Sheepdog
        Bernese Mountain Dog
        Bichon FrisĂ©
        Black and Tan Coonhound
        Border Collie
        Border Terrier
        Brittany Spaniel
        Cairn Terrier
        Cardigan Welsh Corgi
        Chesapeake Bay Retriever
        Chinese Crested
        Clumber Spaniel
        Dalmatian
        English Cocker Spaniel
        English Foxhound
        English Springer Spaniel
        Field Spaniel
        German Shorthaired Pointer
        Golden Retriever
        Irish Setter
        Japanese Spitz
        Keeshond
        Komondor
        Kuvasz
        Labrador Retriever
        Maltese
        Miniature Pinscher
        Norfolk Terrier
        Norwich Terrier
        Papillon
        Pembroke Welsh Corgi
        Pomeranian
        Rottweiler
        Saint Bernard
        Samoyed
        Siberian Husky
        Vizsla
        Weimaraner
        West Highland White Terrier
        Yorkshire Terrier

List of brachycephalic (short-headed) dog breeds

        Affenpinscher
        American Pit Bull Terrier
        American Staffordshire Terrier
        Boston Terrier
        Boxer-
        Brussels Griffon
        Bulldog
        Bullmastiff
        Cavalier King Charles Spaniel
        Chow Chow
        Dogo Argentino
        Dogue de Bordeaux
        English Mastiff
        French Bulldog
        Japanese Chin
        King Charles Spaniel (or English Toy Spaniel)
        Lhasa Apso
        Neapolitan Mastiff
        Newfoundland
        Pekingese
        Pug
        Shar-Pei
        Silky Terrier
        Tibetan Spaniel
        Yorkshire Terrier.



-----------------------------------------------


{We can see that the Pug is classified as the same head type of brachycephalic (short-headed) dog breeds as a Pit Bull and Chow Chow, two of the some of the most unpredictive dogs known to attack humans. It seems that each head type of dog has its own different aggressive dogs
as well. Maybe this is sometimes why some races act more aggressive than others, and why
some third world nations continue to be in the state of decay that they are in}.


----------------


Variation of BMP3 Contributes to Dog Breed Skull Diversity

https://www.research.ed.ac.uk/portal/files/9919170/Variation_of_BMP3_Contributes_to_Dog_Breed_Skull_Diversity.pdf


----------------------


Impact of Facial Conformation on Canine Health: Brachycephalic Obstructive Airway Syndrome

Abstract

The domestic dog may be the most morphologically diverse terrestrial mammalian species known to man; pedigree dogs are artificially selected for extreme aesthetics dictated by formal Breed Standards, and breed-related disorders linked to conformation are ubiquitous and diverse. Brachycephaly–foreshortening of the facial skeleton–is a discrete mutation that has been selected for in many popular dog breeds e.g. the Bulldog, Pug, and French Bulldog. A chronic, debilitating respiratory syndrome, whereby soft tissue blocks the airways, predominantly affects dogs with this conformation, and thus is labelled Brachycephalic Obstructive Airway Syndrome (BOAS). Despite the name of the syndrome, scientific evidence quantitatively linking brachycephaly with BOAS is lacking, but it could aid efforts to select for healthier conformations. Here we show, in  an exploratory study of 700 dogs of diverse breeds and conformations, and a confirmatory study of 154 brachycephalic dogs, that BOAS risk increases sharply in a non-linear manner as relative muzzle length shortens. BOAS only occurred in dogs whose muzzles comprised less than half their cranial lengths. Thicker neck girths also increased BOAS risk in both populations: a risk factor for human sleep apnoea and not previously realised in dogs; and obesity was found to further increase BOAS risk. This study provides evidence that breeding for brachycephaly leads to an increased risk of BOAS in dogs, with risk increasing as the morphology becomes more exaggerated. As such, dog breeders and buyers should be aware of this risk when selecting dogs, and breeding organisations should actively discourage exaggeration of this high-risk conformation in breed standards and the show ring.


https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137496


----------------------


Brachycephalic Feline Noses

Ct and anatomical study of the relationship between head conformation and the nasolacrimal drainage system

https://journals.sagepub.com/doi/pdf/10.1016/j.jfms.2009.09.010


-------------------------


 Flat-Faced Cats Are Even Weirder Than They Look

"If you are a light sleeper, they do tend to snore."


https://www.thedodo.com/close-to-home/flat-faced-cat-breed-health-problems


 -----------------------------------------------------


Convergence and Divergence in the Evolution of Cat Skulls: Temporal and Spatial Patterns of Morphological Diversity

July 6, 2012

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039752


-----------------------------------------------------



Evolution of Skull and Mandible Shape in Cats (Carnivora: Felidae)

2008

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475670/


-----------------------------------------------------


Functional Morphology and the Evolution of Cats

1980

https://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1286&context=tnas


-----------------------------------------------------


Skulls shed new light on the evolution of the cat

July 10, 2012

https://phys.org/news/2012-07-skulls-evolution-cat.html


-----------------------------------------------------



This Fossil Skull Unearthed in Tibet Is the Oldest Big Cat Ever Found

November 12, 2013

The fossil belongs to a newly discovered species called Panthera blytheae and is between four and five million years old

https://www.smithsonianmag.com/science-nature/this-fossil-skull-unearthed-in-tibet-is-the-oldest-big-cat-ever-found-180947677/


-----------------------------------------------------


CAT scans of sabertooth cats’ skulls unearth evolution of predatory behavior

 October 31, 2018

https://dailybruin.com/2018/10/31/researches-uncover-sabertooth-tiger-bites-hard/


-----------------------------------------------------



Long in the Tooth: Evolution of Sabertooth Cat Cranial Shape

2008

https://www.jstor.org/stable/20445602?seq=1


-----------------------------------------------------


Fossils reveal saber-toothed cats may have pierced rivals’ skulls

May 31, 2019

https://www.sciencenews.org/article/fossils-reveal-saber-toothed-cats-may-have-pierced-rivals-skulls


-----------------------------------------------------


A skull of Machairodus horribilis and new evidence for gigantism as a mode of mosaic evolution in machairodonts (Felidae, Carnivora)

2016

http://www.ivpp.cas.cn/cbw/gjzdwxb/xbwzxz/201608/P020161024540721718686.pdf


-----------------------------------------------------


Smithsonian scientist confirms missing link in big cat evolution

1-8-2014

https://insider.si.edu/2014/01/smithsonian-scientist-confirms-missing-link-in-big-cat-evolution/


-----------------------------------------------------


Fossil Find Clears Up Big Cat Origins

2013

https://www.nationalgeographic.com/news/2013/11/131112-big-cats-origin-tibet-animals-science/


------------------------------------------------------


Big cat, small cat: reconstructing body size evolution in living and extinct Felidae

 15 June 2015

https://onlinelibrary.wiley.com/doi/full/10.1111/jeb.12671


------------------------------------------------------

 


PALLAS CAT is the Wildest Cat in the World. PALLAS CAT - Rare, Vicious, Wild mountain CAT!

May 13, 2021

https://www.youtube.com/watch?v=ID7zchiVMqE

 

------------------------------------------------------


Morphological variation of the caudal fossa of domestic cat skulls assessed with CT and geometric morphometrics analysis

7-19-2017

https://journals.sagepub.com/doi/abs/10.1177/1098612X17730707


------------------------------------------------------


Variants in the Domestic Cat Genome: Shedding New Light on Feline Domestication

2015

https://www.vin.com/apputil/content/defaultadv1.aspx?id=6976360&pid=12513&


------------------------------------------------------


How fancy cats evolved: The science of our most adorable pets

May 25, 2015

https://www.salon.com/2015/05/25/how_fancy_cats_evolved_the_science_of_our_most_adorable_pets/


------------------------------------------------------


Here's Why Cats Have Such Strange, Haunting Eyes, Explained by Science

30 JUNE 2018

https://www.sciencealert.com/here-s-why-cats-have-such-weird-eyes


------------------------------------------------------




Wild cat brains: An evolutionary curveball

Oct. 31, 2016

https://msutoday.msu.edu/news/2016/wild-cat-brains-an-evolutionary-curveball/



------------------------------------------------------


Cuddly kitty or killer? Evolution explains why cats are grumpy

https://www.nbcnews.com/sciencemain/cuddly-kitty-or-killer-evolution-explains-why-cats-are-grumpy-8C11073589


------------------------------------------------------

 

Brachycephalic Dogs And Cats

Breeds To Watch In And Around Water – breeds to watch closely in and around water because of their propensity to breathe in the water while swimming or running around.

https://www.pve.net.au/44-brachycephalic/

{Could this be the reason why brachycephalic Africans are not very good swimmers}?


-----------------


The Genetics of Canine Skull Shape Variation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567726/


---------------


Ethnic Differences in BMI and Disease Risk

The chance of developing diabetes, heart disease, and other weight-related health risks increases with increasing body mass index (BMI). But theres strong evidence that at any given BMI, these health risks are markedly higher in some ethnic groups than others.

The Nurses Health Study, for example, tracked patterns of weight gain and diabetes development in 78,000 U.S. women, to see if there were any differences by ethnic group.  All women were healthy at the start of the study. After 20 years, researchers found that at the same BMI, Asians had more than double the risk of developing type 2 diabetes than whites; Hispanics and blacks also had higher risks of diabetes than whites, but to a lesser degree. Increases in weight over time were more harmful in Asians than in the other ethnic groups: For every 11 pounds Asians gained during adulthood, they had an 84 percent increase in their risk of type 2 diabetes; Hispanics, blacks, and whites who gained weight also had higher diabetes risks, but again, to a much lesser degree than Asians. Several other studies have found that at the same BMI, Asians have higher risks of hypertension and cardiovascular disease than their white European counterparts, and a higher risk of dying early from cardiovascular disease or any cause.

Researchers are still teasing out why Asians have higher weight-related disease risks at lower BMIs. One possible explanation is body fat. When compared to white Europeans of the same BMI, Asians have 3 to 5 percent higher total body fat. South Asians, in particular, have especially high levels of body fat and are more prone to developing abdominal obesity, which may account for their very high risk of type 2 diabetes and cardiovascular disease. In contrast, some studies have found that blacks have lower body fat and higher lean muscle mass than whites at the same BMI, and therefore, at the same BMI, may be at lower risk of obesity-related diseases. (Keep in mind, though, that in the U.S., the prevalence of obesity is higher in non-Hispanic blacks than in non-Hispanic whites, so the overall burden of obesity-related diseases is still higher in this group. Read more about obesity trends in the U.S. and other countries.)

While genetic differences may be at the root of these different body fat patterns in Asians and other ethnic groups, environmental factors seem to be a much stronger force. For example, research suggests that under-nutrition during fetal life, such as during the Chinese famine of 1954 to 1964, raises the risk of diabetes in adulthood, especially when individuals live in nutritionally rich environments later in life. (Read more about prenatal and early life influences on obesity.)

https://www.hsph.harvard.edu/obesity-prevention-source/ethnic-differences-in-bmi-and-disease-risk/


---------------------------


Ethnic differences in bone geometry between White, Black and South Asian men in the UK

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004623/


----------------------------


Is Girls’ Generation the outcome of the Pleistocene mind?

http://blogs.discovermagazine.com/gnxp/2013/02/is-girls-generation-the-outcome-of-the-pleistocene-mind/#.XF5nHrh7mcw

There’s an excellent paper up at Cell right now, Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant. It synthesizes genomics, computational modeling, as well as the effective execution of mouse models to explore non-pathological phenotypic variation in humans. It was likely due the last element that this paper, which pushes the boundary on human evolutionary genomics, found its way to Cell (and the “impact factor” of course).

The focus here is on EDAR, a locus you may have heard of before. By fiddling with the EDAR locus researchers had earlier created “Asian mice.” More specifically, mice which exhibit a set of phenotypes which are known to distinguish East Asians from other populations, specifically around hair form and skin gland development. More generally EDAR is implicated in development of ectodermal tissues. That’s a very broad purview, so it isn’t surprising that modifying this locus results in a host of phenotypic changes. The figure above illustrates the modern distribution of the mutation which is found in East Asians in HGDP populations.

One thing to note is that the derived East Asian form of EDAR is found in Amerindian populations which certainly diverged from East Asians > 10,000 years before the present (more likely 15-20,000 years before the present). The two populations in West Eurasia where you find the derived East Asian EDAR variant are Hazaras and Uyghurs, both likely the products of recent admixture between East and West Eurasian populations. In Melanesia the EDAR frequency is correlated with Austronesian admixture. Not on the map, but also known, is that the Munda (Austro-Asiatic) tribal populations of South Asia also have low, but non-trivial, frequencies of East Asian EDAR. In this they are exceptional among South Asian groups without recent East Asian admixture. This lends credence to the idea that the Munda are descendants in part of Austro-Asiatic peoples intrusive from Southeast Asia, where most Austro-Asiatic languages are present.

And yet one thing that jumps out at me is that there is no East Asian EDAR in European populations, even in Russians. I am a bit confused by this result, because of the possibility of Siberian-affiliated population admixture with Europeans within the last 10,000 years, as adduced by several researchers (this is not an obscure result, it manifests in TreeMix repeatedly). The second figure shows the inferred region from which the East Asian EDAR haplotype expanded over the past 30,000 years. The authors utilized millions of forward simulations with a host of parameters to model the expansion of EDAR, so that it fit the distribution pattern that is realized (see the supplements here for the parmeters). To make a long story short they infer that there was one mutation on the order of ~30,000 years before the present, and that it swept up in frequency driven by selection coefficients on the order of ~0.10 (10% increase relative fitness, which is incredibly powerful!). This is on the extreme end of selective sweeps, and likely of the same class as the haplotype blocks which characterize SLC24A5 and LCT (the block is shorter, though that makes sense because of the deeper time depth). Again, I am perplexed why such an ancient allele, which is found in Amerindians, or Munda populations, is absent in Europeans who have putative East Eurasian admixture. The whole does not cohere for me. There is a weak point in one or more of my assumptions.

Then there’s the section on the mouse model. To me this aspect was ingenious, though I’m not particularly able to assess it on its technicalities. The earlier usage of mouse models to test the effects of mutations on EDAR was in the context of coarse copy number changes which resulted in massive dosage changes of protein. The phenotypic outcomes were rather extreme in that case. Here they used a “knockin” model where they recreated the specific EDAR point mutation. Instead of extreme phenotypes they found that the mice were much more normal in their range of traits, though the hair form shifts were well aligned with what occurred in humans. Additionally there were some changes in the number of eccrine glands, with a larger number in the derived East Asian EDAR carriers (with additive effect). Finally they noticed that there were differences in mammary gland pad area and branching. None of this is that surprising, EDAR is a significant regulatory gene which shapes the peripheries and exterior of an organism.

To double check the human relevance of what they found in the mouse model they performed a genome-wide association in a large cohort of Han Chinese. The correlations of particular traits were in the directions that they expected; those individuals with East Asian EDAR variants had thicker hair, shovel-shaped incisors, and a greater density of eccrine glands. It is perhaps important to note that the frequency of the derived variant is so high in Han populations that they didn’t have enough homozygote ancestral genotypes to perform statistics, so their comparisons involved heterozygotes with the derived mutant and also a copy of the ancestral state. This is like SLC24A5 in Europeans, where it is difficult to find individuals of European heritage who have double copies of the non-European modal variant.

Let’s review all the awesome things they did in this study. They dug deeply into the evolutionary genomics of the region around the EDAR, concluding that this haplotype was driven up in frequency from on ancestral variant ~30,000 years ago in a hard selective sweep. And a sweep of notable strength in terms of selection coefficient. This may be one of the largest effect targets of natural selection in the genome of non-Africans over the past 50,000 years. Second, they used a humanized mouse model to explore the range of phenotypes correlated with this mutational change in East Asians. So you have a strong selection coefficient on a locus, and, a range of traits associated with changes on that locus. Third, they confirmed the correlation between the traits and the mutation in humans, despite there being prior research in this area (i.e., they reproduced). This is all great science, and shows the power of collaboration between the groups.

Much of the elegance and power of the paper applies to the discussion section as well, but to be frank this is where things start falling apart for me. You can get a sense of it in The New York Times piece, East Asian Physical Traits Linked to 35,000-Year-Old Mutation. The headline here points to a legitimately important inference from this line of research, many salient physical characteristics of the human races seem to be due to strong selection events at a few loci. In addition to EDAR I’m thinking of the pigmentation loci, such as SLC24A5. I wouldn’t be surprised if there was something similar for the epicanthic fold. If it is visible, and defines between populations differences, it is generally not genomically trivial. There’s usually a story underneath that difference.

In the broad scale of human natural history the problem that arises for me is that we have traits, we have genes under selection, but we have very weak stories to explain the mechanism and context of natural selection. Here there is a strong contrast with the loci around lactase persistence and malaria resistance. In those situations the causal mechanism for the selection seems relatively clear. Critics of evolutionary psychology are wont to accuse the field of ‘Just So’ storytelling, but the same problem crops up in the more intellectually insulated domain of evolutionary genomics (in part because the field is very new, and also mathematically and computationally abstruse). To illustrate what I’m talking about I’m going to quote from the discussion of the above paper:

    A high density of eccrine glands is a key hominin adaptation that enables efficient evapo-traspiration during vigorous activities such as long-distance walking and running (Carrier et al., 1984; Bramble and Lieberman, 2004). An increased density of eccrine glands in 370A carriers might have been advantageous for East Asian hunter-gatherers during warm and humid seasons, which hinder evapo-transpiration.

    Geological records indicate that China was relatively warm and humid between 40,000 and 32,000 years ago, but between32,000 and 15,000 years ago the climate became cooler and drier before warming again at the onset of the Holocene (Wang et al., 2001; Yuan et al., 2004). Throughout this time period, however, China may have remained relatively humid due to varying contribution from summer and winter monsoons.

    High humidity, especially in the summers, may have provided a seasonally selective advantage for individuals better able to functionally activate more eccrine glands and thus sweat more effectively (Kuno, 1956). To explore this hypothesis, greater precision on when and where the allele was under selection—perhaps using ancient DNA sources—in conjunction with more detailed archaeological and climatic data are needed.

A climate adaptation is always a good bet. The problem I have with this hypothesis is that modern day gradients in the distribution of this allele are exactly the reverse of what one might expect in terms of adaptation to heat and humidity. Additionally, is there no cost to this adaptation? After the initial sweep upward, the populations where the derived EDAR mutant is found in high frequencies went through the incredible cold of the Last Glacial Maximum, and groups like the Yakuts are known to have cold adaptations today. Not only that, but the Amerindians from the arctic to the tropics all exhibit a cold adapted body morphology, the historical consequence of the long sojourn in Berengia.

Granted, the authors are not so simplistic, and the somewhat disjointed discussion alludes to the fact that EDAR has numerous phenotypic effects, and it may be subject to diverse positive selection pressures. This seems plausible on the surface, but this complexity of mechanism seems ill-fitted to the fact that the signal of selection around this locus is so clean and crisp. It seems that this is not going to be an easy story to unpack, and there’s a good deal of implicit acknowledgement of that fact in this paper. But tacked right at the end of the main text is this whopper:

    It is worth noting that largely invisible structural changes resulting from the 370A allele that might confer functional advantage, such as increased eccrine gland number, are directly linked to visually obvious traits such as hair phenotypes and breast size. This creates conditions in which biases in mate preference could rapidly evolve and reinforce more direct competitive advantages. Consequently, the cumulative selective force acting over time on diverse traits caused by a single pleiotropic mutation could have driven the rise and spread of 370A.

A simple takeaway is that the initial climatic adaptation may have given way to a cultural/sexual selective adaptation, whereby there was a preference for “good hair” as exemplified by pre-Western East Asian canons (black and lustrous), as well as a bias toward small breasts. This aspect gets picked up in The New York Times piece of course. I’ll quote again:

    But Joshua Akey, a geneticist at the University of Washington in Seattle, said he thought the more likely cause of the gene’s spread among East Asians was sexual selection. Thick hair and small breasts are visible sexual signals which, if preferred by men, could quickly become more common as the carriers had more children. The genes underlying conspicuous traits, like blue eyes and blond hair in Europeans, have very strong signals of selection, Dr. Akey said, and the sexually visible effects of EDAR are likely to have been stronger drivers of natural selection than sweat glands.

The passage here is ambiguous because the author of the article, Nick Wade, doesn’t use quotes, and I don’t know what is Akey and what is Wade’s gloss on Akey. For example, for theoretical reasons of reproductive skew (a few men can have many children) in general sexual selection is considered to be driven most often by female preference for male phenotypes. I assume Akey knows this, so I suspect that that section is Wade’s gloss (albeit, a reasonable one given the proposition of preference for smaller breasts). The main question on my mind is how seriously prominent population geneticists such as Joshua Akey actually take sexual selection to be as a force driving variation and selection in human populations. It seems that quite often sexual selection is presented as a deus ex machina. A phenomenon which can rescue our confusion as to the origins of a particular suite of traits. But our assessment of the likelihood of sexual selection presumably has to be premised on prior expectations informed by a balance of different forces one can gauge from the literature, and here my knowledge of the current sexual selection literature is weak. Perhaps my skepticism is premised on my ignorance, and the population geneticists who proffer up this explanation are more informed as to the state of the literature.

All this brings me back to the farcical title. When this paper first made news last week I was having dinner with a friend of Japanese heritage (who spent his elementary school years in Japan). I asked him point blank, “Do you like small breasts?” His initial response was “WTF!?! Razib,” but as a mouse geneticist he understood the thrust of my question after I outlined the above results to him. From personal communication with many East Asian American males I am not convinced that there is a overwhelmingly strong preference for small breasts within this subset of the population. But the key here is American. These are individuals immersed in American culture. The norms no doubt differ in East Asia. The typical visual representation of celebrity East Asian females that we see in the American media depict individuals who are slimmer and more understated in their secondary sexual characteristics than is the norm among Western female celebrities (e.g., Gong Li, the new crop of Korean pop stars, even taking into account the plastc surgery of the latter). Part of this is no doubt the reality that the normal range of variation across the population differs, and part of it may be the nature of aesthetic preferences.

But the possibility of deep rooted psychological reasons driving sexual selection (to my knowledge there was no culture which spanned South China and Siberia) brings us back to old ideas about the Pleistocene mind. And, it brings us back to evolutionary psychology, a field which is the whipping boy of both skeptics of the utility of evolutionary science in understanding human nature, and rigorous practitioners of evolutionary biology. And yet here it is not the evolutionary psychologists, but rock-ribbed statistical geneticists who I often see being quoted in the media invoking sexual selection. But do we know it is sexual selection, or is it just our best guess? Because more often than not best guesses are wrong (though best guesses are much more likely to be right than worst guesses!).

Evolutionary genomics has come a long way in the past 10 years. We know, for example, the genetic architecture and some aspects of the natural history of many traits. But, there are still shortcomings. Lactase persistence is the exception to the rule. Even a phenotype as straightforward as human pigmentation has no undisputed answer as to why it has been the repeated target of selection across Eurasia over the past 40,000 years. Oftentimes the right answer is simply that we just don’t know.


---------------------

{If you were going to say what race of humans were flat faced, you would probably
say Oriental humans.

Are Orientals the flat faced version of humans? Well yes}.

---------------------------


Obesity Is Associated With a Lower Resting Oxygen Saturation in the Ambulatory Elderly: Results From the Cardiovascular Health Study

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885157/


--------------------------


Dark skin decreases the accuracy of pulse oximeters at low oxygen saturation: the effects of oximeter probe type and gender.

https://www.ncbi.nlm.nih.gov/pubmed/18048893


-------------------------



Effects of Skin Pigmentation on Pulse Oximeter Accuracy at Low Saturation

http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1942319



-------------------------


A gene thought to be involved in helping people to cope with low levels of oxygen when they live at high altitudes could become a target for new drugs to treat heart disease at low altitude

https://www.independent.co.uk/life-style/health-and-families/health-news/gene-which-helps-people-cope-with-low-oxygen-levels-at-high-altitudes-could-become-target-for-new-10436227.html

Researchers say mice with variants of the endothelin receptor type B gene perform better than ordinary mice when subjected to low levels of oxygen


A gene thought to be involved in helping people to cope with low levels of oxygen when they live at high altitudes could become a target for new drugs to treat heart disease at low altitude, scientists have found.

Variants of the gene found in the genome of Ethiopians who live most of their lives several thousand feet above sea level are believed to play a key role in helping people overcome the problems linked with low-oxygen concentrations when living at high-altitudes.

Now researchers have found that laboratory mice with low-level variants of the endothelin receptor type B (EDNRB) gene perform better than ordinary mice when subjected to low concentrations of oxygen – which could also help to explain why East Africans tend to be good at endurance sports such as long-distance running.

“This is the first demonstration that a gene involved in high-altitude adaptation is critical in protecting cardiac function in moderate to severe hypoxia [low oxygen] at sea level,” said Gabriel Haddad of the University of California San Diego.



---------------------------

Nocturnal haemoglobin oxygen desaturation inurban and rural East African paediatric cohorts withand without sickle cell anaemia: a cross-sectionalstudy

https://adc.bmj.com/content/archdischild/early/2015/12/22/archdischild-2014-306468.full.pdf


-------------------------


{Notice how Blacks faces and noses are different than whites, and why blacks have different distinct voices than whites}.


-------------------------


Do people of different races have different voices?

https://io9.gizmodo.com/do-people-of-different-races-have-different-voices-5928125


-------------------------


Kenya introduces ambitious efforts to tackle pneumonia

https://clintonhealthaccess.org/kenya-introduces-ambitious-efforts-to-tackle-pneumonia/


------------------------


Three High-Altitude Peoples, Three Adaptations to Thin Air

Indigenous people in the Andes Mountains, Tibetan Plateau, and Ethiopian Highlands have different methods for coping with oxygen-thin air.

https://www.nationalgeographic.com/culture/2004/02/high-altitude-adaptations-evolution/


------------------------


How does altitude affect the body and why does it affect people differently?

http://theconversation.com/how-does-altitude-affect-the-body-and-why-does-it-affect-people-differently-95657


-------------------------


Curious Kids: Why do our ears pop?

http://theconversation.com/curious-kids-why-do-our-ears-pop-97259

{The air pressure of the climate a person lives in can determine their blood pressure}.



-------------------------


Low oxygen levels could drive cancer growth, research suggests

https://www.sciencedaily.com/releases/2012/05/120503194219.htm


--------------------------


What's the Connection? Your Heart Can Affect Your Breathing

https://www.nationaljewish.org/health-insights/health-infographics/whats-the-connection-your-heart-can-affect-your-breathing


--------------------------


The incredible naked mole rat can survive with hardly any oxygen

https://www.newscientist.com/article/2128428-the-incredible-naked-mole-rat-can-survive-with-hardly-any-oxygen/


--------------------------


Effects of mild lack of oxygen at birth 'long-term'

https://www.independent.ie/lifestyle/health/effects-of-mild-lack-of-oxygen-at-birth-longterm-29907475.html


-------------------------


Could a Few Extra Pounds Help You Live Longer?

https://www.scientificamerican.com/article/could-a-few-extra-pounds-help-you-live-longer/


------------------------


Central corneal thickness of Caucasians, Chinese, Hispanics, Filipinos, African Americans, and Japanese in a glaucoma clinic.

https://www.ncbi.nlm.nih.gov/pubmed/15582076


-----------------------


Atrial fibrillation among African Americans, Hispanics and Caucasians: clinical features and outcomes from the AFFIRM trial.

https://www.ncbi.nlm.nih.gov/pubmed/16573295


-----------------------


{We can clearly see that Orientals faces mutated and that the skin of Orientals is still white,
and they were in the cold climates as well. 

Were Oriental people once white skinned people who eventually had a genetic mutation in their face?

Were Oriental people a product of breeding with Denisovans? We see other theories on how if humans were related to Heidelbergensis, Graecopithecus, Australopithecus, Homo Habilis and Homo erectus as well.

In Eurasia, of course being two different continents being pushed together, you are going
to find dark skinned people and light skinned people. It is only a matter of time that
white Orientals would breed with brown skin people. Look at how many people in Indonesia and Malaysia look very brown and almost Arabic, compared to being a white Oriental from the North of Asia. Look at how Eskimo people have white skin. Many however claim that white 
people started to breed with Orientals in the northern parts of Asia, and this is why we see more white Orientals in the Northern part of Asia}.


--------------------



Comparison of vaginal shapes in Afro-American, caucasian and hispanic women as seen with vinyl polysiloxane casting.

https://www.ncbi.nlm.nih.gov/pubmed/10895030


-------------------


Racial Differences in Pelvic Anatomy by Magnetic Resonance Imaging

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593128/


---------------------


The incidence of urinary incontinence across Asian, black, and white women in the United States.

https://www.ncbi.nlm.nih.gov/pubmed/20042169


---------------------


Ethnic differences in pelvic floor muscle strength and endurance in South African women.

https://www.ncbi.nlm.nih.gov/pubmed/24464469


--------------


Asian Hair Types

https://theidleman.com/blogs/grooming/race-differences-hair-types


You might be wondering why Asian hair is so straight. Well, Asian hair grows from a round follicle which is responsible for that typically straight hair. Plus, it makes it extremely versatile when it comes to different hair styles. There are some differences in hair according to different types of Asians. Chinese hair and Oriental Asian hair is usually straight and is also the typical kind of Asian thin hair. East Asian hair, in particular, is stronger, thicker, more resistant to damages and hair loss when compared to other hair types.

Not only is Asian hair less prone to hair loss, but Asian hair growth is also remarkable. The average hair growth in a year is 15.3cm (1.3cm per month) which makes Asian hair the fastest growing type as well as the thickest hair in the world. If you're wondering why does Asian hair grow so fast, it's because it also has the longest growth cycle lasting as far as 9 years.


Race Differences in Hair Types


Asian Hair Vs Caucasian Hair

If you're wondering why Asian hair is so thick, it's because East Asian hair cuticles are much thicker and hair diameter is twice the size of Caucasian hair. Even though Asian hair types normally have fewer hair than Caucasians, the thickness of their hair shafts creates the impression of a fuller head of hair. It's also pretty rare to see a bald Asian as they experience less shedding of hair. It's also argued that for each balding Asian man there are three balding Caucasians.


Alopecia in Black Hair

Traction alopecia is the most common kind of hair loss amongst black people. That is caused by putting hair under stress through tight hairstyles such as braids and cornrows. However, black hair loss is also caused by genetic factors.

In this case, DHT is the hormone responsible for the shrinking of hair follicles and causes the hair to grow thinner and eventually leading to the closing up of hair follicles altogether. Once that happens, baldness becomes irreversible. Even though the highest number of cases of androgenetic alopecia can be found in Caucasian males, Afro hair follows suit. Another cause of hair loss is trichophyton tonsurans, a fungal hair loss type which causes localised hair loss and is most common in Afro hair.


Black Hair Breakage

As we've mentioned before, black hair is naturally more delicate and therefore it breaks more easily. However, black hair breakage can be also induced via the frequent use of relaxers and hair colourants which eventually lead to hair thinning. More importantly, this can also damage the root which leads to more permanent hair loss.
Regrow Black Hair

Unfortunately, there isn't one magic solution to hair loss. However, there are some treatments and hair growth products for black hair that can help. Natural products such as vitamins and supplements can, of course, contribute to the general health of your hair and are a fundamental part of a balanced diet. The only proven treatments for hair growth are a combination of Propecia and minoxidil which can work on all types of hair. However, it's always best to consult a professional to discuss your specific case.

If you're wondering how to make black male hair grow faster, there are no treatments that can guarantee that result or make your hair longer. It's crucial to do everything in your power to prevent your hair from breaking such as avoiding chemical relaxers and hairstyles that can cause thinning.


Caucasian Hair Types

Caucasian hair has the highest density amongst the different hair types. There are many different textures of Caucasian hair as it can be fine, straight, coarse or wavy and curly. Plus, there's an interesting range of shades from red to browns and the lightest end of the spectrum with blonde. Blondes have the greatest density with an average of 146.000 hairs on their heads followed by black hair with 110.000, brunettes with 100.000 and lastly red heads with 86.000.


--------------------


7 Reasons You're Drunker Than Your Friends
Experts weigh in on genetic, phsycial factors that affect alcohol tolerance.

https://abcnews.go.com/Health/Wellness/reasons-drunker-friends/story?id=14221338


---------------


For Asians, A Low BMI Doesn't Mean Healthy; Hypertension, Cholesterol Rates Equal To Blacks, Hispanics, And Whites

https://www.medicaldaily.com/asians-low-bmi-doesnt-mean-healthy-hypertension-cholesterol-rates-equal-blacks-hispanics-and-whites


---------------


Why Is the Obesity Rate So Low in Japan and High in the U.S.? Some Possible Economic Explanations

https://ageconsearch.umn.edu/bitstream/14321/1/tr06-02s.pdf


-------------------


Study of Alaska Natives confirms salmon-rich diet prevents diabetes, heart disease

2011

https://www.adn.com/alaska-news/article/study-alaska-natives-confirms-salmon-rich-diet-prevents-diabetes-heart-disease/2011/03/30/


--------------------


How Brain-Damaging Mercury Puts Arctic Kids at Risk

2015

Inuit children, exposed in the womb, have lower IQs because their mothers eat whale meat and other foods tainted with contaminants that drift north.

https://www.nationalgeographic.com/news/2015/03/150327-inuit-mercury-beluga-iq-canada-nunavik-arctic-faroe-islands/


---------------------------


 Mercury in Fish Linked to High Blood Pressure


2015

https://www.medicinenet.com/script/main/art.asp?articlekey=106261



----------------------------


Modern human origins: multiregional evolution of autosomes and East Asia origin of Y and mtDNA

https://www.biorxiv.org/content/10.1101/101410v5

 

---------------------------


Parasite Prevalence and the Worldwide Distribution of Cognitive Ability

https://www.researchgate.net/publication/44888621_Parasite_Prevalence_and_the_Worldwide_Distribution_of_Cognitive_Ability


-----------------------------


China is Cheating the World Student Rankings System

Enough is enough: Beijing must supply national data to assessors and not simply the results of a small minority of elite students


http://world.time.com/2013/12/04/china-is-cheating-the-world-student-rankings-system/


---------------------


Are Asians the Smartest Race?

http://www.8asians.com/2011/05/27/are-asians-the-smartest-race/

{Orientals are smart, but not as smart as a white Einstein, white Da Vinci or White Tesla, China cheats more on IQ tests}.


---------------



IQ being lowered in America

https://www.google.com/search?source=hp&ei=SN5rXLDzEMe0tQXGu5mICA&q=iq+being+lowered+in+america&btnK=Google+Search&oq=iq+being+lowered+in+america&gs_l=psy-ab.3..33i299.1454.1454..2327...0.0..0.89.163.2......0....2j1..gws-wiz.....0.ghj71vcU3hs


-----------


Average IQ by country - Race and IQ World Map

 https://ourworldindata.org/intelligence

 

-------------------

 

Minority Ethnic Pupils in the Longitudinal Study of Young People in England

Extension Report on Performance in Public Examinations at Age 16

2008

Key findings

Raw ethnic group differences in attainment at age 16

The mean score in the KS3 national tests in English, mathematics and science for Pakistani,
Bangladeshi, Black Caribbean and Black African groups were all substantially below the mean
for White British pupils, and to roughly the same extent, by the equivalent of over a whole year
of progress in terms of National Curriculum levels. At KS4, the mean score for Black
Caribbean pupils is still significantly lower than White British. However, the mean score for
Pakistani pupils is only just below the White British mean, and the mean scores for
Bangladeshi and Black African pupils do not differ significantly from the mean for White British
pupils. At KS3, Indian pupils were only marginally ahead of White British, but at KS4 they are
substantially ahead.

https://dera.ioe.ac.uk/7916/1/DCSF-RR029.pdf

 

-------------------

 

What IQ Tests Test

http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.110.9895&rep=rep1&type=pdf

 

-------------------


Does IQ Really Predict Job Performance?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557354/


---------------------


Human Development Reports

Expected years of schooling (years)

http://hdr.undp.org/en/indicators/69706



---------------


Can reading make you smarter?

https://www.theguardian.com/books/2014/jan/23/can-reading-make-you-smarter


---------------


Cal Newport on Why We'll Look Back at Our Smartphones Like Cigarettes

https://www.gq.com/story/cal-newport-digital-minimalism


---------------


{Now with the use of smartphones, we can see how cheating is even much easier}.


----------------


Poll: U.S. Teens Say Cheating Widespread

 https://abcnews.go.com/Primetime/story?id=131890&page=1


----------------


A Bi-Hemispheric and Multi-Disciplinary Approach to Human Origins

http://anthropogenesis.kinshipstudies.org/blog/2017/01/25/world-science-en-route-from-out-of-africa-to-out-of-america-first-stop-is-out-of-asia/


--------------


Natives of South America

https://en.wikipedia.org/wiki/File:NSRW_Natives_of_South_America.png


--------------


Natives of North America

https://en.wikipedia.org/wiki/File:NSRW_Natives_of_North_America.png


-----------


Asiatic Types

https://en.wikipedia.org/wiki/File:LA2-NSRW-1-0149.jpg


------------


Asian Bodies That Proudly Defy An Archetype

“You barely see Asian-American bodies in media. But when you do, you only see perfect, skinny ones.”

https://www.huffingtonpost.com/entry/asian-american-body-image_us_5aea06bfe4b06748dc8effe7


----------


Why are so many Asians so thin?

https://www.quora.com/Why-are-so-many-Asians-so-thin


-----------


10 Reasons Why Asians Are so Slim

https://brightside.me/inspiration-health/10-reasons-why-asians-are-so-slim-366160/


-------------------


The Evolution of Looks and Expectations of Asian Eyelid and Eye Appearance

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536060/


--------------------


{We can see how many Eskimos and Orientals are very white in skin color also. We can see how many Orientals get darker skin color the more south you go in East Asia. We can even see how Eskimo people would make wooden slits made for glasses to protect their eyes from the UV rays of the Sun}.


------------


Where on Earth has the highest UV?

 https://www.niwa.co.nz/sites/niwa.co.nz/files/import/attachments/Liley_2.pdf

Abstract. Ultraviolet intensities in the New Zealand summer are extreme on the international UV Index scale, but it reflects the risk of erythema, and UVI’s origin in Canada, rather than the global range. We used 7 years of TOMS v 8 estimates of surface UV to review global peak intensities, and to identify where the highest UV occurs. Throughout the Altiplano region of Peru, Bolivia, Chile and Argentina, UVI values exceed 20. The highest UVI of 25 was in the grid cell centred on Cuzco, in southern Peru (13.5° S, 3360 m a.s.l.). Peak values on the edge of the Antarctic Plateau also exceed the highest UVI in New Zealand, and are comparable to those at sea level in the tropics. The time of year for peak UV varies smoothly from spring in the Antarctic, under the annual ozone hole, through SH summer at mid-latitudes, March-April in the tropics, to NH summer in the northern extra-tropics.

A recent study showed that peak UVI values in NZ are about 40% more than at similar latitudes in North America (McKenzie et al., 2006).

 Date of peak UV 

 Finally, in Figure 4 we show the day of year on which the peak UVI values occurred. Notice that the peak UVI in Antarctica occurs in early December when the effects of the Antarctic ozone hole are still present, and from Figure 2 this peak value is significantly more that at mid-latitudes such as New Zealand. Furthermore, during the period, there are 24 hours of daylight in Antarctica, so the total daily dose can be further enhanced compared with other locations.

------------

{We can see that many giant trees grow along the latitudes of where there are many intense UV rays}.

---------------


The Wild Experiment That Showed Evolution in Real Time

By placing wild mice in large outdoor enclosures, an ambitious team of scientists has illustrated the full process of natural selection in a single study.

https://www.theatlantic.com/science/archive/2019/01/unprecedentedly-thorough-evolution-experiment/581521/

 

-----------------

 



Blepharitis

https://en.wikipedia.org/wiki/Blepharitis

 Blepharitis is one of the most common ocular conditions characterized by inflammation, scaling, reddening, and crusting of the eyelid. This condition may also cause burning, itching, or a grainy sensation when introducing foreign objects or substances to the eye. Although blepharitis is not sight-threatening, it can lead to permanent alterations of the eyelid margin. The overall etiology is a result of bacteria and inflammation from congested meibomian oil glands at the base of each eyelash. Other conditions may give rise to blepharitis, whether they be infectious or noninfectious, including, but not limited to, bacterial infections or allergies.

Causes:

Trauma   

Chemical

Radiation

Surgical

Thermal

 

 



-------------------

9 Places You Should Never Swim (Never Ever!)

https://www.youtube.com/watch?v=rhrctVyD4JI

----------------------

Was there an ancient nuclear war

 https://www.beyondsciencetv.com/2017/05/31/was-there-an-ancient-nuclear-war/

-------------------------

The Mohenjo Daro ‘Massacre’

 https://www.ancient-origins.net/ancient-places-asia/mohenjo-daro-massacre-00819

------------------------


How fancy cats evolved: The science of our most adorable pets

https://www.salon.com/2015/05/25/how_fancy_cats_evolved_the_science_of_our_most_adorable_pets/


------------


Skulls from the Past: Archaeological Negotiations of Scientific Racism

https://www.archaeologybulletin.org/articles/10.5334/bha-590/


------------


China unveils technology to create SUPER-HUMANS via hyper-muscular test-tube dogs

https://www.express.co.uk/news/world/828735/China-clone-humans-super-soldier-breed-dog-genetic-engineer

 

----------------


8. From Collaboration to Conflict: The Racial Survey of 1923-1929

https://books.openedition.org/obp/2386?lang=en


-------------


Evaluation   of   Cephalic   Indices: A   Clue   for   Racial   and   Sex   Diversity

https://pdfs.semanticscholar.org/a5a9/5e0f2f8a851e84edd991841fd3b40ae6e041.pdf


--------------


Human Differentiation

Evolution of Racial Characteristics

http://www.internetlooks.com/humandifferentiation.html


-----------------------


Why is it so hard to see an Asian American football player in NFL and college football?

https://www.quora.com/Why-is-it-so-hard-to-see-an-Asian-American-football-player-in-NFL-and-college-football


--------------------------


BMI discriminates against black people – and everyone else too


https://metro.co.uk/2018/03/30/bmi-discriminates-against-black-people-and-everyone-else-too-7421228/


-----------------



8 Health Conditions That Disproportionately Affect Black Women

https://www.self.com/story/black-women-health-conditions


-----------


Exercise Not As Beneficial For Black Girls As Whites, Study Says

https://www.huffingtonpost.com/2012/06/05/exercise-black-women-benefit-study_n_1571226.html


-------------


The Brutality Report - The Art of Glenn McCoy

My strong hunch is that political cartoonist Glenn McCoy earned his current status through quotas. As the only rabid right-winger in the New York Times' online cartoon roster, McCoy carries a special burden.

https://www.vice.com/en_au/article/yv5zvk/the-brutality-report-the-art-of-glenn-mccoy


-------------


Biggest share of whites in U.S. are Boomers, but for minority groups it’s Millennials or younger

http://www.pewresearch.org/fact-tank/2016/07/07/biggest-share-of-whites-in-u-s-are-boomers-but-for-minority-groups-its-millennials-or-younger/


---------------


Is It True That Black Don’t Crack?

https://www.refinery29.com/en-gb/ageing-different-races-wrinkles


----------------


Can Knowing Your Somatotype Help You Change Your Body Composition?

https://inbodyusa.com/blogs/inbodyblog/can-knowing-your-somatotype-help-you-change-your-body-composition/


----------------


Aging and Ageism: Cultural Influences

https://uk.sagepub.com/sites/default/files/upm-binaries/90251_Chapter_2_Pages_from_Chonody_Social_Work_Practice_With_Older_Adults.pdf


----------------



{We see that Oriental people have flat faces and small noses, while we see that Jews have
giant noses.

Here is the thing, we have Jews as some of the higher IQs and breaking some world records in
weightlifting and sports. However, many of these so-called Jews are actually biologically white.
It is sad when you see some white Jew and he honestly does not even identify as being
white, but rather being a Jew. I have seen some of the whitest Aryan people in the world
claim that they are a Jew, and that they are not white. I know the type, and they really do
think that they are a true Jew of the Bible, and are in no way connected to being biologically
white in any way or form. It just seems like it is just some white Khazarian European that converted to Judaism, and then now somehow he is no longer biologically white or European.
Many Jews have a higher percentage of Arabic DNA, and why we must keep Jews separate from a white ethno-state. Many of these so-called white Jews are not even fully white, and they are a mixed race ethno-religious group of people.

The white race is the chosen race, not these Arabic degenerates.

Some people will say that white Aryans were the true chosen people of the Bible, and these 
half Gypsy and Half Arab Jews are ruining the good name of the Biblical people while trying to usurp the title of calling themselves the chosen race.

We should deport all Jews away from white western society and Europe, and ship all Jews back to Israel. We do not want western society to inherit these brachycephalic Jewish problems and genetic diseases}.


------------ 



Eschewing the Nose Job in Image-Conscious L.A.


https://forward.com/sisterhood/322508/the-nose-job-in-la/


-----------------

Nose Jobs Are No Longer A Thing Among Teenage Jewish Girls

https://www.businessinsider.com/nose-job-numbers-shoot-down-for-jews-2012-6

-----------------



What's with Jews and their noses?

https://www.theapricity.com/forum/archive/index.php/t-65358.html


-----------------



Let's Talk about Chelsea Peretti's Nose

http://celestiaward.blogspot.com/2014/12/lets-talk-about-chelsea-perettis-nose.html


-----------------




Of Mongrels and Jews: The Deconstruction of Racialised Identities in White Supremacist Discourse

https://www.tandfonline.com/doi/pdf/10.1080/13504639752050

ABSTRACT

This research explores the construction of race and mixed race identities in a wide variety of white supremacist newsletters and periodicals published between 1969 and 1993. While traditional accounts of the white supremacist movement treat it as a movement concerned with race relations, I read this discourse as a site of the construction of race. In white supremacist discourse, interracial sexuality is defined as the ultimate abomination, and mixed race people pose a particularly strong threat. This paper explores the ways in which mixed race people, and Jews in particular, threaten the construction of a supposedly pure white racial identity. Drawing upon the insights of poststructuralism, this analysis will explore the role of boundary maintenance and the threat of border crossings in the process of constructing racial identities.



------------------


They're Not Jews. They're MAGA People. And They Run Israel

https://www.haaretz.com/opinion/.premium-they-re-not-jews-they-re-maga-people-and-they-run-israel-1.6908864


---------------



Are Jews White? It's a Mistake Even to Ask

https://prospect.org/article/are-jews-white-its-mistake-even-ask

 

---------------


What makes African Americans much more dominant in the game of Basketball

https://www.reddit.com/r/nba/comments/27htfb/what_makes_african_americans_much_more_dominant/


{Black people are not much better in football, basketball or baseball, it is that
many whites become scientists and inventors. I even honestly did not have many
problems with having blacks ever being a better athlete than me in sports. I will
say that blacks are pretty fast which makes them good in sports, white people 
often have more types of other strengths over blacks, and why you see a lot of white quarterbacks, linemen, coaches, etc.

There are a lot of biologically white American and biologically white Jewish basketball players that are as good as any black. Whites would rather become doctors and inventors to make a living, instead of playing some basketball game and not really contributing anything that great to humanity.
There are many more important things to life than football and basketball, I wish that many
of you would grow up and stop trying to worship these people playing basketball and football
that are not even that good sometimes, please stop. So what if some guy can score over 40 points
a game because he hogs the basketball, then all of you make the biggest deal out of it.

It is sad seeing all these people try to glorify a monkey throwing a basketball around, rather
than an inventor or scientists that just invented a new invention or medical cure. Shame on the
people of America, and shame on humanity for the way many of you are acting.

Blacks and Mexicans that are trying to act like these gangsters are putting the rest of humanity at risk.

If I were in power I would be thinking how I could fix the problems in many of the degenerate black and Mexican gangster communities. Honestly, we would be better off just deporting a lot of this scum to Africa.

Then you see areas that are nice all white and very nice neighborhoods, and there is no crude black or Mexican gangster trash running around trying to ruin everything.

We do not like how you just see some black or mulatto kid on the streets, and he is just starting to form into wanting to grow up acting like some black gangster rapper. Honestly the person wasn't that bad starting out, then you see them regress into the ghetto hood rat they are over the course of many years. Then before you know it, some kid who was not too bad at one point, has now evolved into a ghetto hood rat. The best thing and almost the only thing that
will save America and first world nations is to kick out the blacks and many brown Hispanics
and Arabs. If we don't kick out many of these groups, we will have the rest of the world turn into a crude African ghetto or Muslim Ghetto}.


--------------

THIRTY YEARS OF RESEARCH ON RACE DIFFERENCES IN COGNITIVE ABILITY

https://www1.udel.edu/educ/gottfredson/30years/Rushton-Jensen30years.pdf

----------------


Are Jews Smarter?

http://nymag.com/nymetro/news/culture/features/1478/

{Biologically white Jews seem to be smarter than Gypsy Jews. Many of these so-called
white skinned Jews you see running around are really just a hybrid European race}.


---------------------------------------------



The “Uniqueness” of Ashkenazi Jewish Ancestry is Important for Health

https://blog.23andme.com/ancestry/the-uniqueness-of-ashkenazi-jewish-ancestry-is-important-for-health/


------------------------------------------



"Cutting Off Your Nose to Spite Your Race": Jewish Stereotypes, Media Images, Cultural Hybridity

https://www.jstor.org/stable/42944413?seq=1#page_scan_tab_contents\


{Some Jews say they are the chosen race, yet we see how many of these Jews have giant noses and ears, and even go as far as to have plastic surgery to hide these features. Then Jews go and say how Jews are somehow the chosen race. Even when Jews have been kicked out of dozens of countries, and why many nations are aware of how Jews will try to bring down nations. We do not believe that Jews are anymore chosen than anyone else. These Jews are really no better than many types of Gypsy cultures. If anyone is the chosen race it is white people, and not these Arab looking people with Arab looking features. Of course we do not want to say that big ears and a big nose is bad, but some of these 1/3rd Arab Jews do have undesireable traits. Many people dont want that Middle Eastern giant Arabic schnoz that sticks out.  These Arabic traits are not desired traits compared to the true chosen white Aryans and white people. If I were to design humans I would try to phase out many of these degenerate Arab, African, Mexican and watered down bloodlines. We must concentrate on saving humanity and making white people the majority future race over these Arabs, blacks and Mexicans}.


------------------------------------------------

 

 Genes for nose shape found

Date:

    May 19, 2016

https://www.sciencedaily.com/releases/2016/05/160519081832.htm

 
------------------------------------------------




Do Jews Have Big Noses?!

https://www.youtube.com/watch?v=nxnPpXP3UEk

{We disagree with the following video, and that many Jews have way bigger noses than many people. Yet when you compare big nosed Jews to big nosed Italians, it can be about equal. We see what the guy in the video is trying to say, yet Jews have way larger noses than other races on average, such as Jews have way bigger noses than Orientals. African blacks many times have wider noses.

Many say that the genes that have this giant Jewish nose are also found in Arabs and some Italians, even some Irish are known for having big ears even. We would say that many Eastern Europeans also have a big nose and ear features as well. We would say that Nordic white people have smaller noses than Africans. Some say that Nordic people have smaller noses because they evolved in the cold climate, and that blacks have wider noses because they evolved in a hotter climate. The reason why Nordic humans have thinner noses than brown races is that Nordic humans are not a brown Denisovan subspecies.


It is widely up for debate if certain races of humans have been around longer than others. We appreciate the unique diversity in different features of different races, and why we promote segregation to save different races such as the white race from going extinct}.




 ---------------------------------------------------------


 A new take on the 19th-century skull collection of Samuel Morton

2018

https://www.sciencedaily.com/releases/2018/10/181004143943.htm

 

--------------------------------------------------


The Jews: a Study of Race and Environment

1911

Twelve skulls found in Basel in a cemetery dating from the thirteenth and fourteenth centuries two were dolichocephalic, while the remainder were brachycephalic, the total average being 84.6. The same variability occurs in other finds, but the skulls of most of the Sephardim—or Spanish and Portuguese Jews—are dolichocephalic.

https://www.nature.com/articles/086578a0


----------------------------------------------------


 Popular Science Monthly/Volume 55/August 1899/Are Jews Jews?


https://en.wikisource.org/wiki/Popular_Science_Monthly/Volume_55/August_1899/Are_Jews_Jews%3F


---------------------------------------------------


Is race a factor in sports success?

https://www.theguardian.com/commentisfree/2008/aug/25/race.olympics2008

{We think that success in sports has to do with training, race, genetics, nutrition and the culture that you are brought up in as well}.


--------------------------------------------------------


Ethnicity. Research shows that Caucasian and Asian women are more likely to develop osteoporosis than women of other ethnic backgrounds. Hip fractures are also twice as likely to happen in Caucasian women as in African-American women.

https://www.webmd.com/osteoporosis/guide/osteoporosis-risk-factors


---------------------------------------------------------



Ancient Man and His First Civilizations

http://realhistoryww.com/world_history/ancient/China_2.htm


{One theory to why all races can give birth to albino children is because whites were the original humans, and all other races have these white traits already built into their DNA. White people have the most variety of colors, while black people have very few colors. Do you notice how some poisonus animals have certain skin colors as a warning, this goes for the same as black people. This is a warning not to breed with blacks, including Arabs and Mexicans, and that blacks, Arabs and Mexicans mostly have become a degenerate messed off race that needs the majority of them to be sterilized in order to improve their own races, and get rid of many of the lower IQ blacks and Muslims that are a nuisance to our society. This must be done for the better part of humanity and first world civilizations to survive over many of these third world low IQ degenerates invading and ruining Europe, America and the best parts of society as we speak

Remember what I am offering for all races is to reduce the degenerate population so that the better part of blacks, brown people and white people can live without so many degenerates, and to better each race. This is so not only would a black be good at basketball, but they would also have a high IQ instead of being some low IQ degenerate that does not contribute anything to society}.




 -------------------------------------------------



Most people have pale palms which do not tan

Result of a quick look on the internet


Why do black people have white palm since all their bodies is black ?



 Best Answer - Chosen by Voters
Simple: Because the skin of the palms always has very little melanocytes (pigment producing cells) so even the darkest of people may have pale palms.
Also, it might interest you to know that from person to person the number of melanocytes doesn't vary all that much. It's just the amount of melanin that they produce which varies a lot.

https://vitamindwiki.com/Most+people+have+pale+palms+which+do+not+tan


------------------------------

Why cant you get a tan on your palms?

http://wiki.answers.com/Q/Why_cant_you_get_a_tan_on_your_palms


Skin contains the pigment melanin which is activated by exposure to light. The palms of your hands and the soles of your feet have much thicker layers of skin due to their regular contact and friction with other objects (the ground, tools, etc).
Melanocytes exist in the dermal layers of your palms and soles, but are buried beneath the more callous layers and are rarely directed at the sun. You could in theory try to tan your hands but the results would be pretty minimal compared to the rest of your body.



{We can clearly see all of the white features already built into blacks, everything from
blacks having white palms, to blacks being born as white albino people, and even being
able to have white children as well}.



-----------------------------------------------


The Genes for White Skin Didn’t Develop in Europe, UPenn Study Finds

Before this, little was known about the genetic basis for the variety in human skin tone.


Looking at genomes from different populations all over the African continent, researchers found the genetic variants responsible for skin pigmentation namely: SLC24A5, MFSD12, DDB1, TMEM138, OCA2, and HERC2. Geneticist Sarah Tishkoff was the senior author on this study. She said that in their paper, she and colleagues “show that mutations influencing light and dark skin have been around for a long time, since before the origin of modern humans.”

Our ancient ancestor Australopithecus, which lived in Eastern Africa between 3.85 and 2.95 million years ago, probably had light skin underneath dark fur. Chimps, one of our closest living relatives, are the same way. Since their fur protects them from the sun, there’s no need for more melanin. 

At some point, an ancestor of ours was born without all that tremendous body hair. It was thought that shortly after, this hominin developed dark skin to protect it against harsh UV rays. So our oldest hairless ancestor may have had white skin, but only for a brief period.

 https://bigthink.com/philip-perry/the-genes-for-white-skin-didnt-develop-in-europe-upenn-study-finds



{Theory: If we did originate from Africa, could we have originated from white skinned African beings. Now we see how everything is coming together and starting to make sense}.


----------------------------------------------


THE YELLOW MEN OF CENTRAL AFRICA

https://anthrosource.onlinelibrary.wiley.com/doi/pdf/10.1525/aa.1903.5.3.02a00080


The fact that there are large numbers of indigenes in the remote parts of the African continent whose skin is of bright copper color and whose physiognomy is quite different from that of the typical negro, is one comparatively little known to men of science, and is a source of surprise to the general public, although students of African anthropology and explorers of the interior of the continent are well aware of its occurrence. In my journeyings in the great Congo- Zambezi region I found many of these yellow people and became interested in their character and history. I have already described ' the appearance and character of my friend Ndombe, " king" of the Baschilange, who was one of the finest types of these light-colored men; but I have not yet recorded the facts connected with this phenomenon nor discussed the possible reasons for it.


--------------------------------------------


Genetic Evidence for the Convergent Evolution of Light Skin in Europeans and East Asians

 https://academic.oup.com/mbe/article/24/3/710/1240790


-------------------------------------------

Can East Asians Call Themselves 'Brown'?

 https://www.npr.org/sections/codeswitch/2017/11/16/563798938/the-gray-area-between-yellow-and-brown-skin


------------------------------------------


 New evidence suggests volcanoes caused biggest mass extinction ever

April 15, 2019

Mercury found in ancient rock around the world supports theory that eruptions caused 'Great Dying' 252 million years ago.

https://www.sciencedaily.com/releases/2019/04/190415122249.htm


------------------------------------------


66-million-year-old deathbed linked to dinosaur-killing meteor

Fossil site preserves animals killed within minutes of meteor impact

Date:
  
 March 29, 2019

https://www.sciencedaily.com/releases/2019/03/190329144223.htm


---------------------------------------



Why won’t this debate about an ancient cold snap die?

https://www.sciencenews.org/article/younger-dryas-comet-impact-cold-snap

 


-------------------------------------


Glacier Extent During the Younger Dryas and 8.2-ka Event on Baffin Island, Arctic Canada

http://science.sciencemag.org/content/337/6100/1330


-------------------------------------


 No, a Comet Didn't Destroy Advanced Civilization 12800 Years Ago 

 https://www.youtube.com/watch?v=iIuR_vKZks4

 {Some debate if this video is entirely accurate, we would like to show the video as an alternative theory.

Could a sea eruption event have caused the oceans to lose warmth and lose their currents to cause a mass extinction? Some claim that this is just another theory of what could have caused a mass extinction}.



--------------------------------------


The Intriguing Problem Of The Younger Dryas—What Does It Mean And What Caused It?

https://wattsupwiththat.com/2012/06/19/the-intriguing-problem-of-the-younger-dryaswhat-does-it-mean-and-what-caused-it/


--------------------------------------


New evidence that cosmic impact caused Younger Dryas extinctions

https://phys.org/news/2013-08-evidence-cosmic-impact-younger-dryas.html



---------------------------------------


Mormon Church Finally Says Dark Skin is Not a Sign of God’s Curse



As of Friday, Dec. 6, the Mormon Church has officially renounced the doctrine that brown skin is a punishment from God.

In the “Book of Mormon,” (not the musical but the actual sacred text) dark skin is a sign of God’s curse, while white skin is a sign of his blessing. The book tells of a conflict between two lost tribes of Israel, the Lamanites and Nephites, who journeyed to the New World and made their home in Mesoamerica. The Lamanites sinned against God, and “because of their iniquity. …the Lord God did cause a skin of blackness to come upon them” (2 Nephi 5:21). Later, when Lamanites became Christians, “their curse was taken from them, and their skin became white like unto the Nephites” (3 Nephi 2:15).

These verses were thought to explain the dark skin of Native Americans. In 1960, Church apostle Spencer W. Kimball suggested at the general conference that Native Americans who converted to Mormonism were gradually becoming lighter skinned:

https://www.alternet.org/2013/12/mormon-church-dark-skin-sign-gods-curse-no-longer/

---------------------


Banned Mormon Cartoon - EXTENDED VERSION

https://www.youtube.com/watch?v=n3BqLZ8UoZk



--------------------------------









{Mormons claim that white people we the original Adam and Eve of the Bible, and that all other
races were degenerates. This is why many say that the real chosen
people of the Bible were the white Aryans of Europe, especially around areas such as Germany. This is why we see why the Germans were so fascinated about King Arthur, the Holy Grail and the Bible.
Look at the Movie Indiana Jones and the Last Crusade, for a good example of how fascinated the Germans were with being the chosen people of the Bible. This is also why a good portion of Germany practices Christianity.

Many of the mixed race degenerate Arabic Khazarians we see now claiming to be a Jew
were not the true chosen people of the Bible. This is why many of these people who claim to
be a Jew are called the fake Khazar Gyspy Jews that are not truly the chosen people. We see that many of this fake Gypsy Arabic beggars claiming to be a Jew have usurped the name of the Biblical people and have dragged the name of the word Jew through the mud. This is like saying you are an Atlantian with very little proof.  Many of these blacks, Indians, Orientals and mixed race degenerates in the Middle East were actually the cursed races the Bible warns us about.

Look at how the white race has the best inventors and scientists through history.

Look at how much America progressed when it was a white nation, and look at how much it regressed once we let a bunch of third world degenerates into America.

This is why America now has a bunch of degenerates from Asia that have infected the rest of the world with a Third World Coronavirus.


------------------------------


The Mormons Were Correct (South Park)

https://www.youtube.com/watch?v=Pbr8IA1R5DE


---------------------------------


 Blacks: Damned by the Bible


2006


https://www.nybooks.com/articles/2006/11/16/blacks-damned-by-the-bible/


----------------------------------



Charles Barkley and the Plague of 'Unintelligent' Blacks


October 28, 2014


A history of respectability politics, from the postbellum period to today


Charles Barkley recently explained why "we as black people are never going to be successful." His reasoning is painful:


    "We as black people are never going to be successful, not because of you white people, but because of other black people. When you are black, you have to deal with so much crap in your life from other black people," Barkley said.


    Barkley, a native of Leeds, [Alabama,] said African Americans are too concerned with street cred than true success and that's holding the community back.


    "For some reason we are brainwashed to think, if you're not a thug or an idiot, you're not black enough. If you go to school, make good grades, speak intelligent, and don't break the law, you're not a good black person. It's a dirty, dark secret in the black community.


    "There are a lot of black people who are unintelligent, who don't have success. It's best to knock a successful black person down because they're intelligent, they speak well, they do well in school, and they're successful. It's just typical BS that goes on when you're black, man."


It's worth noting that there isn't much difference between Barkley's claim that "there are a lot black people who are unintelligent" and the claims of a garden-variety racist. I assume that Barkley meant to say something more nuanced. That more charitable analysis, though, is far from a "dirty dark secret." The notion that black irresponsibility is at least part of the "race problem" is widely shared among black America's most prominent figures, beginning—but not ending—with the president of the United States.


https://www.theatlantic.com/politics/archive/2014/10/charles-barkley-and-the-plague-of-unintelligent-blacks/382022/



---------------------------------




 Curse of Ham

 https://en.wikipedia.org/wiki/Curse_of_Ham



 Contents

    1 Origins
        1.1 Genesis
    2 Ham's transgression
        2.1 Seeing nakedness
        2.2 Book of Jubilees
        2.3 Medieval Judaism
    3 Curse of Canaan
        3.1 Dead Sea Scrolls
        3.2 Jubilees
        3.3 Classical Judaism
    4 Misconception, racism, and slavery
        4.1 Early Judaism and Islam
        4.2 Medieval serfdom and "Pseudo-Berossus"
        4.3 European/American slavery, seventeenth and eighteenth centuries
        4.4 Latter Day Saint movement
    5 See also
    6 References
        6.1 Citations
        6.2 Bibliography
    7 External links

The misnomer known as the Curse of Ham is more accurately known as the curse upon Canaan, Ham's son, that was imposed by the biblical patriarch Noah. The curse occurs in the Book of Genesis and concerns Noah's drunkenness and the accompanying shameful act perpetrated by his son Ham, the father of Canaan (Gen. 9:20–27). The controversies raised by this story regarding the nature of Ham's transgression, and the question of why Noah cursed Canaan when Ham had sinned, have been debated for over 2,000 years.



The story's original purpose may have been to justify the subjection of the Canaanite people to the Israelites, but in later centuries, the narrative was interpreted by some Christians, Muslims and Jews as an explanation for black skin, as well as a justification for slavery. Nevertheless, most Christians, Muslims and Jews now disagree with such interpretations, because in the biblical text, Ham himself is not cursed, and race or skin color is never mentioned.

For a period in its history the Latter Day Saint movement used the curse of Ham to prevent the ordination of black men to its priesthood.



------------------------------



The Younger Dryas Event and the Birth of the Gods | Ancient Architects

https://www.youtube.com/watch?v=nTJYmIcJk6A

{Theory: Did radiation, a comet or Sun plasma event cause one race of people or humanoids to become different races, or even different species through evolution or devolution}.



-----------------


Evidences of Nuclear Explosion in Mohenjo Daro

http://earthmysterynews.com/2016/10/19/evidences-of-nuclear-explosion-in-mohenjo-daro/


--------------------

{Some question if different types of radiation could cause different animals and species to evolve differently. Some question how humans could adapt and change physical traits in space,  this would include trying to colonize other planets with a less denser atmosphere and more intense Sun rays}.

---------------


Younger Dryas impact hypothesis

https://en.wikipedia.org/wiki/Younger_Dryas_impact_hypothesis


{Do you think that if we have had over a few different mass extinction events, that some types
of humanoid type creatures might have faced extinction or mutated? Look at how we have all different types of animals, yet we see how we have so many different colors of animals in each species.

We have brown, black, white, orange and yellow cats, rabbits, dogs, rodents, birds and many
colors of fish, snake, frogs and humans}.


-----------------------


Holocene extinction

https://en.wikipedia.org/wiki/Holocene_extinction

The Holocene extinction, otherwise referred to as the Sixth extinction or Anthropocene extinction, is the ongoing extinction event of species during the present Holocene epoch, mainly as a result of human activity. The large number of extinctions spans numerous families of plants and animals, including mammals, birds, amphibians, reptiles and arthropods. With widespread degradation of highly biodiverse habitats such as coral reefs and rainforests, as well as other areas, the vast majority of these extinctions are thought to be undocumented, as no one is even aware of the existence of the species before they go extinct, or no one has yet discovered their extinction. The current rate of extinction of species is estimated at 100 to 1,000 times higher than natural background rates.

The Holocene extinction includes the disappearance of large land animals known as megafauna, starting at the end of the last Ice Age. Megafauna outside of the African continent, which did not evolve alongside humans, proved highly sensitive to the introduction of new predation, and many died out shortly after early humans began spreading and hunting across the Earth (additionally, many African species have also gone extinct in the Holocene). These extinctions, occurring near the Pleistocene–Holocene boundary, are sometimes referred to as the Quaternary extinction event.

The arrival of humans on different continents coincides with megafaunal extinction. The most popular theory is that human overhunting of species added to existing stress conditions. Although there is debate regarding how much human predation affected their decline, certain population declines have been directly correlated with human activity, such as the extinction events of New Zealand and Hawaii. Aside from humans, climate change may have been a driving factor in the megafaunal extinctions, especially at the end of the Pleistocene.


--------------


Younger Dryas

https://en.wikipedia.org/wiki/Younger_Dryas


Brakenridge and the Vela Supernova hypothesis

Studies by Senior Research Scientist Robert Brakenridge and others suggest correlations between the Younger Dryas and a supernova that exploded within the constellation of Vela approximately around the same time, leaving behind what is now known as the Vela Supernova Remnant. Brakenridge notes other researchers that have studied effects of close-by supernovae on earth and uncovered suggestive correlating evidence during the Younger Dryas, including depletion of the ozone layer, increased UV exposure, nitrogen changes on the Earth’s surface and troposphere, evidence of global cooling, changes in 14C and 10Be in ice cores, a thin layer (approximately 30 centimeters) of “black mats”, and many extinctions that may have been caused by the explosion of the Vela Supernova.

While no cause is determined for the extinction of many species, it is suggested that a combination of some climatic change or being hunted by humans may have been a cause. Most of the species that became extinct were cold blooded species and Rancholabrean megafauna, including Mammathus Columbis, Canis Diris, and Camelops. Survivors of the Younger Dryas included that of nocturnal low-birth rate species residing in the mountainous or forest-like terrains of the Americas, Eurasia, Australia, and in Madagascar. The largest, slow breeding, diurnal species that lived in more open spaces survived in the lower parts of Africa. There were also species that went extinct that were not expected to by humans in the America, Europe, Asia, and Africa.

Across faunal and Paleoindian hunting sites, there has been evidence of carbon rich “black mats” that were approximately 30 centimeters thin, suggesting an abrupt change that occurred in a small time window and a rise in aquatic conditions. Brakenridge also discusses pollen core research that suggests global cooling conditions not to have just occurred in the Northern latitudes, but also latitudes as far as 41°south. Tree ring evidence shows a rise in 14C cosmogenic isotope. The increase may have also occurred around the same time of the increase of another cosmogenic isotope, 10Be.  Brakenridge discusses possibilities behind these rises, including climatic changes and carbon cycles or a more secular cause.

Another hypothesis that Brakenridge discusses is that effects of a supernova could have been a factor in the Younger Dryas. Effects of a supernova have been suggested before, but without confirming evidence. Brakenridge explains how with the following evidence that these effects could have been caused by a celestial event, a supernova;  observations of Gamma-ray bursts and X-ray flashes have been compared to nebular records to test this as well as supernovae flash models, comparable to the records of in-galaxy supernovae, to study the effects of such an event on Earth. These effects include depletion in the ozone later, increased UV exposure, global cooling, and nitrogen changes in the Earth’s surface and troposphere. As Brakenridge states, the only supernova possible at that time was the Vela Supernova, or classified as the Vela Supernova Remnant.



{We believe this theory to be true, and that humans faced different catastrophes as
well, it must have been difficult for this new race of darker African humans to adapt to their surroundings}.


----------------


Older Dryas

https://en.wikipedia.org/wiki/Older_Dryas


-----------------


Oldest Dryas

https://en.wikipedia.org/wiki/Oldest_Dryas


-----------------


BĂžlling oscillation

https://en.wikipedia.org/wiki/B%C3%B8lling_oscillation


-------------------


Massive Impact Crater Beneath Greenland Could Explain Ice Age Climate Swing

http://blogs.discovermagazine.com/crux/2018/11/14/greenland-crater-discovered-cause-younger-dryas/#.XFvEy7h7mcw


---------------------


The Younger Dryas termination and North Atlantic Deep Water formation: Insights from climate model simulations and Greenland ice cores

https://agupubs.onlinelibrary.wiley.com/doi/pdf/10.1029/96PA02711


---------------------


The Younger Dryas cold event in NW Himalaya based on pollen record from the Chandra Tal area in Himachal Pradesh, India

https://www.researchgate.net/publication/273382039_The_Younger_Dryas_cold_event_in_NW_Himalaya_based_on_pollen_record_from_the_Chandra_Tal_area_in_Himachal_Pradesh_India


---------------------


Arguments and evidence against a Younger Dryas impact event

https://arizona.pure.elsevier.com/en/publications/arguments-and-evidence-against-a-younger-dryas-impact-event


----------------------


A glaciological model of the Younger Dryas event in Scandinavia

https://www.cambridge.org/core/journals/journal-of-glaciology/article/glaciological-model-of-the-younger-dryas-event-in-scandinavia/D2E7A055BEF8C3C5E2A8FC83BD864291


----------------------


Platinum may point to impact theory for Younger Dryas

https://www.earthmagazine.org/article/platinum-may-point-impact-theory-younger-dryas


-------------------------


Evidence for a massive biomass burning event at the Younger Dryas Boundary

http://www.spacedaily.com/reports/Evidence_for_a_massive_biomass_burning_event_at_the_Younger_Dryas_Boundary_999.html


-----------------------


HUMAN RESPONSES TO CLIMATE CHANGE DURING THE YOUNGER DRYAS IN NORTHWEST EUROPE

https://www.repository.cam.ac.uk/handle/1810/276744


-----------------------


The Late Epipalaeolithic and Early Neolithic Occupation of the Black Desert (Jordan): Investigating the Origins of Food Production in the Marginal Zone

https://shubeika.ccrs.ku.dk/about/


--------------------------


A Blind Test of the Younger Dryas Impact Hypothesis

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0155470


----------------------


North Atlantic sea surface conditions during the Younger Dryas cold event

http://sp.lyellcollection.org/content/111/1/167


--------------------


The Younger Dryas in Equatorial and Southern Africa and in the Southeast Atlantic Ocean

http://www.dwc.knaw.nl/DL/publications/PU00011179.pdf


-------------------


Was The Younger Dryas Cooling Event Caused By A Cosmic Impact After All?

https://www.thegwpf.com/was-the-younger-dryas-cooling-event-caused-by-cosmic-impact-after-all/


--------------------


Minimal geological methane emissions during the Younger Dryas-Preboreal abrupt warming event.

https://www.ncbi.nlm.nih.gov/pubmed/28836593


--------------------


A central Texas drying event identified at the Younger Dryas-early Holocene transition using coupled speleothem ??¹³C-¹4C analysis

https://repositories.lib.utexas.edu/handle/2152/64615


--------------------


The Younger Dryas Climate Event

http://people.oregonstate.edu/~carlsand/carlson_encyclopedia_Quat_2013_YD.pdf


--------------------

Evidence for a bi-partition of the Younger Dryas Stadial in East Asia associated with inversed climate characteristics compared to Europe

https://www.nature.com/articles/srep44983


---------------------



Could a Glacial Outburst Flood Repeat the “Younger Dryas” Cooling Event?

https://iafi.org/could-a-glacial-outburst-flood-repeat-the-younger-dryas-cooling-event/


--------------------


Ancient stone carvings confirm how comet struck Earth in 10,950 BC, sparking the rise of civilisations

https://www.telegraph.co.uk/science/2017/04/21/ancient-stone-carvings-confirm-comet-struck-earth-10950bc-wiping/


---------------------




{Now we will discuss the theory on how certain species survived on Earth. It is highly debated

if humans evolved, or were in fact their own species put here by intelligent beings and then could also evolve over time. Many question if evolution is natural, or if aliens are giving assistance to creating certain animals that also have the option to evolve. One theory is that humans were put on this planet, and that many of the hominins are actually degenerates of ancient humans. An example would be such as we see in the movie Aquaman, it shows how a white race of people degenerated into a bunch of foul black subspecies of mutant type people.

This is also what many Jews and Mormons believe, is that there were an original race of people, such as a white chosen race. Then eventually other subspecies of animals such as Denisovans turned the skin of people brown, as a warning that this person was a Denisovan and not a full original human. The banned Mormon Cartoon clearly explains this, that there were cursed black races the Bible warns us about.


This is why Jews and Mormons believe that other races such as blacks are animals. However, many fake degenerative Arabic looking Jews use this ancient white religion against the original chosen white race. This is why many say that the true chosen people of the Bible were the Aryans of Germany.


We should not have Mormons try to change the original meaning of their faith, and apologize to the blacks.


King Philip II called the Filipino people inferior and we can see why. Notice how the Japanese people were actually much higher IQ than the darker brown skinned Orientals of the Philippines. This is why the religion of the Japanese is that the Japanese people were the superior race of Asia, simply because the Japanese had their own island, and were not able to breed with Filipino people who were more brown skinned and more Denisovan looking. The Filipino race is an inferior race compared to the higher IQ Asian countries. This goes to show what happens when you let a bunch of Denisovan degnerates on the same island breed for thousands of years and have a low IQ degenerative nation of brown skinned Denisovan hybrid subspecies. Japanese and Koreans also have lighter skinned Orientals than the Philippines, Indonesia and Cambodia. Japan and Korea have higher IQ than many of these countries such as the Philippines or Indonesia. This is why China, Korea or Japan would most likely be able to conquer the lower IQ countries in Asia.  If anything we should have let the higher IQ Japanese Orientals eliminate the lower IQ Filipinos. It was a huge mistake letting many of these Filipino people overpopulate and destroy the islands of the Phillipines. Now we have many unwanted Filipinos here in America that we need to remove. We are tired of seeing many overpopulated Mexicans and Filipino people that resemble a Homo floresiensis}.


----------------------------



The Philippines was named after a pasty guy from Spain who never actually set foot in the Philippines.

February 18, 2019

King Philip II, ruler of the Spanish Empire for much of the 1500s, also regarded the archipelago’s inhabitants as inferior. He’d prefer to die 100 times, he said, than become the “ruler of heretics.”

https://www.pri.org/stories/2019-02-18/duterte-s-wild-proposal-changing-name-philippines



--------------------------



{The people of the Philippines are degenerates, we should have strict population control in the Philippines and places such as Indonesia. We need to stop these Denisovan and Homo erectus subspecies from ruining more Forests and Islands in South East Asia}.



---------------------------


Duterte’s wild proposal: Changing the name of the Philippines

February 18, 2019

https://www.pri.org/stories/2019-02-18/duterte-s-wild-proposal-changing-name-philippines

 


 -------------------------



 Bats evolved diverse skull shapes due to echolocation, diet

May 2, 2019

https://www.sciencedaily.com/releases/2019/05/190502075839.htm


--------------------------------

 Signatures of echolocation and dietary ecology in the adaptive evolution of skull shape in bats

2019

https://www.nature.com/articles/s41467-019-09951-y

------------------------------------------------------


Correlation of skull morphology and bite force in a bird-eating bat

19 March 2020

https://frontiersinzoology.biomedcentral.com/articles/10.1186/s12983-020-00354-0


------------------------------------------------------


What a group of bizarre-looking bats can tell us about the evolution of mammals

14 August 2019

https://www.imperial.ac.uk/news/192467/what-group-bizarre-looking-bats-tell-about/


------------------------------------------------------


The skulls of bats were shaped by different evolutionary forces

05-02-2019

https://www.earth.com/news/skulls-bats-evolutionary-forces/


-----------------------------------------------------


Carnivorous Bats Evolved Special Skulls

https://www.iflscience.com/plants-and-animals/carnivorous-bats-evolved-special-skulls/


-----------------------------------------------------


Desert long-eared bats - snarling winged gremlins that take scorpion stings to the face and just don't care (vesper bats part VII)

March 27, 2011.

https://scienceblogs.com/tetrapodzoology/2011/03/28/desert-long-eared-bats


-----------------------------------------------------


Virus survey in populations of two subspecies of bent-winged bats (Miniopterus orianae bassanii and oceanensis) in south-eastern Australia reveals a high prevalence of diverse herpesviruses


May 24, 2018

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197625


-----------------------------------------------------


Skull specializations allow bats to feast on their fellow vertebrates

May 11, 2016

https://www.washington.edu/news/2016/05/11/skull-specializations-allow-bats-to-feast-on-their-fellow-vertebrates/



--------------------------------



Evolution and development of the cartilaginous skull: From a lancelet towards a human face

July 2019

https://www.sciencedirect.com/science/article/pii/S1084952117301453



--------------------------------



20-Million-Year-Old Skull Reveals Anthropoid Primate Brains Evolved More Than Once

 Aug 21, 2019


A fossil skull of Chilecebus carrascoensis, discovered in the Andes mountains of Chile, is the only known specimen of the species.

https://www.amnh.org/explore/news-blogs/research-posts/20-million-year-old-primate-skull




--------------------------------



This Tiny 20-Million-Year-Old Skull Could Improve Our Understanding of Brain Evolution

22 AUGUST 2019

https://www.sciencealert.com/this-tiny-ancient-skull-is-helping-us-understand-the-evolution-of-brains

 


--------------------------------



Human Evolution - Hominid Skulls

08/04/19

https://australianmuseum.net.au/learn/science/human-evolution/human-evolution-skulls/



--------------------------------


 

Larger mammals have longer faces because of size-related constraints on skull form

2013

Facial length is one of the best known examples of heterochrony. Changes in the timingof facial growth have been invoked as a mechanism for the origin of our short human facefrom our long-faced extinct relatives. Such heterochronic changes arguably permit greatevolutionary flexibility, allowing the mammalian face to be remodelled simply by modifyingpostnatal growth. Here we present new data that show that this mechanism is significantlyconstrained by adult size. Small mammals are more brachycephalic (short faced) than largeones, despite the putative independence between adult size and facial length. This patternholds across four phenotypic lineages: antelopes, fruit bats, tree squirrels and mongooses. Despite the apparent flexibility of facial heterochrony, growth of the face is linked to absolutesize and introduces what seems to be a loose but clade-wide mammalian constraint onhead shape.

https://www.nature.com/articles/ncomms3458.pdf?origin=ppub

 



--------------------------------



Skull fossil shows how whales grew to be largest animals on Earth

Tooth scratches suggest the move from toothed to filter-feeding was bridged by suction feeding. Jana Howden and Belinda Smith report.

https://cosmosmagazine.com/palaeontology/skull-fossil-shows-how-whales-became-biggest-animals-on-earth



 --------------------------------------



Toothless, 33-Million-Year-Old Whale Could Be an Evolutionary ‘Missing Link’

11/29/18

https://gizmodo.com/toothless-33-million-year-old-whale-could-be-an-evolut-1830739126



----------------------------------------------------



Prehistoric Whale Jaw Bone Sheds Light on the Evolution of Baleen

November 29, 2018

Hidden in a museums’ collections for years, a fossil provides a link between past and present feeding mechanisms

https://www.smithsonianmag.com/science-nature/prehistoric-whale-jaw-bone-sheds-light-evolution-baleen-180970917/



----------------------------------------------------


Extreme bradycardia and tachycardia in the world’s largest animal

 

 https://www.pnas.org/content/116/50/25329

 

----------------------------------------------------



 Super-Species in the calcareous plankton


https://link.springer.com/chapter/10.1007/978-3-662-06278-4_11



----------------------------------------------------



Whales evolved biosonar to chase squid into the deep

05 September 2007

https://www.berkeley.edu/news/media/releases/2007/09/05_WhaleSonar.shtml

 


--------------------------------------


Shedding new light on the evolution of the squid

February 28, 2017

https://phys.org/news/2017-02-evolution-squid.html


-----------------------------------


Brain evolution in Proboscidea (Mammalia, Afrotheria) across the Cenozoic

2019

https://www.nature.com/articles/s41598-019-45888-4


------------------------------------


Tongues, venom glands, and the changing face of Goronyosaurus

April 13, 2009.

https://scienceblogs.com/tetrapodzoology/2009/04/13/tongues-venom-goronyosaurus


---------------------------------------


The remarkable convergence of skull shape in crocodilians and toothed whales

08 March 2017

https://royalsocietypublishing.org/doi/full/10.1098/rspb.2016.2348


------------------------------------


Facing crocodiles head-on

Study examines how evolution modified the long-surviving reptiles’ snouts

February 20, 2019

https://news.harvard.edu/gazette/story/2019/02/study-examines-how-developmental-changes-modified-the-reptiles-snouts/

The story that’s often told about crocodiles is that they’re among the most perfectly adapted creatures on the planet — living fossils that have remained virtually unchanged for millions of years.

The reality is far more interesting.

Throughout their evolutionary history, crocodiles, alligators, and their kin have repeatedly evolved similar skull shapes in response to dietary specializations: long snouts for eating fish; short snouts for harder prey; and moderate snouts for large prey. But how is such broadscale convergence generated?

Research led by Stephanie Pierce, associate professor of Organismic and Evolutionary Biology, and Zachary Morris, Ph.D. ’20, aims to tackle this question by comparing embryonic development with later growth in all species of living crocodiles. Their work demonstrates that the diversity of skull shapes found today was realized by altering developmental patterns during evolution. The study is described in a Feb. 20 paper published in the Proceedings of the Royal Society B.

The work was done in collaboration with Arkhat Abzhanov at Imperial College London and Kent Vliet at the University of Florida.

“This study is just a snapshot of crocodile evolution,” Pierce said. “But it shows they have been tinkering with their developmental strategy in order to adapt to their environment, so they can be as successful as possible.”


------------------------------------


Untangling the evolution of feeding strategies in ancient crocodiles

 29 March 2019

http://www.bris.ac.uk/news/2019/march/crocodile-feeding-evolution.html


------------------------------------


Crocodiles and dolphins evolved similar skulls to catch the same prey

March 8, 2017

https://www.sciencedaily.com/releases/2017/03/170308092458.htm


------------------------------------


How evolution modified the long-surviving reptiles’ snouts

Facing crocodiles head-on.

February 21, 2019

https://www.techexplorist.com/how-evolution-modified-long-surviving-reptiles-snouts/21064/


-------------------------------------



Developmental changes resulted in changes to crocodile snouts

February 20, 2019

https://www.sciencedaily.com/releases/2019/02/190220103400.htm

 


------------------------------------



Why Crocodiles Look Like Whales

March 13, 2017

Shared dining habits have fueled a "remarkable" case of evolutionary convergence

https://blogs.scientificamerican.com/laelaps/why-crocodiles-look-like-whales/




------------------------------------


Biggest Crocodile Found—Fossil Species Ate Humans Whole?
The 27-foot predator likely ambushed our ancestors


https://www.nationalgeographic.com/news/2012/5/120508-biggest-crocodile-early-humans-science-animals/


------------------------------------




Climate change created today’s large crocodiles

September 23, 2019

https://theconversation.com/climate-change-created-todays-large-crocodiles-121933



------------------------------------




The multi-peak adaptive landscape of crocodylomorph body size evolution

07 August 2019

https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-019-1466-4



-----------------------------------



 Water pressure: Ancient aquatic crocs evolved, enlarged to avoid freezing

30-Mar-2020

Study pinpoints minimum survivable size of Jurassic crocodiles

https://eurekalert.org/pub_releases/2020-03/uon-wpa033020.php



-----------------------------------




Early Tetrapod Skull Looks like Crocodile

March 12, 2015

https://magazine.scienceconnected.org/2015/03/early-tetrapod-skull-looks-like-crocodile/



-------------------------------------



7-Million-Year-Old Fossils Show How the Giraffe Got Its Long Neck

November 25, 2015

https://www.livescience.com/52903-transitional-giraffe-fossils.html


---------------------------------------------------------


Ancient giraffe relative had thick legs, curly horns

January 13, 2016

https://phys.org/news/2016-01-ancient-giraffe-relative-thick-legs.html


---------------------------------------------------------


How the giraffe got its long neck: Nine million year old fossil sheds light on evolution of world's tallest animal

 2 NOV 2017

The giraffid, or early giraffe, is thought to have existed as far back as the early Miocene era

https://www.mirror.co.uk/science/how-giraffe-long-neck-nine-11449188


---------------------------------------------------------


Four-Horned Giraffe Ancestor Unearthed in Spain

November 2, 2017

The fossil is an unusually complete individual of an ancient giraffid species

https://www.smithsonianmag.com/smart-news/newly-discovered-specie-rewrites-giraffe-family-tree-180967059/

---------------------------------------------------------

Is this strange, three-horned extinct creature a giraffe cousin?

December 4, 2015

https://www.csmonitor.com/Science/2015/1204/Is-this-strange-three-horned-extinct-creature-a-giraffe-cousin

---------------------------------------------------------


Ontogenetic similarities between giraffe and sauropod neck osteological mobility

January 13, 2020

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227537


---------------------------------------------------------


Why sauropods had long necks; and why giraffes have short necks

2013

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628838/


---------------------------------------------------------



Newest Pterosaur Was Likely as Tall as a Giraffe

September 10, 2019

Ancient flying reptile dubbed Cryodrakon boreas, the "cold dragon of the north winds," may shed light on the evolution of these dinosaur relatives.


https://www.insidescience.org/news/newest-pterosaur-was-likely-tall-giraffe


---------------------------------------------------------


Pterosaurs Were Monsters of the Mesozoic Skies

October 1, 2019

Fossils and mathematical modeling are helping to answer long-standing questions about these bizarre animals

https://www.scientificamerican.com/article/pterosaurs-were-monsters-of-the-mesozoic-skies/


---------------------------------------------------------


 Adaptive Radiation

Students analyze characteristics of six pterosaurs to determine the role of adaptive radiation in their evolution from a common ancestor.

https://www.nationalgeographic.org/activity/adaptive-radiation/


---------------------------------------------------------



Evolutionary Transitions in the Fossil Record of Terrestrial Hoofed Mammals

16 April 2009

https://link.springer.com/article/10.1007/s12052-009-0136-1


------------------------------------


Skeletal development in the African elephant and ossification timing in placental mammals

2012

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321712/


------------------------------------


Archaeologists suggest that hominins exploited Elephant skulls for more than just their brains

29 May 2016

https://www.ucl.ac.uk/human-evolution/news/2016/may/archaeologists-suggest-hominins-exploited-elephant-skulls-more-just-their-brains


------------------------------------


Why Early Humans Were Breaking Elephant Bones a Million Years Ago

May 29, 2019

Why were archaic hominins making copies of stone tools out of pachyderm bones? Could it have been respect, hundreds of thousands of years before Homo sapiens even existed?

https://www.haaretz.com/archaeology/.premium.MAGAZINE-why-early-humans-were-breaking-elephant-bones-a-million-years-ago-1.7303057


------------------------------------


How poaching is changing the faces of African elephants

Mar 16, 2017

https://www.vox.com/science-and-health/2017/3/16/14939840/elephant-poaching-tuskless-tusk-evolution


------------------------------------


Brain Changes during Phyletic Dwarfing in Elephants and Hippos

2018

https://www.karger.com/Article/Fulltext/497268


-------------------------------------


An early, rabbit-sized elephant relative from Morocco

2009

https://www.nationalgeographic.com/science/phenomena/2009/07/07/an-early-rabbit-sized-elephant-relative-from-morocco/


------------------------------------


Paleocene emergence of elephant relatives and the rapid radiation of African ungulates

 June 30, 2009

https://www.pnas.org/content/106/26/10717


------------------------------------


Bodies Keep Shrinking on This Island, and Scientists Aren't Sure Why

https://www.nytimes.com/2018/08/02/science/pygmies-flores-evolution.html


-------------------------------------


Hybrid origins of the straight-tusked elephants

26 Feb 2018


http://johnhawks.net/weblog/reviews/genomics/elephant/elephant-palaeoloxodon-hybrids-2018.html


-------------------------------------


A chronicle of giant straight-tusked elephants

January 21, 2020

https://phys.org/news/2020-01-chronicle-giant-straight-tusked-elephants.html



------------------------------------



You Won’t Forget: The Difference between African and Asian Elephants








https://thomsonsafaris.com/blog/difference-african-asian-elephant/


--------------------------------



 How Do Teeth Become Tusks? (The Evolution)

https://www.readytosmile.com/2018/09/18/how-do-teeth-become-tusks-the-evolution/


--------------------------------


 How the rhino got his woolly

Aug 24th 2013

Ice-age giants like the woolly rhino may originally have been Tibetan

https://www.economist.com/science-and-technology/2013/08/24/how-the-rhino-got-his-woolly


------------------------------------


Woolly rhino fossil discovery in Tibet provides important clues to evolution of Ice Age giants

September 2, 2011

https://www.sciencedaily.com/releases/2011/09/110901142100.htm


------------------------------------


The story of rhinos and how they conquered the world

18 May 2015

Over the last 50 million years, rhinos have braved ice ages, prehistoric hyenas and giant crocodiles – and they were once the largest animals on land

http://www.bbc.com/earth/story/20150518-the-epic-history-of-rhinos


------------------------------------


Ancient rhinoceros tooth DNA from Georgia’s Dmanisi site in ‘game-changing’ evolutionary study

12 Sep 2019

https://agenda.ge/en/news/2019/2437


------------------------------------



What an elephant’s tooth teaches us about evolution

2016

To prove that evolutionary change isn’t always down to the genes, just open an elephant’s mouth …

https://www.theguardian.com/science/2016/jan/31/elephant-teeth-teach-about-evolution

 


------------------------------------


Here's a line-up of prehistoric beasts from the rhino family tree

2015

https://www.earthtouchnews.com/natural-world/evolution/heres-a-line-up-of-prehistoric-beasts-from-the-rhino-family-tree/


------------------------------------


1.7-Million-Year-Old Rhino Tooth Provides Oldest DNA Data Ever Studied

September 12, 2019

Researchers read the proteins preserved in the tooth enamel of an ancient rhino, a trick that may allow them to sequence fossils millions of years old

https://www.smithsonianmag.com/smart-news/million-year-old-rhino-tooth-provides-oldest-dna-data-180973117/


------------------------------------


Triceratops: Facts About the Three-Horned Dinosaur

March 18, 2016

https://www.livescience.com/24011-triceratops-facts.html


---------------------------------


[Evolution and functional morphology of primate facial skulls].

1993


https://www.ncbi.nlm.nih.gov/pubmed/8128757

Abstract

Both ontogenetically and phylogenetically the facial skull of primates consists of two components: the endocranial nasal capsule, and the exocranial membrane bones. The cartilaginous nasal capsule of the fetal period constitutes the framework for the nasal cavity, and it also functions as an expansive basis for the developing facial skull. In adult animals, its ossified parts form the fragile ethmoid bone. The structure of the nasal capsule is determined on the one hand by the spatial requirements of the orbits and of the nasal cavity (with respiratory and olfactory components), and on the other hand by the biomechanical properties of the chewing apparatus. The interaction of these heterogeneous factors results in complex, species-specific compromises. Primates are characterized by a gradual reduction of their olfactory system throughout evolution and by binocular vision. Their chewing apparatus shows constructional adaptations to a varying herbivorous diet. Viewed within a phylogenetic-systematic framework, primate evolution may be taken as a natural experiment that demonstrates the influence of various factors on a complex structural system such as the nasal and facial skeleton.



--------------------------------



Are Diet Preferences Associated to Skulls Shape Diversification in Xenodontine Snakes?

Abstract

Snakes are a highly successful group of vertebrates, within great diversity in habitat, diet, and morphology. The unique adaptations for the snake skull for ingesting large prey in more primitive macrostomatan snakes have been well documented. However, subsequent diversification in snake cranial shape in relation to dietary specializations has rarely been studied (e.g. piscivory in natricine snakes). Here we examine a large clade of snakes with a broad spectrum of diet preferences to test if diet preferences are correlated to shape variation in snake skulls. Specifically, we studied the Xenodontinae snakes, a speciose clade of South American snakes, which show a broad range of diets including invertebrates, amphibians, snakes, lizards, and small mammals. We characterized the skull morphology of 19 species of xenodontine snakes using geometric morphometric techniques, and used phylogenetic comparative methods to test the association between diet and skull morphology. Using phylogenetic partial least squares analysis (PPLS) we show that skull morphology is highly associated with diet preferences in xenodontine snakes.


https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0148375


--------------------------------


 Ancestor of all animals identified in Australian fossils

 March 23, 2020


A wormlike creature that lived more than 555 million years ago is the earliest bilaterian


Geologists have discovered the first ancestor on the family tree that contains most animals today, including humans. The wormlike creature, Ikaria wariootia, is the earliest bilaterian, or organism with a front and back, two symmetrical sides, and openings at either end connected by a gut. It was found in Ediacaran Period deposits in Australia and was 2-7 millimeters long, with the largest the size of a grain of rice.

 https://www.sciencedaily.com/releases/2020/03/200323152108.htm


--------------------------------



500-million-year-old worm 'superhighway' discovered in Canada

https://phys.org/news/2019-02-million-year-old-worm-superhighway-canada.html

Prehistoric worms populated the sea bed 500 million years ago—evidence that life was active in an environment thought uninhabitable until now, research by the University of Saskatchewan (USask) shows.

The sea bed in the deep ocean during the Cambrian period was thought to have been inhospitable to animal life because it lacked enough oxygen to sustain it.

But research published in the scientific journal Geology reveals the existence of fossilized worm tunnels dating back to the Cambrian period 270 million years before the evolution of dinosaurs.




--------------


You Share 70% of Your Genes with This Slimy Marine Worm

https://www.livescience.com/52843-acorn-worm-genome-sequencing.html


-------------


Worms and Humans Share the Same Life-Prolonging Gene

http://blogs.discovermagazine.com/d-brief/2015/12/03/life-prolonging-gene-found-in-worms-exists-in-humans/#.XHyDFbh7k2w


---------------



Evolution of the Major Lineages of Tapeworms (Platyhelminthes: Cestoidea) Inferred from 18S Ribosomal DNA and Elongation Factor-1α

https://www.jstor.org/stable/3285679?seq=1#page_scan_tab_contents



-----------------


Stem cells of worms, humans more similar than expected

The same regulatory mechanisms are active in the stem cells of flatworms and humans

https://www.sciencedaily.com/releases/2016/08/160809121428.htm


---------


Photos: 'Naked' Ancient Worm Hunted with Spiny Arms

https://www.livescience.com/57683-photos-naked-worm-cambrian-period.html


---------


Scientists Finally Solve Mystery of Tiny, Ancient Worm’s 'Mismatched' Head and Body

2019

https://www.livescience.com/64857-ancient-worm-hidden-jaws.html


------------


480-Million-Year-Old Mystery Creature Finally Identified from Its Preserved Guts

https://www.livescience.com/64832-ancient-starfish-relative-mystery-solved.html


-------------


The terrifying bobbit worm has a huge ancient cousin

Bobbit worms belong to a vast group called the polychaetes (or "bristle worms"), which contains several thousand species ranging in size from just a few millimetres to a few metres long. Today, these creatures are found all over the oceans, and besides the larger predators, they also include tiny free-swimming clam worms, long-lived cold seep tubeworms and bone-eating Osedax worms.



------------


How Giant Tube Worms Survive at Hydrothermal Vents | I Contain Multitudes

https://www.youtube.com/watch?v=8W_ywzhkR90


---------------


BLOODWORMS - Will They BITE?!

https://www.youtube.com/watch?v=o7aM5gU8mFY


-------------


Worms With A Copper Smile

Mineral Composite in Glycera Jaws Imparts Strength, Abrasion Resistance

https://pubs.acs.org/cen/critter/worms1.html

Lichtenegger and her colleagues used a combination of X-ray diffraction, electron microscopy, and other techniques to determine the chemical composition and mechanical properties of the worm's jaws. The carnivorous worm uses the hard, sharp-tipped structures to bite and inject venom into its prey.

The tip region of the jaws contains layers of polycrystalline atacamite fibrils dispersed in a protein matrix, the researchers find. The fibrils, which align with the jaw's outer contour, are about 80 nm in diameter and 1210 mm long. They are concentrated toward the center of the tip, while the base region is devoid of fibrils. The hardness and stiffness of the jaw increases from the base to the tip and from the surface to the interior, which correlates with the increasing degree of mineralization

Cross-sectional maps of copper and chloride concentration confirm the elemental distribution in the jaw and show that the Cu-Cl ratio is higher than that found in atacamite, suggesting that free copper ions are present. Copper is known to cross-link polymers and protein scaffolds, the researchers point out, and the excess copper in the worm's jaw could be playing that role.

The jaw's impressive structural stability and resistance to abrasion approaches that of human tooth enamel, the team notes--even though atacamite makes up only 4% of the worm's jaw, while hydroxyapatite, Ca5(PO4)3OH, makes up 96% of tooth enamel. This toughness is needed to protect the jaw from wear and tear as the worm burrows through gritty marine sediment where it may chomp indiscriminately on bits of gravel.



-------------


Worm's Use of Copper Could Point to Novel Material Designs

https://www.scientificamerican.com/article/worms-use-of-copper-could/


--------------


 Cool Evolution Trick: Platinum Turns Baby Snails Into Slugs

2010


https://www.wired.com/2010/10/snails-slugs-shell-evolution/


--------------------------------------------



 This Iron-Shelled Snail Is Totally Metal … And Now It’s Endangered

July 24, 2019

https://www.livescience.com/66017-metal-snail-endangered.html







(The scaly-foot snail is also known as the sea pangolin for its "armor" made of overlapping scales).



------------------------------


Snail Teeth Found to Be Strongest Natural Material

 2/18/15

You may have heard that spider silk is the strongest material in the natural world. That used to be true, but now scientists have identified something even stronger: the teeth of limpets, a type of aquatic snail.










(Next step could be limpet-tooth body armor).

https://www.newsweek.com/snail-teeth-found-be-strongest-natural-material-307707


-------------------------------



Uncovering the Secrets of Abalone Body Armor


https://jacobsschool.ucsd.edu/news/news_releases/release.sfe?id=327


San Diego, CA, January 14, 2005 -- Engineering researchers at the University of California, San Diego are using the shell of a seaweed-eating snail as a guide in the development of a new generation of bullet-stopping armor. The colorful oval shell of the red abalone is highly prized as a source of nacre, or mother-of-pearl, jewelry, but the UCSD researchers are most impressed by the shell’s ability to absorb heavy blows without breaking.

In a paper published in the Jan. 15 issue of Materials Science and Engineering A, Marc A. Meyers,  a professor in UCSD’s Jacobs School of Engineering, and engineering graduate student Albert Lin explain in detail for the first time the steps taken by the abalone to produce a helmet-like home made with 95 percent calcium carbonate “tiles” and 5 percent protein adhesive. Teachers who write on blackboards know that calcium

carbonate, or chalk, is weak and brittle, but Meyers and Lin have demonstrated that a highly ordered brick-like tiled structure created by the mollusk is the toughest arrangement of tiles theoretically possible.

The abalone shell investigation is one of a growing number of science-mimicking-nature, or biomimetic, projects at UCSD. For example, Meyers also is analyzing the strong, but extremely lightweight bill of the Toco Toucan, a Central and South American bird that squashes fruit and berries with its banana-shaped bill. “We are actually interested in basic research on new materials,” said Meyers. “We have turned to nature because millions of years of evolution and natural selection have given rise in many animals to some very sturdy materials with surprising mechanical properties.”

Other biomimetic projects at UCSD include development of a new artificial limb technology that relies on bars and wires, new drug synthesis techniques invented to duplicate those of microorganisms, and “epidemiology-based” techniques designed to detect and defend against viruses, worms and other plagues afflicting the Internet.




















(The mother-of-pearl growth surface of abalone shell is colored due to the way light refracts as it strikes tiny terraces of calcium carbonate).















  (UCSD engineering researchers showed that the terraced,
   Christmas tree-like surface of abalone shell has evenly spaced
   nucleation sites from which stacks of hexagonal “tiles” of calcium
   carbonate begin to grow. The top and bottom surfaces of each
   layer of tiles are separated by a protein adhesive, but the
   adhesive does not bind the edges of tiles to adjoining tiles).



---------------------------------------------



Mitochondrial evolution in snails gives hints on the adaptations from sea to land and beyond

25 Aug 2016

https://blogs.biomedcentral.com/bmcseriesblog/2016/08/25/mitochondrial-evolution-snails-gives-hints-adaptations-sea-land-beyond/



--------------------------------------------




 EVOLUTION OF ADAPTATION THROUGH ALLOMETRIC SHIFTS IN A MARINE SNAIL

2006

https://www.eeob.iastate.edu/faculty/adams/files/page/files/2006-hollanderetal-evolution.pdf


-------------------------------


A speciation gene for left–right reversal in snails results in anti-predator adaptation

2010

https://www.nature.com/articles/ncomms1133


------------------------------


How the snail's shell got its coil: Single gene that causes a rightward swirl in the gastropod's hard exterior is found by scientists - and creatures missing the DNA have a 'sinister' lefty spiral


14 May 2019


    Experts identified a gene that causes rightward chirality in freshwater snails
    Scientists say it could explain why our hearts are on the left and livers right
    'Lefty' snails are rarely found in nature and are shunned as mating partners
    Jeremy the 'lefty' snail's failed hunt for love went viral on social media in 2017


https://www.dailymail.co.uk/sciencetech/article-7026899/Single-gene-causes-rightward-swirl-snails-shells-identified.html


------------------------------


Tweaking one gene with CRISPR switched the way a snail shell spirals

The first gene-edited snails confirm which gene is responsible for how a shell swirls

May 14, 2019

https://www.sciencenews.org/article/tweaking-one-gene-crispr-switched-way-snail-shell-spirals


--------------------------------



A delicacy now, snails in the human diet may have meant survival 150,000 years ago

26 October, 2015

https://www.ancient-origins.net/news-evolution-human-origins/delicacy-now-snails-human-diet-may-have-meant-survival-150000-years-ago-020589


--------------------------------------


Evolution and development of the cartilaginous skull: From a lancelet towards a human face

July 2019

https://www.sciencedirect.com/science/article/pii/S1084952117301453


----------------------------------



SNAPSHOT: Evolution of a Snail Color Debate

February 27, 2019


https://www.discovermagazine.com/planet-earth/snapshot-evolution-of-a-snail-color-debate



------------------------------



Artemia habitats: Ion concentrations tolerated by one superspecies

1988


https://link.springer.com/article/10.1007/BF00026278


Abstract

The geographic distribution, history, and ionic composition of habitats of Artemia franciscana are reviewed with emphasis on habitats with extreme values for ionic concentrations or ionic ratios: a) high-chloride waters (sea water salterns and Zuni and Great Salt Lakes); b) high-sulfate lakes in Saskatchewan (Chaplin and Little Manitou) and on the Okanogan plateau of Washington (Penley Lake complex); and c) high-carbonate habitats in Nevada (Fallon), in California (Mono Lake) and in the Nebraska sandhills (Jesse and Antioch).

First-instar nauplii from populations representative of each of these three habitat clusters were tested for tolerance of potassium (0–5 g K l-1), magnesium (0–1.3 g Mg l-1), and calcium (0\2–0.6 g Ca l-1). Viabilities were recorded until survivors reached adulthood in pairs of simple defined synthetic culture media which differed in only one parameter. Eight populations showed four levels of tolerance of high potassium. Of four populations tested, all had high viability and fertility in media lacking potassium (above the level in the yeast diet).

Artemia from sea water salterns or from Zuni, Chaplin, or Great Salt Lakes could not tolerate low levels of calcium (<20 mg l-1). This accounts for their inability to tolerate hypersaline high-carbonate waters. Mono and Fallon nauplii had high viability and fertility in media with low levels of calcium (0–10 mg l-1) but lacking magnesium. They could not survive for seven days, however, in low-calcium (< 10 mg l-1) media that contained moderate amounts of magnesium (1.3 g l-1), indicating that magnesium interferes with utilization of low levels of calcium.

For each of the three cations, the range of concentrations encountered by each population in the habitat is narrower than the range affording high viability in laboratory media. As expected, the midpoints of the two ranges are sometimes similar. In many cases, however, the narrower range of ionic concentrations reported for lake water is at the end of the range affording high viability in the laboratory.



--------------------------------


Giant Viruses Invent Genes Shared by No Life on Earth

Giant viruses may invent genes and proteins found nowhere else on Earth, new research suggests.

As their name implies, giant viruses are big — as big as bacteria, and more than twice the size of typical viruses, scientists have previously reported. Giant viruses have more complex genomes than some simple microbial organisms, and many of their genes code for proteins found only in giant viruses, according to past studies.

https://www.livescience.com/62804-giant-viruses-evolve-unique-genes.html


--------------


Fitness of Leishmania donovani Parasites Resistant to Drug Combinations

https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0003704


-------------


Genetically Modified Live Attenuated Leishmania donovani Parasites Induce Innate Immunity through Classical Activation of Macrophages That Direct the Th1 Response in Mice

https://iai.asm.org/content/83/10/3800


--------------------


Leishmania donovani

Leishmania donovani is a species of intracellular parasites belonging to the genus Leishmania, a group of haemoflagellate kinetoplastids that cause the disease leishmaniasis. It is a human blood parasite responsible for visceral leishmaniasis or kala-azar, the most severe form of leishmaniasis. It infects the mononuclear phagocyte system including spleen, liver and bone marrow. Infection is transmitted by species of sandfly belonging to the genus Phlebotomus in Old World and Lutzomyia in New World. Therefore, the parasite is prevalent throughout tropical and temperate regions including Africa (mostly in Sudan), China, India, Nepal, southern Europe, Russia and South America. It is responsible for thousands of deaths every year and has spread to 88 countries, with 350 million people at constant risk of infection and 0.5 million new cases in a year.

https://en.wikipedia.org/wiki/Leishmania_donovani


----------------------


Genetically modified live attenuated parasites as vaccines forleishmaniasis

https://pdfs.semanticscholar.org/5110/bf19e66a80a3f02cb306e281b747ccf99b04.pdf


--------------


Largest parasitic worm genetic study hatches novel treatment possibilities
Study helps understand how parasitic worms cause disease and uncovers potential new de-worming medicines

https://www.sciencedaily.com/releases/2018/11/181105122530.htm


---------------


 Genetically modified Plasmodium parasites as a protective experimental malaria vaccine.

https://www.ncbi.nlm.nih.gov/pubmed/15580261

Abstract

Malaria is a mosquito-borne disease that is transmitted by inoculation of the Plasmodium parasite sporozoite stage...


----------------


 Success Shown in Humans with Genetically Engineered Malaria Parasite Vaccine

https://www.cidresearch.org/articles/success-shown-in-humans-with-genetically-engineered-malaria-parasite-vaccine


------------------


Human anaerobic intestinal “rope” parasites

https://arxiv.org/ftp/arxiv/papers/1301/1301.0953.pdf


-------------------


Tropical Diseases: Can CRISPR help in the fight against parasitic worms?

https://elifesciences.org/articles/44382


------------------


 How a nasty, brain-eating parasite could help us fight cancer

 The team of investigators behind the new study set out to harness the immune system’s reaction to the presence of the parasite Toxoplasma gondii (T. gondii), which can be found in cat faeces, as a tool to cure ovarian cancer..

In the field of parasitology no single parasite is as popular as T. gondii. This single-cell parasite, which affects one third of the world’s human population, is best known for its ability to invade and damage the brain and alter the behaviour of affected individuals..

http://theconversation.com/how-a-nasty-brain-eating-parasite-could-help-us-fight-cancer-64267


-----------------


Genetic Manipulation of the Toxoplasma gondii Genome by Fosmid Recombineering

https://mbio.asm.org/content/5/6/e02021-14


--------------------


Genetic modifications of cytokine genes and Toxoplasma gondii infections in pregnant women

https://www.sciencedirect.com/science/article/pii/S0882401017304588


---------------------


QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii

https://www.jove.com/video/55185/qtl-mapping-crisprcas9-editing-to-identify-drug-resistance-gene


---------------


 Genetic Protection For Plants Against Parasitic Worm Attack

Read more at: https://ascienceenthusiast.com/genetic-plants-parasitic-worm/


------------------


Genetically modified bacteria could deter crop parasites

https://microbiologysociety.org/news/society-news/genetically-modified-bacteria-could-deter-crop-parasites.html


---------------


 What leeches and ligers can teach you about evolution

https://boingboing.net/2013/04/24/leeches-are-a-hypothesis-why.html


-----------------


 Bacterial symbiont and salivary peptide evolution in the context of leech phylogeny.

Abstract

The evolutionary history of leeches is employed as a general framework for understanding more than merely the systematics of this charismatic group of annelid worms, and serves as a basis for understanding blood-feeding related correlates ranging from the specifics of gut-associated bacterial symbionts to salivary anticoagulant peptides. A variety of medicinal leech families were examined for intraluminal crop bacterial symbionts. Species of Aeromonas and Bacteroidetes were characterized with DNA gyrase B and 16S rDNA. Bacteroidetes isolates were found to be much more phylogenetically diverse and suggested stronger evidence of phylogenetic correlation than the gammaproteobacteria. Patterns that look like co-speciation with limited taxon sampling do not in the full context of phylogeny. Bioactive compounds that are expressed as gene products, like those in leech salivary glands, have 'passed the test' of evolutionary selection. We produced and bioinformatically mined salivary gland EST libraries across medicinal leech lineages to experimentally and statistically evaluate whether evolutionary selection on peptides can identify structure-function activities of known therapeutically relevant bioactive compounds like antithrombin, hirudin and antistasin. The combined information content of a well corroborated leech phylogeny and broad taxonomic coverage of expressed proteins leads to a rich understanding of evolution and function in leech history.


https://www.ncbi.nlm.nih.gov/pubmed/21729354


--------------------


 Marine Leech Anticoagulant Diversity and Evolution.

https://www.ncbi.nlm.nih.gov/pubmed/29505345

Leeches (Annelida: Hirudinea) possess powerful salivary anticoagulants and, accordingly, are frequently employed in modern, authoritative medicine. Members of the almost exclusively marine family Piscicolidae account for 20% of leech species diversity, and they feed on host groups (e.g., sharks) not encountered by their freshwater and terrestrial counterparts. Moreover, some species of Ozobranchidae feed on endangered marine turtles and have been implicated as potential vectors for the tumor-associated turtle herpesvirus. In spite of their ecological importance and unique host associations, there is a distinct paucity of data regarding the salivary transcriptomes of either of these families. Using next-generation sequencing, we profiled transcribed, putative anticoagulants and other salivary bioactive compounds that have previously been linked to blood feeding from 7 piscicolid species (3 elasmobranch feeders; 4 non-cartilaginous fish feeders) and 1 ozobranchid species (2 samples). In total, 149 putative anticoagulants and bioactive loci were discovered in varying constellations throughout the different samples. The putative anticoagulants showed a broad spectrum of described antagonistic pathways, such as inhibition of factor Xa and platelet aggregation, which likely have similar bioactive roles in marine fish and turtles. A transcript with homology to ohanin, originally isolated from king cobras, was found in Cystobranchus vividus but is otherwise unknown from leeches. Estimation of selection pressures for the putative anticoagulants recovered evidence for both positive and purifying selection along several isolated branches in the gene trees, and positive selection was also estimated for a few select codons in a variety of marine species. Similarly, phylogenetic analyses of the amino acid sequences for several anticoagulants indicated divergent evolution.


---------------------


The Evolution of Parental Care in Freshwater Leeches

https://www.sciencedirect.com/science/article/pii/S1431761304700336

Summary

The life-history strategies of a selection of the most common European freshwater leeches (Euhirudinea) are described. On the basis of this information and results from the literature, the probable phylogenetic development of parental care in the Euhirudinea is reconstructed. The jawless worm leeches (Erpobdellidae) secrete a protective cocoon, cement it to the substrate and sometimes ventilate it before they leave the egg capsules. This behaviour represents the most ancient state in leech evolution. Members of the jawed Hirudinidae deposit desiccation-resistant cocoons on land. All known Glossiphoniidae (leeches equipped with a proboscis) have evolved the habit of brooding the eggs and young. These unique parental care patterns within one family of extant freshwater leeches can be arranged schematically in a series of increasing complexity which may reflect the evolution of brooding behaviour. Glossiphoniid leeches of the genus Helobdella, which have a world-wide distribution, display the most highly developed parental care system: they not only protect but also feed the young they carry. This results in the young being much larger when they leave the parent and, presumably, in higher subsequent survival. Isolated cocoons of all aquatic leeches are rapidly destroyed by predators, primarily water snails. In erpobdellids (but not glossiphoniids, which protect the cocoons) a large portion of the cocoons are lost due to predatory attacks. We conclude that the major selective pressure driving the evolution of parental care in leeches may have been predation on eggs and juvenile stages.


----------------------


On the origin of leeches by evolution of development

https://onlinelibrary.wiley.com/doi/full/10.1111/dgd.12573


--------------------


Monster leech swallows giant worm - Wonders of the Monsoon: Episode 4 - BBC Two

https://www.youtube.com/watch?time_continue=72&v=0fGGz6d3vC4


----------------------


Massive Australian earthworm can grow up to 9 feet long [7 pictures]

https://twentytwowords.com/massive-australian-earthworm-can-grow-up-to-9-feet-long-7-pictures/


-------------------


Nature Blows My Mind! World's largest earthworm can grow to 9 ft. long

https://www.treehugger.com/natural-sciences/nature-blows-mind-worlds-largest-gippsland-worm.html


----------------


Giant Gippsland earthworm

https://en.wikipedia.org/wiki/Giant_Gippsland_earthworm


---------------


Divers Discover Huge 26-foot Deep-sea Worm

https://weather.com/news/trending/video/divers-discover-huge-26-foot-deep-sea-worm

 

--------------------


Worm evolves to eat corn that was genetically engineered to kill it

https://www.independent.co.uk/news/science/worm-evolves-to-eat-corn-that-was-genetically-engineered-to-kill-it-9199667.html


-----------------


 How Genetically Modified Corn Is Creating Super Worms

https://thinkprogress.org/how-genetically-modified-corn-is-creating-super-worms-4d5fdbebb848/


------------------


 Genetic Protection For Plants Against Parasitic Worm Attack

Read more at: https://ascienceenthusiast.com/genetic-plants-parasitic-worm/


------------------


Genetically modified bacteria could deter crop parasites

https://microbiologysociety.org/news/society-news/genetically-modified-bacteria-could-deter-crop-parasites.html


------------


 Caenorhabditis elegans

https://en.wikipedia.org/wiki/Caenorhabditis_elegans

Caenorhabditis elegans is a free-living, transparent nematode, about 1 mm in length, that lives in temperate soil environments. It is the type species of its genus. The name is a blend of the Greek caeno- (recent), rhabditis (rod-like) and Latin elegans (elegant). In 1900, Maupas initially named it Rhabditides elegans, Osche placed it in the subgenus Caenorhabditis in 1952, and in 1955, Dougherty raised Caenorhabditis to the status of genus.

C. elegans is an unsegmented pseudocoelomate and lacks respiratory or circulatory systems. Most of these nematodes are hermaphrodites and a few are males. Males have specialised tails for mating that include spicules.

C. elegans is notable in animal sleep studies as the most primitive organism to display sleep-like states. In C. elegans, a lethargus phase occurs shortly before each moult.


--------------


Rapid Experimental Evolution of Pesticide Resistance in C. elegans Entails No Costs and Affects the Mating System

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580027/


----------------


Giant Viruses Invent Genes Shared by No Life on Earth

https://www.livescience.com/62804-giant-viruses-evolve-unique-genes.html


--------------------------------



Human evolution





https://www.britannica.com/science/human-evolution




--------------------------------





The evolution of whales



 https://evolution.berkeley.edu/evolibrary/article/evograms_03


The first thing to notice on this evogram is that hippos are the closest living relatives of whales, but they are not the ancestors of whales. In fact, none of the individual animals on the evogram is the direct ancestor of any other, as far as we know. That's why each of them gets its own branch on the family tree.
























(Skeletons of two early whales).















(As whales evolved increasingly aquatic lifestyles, they also evolved nostrils located further and further back on their skulls).



--------------------------------



Fossil skull sheds new light on transition from water to land

16 Mar 2015

The first 3D reconstruction of the skull of a 360 million-year-old near-ancestor of land vertebrates has been created by scientists.

https://www.cam.ac.uk/research/news/fossil-skull-sheds-new-light-on-transition-from-water-to-land



--------------------------------



Mammal Forerunner that Reproduced Like a Reptile Sheds Light on Brain Evolution

A newly described fossil of an extinct mammal relative — and her 38 babies — is among the best evidence that a key development in the evolution of mammals was trading brood power for brain power.


 



https://news.utexas.edu/2018/08/29/mammal-forerunner-sheds-light-on-brain-evolution/




-----------------------------------------------------------------------------------




What birds can teach us about evolution

2018



 









https://www.nhm.ac.uk/discover/news/2018/october/what-birds-can-teach-us-about-evolution.html




----------------------------------------------------------------------------------





Hualongdong Skull Is Latest Challenge To Dominant Human Evolution Model

2019








https://www.discovermagazine.com/planet-earth/hualongdong-skull-is-latest-challenge-to-dominant-human-evolution-model


Researchers created a virtual reconstruction of the mostly complete Hualongdong skull (yellow) by mirror-imaging the missing pieces (gray). Stone tools found at the site appear in lower corners of the image. (Credit: Wu Xiujie) A largely complete, roughly 300,000-year-old skull from southeastern China appears to be the latest evidence challenging the dominant model of human evolution. The Hualongdong skull's unique combination of features make the fossil a tantalizing clue to East Asia's diverse hominin history. Researchers excavating a collapsed cave site unearthed the skull, formally known as Hualongdong 6 (HLD 6), along with additional partial fossils of archaic humans and animals, plus assorted stone tools, over the last decade or so. Using the ages of surrounding mineral deposits and other material in the cave, the team determined the skull and other remains were about 300,000 years old. Unlike many East Asian archaic human fossils, which are often fragmentary, the Hualongdong skull is nearly complete, and in decent shape, allowing the team to draw some firm conclusions about its anatomy. And that's where things get really interesting. Traits That Are Not Straightforward HLD 6 exhibits a suite of traits consistent with other archaic human remains from East Asia, such as a low and wide cranial vault (sometimes imprecisely called the skullcap), a low and wide nasal aperture (the pear-shaped opening in the skull for a schnoz) and reduced or absent third molars. However, the Hualongdong skull also has a few features that seem transitional toward anatomically modern humans (AMHs). Unlike the chinless, projecting faces of archaic humans and their ancestors, HLD 6 had a relatively flat face and somewhat of a chin. The evolution of the chin has long been debated in paleoanthropology circles, but everyone agrees only Homo sapiens have prominent ones. HLD 6 is not the first East Asian skull to sport an unusual combination of traits. For example, the partial Xuchang skulls from Central China, at least 100,000 years old, have a different collection of mosaic traits, blending archaic and modern human anatomy with that of Neanderthals. The Hualongdong fossils are also by no means the oldest hominin remains found in East Asia; multiple specimens of Homo erectus and related lineages have been unearthed going back more than 1.6 million years. A 2018 study of more than 100 tools from Shangchen suggested that archaic hominins were in China 2.1 million years ago, though no hominin fossils of that age have turned up (yet). So, while it's not a shocking find, HLD 6 is still significant. To understand why, we have to wade into one of the more contentious debates in human evolution. From Many, One? Or From One, Many? For decades, particularly in the West, the Recent African Origin model of human evolution (RAO) has dominated. According to this hypothesis, AMHs evolved in Africa and then, in the last 50,000-80,000 or so years, spread out across Eurasia, displacing or absorbing any isolated populations of archaic humans still hanging on. Over the last decade, new fossil finds outside Africa have pushed back the dispersal date, though not all RAO proponents accept evidence of an earlier departure. Staunch advocates of the long-standing theory typically consider finds such as Israel's Misliya-1 partial jaw, at least 170,000 years old, as evidence only that a couple AMHs may have wandered out of Africa super early but didn't get very far. Meanwhile, an alternate model of human evolution, Multiregionalism or Regional Continuity, has gained traction, particularly in East Asia. According to multiregionalists, when H. erectus left Africa almost 2 million years ago, these early explorers didn't die out. They fanned out across Eurasia and continued to evolve, eventually becoming regional populations of H. sapiensbefore other populations of H. sapiens left Africa. The differences between the models may seem insignificant to outsiders — for example, both models acknowledge interbreeding occurred in the last 100,000 years between the various populations of archaic and modern humans — but these competing paths of human evolution disagree over some of the core issues of our deep past, including how we define a species and what makes us human. In the last two years, some researchers have proposed a third model that tries to reconcile the dueling models and the expanding fossil record, acknowledging the complexity of our origin story. So let's get back to HLD 6. The skull has some traits that are consistent with other archaic members of the genus Homo that have been found in East Asia. It also has features that hint at traits unique to AMHs, which have not been found outside of Africa earlier than about 180,000 years ago (and that's the Misliya-1 fossil, found in Israel, essentially on the edge of the African continent). At about 300,000 years old, HLD 6 may be evidence of regional continuity, a transitional human that represents the evolution of archaic East Asian H. erectus populations into East Asian AMHs. Or, quite frankly, HLD 6 may simply be an anomaly, an archaic hominin with some quirky variations. Until researchers find more fossils, the Hualongdong skull will probably be interpreted according to whatever bias you bring to the table. The HLD 6 study was published in Proceedings of the National Academy of Sciences (PNAS).



--------------------------------



Analysis of Early Hominins

https://www2.palomar.edu/anthro/hominid/australo_2.htm



--------------------------------



 Skull of Homo erectus throws story of human evolution into disarray

2013

A haul of fossils found in Georgia suggests that half a dozen species of early human ancestor were actually all Homo erectus

https://www.theguardian.com/science/2013/oct/17/skull-homo-erectus-human-evolution



--------------------------------



Our Skulls Are Out-Evolving Us

Sep 19, 2019

A motley crew of scientists argue that our ever-shrinking skulls are wreaking havoc on our well-being

Over the last 250 years, our skulls have morphed in dangerous and troubling ways.






https://onezero.medium.com/our-skulls-are-out-evolving-us-and-that-could-mean-a-public-health-crisis-f950faed696d



--------------------------------



Snake Skulls Clarify How History's Creepiest Animals Lost Their Legs

2018

Snakes evolved from lizards, and then what?

https://www.inverse.com/article/40596-snake-evolution-lizard-university-of-helsinki



--------------------------------


How Dinosaurs Shrank and Became Birds

June 2, 2015

Modern birds appeared to emerge in a snap of evolutionary time. But new research illuminates the long series of evolutionary changes that made the transformation possible.

https://www.quantamagazine.org/how-birds-evolved-from-dinosaurs-20150602/


--------------------------------


TAXONOMIC ASPECTS OF AVIAN HYBRIDIZATION

https://sora.unm.edu/sites/default/files/journals/auk/v086n01/p0084-p0105.pdf


---------------------------------------------------------------------------------


 Islands Helped Penguins Evolve. Then Hungry Humans Showed Up.

Feb. 8, 2019

The discovery of two extinct penguin subspecies in New Zealand is a cautionary tale of the threats faced by the waddling birds in the wild.

https://www.nytimes.com/2019/02/08/science/penguins-islands-extinctions.html


---------------------------------------------------------------------------------


Ice sheets promote speciation in boreal birds

http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC1691815&blobtype=pdf


-------------------------------------------------------------------------------



Consequences of divergence and introgression for speciation in Andeancloud forest birds

2016

https://deepblue.lib.umich.edu/bitstream/handle/2027.42/137772/evo13251.pdf?sequence=1



-------------------------------


Birds' unique skulls linked to young dinosaur brains

 2017

https://phys.org/news/2017-09-scientists-track-brain-skull-transition-dinosaurs.html


--------------------------------


Human evolution

https://www.maropeng.co.za/content/page/human-evolution


--------------------------------


Tracing the Evolution of the Human Brain Through Casts of the Inner Skull

October 25, 2015

https://www.mentalfloss.com/article/70306/tracing-evolution-human-brain-through-casts-inner-skull


--------------------------------



Wow, Dogs Really Don’t Like Black People


If Fido turns feisty around your Black friends, you may have a racist dog on your hands


ome people would argue I’m doing something to provoke these innocent Fidos. It’s entirely possible some sort of voodoo slave magic emanates from my core, and that’s what’s making all of the doggies I run into hate me so much. Or maybe I’m actually a huge bitch and I use Black telepathic powers to communicate with dogs that I hate them. Some may assume I act afraid around dogs. And that’s what encourages them to attack me.


But I think it’s because a lot of White people’s dogs just don’t like Black people.


Some professionals argue that dogs’ evolutionary history impels them to protect the pack when danger approaches. In 2020, the “pack” is their owner. Dogs also pick up on their owner’s biased fear responses, regardless of the level of subtlety. An increased heart rate. A rise in body temperature. A barely discernible increase in the tug on their collar. Change in tone of voice while saying “hi” to the Black person approaching both owner and dog. All of this alerts the dog that their owner’s in danger. So they react by growling and barking at the Black person threatening the safety of the vicinity.


Other people attribute the phenomenon of racists dogs to the fact that White people’s dogs simply aren’t around Black people often enough to trust them. These poor dogs are victims of circumstance. They’re forced to live in ethnic deserts where only White people dot the landscape.


When a Black person finally does jaunt into their vision, they don’t see human beings. They see dark-skinned specters shucking and jiving… err, I mean, walking toward them down the sidewalk. It’s akin to seeing Bigfoot, or a gray alien approaching you for the first time. It’s only natural for dogs to jump and bark as a reaction.


But Black people have an evolutionary history as well. Attack dogs and police canines have long been used to terrorize and intimidate Black Americans during interactions with law enforcement. It’s only natural for us to be a little cautious around man’s best friend, who has seldom been friendly to us.


    Dogs also pick up on their owner’s biased fear responses, regardless of the level of subtlety.


Look. I get it. White people don’t intend for their dogs to hate Black people. But can we all acknowledge this is a Black experience that needs to be addressed broadly across American culture? As a 30-something-year-old Black woman living in Los Angeles, it degrades my sense of safety to the point that I needed to write a partially tongue-in-cheek article about it on Medium.



https://zora.medium.com/wow-dogs-really-dont-like-black-people-f7618445b43a



------------------------------------------------------



New evidence shows that domestication of dogs has changed their skull shapes

18/10/2017

https://www.zoo.cam.ac.uk/news/domesticated-dog-skull-shape



-------------------------------------------------------



Patterns of integration in the canine skull: An inside view into the relationship of the skull modules of domestic dogs and wolves

August 2017

https://www.researchgate.net/publication/319190514_Patterns_of_integration_in_the_canine_skull_An_inside_view_into_the_relationship_of_the_skull_modules_of_domestic_dogs_and_wolves



-------------------------------------------------------



Wolf-to-dog transition had little to do with humans, ancient skull suggests

December 18, 2011

The “extraordinary preservation” of a 33,000-year-old skull — found in a cave in southern Siberia — has helped show that dog domestication “was, in most cases, entirely natural” and not really a “human accomplishment,” says B.C. evolutionary biologist Susan Crockford

https://nationalpost.com/news/wolf-to-dog-transition-had-little-to-do-with-humans-ancient-skull-suggests



--------------------------------------------------------



Prehistoric fossils suggest modern dogs evolved from a single population of wolves

Jul 18, 2017

https://www.theverge.com/2017/7/18/15992572/dog-genetics-archaeology-fossils-evolution-domestication-wolves




-------------------------------------------------------



 40,000-year-old severed wolf's head discovered in Siberia

 June 12, 2019

https://www.cnn.com/2019/06/11/europe/russia-wolf-head-scli-intl/index.html


--------------------------------------------------------



The self-domestication hypothesis: evolution of bonobo psychologyis due to selection against aggression

2011

https://evolutionaryanthropology.duke.edu/sites/evolutionaryanthropology.duke.edu/files/site-images/hare-et-al-2012-self-domestication.original.pdf


-------------------------------------------------------


Human meddling has manipulated the shapes of different dog breeds’ brains

September 2, 2019

Distinct shapes of pooches’ brain regions aren’t solely due to the animals’ size or head shape

https://www.sciencenews.org/article/dogs-breed-brain-shape-humans


-------------------------------------------------------


Large-Scale  Diversification  of  Skull  Shape  in  Domestic Dogs:  Disparity  and  Modularity

2009

https://morphometrics.uk/PDF_files/AmNat2010.pdf



-------------------------------------------------------



Toward understanding dog evolutionary and domestication history

 March 2011

https://www.sciencedirect.com/science/article/pii/S1631069110003008



------------------------------------------------------


Out of Asia: An Allopatric Model for the Evolution of the Domestic Dog

2013

https://www.hindawi.com/journals/isrn/2013/841734/



------------------------------------------------------



Domestic dogs may have evolved separately in Europe and Asia

2 June 2016

https://www.newscientist.com/article/2091836-domestic-dogs-may-have-evolved-separately-in-europe-and-asia/



------------------------------------------------------



Novel contributions in canine craniometry: Anatomic and radiographic measurements in newborn puppies

May 8, 2018

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196959



--------------------------------




 K-9 skull study may help children with craniofacial deformities

 Feb 11, 2013

http://www.digitaljournal.com/article/343261

 


----------------------------------


Ancient Dog Skull Shows Early Pet Domestication

2011

33,000-year-old fossil suggests dogs arose in multiple places, study says.

https://www.nationalgeographic.com/news/2011/8/110819-dogs-wolves-russia-domestication-animals-science-evolution/



--------------------------------



 Morphogenesis of Canine Chiari Malformation and Secondary Syringomyelia: Disorders of Cerebrospinal Fluid Circulation

 27 July 2018

https://www.frontiersin.org/articles/10.3389/fvets.2018.00171/full



--------------------------------



Females Live Longer Than Males In Majority Of Wild Mammals

March 27, 2020

https://www.iflscience.com/plants-and-animals/females-live-longer-than-males-in-majority-of-wild-mammals/



--------------------------------



On the lack of a universal pattern associated with mammalian domestication: differences in skull growth trajectories across phylogeny

25 October 2017

https://royalsocietypublishing.org/doi/full/10.1098/rsos.170876

 


--------------------------------


Ancient Coelacanth Fish Study Reveals Insights On Skull Evolution

2019

https://www.techtimes.com/articles/241858/20190419/ancient-coelacanth-fish-study-reveals-insights-on-skull-evolution.htm


--------------------------------


Newly found species fills evolutionary gap between fish and land animals

Paleontologists have discovered fossils of a species that provides the missing evolutionary link between fish and the first animals that walked out of water onto land about 375 million years ago. The newly found species, Tiktaalik roseae, has a skull, a neck, ribs and parts of the limbs that are similar to four-legged animals known as tetrapods, as well as fish-like features such as a primitive jaw, fins and scales.

http://www-news.uchicago.edu/releases/06/060405.tiktaalik.shtml


---------------------------------


A tiny skull fossil suggests primate brain areas evolved separately

2019

Digital reconstruction hints that the organ’s development over time was complicated

https://www.sciencenews.org/article/skull-fossil-suggests-primate-brain-areas-evolved-separately


--------------------------------


Dental and Skull Anatomy of Carnivores, Herbivores, and Omnivores

https://www.mainstreetsmiles.com/dental-and-skull-anatomy-of-carnivores-herbivores-and-omnivores/


--------------------------------


Why we have a spine, when over 90% of animals don't

2016

Although the backbone is one of the most important innovations in the history of life, its origins have long been shrouded in mystery

 http://www.bbc.com/earth/story/20160812-why-we-have-a-spine-when-over-90-of-animals-dont


--------------------------------


Coelacanth Reveals Secrets of Vertebrate Skull Evolution

Apr 23, 2019

http://www.sci-news.com/biology/coelacanth-brain-skull-07118.html


---------------------------------


Ancient Skull Shows What the Last Common Ancestor of Apes and Humans Looked Like

8/11/2017

The 13-million-year-old infant skull was unearthed in Kenya in 2014 and will help researchers understand how climate, ecology, geography, and other factors were key to evolution.

https://www.seeker.com/earth/animals/ancient-skull-shows-what-the-last-common-ancestor-of-apes-and-humans-looked-like


--------------------------------


Chew on this: we finally know how our jaws evolved

October 20, 2016

https://theconversation.com/chew-on-this-we-finally-know-how-our-jaws-evolved-64559


--------------------------------


Transitional Fossils of Hominid Skulls

2012

http://www.theistic-evolution.com/transitional.html


--------------------------------


The evolution of earthworms


http://blogs.biomedcentral.com/bmcseriesblog/2017/06/01/the-evolution-of-earthworms/


-----------------------------------------------



Worm Genomes Reveal The Path Of Evolution

Scientists in Japan have gained new insights into the genetic similarities between distantly related animal groups by analyzing the genomes of two species of worms.




 https://www.asianscientist.com/2017/12/in-the-lab/worm-genome-vertebrate-evolution/



-----------------------------------------------



Ancient worms may have saved Earth

2014

https://www.sciencemag.org/news/2014/08/ancient-worms-may-have-saved-earth


-----------------------------------------------



Strange Worms Are Taking Their Place on Your Family Tree

2016

The Cambrian explosion of animal life now seems more like a whimper.

http://nautil.us/issue/34/adaptation/strange-worms-are-taking-their-place-on-your-family-tree

 


-----------------------------------------------


Evolution of development in nematodes related to C. elegans



Abstract

The knowledge about C. elegans provides a paradigm for comparative studies. Nematodes are very attractive in evolutionary developmental biology given the species richness of the phylum and the easiness with which several of these species can be cultured under laboratory conditions. Embryonic, gonad, vulva and male tail development were studied and compared in nematodes of five different families, providing a detailed picture of evolutionary changes in development. In particular, vulva development has been studied in great detail and substantial differences in the cellular, genetic and molecular mechanisms have been observed between C. elegans and other nematodes. For example, vulva induction relies on the single anchor cell in C. elegans, whereas a variety of different cellular mechanisms are used in related species. In recent years, a few species have been developed as satellite systems for detailed genetic and molecular studies, such as Oscheius tipulae and Pristionchus pacificus.

http://www.wormbook.org/chapters/www_evoldevnematode/evoldevnematode.html


-----------------------------------------------


This Worm That Lost Its Legs Is The Earliest Known Example of Evolutionary Reversion

28 FEBRUARY 2020





https://www.sciencealert.com/this-worm-that-lost-its-legs-is-the-earliest-known-example-of-evolutionary-reversion



----------------------------------------------



Tiny worm burrows may reveal when first complex animals evolved

11 September 2017

https://www.newscientist.com/article/2146935-tiny-worm-burrows-may-reveal-when-first-complex-animals-evolved/



-----------------------------------------------




An Amphisbaenian Skull from the European Miocene and the Evolution of Mediterranean Worm Lizards

2014

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098082



-----------------------------------------------



Conserved evolution of skull shape in Caribbean headfirst burrowing worm lizards (Squamata: Amphisbaenia)

2018

https://www.researchgate.net/publication/329017535_Conserved_evolution_of_skull_shape_in_Caribbean_headfirst_burrowing_worm_lizards_Squamata_Amphisbaenia



-----------------------------------------------



Fish finger fossils show the beginnings of hands

March 18, 2020

https://www.cnn.com/2020/03/18/world/fish-finger-fossil-scn/index.html



-----------------------------------------------

 



 Synchrotron X-ray absorption spectroscopy of melanosomes in vertebrates and cephalopods: implications for the affinity of Tullimonstrum

2019


Was Tully a spineless monster?

 

 

 








The chemical compositions of fossilized eyes could bring us closer to solving the mystery of a bizarre extinct beast.

Approximately 300-million-year-old fossils of Tullimonstrum, or ‘Tully Monster’, reveal a bizarre slug-like aquatic creature with a long, clawed appendage where its mouth should be. Whether Tully was a vertebrate, like mammals and reptiles, or an invertebrate, like crustaceans and octopuses, is still debated.

A team led by researchers from University College Cork used a particle accelerator to compare the chemical properties of eye melanosomes — cell structures containing the ultraviolet-screening pigment melanin — in modern and fossil vertebrates and invertebrates, from sea bass to squid.

They found that across both existing and fossilised species, vertebrate eye melanosomes contained a higher ratio of zinc to copper than those of invertebrates. As for Tully, this ratio was closer to that of invertebrates.

Studying melanosome chemistry in many more invertebrates could help narrow down what type of animal Tully actually was.


https://www.natureindex.com/article/10.1098/rspb.2019.1649



----------------------------------------------



Details of Evolutionary Transition from Fish to Land Animals Revealed

https://www.nsf.gov/news/news_summ.jsp?cntn_id=112416



---------------------------------------------



Ancient shark fossil reveals new insights into jaw evolution

April 16, 2014

Summary:

    The skull of a newly discovered 325-million-year-old shark-like species suggests that early cartilaginous and bony fishes have more to tell us about the early evolution of jawed vertebrates -- including humans -- than do modern sharks, as was previously thought. The new study shows that living sharks are actually quite advanced in evolutionary terms, despite having retained their basic 'sharkiness' over millions of years.



 "Sharks are traditionally thought to be one of the most primitive surviving jawed vertebrates. And most textbooks in schools today say that the internal jaw structures of modern sharks should look very similar to those in primitive shark-like fishes," said Alan Pradel, a postdoctoral researcher at the Museum and the lead author of the study. "But we've found that's not the case. The modern shark condition is very specialized, very derived, and not primitive."

The new study is based on an extremely well-preserved shark fossil collected by Ohio University professors Royal Mapes and Gene Mapes in Arkansas, where an ocean basin once was home to a diverse marine ecosystem. The fossilized skull of the new species, named Ozarcus mapesae, along with similar specimens from the same location, were part of a recent donation of 540,000 fossils from Ohio University to the Museum.



 








The heads of all fishes -- sharks included -- are segmented into the jaws and a series of arches that support the jaw and the gills. These arches are thought to have given rise to jaws early in the tree of life.

Because shark skeletons are made of cartilage, not bone, their fossils are very fragile and are usually found in flattened fragments, making it impossible to study the shape of these internal structures. But the Ozarcus mapesae specimen was preserved in a nearly three-dimensional state, giving researchers a rare glimpse at the organization of the arches in a prehistoric animal.

"This beautiful fossil offers one of the first complete looks at all of the gill arches and associated structures in an early shark. There are other shark fossils like this in existence, but this is the oldest one in which you can see everything," said John Maisey, a curator in the Museum's Division of Paleontology and one of the authors on the study. "There's enough depth in this fossil to allow us to scan it and digitally dissect out the cartilage skeleton."

https://www.sciencedaily.com/releases/2014/04/140416133336.htm



-----------------------------------------------



 Indonesia’s First Record of ‘Living Fossil’: The Goblin Shark

Aug 2, 2019

https://medium.com/wcs-marine-conservation-program/indonesias-first-record-of-living-fossil-the-goblin-shark-38a9a666142a



----------------------------------------------------------



The goblin shark's slingshot jaws are the fastest of any shark species


August 20 2016

https://www.earthtouchnews.com/natural-world/how-it-works/the-goblin-sharks-slingshot-jaws-are-the-fastest-of-any-shark-species/



----------------------------------------------------------



Morphology and evolution of the jaw suspension in lamniform sharks

July 2005

https://www.researchgate.net/publication/7859850_Morphology_and_evolution_of_the_jaw_suspension_in_lamniform_sharks



----------------------------------------------



Prehistoric ghost shark Helicoprion's spiral-toothed jaw explained

2013

https://blogs.scientificamerican.com/running-ponies/prehistoric-ghost-shark-helicoprions-spiral-toothed-jaw-explained/



----------------------------------------------



Jaw-inspiring: Ancient fish was pivotal in evolution of face, researchers find

https://www.reuters.com/article/us-science-fish/jaw-inspiring-ancient-fish-was-pivotal-in-evolution-of-face-researchers-find-idUSBREA1B22Q20140213



----------------------------------------------




Independently evolved upper jaw protrusion mechanisms show convergent hydrodynamic function in teleost fishes

https://jeb.biologists.org/content/215/9/1456

 



-----------------------------------------------



Buzzsaw-toothed leviathans cruised the ancient seas

http://www.eartharchives.org/articles/buzzsaw-toothed-leviathans-cruised-the-ancient-seas/



----------------------------------------------------------



Shark like Helicoprion Ruled Its Environs with a Row of Vertical Teeth

October 1, 2017

https://www.scientificamerican.com/article/sharklike-helicoprion-ruled-its-environs-with-a-row-of-vertical-teeth/



---------------------------------------------------------



Hammerhead shark study shows cascade of evolution affected size, head shape

May 18, 2010

https://phys.org/news/2010-05-hammerhead-shark-cascade-evolution-affected.html



---------------------------------------------------------



Why the hammerhead shark got its hammer

27 November 2009

https://www.newscientist.com/article/dn18210-why-the-hammerhead-shark-got-its-hammer/



---------------------------------------------------------



This X-ray of a hammerhead shark is both awesome and terrifying

21 September 2018



 



https://www.shortlist.com/news/hammer-head-shark-x-ray


---------------------------------------------------------



Why hammerhead sharks have such funny heads

August 12, 2012

Of all the beautifully odd creatures, the hammerhead shark boasts perhaps the strangest of all cephalic physiques.

https://www.mnn.com/earth-matters/animals/stories/why-hammerhead-sharks-have-such-funny-heads



---------------------------------------------------------



Evolution of the hammerhead cephalofoil: Shape change, space utilization, and feeding biomechanics in hammerhead sharks (Sphyrnidae)

2010

https://www.semanticscholar.org/paper/Evolution-of-the-hammerhead-cephalofoil%3A-Shape-and-Mara/6285de12ec8c7bdf97b37867c585ed870c1678f7



---------------------------------------------------------



Sphyrna mokarran, Great Hammerhead

http://digimorph.org/specimens/Sphyrna_mokarran/

 


---------------------------------------------------------


New ancient shark species gives insight into origin of great white

November 4, 2012

https://www.floridamuseum.ufl.edu/science/new-ancient-shark-species-gives-insight-into-origin-of-great-white/



---------------------------------------------------------



Preserved shark fossil adds evidence to great white’s origins


August 1, 2009

https://www.floridamuseum.ufl.edu/science/preserved-shark-fossil-adds-evidence-to-great-whites-origins/



---------------------------------------------------------



Great white sharks older than previously thought, study says

https://www.foxnews.com/science/mediterranean-great-white-sharks-older-than-thought



---------------------------------------------------------



Teeth help scientists trace evolution of great white shark family to Middle Jurassic

July 5, 2019

https://www.upi.com/Science_News/2019/07/05/Teeth-help-scientists-trace-evolution-of-great-white-shark-family-to-Middle-Jurassic/2611562342470/



---------------------------------------------------------



A 300 Million Year Old Shark Skull Was Discovered Inside Kentucky Cave

https://www.discovery.com/nature/300-million-year-old-shark-skull-found-buried-inside-mammoth-cav



---------------------------------------------------------



Development and evolution of tooth renewal in neoselachian sharks as a model for transformation in chondrichthyan dentitions

05 March 2018

https://onlinelibrary.wiley.com/doi/full/10.1111/joa.12796




---------------------------------------------------------




The genome of the great white shark shows how it uniquely evolved to be a survivor

February 20, 2019

https://qz.com/1554190/great-white-sharks-massive-genomes-may-help-humans-fight-cancer/



---------------------------------------------------------



How the Great White Shark's genes may help to fight cancer

21 Feb 2019

https://www.weforum.org/agenda/2019/02/scientists-just-mapped-the-great-white-sharks-genome-revealing-clues-that-may-help-us-heal-wounds-and-fight-cancer/




--------------------------------------------------------



 Problems in Fish-to-Tetrapod Transition: Genetic Expeditions Into Old Specimens

16 July 2018

https://www.frontiersin.org/articles/10.3389/fcell.2018.00070/full




-------------------------------------------------------



8 - Origin, Development and Evolution of the Fish Skull

December 2018

https://www.cambridge.org/core/books/evolution-and-development-of-fishes/origin-development-and-evolution-of-the-fish-skull/3592B378983E67F5A3F011F8C5EEBFE1


-----------------------------------------------------------
-----------------------------------------------------------



Evolutionary history of anglerfishes (Teleostei: Lophiiformes): A mitogenomic perspective

February 2010

https://www.researchgate.net/publication/41547721_Evolutionary_history_of_anglerfishes_Teleostei_Lophiiformes_A_mitogenomic_perspective

 


----------------------------------------------------------


Bait and Switch: A Trick Used by Both Anglerfish and Evolutionists

DECEMBER 29, 2011

https://www.icr.org/article/bait-switch-trick-used-by-both-anglerfish


----------------------------------------------------------


Anglerfish and their headlamp bacteria have a crazy relationship

July 19th, 2018

https://www.futurity.org/anglerfish-bacteria-symbiosis-1816222/


----------------------------------------------------------


How (and why) fins turn into limbs: insights from anglerfish

March 2019

https://www.cambridge.org/core/journals/earth-and-environmental-science-transactions-of-royal-society-of-edinburgh/article/how-and-why-fins-turn-into-limbs-insights-from-anglerfish/7D43B7251465600BCC40B23E51D6FBF9


----------------------------------------------------------


Evolutionary history of anglerfishes (Teleostei: Lophiiformes): a mitogenomic perspective

23 February 2010

https://bmcevolbiol.biomedcentral.com/articles/10.1186/1471-2148-10-58


----------------------------------------------------------


Glowing bacteria on deep-sea fish shed light on evolution, 'third type' of symbiosis

July 18, 2018

https://phys.org/news/2018-07-bacteria-deep-sea-fish-evolution-symbiosis.html



---------------------------------------------------------



Researchers have traced the evolution of glowing shrimp

February 10, 2015





(Composite showing secretory luminescence as a defensive mechanism).

https://phys.org/news/2015-02-evolution-shrimp.html



---------------------------------------------------------



Mantis shrimp shoulder their evolutionary baggage and bluff

https://evolution.berkeley.edu/evolibrary/article/mantisshrimp_01

 


----------------------------------------------------------



Insect-like brain region found in crustacean group

October 2017

‘Mushroom bodies’ associated with learning were thought to be exclusive to insects.

https://www.nature.com/articles/d41586-017-04098-6



-----------------------------------------------------------



New Fossil Fills Gap in Evolution of Comma Shrimps

Dec 5, 2019

http://www.sci-news.com/paleontology/eobodotria-muisca-07876.html



----------------------------------------------------------



'Perplexing' New Crab Species Sheds Light on Crustacean Evolution

2019

https://www.discovermagazine.com/planet-earth/perplexing-new-crab-species-sheds-light-on-crustacean-evolution



----------------------------------------------------------



Analyzing fish skull development and evolutionary success

March 30, 2018

https://news.wsu.edu/2018/03/30/analyzing-fish-skull-development-evolutionary-success/



-------------------------------------------------------



Fish fossil suggests our skeleton evolved face first

25 September 2013

https://www.newscientist.com/article/dn24268-fish-fossil-suggests-our-skeleton-evolved-face-first/



------------------------------------------------



Form and function of damselfish skulls: rapid and repeated evolution into a limited number of trophic niches

2009

https://bmcevolbiol.biomedcentral.com/articles/10.1186/1471-2148-9-24



-----------------------------------------------



Scientists finally figure out evolution of bizarre ‘bristle-jaw’ worm

2019





Chaetognaths, or arrow worms, have a distinct jaw structure composed of a dense protein matrix and a fibrous substance called chitin

https://www.siliconrepublic.com/innovation/bizarre-bristle-jaw-worm-evolution



-----------------------------------------------



For bone-eating worms, smaller is better

2015

https://www.nature.com/scitable/blog/accumulating-glitches/for_boneeating_worms_smaller_is/



-----------------------------------------------



Tyrannobdella rex N. Gen. N. Sp. and the Evolutionary Origins of Mucosal Leech Infestations

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010057

Abstract

Background

Leeches have gained a fearsome reputation by feeding externally on blood, often from human hosts. Orificial hirudiniasis is a condition in which a leech enters a body orifice, most often the nasopharyngeal region, but there are many cases of leeches infesting the eyes, urethra, vagina, or rectum. Several leech species particularly in Africa and Asia are well-known for their propensity to afflict humans. Because there has not previously been any data suggesting a close relationship for such geographically disparate species, this unnerving tendency to be invasive has been regarded only as a loathsome oddity and not a unifying character for a group of related organisms.



------------------------------------------------



New fossil trove documents recovery of life on Earth after dinosaur-killing asteroid impact

October 24, 2019

https://www.washington.edu/news/2019/10/24/fossil-mammals-denver-basin/




---------------------------------


Scientists made a chicken more like a dinosaur to see how beaks evolved

2015

https://www.theverge.com/2015/5/13/8600421/dino-chicken-studying-bird-beak-evolution


--------------------------------


Psittacosaurus Dinosaur Skull Study Reveals Three Species Are Actually One

Aug 14, 2013

https://www.huffpost.com/entry/psittacosaurus-dinosaur-skull-study-species_n_3745347


--------------------------------




Tyrannosaurus rex (T. rex) evolved from tiny dinosaurs, fossils show

https://www.dw.com/en/tyrannosaurus-rex-t-rex-evolved-from-tiny-dinosaurs-fossils-show/a-48625940



---------------------------------


 In Analysis of Skulls, Following the Path From T. Rex to Falcon

2012

https://www.nytimes.com/2012/06/05/science/skull-analysis-charts-the-changes-from-dinosaurs-to-birds.html


----------------------------------



Take a T-Rex and a chicken and you’ll see how dinosaurs shrank, survived and evolved into birds

July 31, 2014

https://theconversation.com/take-a-t-rex-and-a-chicken-and-youll-see-how-dinosaurs-shrank-survived-and-evolved-into-birds-29996



-------------------------------------------------------



11 times birds looked like the dinosaurs they secretly are

11 Feb 2016

https://www.sbs.com.au/topics/science/nature/article/2016/02/11/11-times-birds-looked-dinosaurs-they-secretly-are



-------------------------------------------------------



Haast’s Eagle Was Big & Strong Enough to Prey on Humans

December 21, 2012








https://scitechdaily.com/haasts-eagle-was-big-strong-enough-to-prey-on-humans/



-------------------------------------------------------



A Fascinating Example for Convergent Evolution: Endangered Vultures

2014

https://www.hilarispublisher.com/open-access/a-fascinating-example-for-convergent-evolution-endangered-vultures-2332-2543-1-132.pdf



-------------------------------------------------------



Evolutionary history of New and Old WOrld vulture inferred from nucleotide sequences of mitochondrial cytochrome b Gene


https://www.jstor.org/stable/56332?seq=1



------------------------------------------------------



Amazing Species: The Great (and Gross) Turkey Vulture

Recognizing an underappreciated evolutionary marvel

March 15, 2017

https://www.cmnh.org/the-great-(and-gross)-turkey-vulture



------------------------------------------------------



A Morphometric Study on the Skull of the Turkeys (Meleagris gallopavo)


2018

https://dergipark.org.tr/tr/download/article-file/499933



------------------------------------------------------



The phylogenetic significance of the morphology of the syrinx, hyoid and larynx, of the southern cassowary, Casuarius casuarius (Aves, Palaeognathae)

2019

https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-019-1544-7



------------------------------------------------------



Meet a Living Dinosaur: The Giant Cassowary

https://everwideningcircles.com/2016/12/28/meet-living-dinosaur-giant-cassowary/



------------------------------------------------------



Well-preserved fossils show ostrich relatives lived in North America 50 million years ago

July 5, 2016

https://vtnews.vt.edu/articles/2016/07/science-ostrichrelativenew.html



------------------------------------------------------



This Newly-Discovered Dinosaur Looks Just Like a Modern Day Cassowary

7/27/17

https://gizmodo.com/this-newly-discovered-dinosaur-looks-just-like-a-modern-1797274767

 


------------------------------------------------------



Bony Pits in the Ostrich (Struthio camelus) and Emu (Dromaius novaehollandiae) Bill Tip

14 March 2017

https://anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/ar.23594

 


------------------------------------------------------


Mechanical Analysis of Feeding Behavior in the Extinct “Terror Bird” Andalgalornis steulleti (Gruiformes: Phorusrhacidae)

August 18, 2010

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011856



------------------------------------------------------


Fowl-mouthed study finds that diet shaped duck, goose beaks

May 30, 2017


An analysis of the relationship between diet and beak shape among waterfowl not only shows that feeding is likely the major influence that fits the bill, but also suggests that early birds of the order were likely more duck-like than goose-like.

https://www.brown.edu/news/2017-05-30/beaks



------------------------------------------------------



Correlated evolution of neck length and leg length in birds

08 May 2019

https://royalsocietypublishing.org/doi/10.1098/rsos.181588



------------------------------------------------------



The skull roof tracks the brain during the evolution and development of reptiles including birds

2017

http://www.danieljfield.com/Home/Publications_files/Fabbri%20et%20al%202017.%20The%20skull%20roof%20tracks%20the%20brain%20during%20the%20evolution%20and%20development%20of%20reptiles%20including%20birds.pdf



------------------------------------------------------




Chickens Have Been Modified to Lay Eggs Containing Anti-Cancer Medicine

29 JANUARY 2019

https://www.sciencealert.com/genetically-modified-chickens-are-laying-eggs-containing-anti-cancer-drugs




-----------------------------------------------------



"Chicken bioreactors" lay medicinal eggs

January 28, 2019

https://newatlas.com/genetically-modified-hens-proteins-eggs/58228/



------------------------------------------------------



US government approves transgenic chicken

09 December 2015

The eggs of the genetically engineered animal contain an enzyme that can treat a rare disease.


https://www.nature.com/news/us-government-approves-transgenic-chicken-1.18985


------------------------------------------------------



Scientists Created a Dino-Skulled Chicken to Explore Evolution

May 14, 2015

https://www.pbs.org/wgbh/nova/article/scientists-created-a-dino-skulled-chicken-to-explore-evolution/


-----------------------------------------------------



Chicken Grows Face of a Dinosaur

13 May 2015

A chicken embryo with a dinosaur-like snout instead of a beak has been developed by scientists

http://www.bbc.com/earth/story/20150512-bird-grows-face-of-dinosaur



-----------------------------------------------------



Tracking Transition: From dinosaurs to birds, brain-skull evolution

January 28, 2018

http://www.yalescientific.org/2018/01/tracking-transition-from-dinosaurs-to-birds-brain-skull-evolution/


------------------------------------------------------



What Drives Bird Vision? Bill Control and Predator Detection Overshadow Flight

07 November 2017

https://www.frontiersin.org/articles/10.3389/fnins.2017.00619/full




-----------------------------------------------------



 One Of The Last Surviving Raptors Has Been Uncovered In New Mexico

Dineobellator notohesperus

https://www.iflscience.com/plants-and-animals/one-of-the-last-surviving-raptors-has-been-uncovered-in-new-mexico/



----------------------------------------------------


Fossil of new feathered raptor called 'dancing dragon' found in China bridges evolution gap between dinosaurs and birds

 17 January 2020

    A new fossil discovered in China sheds light on dinosaurs evolution into birds
    The 'Dancing dragon' fossil is named for its active looking pose
    It was a crow-sized relative of the velociraptor with unique plumage
    Scientists say its feathers may help illuminate dinosaurs 'transition into birds

https://www.dailymail.co.uk/sciencetech/article-7901027/Dancing-dragon-shows-feathers-grew-differently-dinosaurs-birds.html


-----------------------------------------------------


A Triassic averostran-line theropod from Switzerland and the early evolution of dinosaurs

2019

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669044/


----------------------------------------------------


Paleontologists discover complete Saurornitholestes langstoni specimen

October 17, 2019

Discovery provides valuable insight into evolution of theropod dinosaurs around the world

https://www.sciencedaily.com/releases/2019/10/191017125237.htm


----------------------------------------------------


Halszkaraptor escuilliei and the evolution of the paravian bauplan


11 November 2019

https://www.nature.com/articles/s41598-019-52867-2


---------------------------------------------------


Discovery of Raptor-Like Dinosaur Adds a New Wrinkle to the Origin of Birds

July 10, 2019

A small, 150 million-year-old dinosaur unearthed in Wyoming ran on the ground, but it may have been closely related to some of the first fliers

https://www.smithsonianmag.com/science-nature/discovery-raptor-dinosaur-adds-new-wrinkle-origin-birds-180972588/


----------------------------------------------------


Vicious Velociraptor : tales of a turkey-sized dinosaur

8 August 2018

https://www.nhm.ac.uk/discover/velociraptor-facts.html


----------------------------------------------------


Evolution of the vomer and its implications for cranial kinesis in Paraves

September 24, 2019

https://www.pnas.org/content/116/39/19571


-----------------------------------------------------



Meet Lori, A Tiny Dinosaur That May Help Explain How Birds Evolved Flight

10 July 2019

The chicken-size carnivore from the late Jurassic is already ruffling feathers among palaeontologists.

https://www.nationalgeographic.com.au/science/meet-lori-a-tiny-dinosaur-that-may-help-explain-how-birds-evolved-flight.aspx




-----------------------------------------------------



Built To Fly

With its four wings and a long, bony tail, Microraptor was unlike any bird alive today. This is because it was a dinosaur—one that evolved long after the first known bird, Archaeopteryx, split off from the dinosaur family tree. Earlier dinosaurs, common ancestors to both Microraptor and Archaeopteryx, had already formed many of the physiological traits needed for getting airborne, such as feathers and light, hollow bones. With these structures in place, both animals were able to separately take further evolutionary steps by forming wings on their arms (and in Microraptor, legs) and getting off the ground. Below, learn more about the evolution of gliding and flight, and of birds, by comparing the skeletons of Archaeopteryx, Microraptor, and Deinonychus, one of Microraptor's closest non-flying relatives.—Rima Chaddha

https://www.pbs.org/wgbh/nova/microraptor/skel-nf.html


-----------------------------------------------------



How to Make a Bird Skull: Major Transitions in the Evolution of the Avian Cranium, Paedomorphosis, and the Beak as a Surrogate Hand

 01 July 2016

https://academic.oup.com/icb/article/56/3/389/2363364




-----------------------------------------------------



Dinosaur Discovery Sheds New Light On How Raptors Evolved

October 12, 2019

https://paleontologyworld.com/dinosaurs-%E2%80%93-species-encycolpedia-paleontologists-curiosities/dinosaur-discovery-sheds-new-light-how


-----------------------------------------------------


Cranial functional morphology of Archaeopteryx and the biomechanical triggers of avian evolution

https://gtr.ukri.org/project/A062AC30-6AFA-4374-B67B-F2ADC6E16083


-----------------------------------------------------


Analysis of skull morphometric characters in Owls (Strigiformes)

2018

https://content.sciendo.com/downloadpdf/journals/orhu/26/1/article-p41.xml


-----------------------------------------------------


Craniofacial diversification in the domestic pigeon and the evolution of the avian skull.

12 Mar 2017

https://europepmc.org/article/med/28812673


-----------------------------------------------------


The shapes of bird beaks are highly controlled by nondietary factors

May 10, 2016

https://www.pnas.org/content/113/19/5352


-----------------------------------------------------


Birds of prey constrained in the beak evolution race

April 26, 2016

https://phys.org/news/2016-04-birds-prey-constrained-beak-evolution.html


-----------------------------------------------------



Why raptors are losing the race in beak evolution

May 7, 2016

http://www.biosphereonline.com/2016/05/07/raptors-losing-race-beak-evolution/



-----------------------------------------------------


Unlike Darwin's Finches, Raptor Beaks Come In One Shape


https://www.iflscience.com/plants-and-animals/unlike-darwins-finches-raptor-beaks-come-limited-shapes/

-----------------------------------------------------


How the development of skulls and beaks made Darwin's finches one of the most diverse species

February 3, 2020

https://www.sciencedaily.com/releases/2020/02/200203141441.htm


-----------------------------------------------------


Analysis of skull morphometric characters in diurnal raptors (Accipitriformes and Falconiformes)

27 Jul 2019

https://content.sciendo.com/view/journals/orhu/27/1/article-p117.xml


--------------------------------------------------------



Wonderchicken fossil casts new light on bird evolution

March 24, 2020

The oldest known bird fossil, from the age of dinosaurs, has skull features similar to modern chickens. The scientists who found it have nicknamed it “Wonderchicken.” It’s providing valuable insights into the evolution of birds.

https://earthsky.org/earth/wonderchicken-oldest-fossil-modern-bird


-----------------------------------------------------


Unique skull network complexity of Tyrannosaurus rex among land vertebrates

06 February 2019

https://www.nature.com/articles/s41598-018-37976-8


-----------------------------------------------------


Development and evolution of the tetrapod skull–neck boundary

07 January 2020

https://onlinelibrary.wiley.com/doi/full/10.1111/brv.12578


----------------------------------------------------


Homology of the cranial vault in birds: New insights based on embryonic fate-mapping and character analysis

Aug 2016

https://www.researchgate.net/figure/Alternative-hypothesis-for-the-evolution-of-the-cranial-vault-in-birds-and-other_fig2_306032520


-----------------------------------------------------


Sexing of chicken eggs by fluorescence and Raman spectroscopy through the shell membrane

February 23, 2018

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192554


-----------------------------------------------------



Morphological variation under domestication: how variable are chickens?


08 August 2018

https://royalsocietypublishing.org/doi/10.1098/rsos.180993



------------------------------------------------------



How Dinosaurs Shrank and Became Birds

June 12, 2015

Modern birds appeared to emerge in a snap of evolutionary time. But new research illuminates the long series of evolutionary changes that made the transformation possible

https://www.scientificamerican.com/article/how-dinosaurs-shrank-and-became-birds/



-----------------------------------------------------


Evolutionary History of the Chicken (pigeon, and other birds) + Domestication

1 May, 2013

https://blogs.lt.vt.edu/chickens/2013/05/01/evolutionary-history-of-the-chicken-pigeon-and-other-birds/


-----------------------------------------------------


Can Scientists Turn Birds Back Into Dinosaur Ancestors?

https://carlzimmer.com/can-scientists-turn-birds-back-into-dinosaur-ancestors/


-----------------------------------------------------



Curious Kids: how can chickens run around after their heads have been chopped off?

September 25, 2018

https://theconversation.com/curious-kids-how-can-chickens-run-around-after-their-heads-have-been-chopped-off-103701


-----------------------------------------------------


A comparative analysis of the avian skull: Woodpeckers and chickens

2018

http://meyersgroup.ucsd.edu/papers/journals/Meyers%20449.pdf


-----------------------------------------------------


A Natural Stress Deflector on the Head? Mechanical and Functional Evaluation of the Woodpecker Skull Bones

29 January 2019

https://onlinelibrary.wiley.com/doi/abs/10.1002/adts.201800152


----------------------------------------------------


Woodpecker Inspires Designers, Knocks Evolution

2011

https://www.icr.org/article/woodpecker-inspires-designers-knocks


----------------------------------------------------


Woodpeckers show signs of possible brain damage, but that might not be a bad thing

February 2, 2018

https://www.sciencedaily.com/releases/2018/02/180202140910.htm


----------------------------------------------------



A Lifetime of Hammering Trees Might Affect Woodpecker Brains After All

February 09, 2018

A new study into the woodpecker brain shows proteins linked to CTE in football players, but it’s unclear whether birds suffer the same fate

https://www.audubon.org/news/a-lifetime-hammering-trees-might-affect-woodpecker-brains-after-all


-----------------------------------------------------


Effect of Microstructure of Spongy Bone in Different Parts of Woodpecker’s Skull on Resistance to Impact Injury

2013

https://www.hindawi.com/journals/jnm/2013/924564/


----------------------------------------------------


The skull of the golden-fronted woodpecker protects it from brain injury by absorbing shock via a plate-like spongey bone in the frontal cranium.

October 22, 2016








https://asknature.org/strategy/skull-protects-brain-from-impact/


-----------------------------------------------------


Anatomy and Evolution of the Woodpecker's Tongue

2003

http://www.talkorigins.org/faqs/woodpecker/woodpecker.html



-----------------------------------------------------



Structural analysis of the tongue and hyoid apparatus in a woodpecker


2017

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063634/




-----------------------------------------------------



The respiratory system of birds facilitates efficient exchange of carbon dioxide and oxygen via continuous unidirectional airflow and air sacs

March 24, 2020

https://asknature.org/strategy/respiratory-system-facilitates-efficient-gas-exchange/#.XohxYXJOnQw



----------------------------------------------------



Bird, meet cousin alligator

November 4, 2010

https://news.harvard.edu/gazette/story/2010/11/bird-meet-cousin-alligator/



----------------------------------------------------


Six million-year-old bird skeleton points to arid past of Tibetan plateau

April 2, 2020

https://phys.org/news/2020-04-million-year-old-bird-skeleton-arid-tibetan.html


-----------------------------------------------------


What Makes Owls So Different From Other Bird Species?

May 2, 2017

https://www.forbes.com/sites/quora/2017/05/02/what-makes-owls-so-different-from-other-bird-species/#27bc8763707c


-----------------------------------------------------



Scientists track the brain-skull transition from dinosaurs to birds

2017

https://news.yale.edu/2017/09/11/scientists-track-brain-skull-transition-dinosaurs-birds




---------------------------------




How Do We Know Humans Are Primates?

Besides similar anatomy and behavior, there is DNA evidence. It confirms that humans are primates and that modern humans and chimpanzees diverged from a common ancestor between 8 and 6 million years ago. There is only about a 1.2 percent genetic difference between modern humans and chimpanzees throughout much of their genetic code.

http://humanorigins.si.edu/education/how-do-we-know/how-do-we-know-humans-are-primates



------------------------------------


Researchers hope newly excavated dino skull answers evolutionary questions

September 29, 2017

https://www.ctvnews.ca/sci-tech/researchers-hope-newly-excavated-dino-skull-answers-evolutionary-questions-1.3612207


------------------------------------


What dinosaur and bird skulls tell us about brains

2017

https://www.futurity.org/dinosaur-bird-shift-skulls-1540352/


-----------------------------------



Big dinosaurs kept cool thanks to blood vessel clusters in their heads


October 16, 2019

https://www.sciencenews.org/article/dinosaurs-thermoregulation-blood-vessels-head




-----------------------------------


X-ray images of 74-million-year-old ‘Bisti Beast’ dinosaur skull reveal how ‘bone crushing adaptations’ arose in the T. rex family

2017

    The skull of 'Bisti Beast' belonged to a relative of the Tyrannosaurus rex
    A scan of the skull revealed that it had big-headed, bone crushing adaptations
    The scan was the highest-resolution scan of a tyrannosaur skull ever done
    This revealed presense of un-erupted teeth, the brain cavity, sinus cavities

https://www.dailymail.co.uk/sciencetech/article-4793782/X-ray-dinosaur-skull-gives-insight-T-rex-evolution.html


----------------------------------



New tyrannosaur from the mid-Cretaceous of Uzbekistan clarifies evolution of giant body sizes and advanced senses in tyrant dinosaurs

2016

Tyrannosaurs—the iconic group of dinosaurian carnivores that includes Tyrannosaurus rex—dominated latest Cretaceous ecosystems with their colossal sizes and sophisticated senses. A gap in the mid-Cretaceous fossil record between these giant apex predators and their older, smaller relatives makes it difficult to understand how the characteristic body size and ecological habits of T. rex and kin developed. A new species from Uzbekistan fills this gap. This horse-sized animal shows that tyrannosaurs had yet to achieve huge size at this time but had already evolved key brain and sensory features of the gigantic latest Cretaceous species. Tyrannosaurs apparently developed giant body size rapidly, late in the Cretaceous, and their success may have been enabled by their early-evolving keen senses.

https://www.pnas.org/content/early/2016/03/08/1600140113



----------------------------------



Unique imaging of a dinosaur's skull tells evolutionary tale

August 15, 2017

Collaboration creates highest-resolution scan of a large tyrannosaur skull

https://www.sciencedaily.com/releases/2017/08/170815095038.htm




----------------------------------



Tyrannosaurus Rex's Bite Was so Powerful It Should Have Shattered the Dinosaur's Own Skull. Here's Why It Didn't

9/25/19

https://www.newsweek.com/tyrannosaurus-rex-bite-powerful-dinosaur-skull-1461253




-----------------------------------



Sensitive T. rex? This new dino might change the face of tyrannosaurs, evolution

March 30, 2017

https://www.csmonitor.com/Science/2017/0330/Sensitive-T.-rex-This-new-dino-might-change-the-face-of-tyrannosaurs-evolution



----------------------------------



Radioactive dinosaur skull helped researchers make new discovery

February 4, 2020

https://www.cnn.com/2020/01/24/world/new-allosaurus-dinosaur-fossil-scn/index.html




----------------------------------



Aquatic adaptation in the skull of carnivorous dinosaurs (Theropoda: Spinosauridae) and the evolution of aquatic habits in spinosaurids

January 2019

https://www.sciencedirect.com/science/article/pii/S0195667117303427

 


----------------------------------



Birds' unique skulls linked to young dinosaur brains

2017

https://www.imperial.ac.uk/news/181581/birds-unique-skulls-linked-young-dinosaur/



---------------------------------



The skull evolution of oviraptorosaurian dinosaurs: the role of niche partitioning in diversification

November 07, 2019

https://publons.com/publon/10.1111/jeb.13557/



---------------------------------



Craniodental functional evolution in sauropodomorph dinosaurs

August 2017

https://www.cambridge.org/core/journals/paleobiology/article/craniodental-functional-evolution-in-sauropodomorph-dinosaurs/36E27FB35DC8CC3CB68E9377EE43936D



---------------------------------



Dinosaur discovery sheds new light on how raptors evolved

October 11, 2019

Near-complete fossil found in Alberta reveals that North American and Asian raptors had distinct family trees.

https://www.folio.ca/dinosaur-discovery-sheds-new-light-on-how-raptors-evolved/



---------------------------------




Unprecedented Fossil Provides New Understanding of Bird Evolution

2018

https://www.pbs.org/wgbh/nova/article/unprecedented-fossil-provides-new-understanding-of-bird-evolution/



----------------------------------



How humans shaped the evolution of the world’s most common bird

https://www.bbcearth.com/blog/?article=how-humans-shaped-the-evolution-of-the-worlds-most-common-bird



----------------------------------




“Andrew”: The Smallest Diplodocus Skull Ever Discovered Reveals Clues About The Group's Evolution.


October 12, 2018

https://paleontologyworld.com/dinosaurs-%E2%80%93-species-encycolpedia-paleontologists-curiosities/%E2%80%9Candrew%E2%80%9D-smallest-diplodocus-skull-ever



---------------------------------



Fossil of 'first giant' dinosaur discovered in Argentina

10 July 2018

https://www.bbc.com/news/science-environment-44744153



------------------------------------



Biology of the sauropod dinosaurs: the evolution of gigantism

2011

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045712/



-----------------------------------



First complete sauropod dinosaur skull from the Cretaceous of the Americas and the evolution of sauropod dentition

2010

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841758/



-----------------------------------



New Species of Giant Predatory Dinosaur Discovered in Thailand Provides a New Glimpse at Dinosaur Evolution

October 13, 2019

https://scitechdaily.com/new-species-of-giant-predatory-dinosaur-discovered-in-thailand-provides-a-new-glimpse-at-dinosaur-evolution/



--------------------------------------



Skull remains of the dinosaur Saturnalia tupiniquim (Late Triassic, Brazil): With comments on the early evolution of sauropodomorph feeding behaviour

September 6, 2019

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221387



--------------------------------------



Dimetrodon Is Not a Dinosaur: Using Tree Thinking to Understand the Ancient Relatives of Mammals and their Evolution

05 February 2009

https://evolution-outreach.biomedcentral.com/articles/10.1007/s12052-009-0117-4


--------------------------------



Scientists just found soft tissue inside a dinosaur fossil. Here's why that's so exciting.


Jun 9, 2015





The photo above, from a new study published today in Nature Communications and led by Sergio Bertazzo of Imperial College London, shows an extremely zoomed-in view of a 75-million-year-old theropod claw, taken from the London Natural History Museum's collection. When researchers scraped tiny pieces off the fossil and looked at them under an electron microscope, they found tiny structures that look a lot like collagen fibers present in our own ligaments, tendons, and bones.

https://www.vox.com/2015/6/9/8748035/dinosaur-fossil-blood-proteins



--------------------------------



Fish that outlived dinosaurs reveals secrets of ancient skull evolution

Apr 18, 2019

https://www.youtube.com/watch?v=mQrNsA3yxFY



---------------------------------



'Stunning' Fossil Discovery Reveals How Mammals Flourished After The Dinosaurs Died

25 OCTOBER 2019

https://www.sciencealert.com/stunning-fossil-trove-shows-how-mammals-flourished-after-the-dinosaurs-died


---------------------------------



Dinosaur-Era Bird Found With Shockingly Intact Skull

2018

The unprecedented Ichthyornis fossil from Kansas offers fresh perspective on bird evolution.


https://www.nationalgeographic.com/news/2018/05/fossil-bird-skull-3d-dinosaurs-evolution-paleontology-science/


---------------------------------


Dinosaur ossification centres in embryonic birds uncover developmental evolution of the skull

19 November 2018

https://www.nature.com/articles/s41559-018-0713-1/


---------------------------------


The skull evolution of oviraptorosaurian dinosaurs: the role of niche partitioning in diversification

17 October 2019

https://onlinelibrary.wiley.com/doi/abs/10.1111/jeb.13557


---------------------------------

 
Koolasuchus - The Antarctic Amphibian That Ate Dinosaurs

Sep 29, 2019

https://www.youtube.com/watch?v=5-lPDo_KMiA


---------------------------------


The Evolution of Sea Turtles

Oct 6, 2019

https://www.youtube.com/watch?v=h6Zw8A_IYGc


---------------------------------
 

Ecological Correlates and Evolutionary Divergence in the Skull of Turtles: A Geometric Morphometric Assessment

https://www.ncbi.nlm.nih.gov/pubmed/15764561

 
----------------------------------

 

Potentially Oldest Animal Found In 890 Million Year Old Fossil

Aug 18, 2021

https://www.youtube.com/watch?v=_rJJIFDn188

 

----------------------------------


Smallest Known Dinosaur Found in Amber

A bird skull from Myanmar hints at a lost world of tiny fossils that are waiting to be unearthed

March 11, 2020

https://www.scientificamerican.com/article/smallest-known-dinosaur-found-in-amber/


---------------------------------


New Hummingbird-Sized Dinosaur Identified from Skull Trapped in Amber

Fossil shows that miniature dinosaurs likely shared the earth with giants during the Mesozoic Era.

https://www.insidescience.org/news/new-hummingbird-sized-dinosaur-identified-skull-trapped-amber


----------------------------------


 Climbing and Pecking Adaptations in Some North American Woodpeckers

1965

https://www.jstor.org/stable/1365612?seq=1


----------------------------------------------------


Morphological adaptations for relatively larger brains in hummingbird skulls

27 September 2018

https://onlinelibrary.wiley.com/doi/full/10.1002/ece3.4513


-----------------------------------------------------


Some Hummingbirds Evolved Bills That Make Them Better at Fighting—but Worse at Feeding

January 4, 2019

A new study adds complexity to the notion that hummingbirds are ‘all about drinking efficiently from flowers,’ as one researcher puts it


https://www.smithsonianmag.com/smart-news/some-hummingbirds-have-evolved-bills-make-them-better-fightingand-worse-feeding-180971173/


-----------------------------------------------------


Discovery of hummingbird-sized Mesozoic dinosaur reveals new species in bird evolution

March 11, 2020

https://yubanet.com/scitech/discovery-of-hummingbird-sized-mesozoic-dinosaur-reveals-new-species-in-bird-evolution/


-----------------------------------------------------


Hummingbird Evolution Was Fast, but Is Slowing

April 03, 2014

https://www.livescience.com/44593-first-hummingbird-evolutionary-tree.html


-----------------------------------------------------


Hummingbird Evolution Is Booming

 April 3, 2014

The successful, 22 million-year-old group could double in its number of species before leveling off

https://www.scientificamerican.com/article/hummingbird-evolution-is-booming/


-----------------------------------------------------


Endless skulls most beautiful

January 16, 2018






https://www.pnas.org/content/115/3/448


----------------------------------------------------


 Iwaniuk and his unique bird brain collection is central to flight study


January 24, 2011

https://www.uleth.ca/unews/article/iwaniuk-and-his-unique-bird-brain-collection-central-flight-study#.XojT73JOlPY


-----------------------------------------------------



Dinosaur ossification centres in embryonic birds uncover developmental evolution of the skull.

18 Nov 2018

https://europepmc.org/article/med/30455438



-----------------------------------------------------


Dull teeth, long skulls, specialized bites evolved in unrelated plant-eating dinosaurs

December 5, 2019

https://www.sciencedaily.com/releases/2019/12/191205141752.htm


-----------------------------------------------------



The Strange Flying Animals You've Never Heard Of

http://www.bbc.com/earth/story/20150218-flying-animals-you-never-heard-of



---------------------------------


Short Snouts Gave Fruit Bats a Forceful Bite

2011

https://www.livescience.com/17173-bat-skull-evolution-fruit.html


--------------------------------


Correlation of skull morphology and bite force in a bird-eating bat

19 March 2020

https://frontiersinzoology.biomedcentral.com/articles/10.1186/s12983-020-00354-0


--------------------------------


Morphological correlates of bite force and diet in the skull and mandible of phyllostomid bats

29 June 2009

https://besjournals.onlinelibrary.wiley.com/doi/10.1111/j.1365-2435.2009.01549.x


---------------------------------


Form, Function, and Evolution in Skulls and Teeth of Bats

May 1998

https://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1009&context=natrespapers


---------------------------------



No Teeth, Long Tongue, No Problem - Adaptations for Ant-eating

2016

http://thatslifesci.com.s3-website-us-east-1.amazonaws.com/2016-09-05-Adaptations-for-Ant-Eating-AVanderLinden/



-------------------------------



A Fossilized Blood-Engorged Mosquito Is Found For the First Time Ever

October 14, 2013

Testing shows that a 46 million-year-old fossilized mosquito, found by amateur fossil hunters in Montana, contains the blood of an unknown ancient creature

https://www.smithsonianmag.com/science-nature/a-fossilized-blood-engorged-mosquito-is-found-for-the-first-time-ever-1749788/



-------------------------------


The Unique Mosquito That Lives in the Underground

When construction of the London Underground began in the 19th Century, there was an unexpected consequence: evolution

24 March 2016

http://www.bbc.com/earth/story/20160323-the-unique-mosquito-that-lives-in-the-london-underground


-------------------------------




Evolution of Insect Eye Development: First Insights from Fruit Fly, Grasshopper and Flour Beetle


 01 August 2003

https://academic.oup.com/icb/article/43/4/508/617750



-------------------------------



Comes naturally? Using stick insects to study natural selection, predictability of evolution

February 15, 2018

https://phys.org/news/2018-02-naturally-insects-natural-evolution.html



-------------------------------



Chernobyl’s Bugs: The Art And Science Of Life After Nuclear Fallout

April 26, 2014

In 1986, a Swiss artist set out to document insects from regions affected by the Chernobyl disaster, and science is starting to catch up with her

https://www.smithsonianmag.com/arts-culture/chernobyls-bugs-art-and-science-life-after-nuclear-fallout-180951231/



-------------------------------



The Largest Insect Ever Existed Was a Giant 'Dragonfly'

 

2018

http://www.geologyin.com/2018/01/the-largest-insect-ever-existed-was.html



-------------------------------

 

The Giant Fleas which Sucked Dino Blood | Parasitober

Nov 7, 2020

https://www.youtube.com/watch?v=U6jvkecx2s0

 

-------------------------------



54-million-year-old skull reveals early evolution of primate brains

June 22, 2009

The skull belongs to a group of primitive primates known as Plesiadapiforms, which evolved in the 10 million years between the extinction of the dinosaurs and the first traceable ancestors of modern primates. The 1.5-inch-long skull was found fully intact, allowing researchers to make the first virtual mold of a primitive primate brain.

https://www.floridamuseum.ufl.edu/science/54-million-year-old-skull-reveals-early-evolution-of-primate-brains/


-------------------------------



 The Craniofacial Evidence for Anthropoid and Tarsier Relationships

https://link.springer.com/chapter/10.1007/978-1-4757-9197-6_15



------------------------------------



Cousin Achilles: The Little Primate That Could

June 15, 2013

A tiny primate dubbed Archicebus achilles, dated about 55 million years, is taking center stage as the oldest known primate and, at less than an ounce, the smallest.1 Evolutionary paleontologists believe it is the missing link between tarsier-like primates and the anthropoid primate line that includes humans. Xijun Ni, lead author of the paper in Nature, says, “This skeleton will tell us a lot of the story about the origins of primates and about our remote ancestors.”

https://answersingenesis.org/missing-links/cousin-achilles-the-little-primate-that-could/



------------------------------------



Skeletons

https://www.siyavula.com/read/science/grade-10-lifesciences/support-systems-in-animals/06-support-systems-in-animals-02

6.2 Skeletons (ESG82)

The skeleton is the supporting structure of an organism. There are three different types of skeletons: hydrostatic skeletons, endoskeletons and exoskeletons.

    Hydrostatic skeleton: Water exerts pressure on muscular walls, for example, in jellyfish.
    Exoskeleton: The stable chitinous or mineralised outer shell of an organism, for example, the shell of a grasshopper or prawn.
    Endoskeleton: A cartilaginous or mineralized support structure inside the body, for example, in humans and other vertebrates.



-----------------------------------------------



 Evolution of hyperossification expands skull diversity in frogs

March 27, 2020

https://www.pnas.org/content/early/2020/03/26/2000872117

 


------------------------------------


Skulls gone wild: How and why some frogs evolved extreme heads

March 23, 2020

https://phys.org/news/2020-03-skulls-wild-frogs-evolved-extreme.html


-------------------------------------





Frogs have evolved extreme skulls with hidden fangs and horns

March 24, 2020





https://www.cnet.com/news/frogs-have-evolved-extreme-skulls-with-hidden-fangs-and-horns/


------------------------------------


Meet ‘Jaws’, the South American horned frog with a big bite

https://theconversation.com/meet-jaws-the-south-american-horned-frog-with-a-big-bite-80750


------------------------------------


Testing for historical patterns of change: a case study with frog pectoral girdles

1988

https://www.cambridge.org/core/journals/paleobiology/article/testing-for-historical-patterns-of-change-a-case-study-with-frog-pectoral-girdles/38583DCEA4CDEA5B19E5A6BB35AAFE22


------------------------------------


The Palaeozoic Ancestry of Salamanders, Frogs and Caecilians

May 2007

https://www.researchgate.net/publication/213769866_The_Palaeozoic_Ancestry_of_Salamanders_Frogs_and_Caecilians


------------------------------------


The Frog Skeletons vs. Human Skeletons

https://animals.howstuffworks.com/amphibians/frog2.htm


------------------------------------


Jumping in frogs: assessing the design of the skeletal system by anatomically realistic modeling and forward dynamic simulation

2002

https://jeb.biologists.org/content/205/12/1683


------------------------------------


Missing Link Fossil Settles Frog Evolution Debate

2008

https://www.telegraph.co.uk/news/science/science-news/3342595/Missing-link-fossil-settles-frog-evolution-debate.html


------------------------------------


Network architecture associated with the highly specialized hindlimb of frogs

May 17, 2017

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177819


------------------------------------


The complex evolutionary history of the tympanic middle ear in frogs and toads (Anura)

28 September 2016

https://www.nature.com/articles/srep34130


------------------------------------


A striking new genus and species of cave-dwelling frog (Amphibia: Anura: Microhylidae: Asterophryinae) from Thailand

2017

https://peerj.com/articles/4422.pdf


-----------------------------------


Venomous Frogs

http://sciencenetlinks.com/science-news/science-updates/venomous-frogs/


-------------------------------------


 Convergent evolution of chemical defense in poison frogs and arthropod prey between Madagascar and the Neotropics

2005

https://www.pnas.org/content/102/33/11617


-------------------------------------------


The evolution of coloration and toxicity in the poison frog family (Dendrobatidae)

2001

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC33450/



-------------------------------------------


Convergent evolution of chemical defense in poison frogs and arthropod prey between Madagascar and the Neotropics.

2005

https://www.ncbi.nlm.nih.gov/pubmed/16087888

 

-------------------------------------------


Poisonous frogs evolve to sing longer and louder

17 October 2014

https://www.newscientist.com/article/dn26402-poisonous-frogs-evolve-to-sing-longer-and-louder/

 

--------------------------------------------


Morphological comparison of five species of poison dart frogs of the genus Ranitomeya (Anura: Dendrobatidae) including the skeleton, the muscle system and inner organs

February 24, 2017

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0171669


--------------------------------------------


Evolution of Diet Specialization in Poison-Dart Frogs (Dendrobatidae)

1995

https://www.jstor.org/stable/3892588?seq=1

 

--------------------------------------------


The Effect of Miniaturized Body Size on Skeletal Morphology in Frogs

2002

https://www.jstor.org/stable/3061599?seq=1


--------------------------------------------


Skin gland concentrations adapted to different evolutionary pressures in the head and posterior regions of the caecilian Siphonops annulatus

2018

https://www.nature.com/articles/s41598-018-22005-5

Abstract

Amphibian skin is rich in mucous glands and poison glands, secreting substances important for gas exchange and playing a fundamental role in chemical defense against predators and microorganisms. In the caecilian Siphonops annulatus (Mikan, 1920) we observed a concentration of enlarged mucous glands in the head region. In the posterior region of the body a similar concentration is made up of enlarged poison glands. These accumulations of glands structurally resemble the macroglands previously reported in anurans and salamanders. The skin glands in these regions are each surrounded by collagen walls forming a honeycomb-like structure. The collagen network in the head region firmly attaches to tiny pits in the bones of the skull. The two extremities of the body produce different secretions, containing exclusive molecules. Considering the fossorial lifestyle of caecilians, it seems evident that the secretions of the head and caudal region serve different functions. The anterior macrogland of mucous glands, rich in mucous/lipid secretion, in conjunction with the funnel-shaped head, may act to lubricate the body and penetrate the soil, thus facilitating locomotion underground. The blunt posterior end bearing an internalized macrogland of poison glands in the dermis may act in chemical defense and/or by blocking invasion of tunnels.


--------------------------------------------


THE EVOLUTION OF  THE VENOM APPARATUS IN SNAKES FROM  COLUBRIDS TO VIPERIDS & ELAPIDS

1982

https://public.wsu.edu/~kkardong/Web%20of%20KVK_06b/Publications/Evolution_venom_app82.pdf


--------------------------------------------


Viperous fangs: Development and evolution of the venom canal

2008

https://www.sciencedirect.com/science/article/pii/S0925477308000853


--------------------------------------------


Rapid venom evolution in pit vipers may be defensive; Marsupials that prey on venomous snakes also evolve rapidly

2011

https://www.sciencedaily.com/releases/2011/07/110718155618.htm


--------------------------------------------


Snake venom evolved for prey, not protection (Debated)

March 25, 2020

https://phys.org/news/2020-03-snake-venom-evolved-prey.html


--------------------------------------------


Venoms of Rear-Fanged Snakes: New Proteins and Novel Activities

23 July 2019

https://www.frontiersin.org/articles/10.3389/fevo.2019.00279/full


Snake venom research has focused on front-fanged venomous snakes because of the high incidence of human morbidity and mortality from envenomations and larger venom yields of these species, while venoms from rear-fanged snakes have been largely neglected. Rear-fanged snakes (RFS) are a phylogenetically diverse collection of species that feed on a variety of prey and show varying prey capture strategies, from constriction to envenomation. In general, RFS venoms share many toxin families with front-fanged snakes, and venoms generally are either a neurotoxic three-finger toxin (3FTx)-dominated venom or an enzymatic metalloproteinase-dominated venom. These venoms have also been discovered to contain several unique venom protein families. New venom protein superfamilies in RFS venoms include matrix metalloproteinases, distinct from but closely related to snake venom metalloproteinases, veficolins, and acid lipases. Specialized three-finger toxins that target select prey taxa have evolved in some RFS venoms, and this prey capture strategy has appeared in multiple RFS species, from Old World Boiga to New World Spilotes and Oxybelis. Though this same protein superfamily is commonly found in the venoms of elapid (front-fanged) snakes, no elapid 3FTxs appear to show prey-specific toxicity (with the exception of perhaps Micrurus). Neofunctionalization of Spilotes sulphureus 3FTx genes has even resulted in the evolution within a single venom of 3FTxs selectively neurotoxic to different prey taxa (mammals or lizards), allowing this non-constricting RFS to take larger mammalian prey. The large number of 3FTx protein sequences available, together with a growing database of RFS venom 3FTxs, make possible predictions concerning structure-function relationships among these toxins and the basis of selective toxicity of specific RFS venom 3FTxs. Rear-fanged snake venoms are therefore of considerable research interest due to the evolutionary novelties they contain, providing insights into the evolution of snake venom proteins and potential predator-prey coevolution in a broader phylogenetic context. Because of the limited complexity of these venoms, they represent a more tractable source to inform about the biological roles of specific venom proteins that are found in the venoms of this rich diversity of snakes.


-------------------------------------------


Evolutionary history of burrowing asps (Lamprophiidae: Atractaspidinae) with emphasis on fang evolution and prey selection

April 17, 2019

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214889


-------------------------------------------


Evolution of tiger snake skulls in response to prey type and size between island and mainland populations

Jan 1 2019

https://sciences.adelaide.edu.au/study/honours/honours-projects/evolution-of-tiger-snake-skulls


-------------------------------------------


New fossils shed light on how snakes got their bite and lost their legs

November 20, 2019

https://phys.org/news/2019-11-fossils-snakes-lost-legs.html


--------------------------------------------


Has snake fang evolution lost its bite? New insights from a structural mechanics viewpoint

2017

https://royalsocietypublishing.org/doi/10.1098/rsbl.2017.0293


--------------------------------------------



Remarkable Fossils Push Back Snake Origins by 65 Million Years

January 27, 2015


https://www.scientificamerican.com/article/remarkable-fossils-push-back-snake-origins-by-65-million-years/


--------------------------------------------



An ancient snake’s cheekbone sheds light on evolution of modern snake skulls

Nov 20, 2019

https://www.youtube.com/watch?v=je5Im8Getic


--------------------------------------------



How a Fossilized Snake With Legs Fits Into the Lineage of Lizards

December 6, 2019


“Snakes are just fancy lizards,” says one evolutionary biologist.

https://www.atlasobscura.com/articles/difference-between-legless-lizard-snake



--------------------------------------------



Could Poison Frogs Crush Addiction?

Frog evolution could one day help block nicotine and other substances

https://www.sierraclub.org/sierra/how-poison-frogs-could-crush-addiction



---------------------------------------------



Venoms in medicine

https://en.wikipedia.org/wiki/Venoms_in_medicine


----------------------------------------------



The bite that cures: how we’re turning venom into medicine

July, 2019

https://www.sciencefocus.com/nature/the-bite-that-cures-how-were-turning-venom-into-medicine/


----------------------------------------------



How Animal Venoms Are Helping to Treat a Wide Range of Medical Conditions

2018

https://www.livescience.com/63477-animal-venom-drug-discovery.html


----------------------------------------------



Snake venom components in medicine: From the symbolic rod of Asclepius to tangible medical research and application.

2018

https://www.ncbi.nlm.nih.gov/pubmed/30261311



----------------------------------------------



Venoms That Save Lives

April 4, 2018

https://splice-bio.com/venoms-that-save-lives/

It is common knowledge that the venom from a snake or scorpion can be dangerous. Less known is the fact that several drugs are derived from the toxins of venomous animals. Throughout history, humans have used toxins for medical purposes. Today, modern medicine uses the vast amount of toxins as inspiration for developing novel drugs. Despite the potential of venom-derived drugs, only seven have been approved so far.

Venomous animals have existed for millions of years and are found in ecosystems around the world. There is a distinction between poisonous and venomous animals, due to the difference in how the toxins are delivered. Venomous animals inject their venom into other organisms using a specialized apparatus, such as fangs or a stinger. The venom is produced in a gland attached to this apparatus. In poisonous animals, the entire body, or parts of it, contain the poisonous substance. Poisonous animals are thus harmful when the animal is touched or eaten.



----------------------------------------------


 Scorpions adapt their stinging, stingers and sting contents to minimize costs of venom use

June 10, 2019

https://phys.org/news/2019-06-scorpions-stingers-contents-minimize-venom.html


---------------------------------------------



How venoms are shaping medical advances

https://www.bbcearth.com/blog/?article=how-venoms-are-shaping-medical-advances


----------------------------------------------



Evolutionary Ecology of Fish Venom: Adaptations and Consequences of Evolving a Venom System

December 2018

https://www.mdpi.com/2072-6651/11/2/60/htm



--------------------------------------------



Evolutionary Context of Venom in Animals

28 March 2017


https://link.springer.com/referenceworkentry/10.1007%2F978-94-007-6458-3_16



---------------------------------------------
 

Five unusual toxic animals and their chemical weapons


https://www.medicalnewstoday.com/articles/308864


---------------------------------------------


Platypus Venom: a Review

2007

https://www.researchgate.net/publication/228347583_Platypus_Venom_a_Review


--------------------------------------------


Why Hasn’t Evolution Made Another Platypus?

September 14, 2017

http://nautil.us/issue/52/the-hive/why-hasnt-evolution-made-another-platypus


--------------------------------------------



Out of the Mouths of Snakes

DNA analysis and 3D imaging have revealed how snakes evolved their huge gape independently across different lineages.

http://www.australasianscience.com.au/article/issue-november-2016/out-mouths-snakes.html


----------------------------------------------


The ecological origins of snakes as revealed by skull evolution

2018

https://www.nature.com/articles/s41467-017-02788-3

Abstract

The ecological origin of snakes remains amongst the most controversial topics in evolution, with three competing hypotheses: fossorial; marine; or terrestrial. Here we use a geometric morphometric approach integrating ecological, phylogenetic, paleontological, and developmental data for building models of skull shape and size evolution and developmental rate changes in squamates. Our large-scale data reveal that whereas the most recent common ancestor of crown snakes had a small skull with a shape undeniably adapted for fossoriality, all snakes plus their sister group derive from a surface-terrestrial form with non-fossorial behavior, thus redirecting the debate toward an underexplored evolutionary scenario. Our comprehensive heterochrony analyses further indicate that snakes later evolved novel craniofacial specializations through global acceleration of skull development. These results highlight the importance of the interplay between natural selection and developmental processes in snake origin and diversification, leading first to invasion of a new habitat and then to subsequent ecological radiations.


----------------------------------------------


Activity of Head Muscles During Feeding by Snakes: A Comparative Study

1983

https://academic.oup.com/icb/article/23/2/383/302313


----------------------------------------------



Morphology of the lower jaw and suspensorium in the Texas blindsnake, Leptotyphlops dulcis (Scolecophidia: Leptotyphlopidae).

2006

https://www.ncbi.nlm.nih.gov/pubmed/16429440


----------------------------------------------



Patterns of postnatal ontogeny of the skull and lower jaw of snakes as revealed by micro‐CT scan data and three‐dimensional geometric morphometrics

2016

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108151/


----------------------------------------------


Feeding in Snakes: Form, Function, and Evolution of the Feeding System

http://www.anthonyherrel.fr/publications/Moon%20et%20al%202019%20Feeding%20In%20Vertebrates.pdf


----------------------------------------------



Prey Transport Mechanisms in Blindsnakes and the Evolution of Unilateral Feeding Systems in Snakes

2001

https://www.brown.edu/Departments/EEB/brainerd_lab/pdf/Kley-2001-AmZool.pdf


----------------------------------------------



'Protovipers' and the Evolution of Snake Fangs

1979

https://www.jstor.org/stable/2407632?seq=1


----------------------------------------------


Homology of the Jaw Muscles in Lizards and Snakes—A Solution from a Comparative Gnathostome Approach

31 January 2014

https://anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/ar.22857


---------------------------------------------


Quadrate bone

https://en.wikipedia.org/wiki/Quadrate_bone

The quadrate bone is part of a skull in most tetrapods, including amphibians, sauropsids (reptiles, birds), and early synapsids. In these animals it connects to the quadratojugal and squamosal in the skull, and forms part of the jaw joint (the other part is the articular bone at the rear end of the lower jaw).

It is formed by endochondral ossification and is formed from the hindmost part of the primitive cartilaginous upper jaw.





(Anapsid skull, Quadrate bone marked q)



-----------------------------------------------------------------------




Biomechanical assessment of evolutionary changes in the lepidosaurian skull

May 19, 2009

https://www.pnas.org/content/106/20/8273



-----------------------------------------------


Evolution of postcranial skeleton in worm lizards inferred from its status in the Cretaceous stem-amphisbaenian Slavoia darevskii

https://www.app.pan.pl/archive/published/app62/app002942016.pdf


-----------------------------------------------


A Fossil Snake With Four Legs


https://www.nationalgeographic.com/science/phenomena/2015/07/23/a-fossil-snake-with-four-legs/


-----------------------------------------------


New skulls and skeletons of the Cretaceous legged snake Najash, and the evolution of the modern snake body plan

Nov 2019

https://advances.sciencemag.org/content/5/11/eaax5833

Abstract

Snakes represent one of the most dramatic examples of the evolutionary versatility of the vertebrate body plan, including body elongation, limb loss, and skull kinesis. However, understanding the earliest steps toward the acquisition of these remarkable adaptations is hampered by the very limited fossil record of early snakes. Here, we shed light on the acquisition of the snake body plan using micro–computed tomography scans of the first three-dimensionally preserved skulls of the legged snake Najash and a new phylogenetic hypothesis. These findings elucidate the initial sequence of bone loss that gave origin to the modern snake skull. Morphological and molecular analyses including the new cranial data provide robust support for an extensive basal radiation of early snakes with hindlimbs and pelves, demonstrating that this intermediate morphology was not merely a transient phase between limbed and limbless body plans.


------------------------------------------------


The Origin Of Vertebrates And The Rise Of Fishes

https://www2.gwu.edu/~darwin/BiSc151/Fishes/Fish.html


----------------------------------------------


Moray Eels Are Uniquely Equipped to Pack Big Prey Into Their Narrow Bodies

2007

https://www.nsf.gov/news/news_summ.jsp?cntn_id=109985



----------------------------------------------


The Mystery of the Toothy Eels

https://research.pbsci.ucsc.edu/eeb/mehta/TheMysteryoftheToothyEels.htm


----------------------------------------------


Biting disrupts integration to spur skull evolution in eels

https://www.nature.com/articles/ncomms6505


----------------------------------------------


'Alien' Jaws Help Moray Eels Feed

September 6, 2007

https://www.sciencedaily.com/releases/2007/09/070905134523.htm


----------------------------------------------


Absurd Creature of the Week: This Eel Fires Extra Alien Jaws Out of Its Throat

2014

https://www.wired.com/2014/04/absurd-creature-of-the-week-this-eel-fires-extra-alien-jaws-out-of-its-throat/



----------------------------------------------

 

Sheepshead Fish: Facts About The Fish With Human Teeth

12 Nov 2021

https://www.scienceabc.com/nature/animals/sheepshead-fish-facts-fish-human-teeth.html

 

----------------------------------------------



Evolutionary constraints revealed in diversity of fish skulls

November 17, 2014

Evolution of biting in eels allowed remarkable diversification of skull shapes, whereas suction feeding constrains skull shapes of most fish

https://news.ucsc.edu/2014/11/fish-skulls.html



----------------------------------------------



Thyroid hormone modulation during zebrafish development recapitulates evolved diversity in danionin jaw protrusion mechanics

August 2019


https://onlinelibrary.wiley.com/doi/full/10.1111/ede.12299



----------------------------------------------



Evolution of Levers and Linkages in the Feeding Mechanisms of Fishes

2004

https://www.jstor.org/stable/3884601?seq=1



---------------------------------------------



The Jaw Adductor Muscle Complex in Teleostean Fishes: Evolution, Homologies and Revised Nomenclature (Osteichthyes: Actinopterygii)

April 2, 2013

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060846



---------------------------------------------



Convergent Evolution of Jaws between Spinosaurid Dinosaurs and Pike Conger Eels

2 September 2016

https://bioone.org/journals/acta-palaeontologica-polonica/volume-61/issue-4/app.00284.2016/Convergent-Evolution-of-Jaws-between-Spinosaurid-Dinosaurs-and-Pike-Conger/10.4202/app.00284.2016.full



--------------------------------------------



Did Eels Evolve Better By Biting?

2014

https://answersingenesis.org/aquatic-animals/did-eels-evolve-better-by-biting/



---------------------------------------------



Biting releases constraints on moray eel feeding kinematics

2007

https://jeb.biologists.org/content/210/3/495



---------------------------------------------



Concealed Weapon: Eels' Second Set of Teeth

September 6, 2007

https://www.npr.org/transcripts/14194579



---------------------------------------------



Moray Eel Evolution Baffles Scientists; 'Species Don’t Do That'

https://www.underwatertimes.com/news.php?article_id=90271085346



---------------------------------------------



How the European eel (Anguilla anguilla) loses its skeletal framework across lifetime

https://royalsocietypublishing.org/doi/full/10.1098/rspb.2016.1550

Abstract

European eels (Anguilla anguilla) undertake an impressive 5 000 km long migration from European fresh waters through the North Atlantic Ocean to the Sargasso Sea. Along with sexual maturation, the eel skeleton undergoes a remarkable morphological transformation during migration, where a hitherto completely obscure bone loss phenomenon occurs. To unravel mechanisms of the maturation-related decay of the skeleton, we performed a multiscale assessment of eels' bones at different life-cycle stages. Accordingly, the skeleton reflects extensive bone loss that is mediated via multinucleated bone-resorbing osteoclasts, while other resorption mechanisms such as osteocytic osteolysis or matrix demineralization were not observed. Preserving mechanical stability and releasing minerals for energy metabolism are two mutually exclusive functions of the skeleton that are orchestrated in eels through the presence of two spatially segregated hard tissues: cellular bone and acellular notochord. The cellular bone serves as a source of mineral release following osteoclastic resorption, whereas the mineralized notochord sheath, which is inaccessible for resorption processes due to an unmineralized cover layer, ensures sufficient mechanical stability as a part of the notochord sheath. Clearly, an eel's skeleton is structurally optimized to meet the metabolic challenge of fasting and simultaneous sexual development during an exhausting journey to spawning areas, while the function of the vertebral column is maintained to achieve this goal.



--------------------------------------------



Elongation of the Body in Eels

December 2010

https://academic.oup.com/icb/article/50/6/1091/633110




---------------------------------------------



Meet a lamprey. Your ancestors looked just like it

2015


http://www.bbc.com/earth/story/20151102-meet-a-lamprey-your-ancestors-looked-just-like-it




---------------------------------------------




14 Fun Facts About Hagfish

2012

These frightening creatures defend themselves with slime and chow down on animal carcasses

https://www.smithsonianmag.com/science-nature/14-fun-facts-about-hagfish-77165589/



---------------------------------------------

 

Evolution and genomic organization of muscle microRNAs in fish genomes

2014

https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-014-0196-x

Background

MicroRNAs (miRNAs) are small non-coding RNA molecules with an important role upon post-transcriptional regulation. These molecules have been shown essential for several cellular processes in vertebrates, including muscle biology. Many miRNAs were described as exclusively or highly expressed in skeletal and/or cardiac muscle. However, knowledge on the genomic organization and evolution of muscle miRNAs has been unveiled in a reduced number of vertebrates and mostly only reflects their organization in mammals, whereas fish genomes remain largely uncharted. The main goal of this study was to elucidate particular features in the genomic organization and the putative evolutionary history of muscle miRNAs through a genome-wide comparative analysis of cartilaginous and bony fish genomes.



---------------------------------------------




‘Humans are just modified fish’

MONASH UNIVERSITY    6 OCT 2011

 https://www.sciencealert.com/were-all-just-modified-fish

Three Australian fish – including the iconic lungfish – have provided an insight into the evolution of human beings.

A team of scientists led by Professor Peter Currie, Australian Regenerative Medicine Institute at Monash University and Dr Nicholas Cole, University of Sydney, have discovered how the muscles controlling the pelvic fins of some fish have cleared the way for the evolution of back legs in higher animals.

This innovation gave rise to the tetrapods, or four-legged creatures, along with our distant ancestors who made the first steps onto land some 400 million years ago.

Professor Currie said the genetics of a fish are not vastly different to our own.

“We have shown that the mechanism of pelvic muscle formation in bony fish is transitional between that in sharks and in our tetrapod ancestors.

“By examining the way the different fish species generated the muscles of their pelvic fins we were able to uncover the evolutionary forerunners of the hind limbs. Humans are just modified fish,” said Professor Currie.

Scientists have long known that the ancient lungfish species are the ancestors of the tetrapods. These fish could survive on land, breathing air and using their pelvic fins to propel themselves.

Australia is home to three species of the few remaining lungfish – two marine species and one inhabiting Queensland’s Mary River basin.

There have been big gaps in the knowledge of these fish until now. Most of the conclusions have been drawn from fossil skeletons, but the muscles critical to locomotion cannot be preserved in the fossil record.

The scientists used fish living today to trace the evolution of pelvic fin muscles to find out how the load bearing hind limbs of the tetrapods evolved.

To find differences in pelvic fin muscle formation, the researchers compared embryos of the descendants of species representing key turning points in vertebrate evolution.

They studied primitive cartilaginous fish: Australia’s bamboo shark and its cousin, the elephant shark; and three bony fish: the Australian lungfish, the zebrafish and the American paddlefish.

The scientists genetically engineered fish to trace the migration of precursor muscle cells in early developmental stages as the animal’s body took shape. These cells in the engineered fish emitted red or green light.

The team found that the bony fish had a different mechanism of pelvic fin muscle formation from that of the cartilaginous fish, a mechanism that was a stepping stone to the evolution of tetrapod physiology.

The full research article, Development and Evolution of the Muscles of the Pelvic Fin can be viewed at PLoS Biology.




---------------------------------------------


Lungfish provides insight to life on land: 'Humans are just modified fish'

2011

 https://www.sciencedaily.com/releases/2011/10/111004180106.htm


---------------------------------------------


Lungfish: This fish can stay alive inside the ground for 4 years!

2017

A fish that can breathe oxygen directly from the air? Yes, this ancient species of fish still exists! Know more about them here.

https://www.indiatoday.in/education-today/gk-current-affairs/story/lungfish-961065-2017-02-17


---------------------------------------------


Transition in organ function during the evolution of air-breathing; insights from Arapaima gigas, an obligate air-breathing teleost from the Amazon

2004

 http://jeb.biologists.org/content/207/9/1433



---------------------------------------------



Molecular cloning and characterization of pirarucu (Arapaima gigas) follicle-stimulating hormone and luteinizing hormone ÎČ-subunit cDNAs

 2017

 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183545



---------------------------------------------



Whole Genome Sequencing of the Pirarucu (Arapaima gigas) Supports Independent Emergence of Major Teleost Clades

2018

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143160/

Arapaima gigas belongs to the superorder Osteoglossomorpha of bony-tongued fishes whose tongue contains sharp bony teeth for disabling and shredding preys (Sanford and Lauder 1990; Burnie and Wilson 2001). Together with Elopomorpha (eels and tarpons) and Clupeocephala (most of extant fish species), the Osteoglossomorpha comprises one of the three main teleosts groups whose phylogenetic position has been controversial (Le et al. 1993; Inoue et al. 2003; Near et al. 2012; Betancur-R 2013; Faircloth et al. 2013; Chen et al. 2015; Hughes et al. 2018). Fossil records and some early molecular studies, including a recent comprehensive analysis of >300 Actinopterygii species (Hughes et al. 2018), placed Osteoglossomorpha as the oldest teleost group (Greenwood 1970; Inoue et al. 2003), while other studies placed Elopomorpha as the most ancestral one (Near et al. 2012; Betancur-R 2013; Faircloth et al. 2013). Recently, a phylogenetic study based on whole genome sequencing of the bony-tongued Asian arowana (Scleropages formosus) suggested that the branching of Elopomorpha and Osteoglossomorpha occurred almost simultaneously, placing them as sister lineages of Clupeocephala (Bian 2016). Within this context, the genome of the Pirarucu provides new insights to study the evolutionary history of teleosts as well as providing useful information for sustainable exploration of this giant Amazon fish. Here, we present the first whole genome assembly, gene annotation, and phylogenomic inference of the Pirarucu which should facilitate the molecular characterization and conservation of this economically important fish species.


---------------------------------------------

 

Evolution of the vertebrate jaw: homology and developmental constraints

2003

https://bioone.org/journals/paleontological-research/volume-7/issue-1/prpsj.7.89/Evolution-of-the-vertebrate-jaw-homology-and-developmental-constraints/10.2517/prpsj.7.89.full



----------------------------------------------



Ecomorphological diversification in squamates from conserved pattern of cranial integration

2018

https://www.pnas.org/content/116/29/14688



-----------------------------------------------



Cranial ontogeny of Thamnophis radix (Serpentes: Colubroidea) with a re-evaluation of current paradigms of snake skull evolution

07 August 2019

https://royalsocietypublishing.org/doi/10.1098/rsos.182228



-----------------------------------------------



A Snake Version of Lucy

 August 4, 2012

https://answersingenesis.org/reptiles/snake-version-lucy/



-----------------------------------------------



Yale researchers identify ‘missing-link snake’

2012

https://news.yale.edu/2012/07/25/few-bones-most-primitive-snake-emerges



-----------------------------------------------



 10 Foot Sea Snake with Weird Hole in Its Skull Found to Breath Through the Top of Its Head

 9/4/19

https://www.newsweek.com/sea-snake-breaths-through-hole-top-head-1457563



-----------------------------------------------



Before Agriculture, Human Jaws Were a Perfect Fit for Human Teeth

2015

The emergence of agricultural practices initiated major changes to the jaw structure of ancient humans, leading to dental problems we still experience

https://www.smithsonianmag.com/smart-news/how-dawn-farming-changed-our-mouths-worst-180954167/



-----------------------------------------------



Birth of farming caused jaw-dropping changes to the human skull, scientists find

25 August 2017

https://www.telegraph.co.uk/science/2017/08/25/birth-farming-caused-jaw-dropping-changes-human-skull-scientists/



-----------------------------------------------



Do Muscles Constrain Skull Shape Evolution in Strepsirrhines?

2018

https://www.ncbi.nlm.nih.gov/pubmed/29330958



-----------------------------------------------



 Functional relationships in the jaw apparatus of the chameleons and the evolution of adaptive complexes

29 March 2017

https://link.springer.com/article/10.1134/S1062359016110066




-----------------------------------------------------------




Does diet drive the evolution of head shape and bite force in chameleons of the genus Bradypodion? 


21 September 2016

https://besjournals.onlinelibrary.wiley.com/doi/full/10.1111/1365-2435.12750



------------------------------------------------------------



The evolution of cranial design and performance in squamates: Consequences of skull-bone reduction on feeding behavior


 02 May 2007

https://academic.oup.com/icb/article/47/1/107/633197


------------------------------------------------------------


The only complete articulated early Miocene chameleon skull (Rusinga Island, Kenya) suggests an African origin for Madagascar’s endemic chameleons


10 January 2020

https://www.nature.com/articles/s41598-019-57014-5


------------------------------------------------------------



Kenyan fossil reveals chameleons may have 'rafted' from Africa to Madagascar


February 10, 2020

https://phys.org/news/2020-02-kenyan-fossil-reveals-chameleons-rafted.html



------------------------------------------------------------



'Cryptic intermediates' and the evolution of chameleons


2008

https://scienceblogs.com/tetrapodzoology/2008/06/07/agamids-and-chameleons





----------------------------------------------




Chameleons do more than change color – their bones glow in the dark



 



https://massivesci.com/articles/chameleons-glow-dark-skeletons-animals/



------------------------------------------------------------



Widespread bone-based fluorescence in chameleons

2017

https://research.vu.nl/ws/portalfiles/portal/44414519/Pr_tzel_et_al_2018_Scientific_Reports.pdf



------------------------------------------------------------



Hand/foot splitting and the ‘re-evolution’ of mesopodial skeletal elements during the evolution and radiation of chameleons


18 September 2015


https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-015-0464-4



------------------------------------------------------------



Chameleon radiation byoceanic dispersal


http://biology.kenyon.edu/courses/biol241/raxworthy%20chameleon%20radiation.pdf



----------------------------------------------





 So, Amphibians Glow. Humans Just Couldn't See It—Until Now

02.27.2020












Bathe an amphibian in blue light and it glows a brilliant green. But what does this all mean?

https://www.wired.com/story/amphibians-glow/



--------------------------------------




 Scientists Have Discovered These Toxic Frogs Have Bones Glowing Through Their Skin

25 APRIL 2019

Deep in the Brazilian Atlantic Forest live tiny frogs that are bright orange, toxic, and glow ultraviolet, thanks to revelations from new research.

It's the first known case of an amphibian showing "exceptional" fluorescence right through their skin.

https://www.sciencealert.com/these-cute-little-orange-frogs-have-a-florescent-secret-under-their-skin



------------------------------------



Intense bone fluorescence reveals hidden patterns in pumpkin toadlets

(2019)


https://www.nature.com/articles/s41598-019-41959-8

















(Fluorescence in pumpkin toadlets. Ethanol-preserved specimens of Brachycephalus pitanga (ac), B. ephippium (eg) and Ischnocnema parva (k), and live Ischnocnema parva (i,j) photographed in natural light (a,e,i) and showing fluorescence under UV illumination using two Fluotest Forte UV (λexcitation centred around 365 nm; b,f,j) and a laboratory UV light source (λexcitation = 365 nm) and an emission filter centred around 472 nm and 30 nm wide, thereby eliminating reflectance of all visible light (c,g,k). Note that the absence of fluorescence in I. parva results in a completely dark image (k). Computerized micro-tomography (”CT) reconstructions (c,h,l) show the correspondence between fluorescent patterns and bone structure in B. pitanga (d), B. ephippium (h) and I. parva (l). Photographs taken by L.C. and S.G. (a,b,e,f,i,j) and P.G., M.T. and S.G. (c,g,k).













(Fluorescence distribution within the bone in Brachycephalus ephippium. Photomicrograph of a transverse, non-decalcified section of the dorsal bony plates at 10x (a) and an enlargement of the boxed area at 40x magnification (b). The section is illuminated with UV-A light (λexcitation = 365 nm) and no emission filter was used).



------------------------------------



Did dinosaurs glow in the dark? Scientists suggest photoluminescent skin

3 Mar 2020

https://metro.co.uk/2020/03/03/dinosaurs-glow-dark-12339023/














(Many deep sea creatures release UV light as visible light is so low)


















(There are more than 180 species that are known to glow in the dark)




------------------------------------





Did Dinosaurs and Pterosaurs 'Glow'? Extinct Archosaurs and the Capacity for Photoluminescent Visual Displays

2020

http://tetzoo.com/blog/2020/3/2/dinosaurs-pterosaurs-uv-sensitive-visual-displays









(In 2018, Jamie Dunning and colleagues reported the discovery of photoluminescence in puffins).




------------------------------------




Bioluminescence

https://en.wikipedia.org/wiki/Bioluminescence








(Flashing of photophores of black dragonfish, Malacosteus niger, showing red fluorescence)



-----------------------------------------------------------




 Cranwell's frog looks otherworldly when exposed to blue light and imaged with a special filter. Now, scientists have to figure out why.



https://www.wired.com/story/amphibians-glow/



--------------------------------------------------------




Glowing Amphibians Extremely Common

Feb 28, 2020



 https://www.the-scientist.com/news-opinion/glowing-amphibians-extremely-common-67204


A study of the animals using blue light reveals what humans are not able to see with the naked eye.


Dozens of salamanders and other amphibians are biofluorescent under blue light, according to a study published Thursday (February 27) in Scientific Reports. On land, blue light is common after the sun has set, which may explain why amphibians, particularly nocturnal ones, react to it.

Many land animals, such as penguins, some rodents, and some amphibians, are known to fluoresce under ultraviolet light (360–380 nm), but most species known to fluoresce under blue light (440–460 nm) are strictly aquatic animals such as fish and turtles, as that is the wavelength of light that cuts through water the most.

Two biologists from St. Cloud State University, Jennifer Lamb and Matthew Davis, had decided to expose salamanders they were studying to blue light and found that they lit up. To understand how widespread the trait may be, the team was granted access to the Shedd Aquarium in Chicago. Using a flashlight that shone blue light, they analyzed eight salamander families, five frog families, and one family of caecilians, which are limbless amphibians. They found that across the board, all of the animals glowed.



 


A. opacum (left) fluoresces from its bones, especially in the digits and cloacal area, while A. tigrinum (right) glows brightly from the same places on its skin that are brightly-colored in the visible spectrum of light.






------------------------------------



Why Bioluminescence Evolved to Be Red Light, and Blue

The laws of nature constrict living light to a few hues, which also happen to be quite patriotic

https://www.smithsonianmag.com/science-nature/why-bioluminescence-evolved-be-red-light-and-blue-180969435/


------------------------------------------


{The cannabis plant thrives in the Red light spectrum and the Blue light spectrums}.


-------------------------------------------


What is the Best LED Spectrum for Indoor Growing?

April 15, 2019

https://news.californialightworks.com/what-is-the-best-led-spectrum-for-growing/


How the Light Spectrum Affects Plants

When we talk about the light spectrum, we’re speaking specifically about the distribution of red, blue, and UVB light. So the first thing to understand is how each color influences your plants. In the most basic terms:

Red light promotes flowering. However, it also encourages vertical plant growth. Too much red at the wrong time will cause your plants to stretch, which results in lower yields and lanky, unstable plants.

Blue light is your secret weapon for amping up the concentration of oils and resin.

UVB light puts your plants on the defensive . . . in a good way. Just as we humans do, plants actively protect themselves from the sun’s UVB rays. But instead of sunblock, they produce more trichomes, ultimately increasing potency, flavor, and fragrance.

Now, let’s talk about when to use which color spectrum.


Clones

If you’re starting with clones, your first goal is to encourage rooting. This takes some effort on your plants’ part, so keep the light intensity low. If you stick to about 25% red and 45% blue and white, your plants is more likely to focus energy on deepening roots rather than expanding upward.



 -------------------------------------------------------------

--------------------------------------------------------------



{Do animals and humans share the same type of evolution process or do humans evolve differently.
We can see how plants and animals can slowly adapt and evolve to their surroundings as well,
and even viruses can mutate. There is so much confusion to evolution, de-evolution and mutation that it is often difficult for many experts to fully understand how this process works.

We can see how you can breed a white cannabis plant that smell like pine with a purple cannabis plant that smells like a berry and get a half white and half purple cannabis plant. You also get the two smells of both of the white and purple cannabis plant, such as a Pine and Berry smell from the newly evolved plant that is now a new strain of cannabis. You can get good genetics and good evolution of a plant and we see how over time that a species can de-evovle and degenerate to a browned up bunk looking Mexican type schwag weed, this also goes for humans as well. Then if you try to cross good cannabis with cannabis that has degenerated, the offspring of the plant can still be decent but still not as good as the original parent and strain once the weed has been too browned up. This does not go for every strain and there are some good strains with Green and Brown hairs, but most know about the type of brown degenerative ditch weed that I am talking about}.




 -------------------------------------------------------------------------------





 





-----------------------------------------------------------------------------------


 Why are higher plants green? Evolution of the higher plant photosynthetic pigment complement

http://www.esalq.usp.br/lepse/imgs/conteudo_thumb/Why-are-higher-plants-green--Evolution-of-the-higher-plant-photosynthetic-pigment-complement-1.pdf


----------------------------------------


Independent evolution of the prochlorophyte and green plant chlorophyll a/b light-harvesting proteins

1996

https://www.pnas.org/content/93/26/15244


----------------------------------------



The Light Spectrum Matters When Growing Cannabis

https://leafist.com/news/growing/the-light-spectrum-matters-when-growing-cannabis

 


-----------------------------------------



Opinions wanted on green light in flowering room after lights out

Mar 11, 2016

https://www.420magazine.com/community/threads/opinions-wanted-on-green-light-in-flowering-room-after-lights-out.271859/


----------------------------------------


Chromatic adaptation and the evolution of light color sensing in cyanobacteria


https://www.pnas.org/content/107/20/9029


----------------------------------------


All the Colors That Human Vision Neglects

February 7, 2018

To help us survive, our eyes have to make some sacrifices.


https://www.theatlantic.com/science/archive/2018/02/seeing-red/552473/



---------------------------------------


Evolution of human colour vision

https://en.wikipedia.org/wiki/Evolution_of_human_colour_vision



-------------------------------------------------------------------------------------



5 animals and some amazing facts about their eyes

24 July 2017

https://www.feelgoodcontacts.com/blog/5-animals-and-some-amazing-facts-about-their-eyes

 


--------------------------------------------------------------



Nocturnal colour vision – not as rare as we might think

https://jeb.biologists.org/content/209/5/781

 


--------------------------------------------------------------


The Causes and Consequences of Color Vision

02 October 2008

https://evolution-outreach.biomedcentral.com/articles/10.1007/s12052-008-0088-x


--------------------------------------------------------------



Snakes hear by detection of sound-induced skull vibrations

https://www.frontiersin.org/10.3389/conf.fnbeh.2012.27.00110/event_abstract

 


--------------------------------------------------


 Comparative Skull Osteology of Karsenia koreana (Amphibia, Caudata, Plethodontidae)

2010

https://ib.berkeley.edu/labs/wake/364_Buckley et al 2010 osteology skull Karsenia koreana.pdf


---------------------------------------------



A missing link settles debate over the origin of frogs and salamanders


21-May-2008


The description of an ancient amphibian that millions of years ago swam in quiet pools and caught mayflies on the surrounding land in Texas has set to rest one of the greatest current controversies in vertebrate evolution. The discovery was made by a research team led by scientists at the University of Calgary.

The examination and detailed description of the fossil, Gerobatrachus hottoni (meaning Hotton's elder frog), proves the previously disputed fact that some modern amphibians, frogs and salamanders evolved from one ancient amphibian group called temnospondyls.


https://www.eurekalert.org/pub_releases/2008-05/uoc-aml052008.php



--------------------------------------------



Heterochrony and Neotenic Salamanders: Possible Clues for Understanding the Animal Development and Evolution

https://bioone.org/journals/zoological-science/volume-13/issue-6/zsj.13.765/Heterochrony-and-Neotenic-Salamanders--Possible-Clues-for-Understanding-the/10.2108/zsj.13.765.pdf


-------------------------------------------



Quantitative Genetics and Evolution of Head Shape in Plethodon Salamanders

2011

https://www.eeob.iastate.edu/faculty/adams/files/page/files/2011-adams-evolbiol.pdf



---------------------------------------------



Amphibian skull evolution: the developmental and functional context of simplification, bone loss and heterotopy.

 
2014

https://www.semanticscholar.org/paper/Amphibian-skull-evolution%3A-the-developmental-and-of-Schoch/ee78b11418c3197b068f0abb3111089478b84144


---------------------------------------------




Evolution, Ecology, and Behavior Students and Postdocs

https://sib.illinois.edu/eeb/students



---------------------------------------------


Development of the bony skeleton in the Taiwan salamander, Hynobius formosanusMaki, 1922 (Caudata: Hynobiidae): Heterochronies and reductions

https://www.senckenberg.de/wp-content/uploads/2019/08/11_vertebrate_zoology_65-1_vassileva_et_al_117-130.pdf


---------------------------------------------



Cranial biomechanics in basal urodeles: the Siberian salamander (Salamandrella keyserlingii) and its evolutionary and developmental implications


2017

https://www.nature.com/articles/s41598-017-10553-1


---------------------------------------------


Osteological Variation among Extreme Morphological Forms in the Mexican Salamander Genus Chiropterotriton (Amphibia: Plethodontidae): Morphological Evolution And Homoplasy

June 10, 2015


https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127248


---------------------------------------------


Evolution of skull shape in the family Salamandridae (Amphibia: Caudata)

14 December 2017

https://onlinelibrary.wiley.com/doi/full/10.1111/joa.12759


----------------------------------------------


The skull and jaw musculature as guides to the ancestry of salamanders

2008

https://academic.oup.com/zoolinnean/article-abstract/68/1/1/2658646?redirectedFrom=fulltext


----------------------------------------------


Skull Development in Two Plethodontid Salamanders (Genus Desmognathus) with Different Life Histories

https://link.springer.com/chapter/10.1007/978-1-4615-4255-1_12


----------------------------------------------


Skull Growth in Cannibalistic Tiger Salamanders, Ambystoma tigrinum

1993

https://www.jstor.org/stable/3671609?seq=1



----------------------------------------------


Loading mechanics of the femur in tiger salamanders (Ambystoma tigrinum) during terrestrial locomotion

2011

https://jeb.biologists.org/content/214/15/2603


----------------------------------------------



New species of earliest-known salamanders found in China

March 25, 2003

https://www.uchicagomedicine.org/forefront/news/new-species-of-earliest-known-salamanders-found-in-china

 


-----------------------------------------------


How the World's Largest Salamander Feed?

04/2015








https://www.uab.cat/web?cid=1096481466574&pagename=UABDivulga%2FPage%2FTemplatePageDetallArticleInvestigar&param1=1345683918994


----------------------------------------------


The early formation of the skull in extant and Paleozoic amphibians

2002

https://www.cambridge.org/core/journals/paleobiology/article/early-formation-of-the-skull-in-extant-and-paleozoic-amphibians/BB69149CBB05835FB42D9A5AA7DD1005



-----------------------------------------------


Morphological evolution and modularity of the caecilian skull

22 January 2019


https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-018-1342-7


----------------------------------------------------


Glowing Salamanders Shine Light on Evolution

https://newsroom.carleton.ca/story/glowing-salamanders/


-----------------------------------------------------


Extraordinary Salamander Can Grow New Limbs and Has Longest Genome Ever Sequenced

1/25/18

https://www.newsweek.com/axolotls-masters-regeneration-have-insanely-long-genomes-791052


-----------------------------------------------


From Land to Water: the Origin of Whales, Dolphins, and Porpoises

16 April 2009

https://evolution-outreach.biomedcentral.com/articles/10.1007/s12052-009-0135-2


-----------------------------------------------


Learn About Dolphin Evolution

https://dolphin-academy.com/learn/evolution


-----------------------------------------------


 First Fossil Platanistid Dolphin Skull at CMM

http://www.calvertmarinemuseum.com/DocumentCenter/View/702/Volume-21-Number-1-March-2006?bidId=


------------------------------------------------


 From Land to Water: the Origin of Whales, Dolphins, and Porpoises

2009

https://link.springer.com/article/10.1007/s12052-009-0135-2


---------------------------------------------------


THE EVOLUTION OF ARCTIC MARINE MAMMALS

https://esajournals.onlinelibrary.wiley.com/doi/pdf/10.1890/06-0624.1


---------------------------------------------------


Evolution of Marine Mammals: Back to the Sea After 300 Million Years

2007

https://anatomypubs.onlinelibrary.wiley.com/doi/pdf/10.1002/ar.20545


---------------------------------------------------


How did swimming behavior evolve in seals, sea lions and walruses?

May 29, 2016

https://www.burkemuseum.org/news/how-did-swimming-behavior-evolve-seals-sea-lions-and-walruses


---------------------------------------------------


The Origin and Evolutionary Biology of Pinnipeds: Seals, Sea Lions, and Walruses

2018

https://www.annualreviews.org/doi/full/10.1146/annurev-earth-082517-010009


---------------------------------------------------


A new tuskless walrus from the Miocene of Orange County, California, with comments on the diversity and taxonomy of odobenids

2018

https://www.researchgate.net/publication/328251879_A_new_tuskless_walrus_from_the_Miocene_of_Orange_County_California_with_comments_on_the_diversity_and_taxonomy_of_odobenids


---------------------------------------------------


Ancient walrus made do without tusks

2015

https://www.cbsnews.com/news/ancient-walrus-made-do-without-tusks/


---------------------------------------------------


Ancient DNA reveals the chronology of walrus ivory trade from Norse Greenland

2018

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111184/


---------------------------------------------------


Arctic fossil shows how seals evolved

April 2009

https://www.abc.net.au/science/articles/2009/04/23/2550437.htm


---------------------------------------------------


Walking Seal Called Missing Link in Evolution

2009

https://www.livescience.com/7715-walking-seal-called-missing-link-evolution.html


---------------------------------------------------


Graduate student makes major discovery about seal evolution

February 19, 2014

https://phys.org/news/2014-02-student-major-discovery-evolution.html


---------------------------------------------------


Scientists are studying sea lion brains to try to figure out how our own got to be so big

https://qz.com/672594/scientists-are-studying-sea-lion-brains-to-try-to-figure-out-how-our-own-got-to-be-so-big/


---------------------------------------------------


Scientists establish first map of the sea lion brain

Apr. 27, 2016

https://news.vanderbilt.edu/2016/04/27/scientists-establish-first-map-of-the-sea-lion-brain/


---------------------------------------------------


Skull allometry and sexual dimorphism in the ontogeny of the southern elephant seal (Mirounga leonina)


2013

https://www.nrcresearchpress.com/doi/10.1139/cjz-2013-0106#.XoRBtHJOlPY


---------------------------------------------------


Written in Bone: was the fossil Allodesmus a seal or sea lion?


https://experiment.com/projects/written-in-bone-was-the-fossil-allodesmus-a-seal-or-sea-lion


---------------------------------------------------


Fossil Focus: Seals, sea lions and walruses

https://www.palaeontologyonline.com/articles/2015/fossil-focus-seals-sea-lions-walruses/?doing_wp_cron=1585725777.9788990020751953125000


----------------------------------------------------


Tracing early stages of species differentiation: Ecological, morphological and genetic divergence of GalĂĄpagos sea lion populations

2008

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408593/


--------------------------------------------------


Flippers or Feet? An Extinct Mammal May Have Been Replaced By Today's Sea Cows

https://ocean.si.edu/ocean-life/marine-mammals/flippers-or-feet-extinct-mammal-may-have-been-replaced-todays-sea-cows


----------------------------------------------



 How Does a Fish Get Its Shape? Students Explore Smithsonian National Fish Collection to Find Answers

February 04, 2019

https://biology.ucdavis.edu/news/how-does-fish-get-its-shape-students-explore-smithsonian-national-fish-collection-find-answers



-----------------------------------


World’s oldest fish shows how ancient skull evolved

April 18, 2019

https://knowridge.com/2019/04/worlds-oldest-fish-shows-how-ancient-skull-evolved/


-----------------------------------


Neurocranial anatomy of an enigmatic Early Devonian fish sheds light on early osteichthyan evolution

May 29, 2018

https://elifesciences.org/articles/34349


-----------------------------------



 This tiny fish could be your ancestor, say scientists

January 13, 2015

A 415-million-year-old tiny fish skull unearthed in Siberia could revise our understanding of the origins of all jawed vertebrates.

https://www.csmonitor.com/Science/2015/0113/This-tiny-fish-could-be-your-ancestor-say-scientists



-----------------------------------




 Jawless fish brains more similar to ours than previously thought

February 16, 2016

http://www.geologypage.com/2016/02/jawless-fish-brains-more-similar-to-ours-than-previously-thought.html



--------------------------------------------------------




Ancient fish fossil discovered in Canada is a 'missing link' in evolution of hand bones

18 March 2020









https://www.abc.net.au/news/science/2020-03-19/ancient-fish-had-finger-bones-like-a-human/12063308


---------------------------------------------------




Ancient 4-limbed fish reveals origin of human hand

March 27, 2020

https://earthsky.org/earth/elpistostege-ancient-4limbed-fish-fin-origin-human-hand



---------------------------------------------------



 Tiktaalik fossils reveal how fish evolved into four-legged land animals

Jan 2014

A fish called Tiktaalik that lived 375m years ago already had strong hind limbs – even though it still lived in water

https://www.theguardian.com/science/2014/jan/13/tiktaalik-fossil-fish-four-legged-land-animal



----------------------------------------------------



Antarctic fish skull structure reveals patterns of evolution in an extreme environment

 January 24, 2017

https://cos.northeastern.edu/news/antarctic-fish-skull-structure-reveals-patterns-evolution-extreme-environment/

 


---------------------------------------------------



Fish to Amphibian Transition

Copyright 1997 G.R.Morton. This may be freely distributed as long as no change is made to the text and no charge is made.

https://chem.tufts.edu/science/evolution/fish-amphibian-transition.htm


---------------------------------------------------



The evolution of cranial design, diet, and feeding mechanisms in batoid fishes

July 2007

https://academic.oup.com/icb/article/47/1/70/635524




--------------------------------------------------------



Where we split from sharks: common ancestor comes into focus

June 12, 2012

https://www.uchicagomedicine.org/forefront/news/where-we-split-from-sharks-common-ancestor-comes-into-focus


--------------------------------------------------------



Body plan convergence in the evolution of skates and rays (Chondrichthyes: Batoidea)

April 2012

https://www.researchgate.net/publication/51973194_Body_plan_convergence_in_the_evolution_of_skates_and_rays_Chondrichthyes_Batoidea



--------------------------------------------------------

How the Devil Ray Got Its Horns: The Evolution and Development of Cephalic Lobes in Myliobatid Stingrays (Batoidea: Myliobatidae)

13 November 2018

https://www.frontiersin.org/articles/10.3389/fevo.2018.00181/full

--------------------------------------------------------


Catfish use complex coordination to catch prey

April 16, 2019

Using a powerful X-ray imaging system, Brown University scientists found that catfish move joints throughout their head in a concerted manner to suck in their prey.

https://www.brown.edu/news/2019-04-16/catfish


---------------------------------------------------


Researchers solve mystery of deep-sea fish with tubular eyes and transparent head

February 23, 2009


https://www.mbari.org/barreleye-fish-with-tubular-eyes-and-transparent-head/


--------------------------------------------------


Thyroid hormone & fish jaw protrusion

https://www.biorxiv.org/content/10.1101/418483v1.full.pdf


---------------------------------------------------



Birth of Jaws: Tiny Fish May Be Ancient Ancestor

January 12, 2015

https://www.livescience.com/49417-jawed-vertebrates-common-ancestor.html


--------------------------------------------------


The Improbable—but True—Evolutionary Tale of Flatfishes

May 7, 2014

For Charles Darwin, flatfish like flounder were a vexing puzzle—how did they evolve into such asymmetrical freaks? But recently, scientists using clever experiments and advanced imaging have shown just how their curious anatomies came about.

https://www.pbs.org/wgbh/nova/article/flatfish-evolution/


--------------------------------------------------



Blind fish find food thanks to their twisted heads

May 25, 2017

https://newatlas.com/blind-mexican-cavefish-asymmetrical-head/49695/


--------------------------------------------------


Flinders Uni study sheds light on why ancient coelacanth fish’s skull is 100 times bigger than its brain

April 18, 2019

There’s not much going on between the gills of this fish that’s outlived the dinosaurs — its brain cavity is 100 times bigger than the brain itself. Now a Flinders University study has found out why.

https://www.news.com.au/national/south-australia/flinders-uni-study-sheds-light-on-why-ancient-coelacanth-fishs-skull-is-100-times-bigger-than-its-brain/news-story/3975b685b032a9e1434e8155056195f3


--------------------------------------------------


It’s less than 2cm long, but this 400 million year old fossil fish changes our view of vertebrate evolution

May 29, 2018

https://theconversation.com/its-less-than-2cm-long-but-this-400-million-year-old-fossil-fish-changes-our-view-of-vertebrate-evolution-96419

Published today, our new paper describes a spectacular 400 million-year-old 3D-preserved fossil fish, Ligulalepis.

The 3D anatomy of the fossilised Ligulalepis skull reveals previously unknown details of the pattern of dermal skull bones, the shape of the brain cavity, and other soft tissue features (such as nerves and blood vessels) in this species.

Why are we so excited about discovering the structure of an ancient fish skull? Because Ligulalepis sits in a very important position in the vertebrate evolutionary tree.



-----------------------------------------------------------------



Evolution of Levers and Linkages in the Feeding Mechanisms of Fishes


November 2004


https://academic.oup.com/icb/article/44/5/378/799576



-----------------------------------------------------------------



Neurocranium shape variation of piranhas and pacus (Characiformes: Serrasalmidae) in association with ecology and phylogeny

2018

http://www.anthonyherrel.fr/publications/Boyle%20&%20Herrel%202018%20Biol%20J%20Linn%20Soc.pdf


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Piranhas and plant-eating kin replace half their teeth at once

December 4, 2019

This tooth-swapping strategy probably helps keep the fishes’ chompers sharp

https://www.sciencenewsforstudents.org/article/piranhas-and-plant-eating-kin-replace-half-their-teeth-once


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Piranhas and their plant-eating relatives, pacus, replace rows of teeth all at once

October 24, 2019

Not losing teeth individually might help distribute wear and tear from the fishes’ diets more evenly

https://www.sciencenews.org/article/piranhas-plant-eating-relatives-pacus-replace-rows-teeth-all-at-once


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A Piranha-like Pycnodontiform Fish from the Late Jurassic

2018

https://www.cell.com/current-biology/pdfExtended/S0960-9822(18)31208-9


---------------------------------------------------------------


A unique Cretaceous–Paleogene lineage of piranha-jawed pycnodont fishes

(2017)

https://www.nature.com/articles/s41598-017-06792-x


---------------------------------------------------------------



Mega-Bites: Extreme jaw forces of living and extinct piranhas (Serrasalmidae)

2012


https://www.nature.com/articles/srep01009



-----------------------------------------------------------------




Evolution and development of the fish jaw skeleton.

2019

https://www.ncbi.nlm.nih.gov/pubmed/30378758



--------------------------------------------------



Ancient Shark Fossil Provides Insight into Jaw Evolution in Vertebrates

https://blog.everythingdinosaur.co.uk/blog/_archives/2014/04/20/ancient-shark-fossil-provides-insight-into-jaw-evolution-in-vertebrates.html



-----------------------------------------------



Evolution of fish

https://en.wikipedia.org/wiki/Evolution_of_fish



-----------------------------------------------



Fossils of first bird beak discovered, a key clue in how birds evolved from dinosaurs

2018

https://www.usatoday.com/story/news/2018/05/03/fossils-first-bird-beak-dinosaurs/576762002/



-----------------------------------------------



Evolution and taxonomy of Ice Age deer

https://www.nhm.ac.uk/our-science/our-work/origins-evolution-and-futures/evolution-taxonomy-ice-age-deer.html

This project aims to reconstruct the relationships between deer populations that lived in Europe between 2.5 million years ago and the present. It is improving our understanding of current global diversity and the distribution of deer.

Sharp climatic oscillations during the ice ages led to deer evolving and differentiating very rapidly, producing a high number of species and subspecies.

Due to their dynamic evolution and abundance as fossils, deer have been the focus of intense research. There is no agreement, however, on the validity of individual species and subspecies and their inter-relationships.



---------------------------------------------------



Extinct deer-like creature sheds light on biodiversity

https://www.floridamuseum.ufl.edu/science/extinct-deer-like-creature-sheds-light-on-biodiversity/



----------------------------------------------------



Bony labyrinth morphology clarifies the origin and evolution of deer

13 October 2017

https://www.nature.com/articles/s41598-017-12848-9



----------------------------------------------------



Evolution of ruminant headgear: a review

2011

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151718/



----------------------------------------------------



The Case of the Irish Elk

https://ucmp.berkeley.edu/mammal/artio/irishelk.html



----------------------------------------------------



The giant elk mystery

2003

https://www.irishtimes.com/news/the-giant-elk-mystery-1.375699



----------------------------------------------------



Skeleton of the giant deer Megaloceros giganteus giganteus (Blumenbach, 1803) (Mammalia, Artiodactyla) from the Irtysh Region near Pavlodar

08 October 2014

https://link.springer.com/article/10.1134/S0031030114050104



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Antlers Are Miraculous Face Organs That Could Benefit Human Health

June 12, 2017

There’s so much more to deer antlers than fighting and impressing the ladies

https://www.smithsonianmag.com/science-nature/antlers-are-miraculous-face-organs-could-benefit-human-health-180963635/



----------------------------------------------------



This Strange Buck Was a Throwback to Extinct Whitetail Ancestors

June 12, 2019

https://www.qdma.com/this-strange-buck-was-a-throwback-to-extinct-whitetail-ancestors/



----------------------------------------------------



Morphometrical relationships between South-east Asian deer (Cervidae, tribe Cervini): evolutionary and biogeographic implications

June 2004

https://www.cambridge.org/core/journals/journal-of-zoology/article/morphometrical-relationships-between-southeast-asian-deer-cervidae-tribe-cervini-evolutionary-and-biogeographic-implications/DE1A83CD6FAB0F527A81AFCEB8A69E16



----------------------------------------------------



VARIATION IN SKULL MORPHOLOGY OF ROE DEER (CAPREOLUS CAPREOLUS) IN WESTERN AND CENTRAL EUROPE

https://academic.oup.com/jmammal/article/79/1/131/841874



----------------------------------------------------



Vampire Deer: Why Some Deer Have Fangs

https://untamedscience.com/biodiversity/vampire-deer/

The (Evolutionary) Road Less Travelled

Why don’t larger deer come equipped with fangs? The answer lies in the distant past. When deer were first evolving, they were tiny creatures that had both fangs and antlers; it was actually their default mode. In fact, they looked pretty much like the fanged deer of today. These guys haven’t changed much through the course of history.


---------------------------------------------------


Why Do Deer Lose Their Antlers?

https://sciencing.com/do-deer-lose-antlers-5154554.html


----------------------------------------------------


Most weird deer antlers are not caused by genetics


2018


Most often it's injury that causes weird deer antlers. These injuries can range from leg wounds to tears in the antler velvet.


https://www.grandviewoutdoors.com/big-game-hunting/deer/most-weird-deer-antlers-are-not-caused-by-genetics


----------------------------------------------------


 Frontal sinuses and head-butting in goats: a finite element analysis

2008


https://jeb.biologists.org/content/211/19/3085


------------------------------------------------------------


The Evolutionary Significance of Mountain Sheep Horns

Dec, 1966


https://www.jstor.org/stable/2406590?origin=crossref&seq=1

------------------------------------------------------------


The Evolution of Horn-Like Organs

1965


https://www.jstor.org/stable/4533157?seq=1

------------------------------------------------------------

Adaptation to milk drinking and evolution oflactase persistence in pastoralist goat herdersin central-northern Chile


June 2014

https://discovery.ucl.ac.uk/id/eprint/1458425/3/NA_MONTALVA_RIVERA.pdf


-----------------------------------------------------------


Here’s why goats have those freaky eyes

https://www.washingtonpost.com/news/speaking-of-science/wp/2015/08/10/heres-why-goats-have-those-freaky-eyes/


------------------------------------------------------------


Horses, goats, and poison ivy - what they have to do with each other!

Some goats LOVE TO EAT POISON IVY.  There are also many goat loaning services that will deliver goats to you for brush clearing.  YES, that's a real business.  Why didn't I think of that!? They will eat the leaves, but not the roots, so it’s likely that the leaves will grow back… but - over time the plant will not be able to survive if it’s continually eaten.

https://www.proequinegrooms.com/tips/barn-management/horses-goats-and-poison-ivy-all-of-the-details



---------------------------------------------------------




Distinctive features of Ovis aries and Capra hircus petrosal parts of temporal bone: Applications of the features to the distinction of some other Caprinae (Capra ibex, Rupicapra rupicapra)

https://journals.openedition.org/paleo/2862



----------------------------------------------------


Evolution of the horse

https://www.britannica.com/animal/horse/Evolution-of-the-horse


----------------------------------------------------


Evolution of the horse

https://en.wikipedia.org/wiki/Evolution_of_the_horse


-----------------------------------------


ONTOGENY AND PHYLOGENY IN HORSE SKULL EVOLUTION

1983

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1558-5646.1984.tb00254.x


-----------------------------------------


Evolution in the Horse's Skull

03 October 1942

https://www.nature.com/articles/150402a0


-----------------------------------------


Shape variation and modularity of skull and teeth in domesticated horses and wild equids

2018

https://frontiersinzoology.biomedcentral.com/articles/10.1186/s12983-018-0258-9


-----------------------------------------


Allometry and reorganization in horse skull proportions

1983

https://www.ncbi.nlm.nih.gov/pubmed/17811522


-----------------------------------------


Horse Evolution Over 55 Million Years

The Evolution of the Horse's Foot

https://chem.tufts.edu/science/evolution/HorseEvolution.htm


-----------------------------------------



Horses, the Fossil Record, and Evolution

https://link.springer.com/chapter/10.1007/978-1-4613-0931-4_3

 


----------------------------------------



Ideas about fossil horses undergo evolution in thinking

August 1, 2005

https://www.floridamuseum.ufl.edu/science/ideas-about-fossil-horses-undergo-evolution-in-thinking/



-----------------------------------------


Why the long face? Comparative shape analysis of miniature, pony, and other horse skulls reveals changes in ontogenetic growth

2019

https://peerj.com/articles/7678/


-----------------------------------------


Evolution of Earliest Horses Driven by Climate Change

2012

https://www.nsf.gov/news/news_summ.jsp?cntn_id=123252


-----------------------------------------



 The Giant Camels of the Prehistoric High Arctic

https://www.nationalgeographic.com/science/phenomena/2013/03/05/the-giant-camels-of-the-prehistoric-high-arctic/


---------------------------------------------------------


Ancient Whales' Hearing Was Like Hippos And Camels, Fossils Show

Jun 8, 2017

https://www.forbes.com/sites/grrlscientist/2017/06/08/ancient-whales-hearing-was-like-their-land-based-relatives-fossils-show/#3989b655131a


----------------------------------------------------------


Complete camel skeleton unearthed in Austria

2015

https://phys.org/news/2015-04-camel-skeleton-unearthed-austria.html


---------------------------------------------------------


Late Pleistocene horse and camel hunting at the southern margin of the ice-free corridor: Reassessing the age of Wally’s Beach, Canada

April 7, 2015


https://www.pnas.org/content/112/14/4263


-----------------------------------------



The old and new faces of morphology: the legacy of D'Arcy Thompson's ‘theory of transformations' and ‘laws of growth'

2017







https://dev.biologists.org/content/144/23/4284.figures-only


------------------------------------------


Carnivora Skull Shape Depends on More Than Just Diet

Feb 7, 2018

https://www.amnh.org/explore/news-blogs/news-posts/carnivora-skull-shape-depends-on-more-than-just-diet


------------------------------------------


Functional Relationship between Skull Form and Feeding Mechanics in Sphenodon, and Implications for Diapsid Skull Development

2011

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029804


------------------------------------------



Evolutionary and biogeographical implications of variation in skull morphology of raccoon dogs (Nyctereutes procyonoides, Mammalia: Carnivora)

2015

https://onlinelibrary.wiley.com/doi/abs/10.1111/bij.12629



-----------------------------------------



Whales may have evolved from raccoon-sized creature

2007

https://www.reuters.com/article/us-whales-fossil/whales-may-have-evolved-from-raccoon-sized-creature-idUSN1963835720071220


----------------------------------------------------



 SKULLS  of the  MAMMALS in TASMANIA










https://www.bien.org.au/wp-content/uploads/2017/04/Skulls-of-Tasmania-Rainbird.pdf



---------------------------------------------------



 Functional Evolution of the Feeding System in Rodents

2012

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338682/



---------------------------------------------------


A phylogenomic rodent tree reveals the repeated evolution of masseter architectures

08 May 2019

https://royalsocietypublishing.org/doi/full/10.1098/rspb.2019.0672


----------------------------------------------------


Diet, bite force and skull morphology in the generalist rodent morphotype

2016

https://onlinelibrary.wiley.com/doi/10.1111/jeb.12937


----------------------------------------------------


Rodent of unusual size discovered

2008

https://www.nature.com/articles/news.2008.441


----------------------------------------------------


Getting a head in hard soils: Convergent skull evolution and divergent allometric patterns explain shape variation in a highly diverse genus of pocket gophers (Thomomys)

2016

https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-016-0782-1


---------------------------------------------------


A phylogenetic test of adaptation to deserts and aridity in skull and dental morphology across rodents

2018


https://academic.oup.com/jmammal/article/99/5/1197/5069531



----------------------------------------------------


Life in Burrows Channelled the Morphological Evolution of the Skull in Rodents: the Case of African Mole-Rats (Bathyergidae, Rodentia)

19 August 2015

https://link.springer.com/article/10.1007/s10914-015-9305-x


----------------------------------------------------


Scientists ‘replay’ evolution with mouse teeth

July 31st, 2014

How teeth change

Evans says the evolution of rodents shown in the experiment also applies to carnivorous animals. He examined how tooth complexity changed in these mammal groups.

“Amazingly, we found that the features that we could control in mice vary in the same way in carnivorous mammals like the lion, wolf, and bear—the same rules apply to cats and mice,” he says.

The next phase of research will investigate other mechanisms that influence tooth development, and apply these results to more accurately reconstruct the history of mammals.

https://www.futurity.org/mice-teeth-evolution-740292/


----------------------------------------------------


Research shows rats have best bite of rodent world

April 27, 2012

https://phys.org/news/2012-04-rats-rodent-world.html


----------------------------------------------------


Do Mice Get Cavities? All About Mammal Teeth

2017

https://www.adirondackalmanack.com/2017/05/mammal-teeth.html


---------------------------------------------------


 Is Evolution of Blind Mole Rats Determined by Climate Oscillations?

January 9, 2012

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030043


------------------------------------------------------------------------------


 Mammals First Evolved Big Brains for Better Sense of Smell

May 19, 2011

http://www.jsg.utexas.edu/news/2011/05/mammals-first-evolved-big-brains-for-better-sense-of-smell/


------------------------------------------------------------------------------



 Her Incredible Sense Of Smell Is Helping Scientists Find New Ways To Diagnose Disease

March 23, 2020


https://www.npr.org/sections/health-shots/2020/03/23/820274501/her-incredible-sense-of-smell-is-helping-scientists-find-new-ways-to-diagnose-di?utm_source=pocket-newtab


--------------------------------------------------


Where Pain Lives

Fixing chronic back pain is possible only when patients understand how much it is produced by the brain, not the spine.

https://getpocket.com/explore/item/where-pain-lives?utm_source=pocket-newtab


------------------------------------------------------------------------------ 




This Wild Pig Has Fangs That Can Pierce Its Own Skull


Feb 3, 2017


https://www.youtube.com/watch?v=2D-7zgw1Lq0



-------------------------------



Similar rates of morphological evolution in domesticated and wild pigs and dogs


2018


https://frontiersinzoology.biomedcentral.com/articles/10.1186/s12983-018-0265-x



-------------------------------------------------------------------------------


Review: Your Inner Reptile

April 19, 2014













(Mammals have three tiny bones in their middle ear, though they often are not preserved in the fossil record. Reptiles—like the “non-mammalian amniote” in the drawing—have only one ear bone but have jaws made of multiple bones. Evolutionists claim that two jaw bones in reptiles got smaller over millions of years, migrated to the ear, and evolved in the precisely connected trio of bones found in mammalian ears. This belief is based on an evolutionary desire to “connect the dots” on the tree of life, as reptiles with variations in their jaws are still reptiles, not transitional forms. Image: Philcha, Wikipedia).


https://answersingenesis.org/reviews/tv/review-your-inner-reptile/


------------------------------------------------------------------------------


Evolutionary morphology of the rabbit skull

2016

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036099/


---------------------------------------------------------------------

Earliest Rabbit Fossil Found, Suggests Modern Mammal Group Emerged As Dinosaurs Faced Extinction

Feb 5, 2006

https://www.amnh.org/research/science-news/2006/earliest-rabbit-fossil-found-suggests-modern-mammal-group-emerged-as-dinosaurs-faced-extinction


-----------------------------------------------------------------------


Rabbit-proof hoof: Ungulates suppressed lagomorph evolution

https://worldlagomorphsociety.org//News/Details/c7a8a957-e233-4ce3-825d-daef59626aae


-----------------------------------------------------------------------


Giant Rabbit Fossil Found: Biggest Bunny Was "Roly-Poly"

https://www.nationalgeographic.com/news/2011/3/110323-giant-rabbit-minorca-biggest-bunny-science-nuralagus-rex-largest/

----------------------------------------------------------------------

Resurrecting Darwin’s ‘Lop-eared’ Rabbits

August 22, 2016

http://thescienceexplorer.com/nature/resurrecting-darwin-s-lop-eared-rabbits

----------------------------------------------------------------------


Cranial  Specialization  and  Locomotor  Habit in  the  Lagomorpha1

1989

https://academic.oup.com/icb/article/29/1/303/184455

---------------------------------------------------------------------


Changes in brain architecture are consistent with altered fear processing in domestic rabbits

https://www.pnas.org/content/115/28/7380


----------------------------------------------------------------------


Armadillo and rabbit genes reveal how pregnancy evolved

 09 January 2018

Inflammation engulfs a fetus in its first days, but small changes to that attack enables the embryo to implant in the uterus.


https://www.nature.com/articles/d41586-018-00341-w


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Rodent-like Mammal Shakes the Evolutionary Tree

2014

The lucky discovery of a 5-inch long skull belonging to an extinct 20-pound Mesozoic groundhog-like animal threatens to rewrite the evolutionary history of mammals. Dubbed Vintana sertichi (because “vintana” is Malagasy for “lucky”), the skull (minus its lower jaw) was found fossilized in Madagascar with lots of fish in a large block of sandstone dated late in the “age of dinosaurs.” Believed by evolutionists to have inhabited a large southern land mass known as Gondwana 66 million years ago, it is the first good representative of the gondwanatherians, previously known only from isolated teeth and jaw fragments.

https://answersingenesis.org/mammals/rodent-like-mammal-shakes-the-evolutionary-tree/


----------------------------------------------------


 Koalas aren’t primates, but they move like monkeys in trees


Climbing high in tree branches, the iconic marsupial is Australia’s answer to primates

https://www.sciencenews.org/article/koalas-are-not-primates-but-they-move-like-monkeys-trees


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A Creepy Virus is forcing koalas to evolve before our eyes

10.10.2019

There's an invader in their DNA.


https://www.inverse.com/article/59977-koala-retrovirus-is-forcing-it-to-evolve


---------------------------------------------------------------------------


Why Are There So Many Marsupials in Australia?

March 03, 2019

https://www.livescience.com/64897-why-marsupials-in-australia.html


----------------------------------------------------------------------




Cranial anatomy of Oligo-Miocene koalas(Diprotodontia: Phascolarctidae): stages in theevolution of an extreme leaf-eating specialization

https://www.tandfonline.com/doi/pdf/10.1671/039.029.0412



----------------------------------------------------


Bipedalism left its mark on human skull: Kangaroos and upright rodents show same signs

https://www.earthmagazine.org/article/bipedalism-left-its-mark-human-skull-kangaroos-and-upright-rodents-show-same-signs-0


----------------------------------------------------




Oldest cingulate skulls provide congruence between morphological and molecular scenarios of armadillo evolution

02 February 2011

https://royalsocietypublishing.org/doi/10.1098/rspb.2010.2443



---------------------------------------------------------------------




Beyond the carapace: skull shape variation and morphological systematics of long-nosed armadillos (genus Dasypus)

August 15, 2017

https://peerj.com/articles/3650/



---------------------------------------------------------------------


Taxonomic revision of the long-nosed armadillos, Genus Dasypus Linnaeus, 1758 (Mammalia, Cingulata)

April 6, 2018

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0195084


----------------------------------------------------------------------


Evolution of the axial skeleton in armadillos (Mammalia, Dasypodidae)

July 2010

https://www.sciencedirect.com/science/article/abs/pii/S1616504709000457


----------------------------------------------------------------------


The masticatory apparatus of the armadillo Eutatus (Mammalia, Cingulata) and some allied genera: paleobiology and evolution

1998

https://www.cambridge.org/core/journals/paleobiology/article/masticatory-apparatus-of-the-armadillo-eutatus-mammalia-cingulata-and-some-allied-genera-paleobiology-and-evolution/AC797B4A88AE0B26FE9CCE1A45BD3184



----------------------------------------------------------------------


The Glyptodon Was A Prehistoric Armadillo So Big That Early Humans Used Its Shells For Shelters

November 19, 2018

https://allthatsinteresting.com/glyptodon


----------------------------------------------------------------------


A new fairy armadillo (Cingulata, Chlamyphorinae) from the upper Miocene of Argentina: first fossil record of the most enigmatic Xenarthra


2019

https://www.tandfonline.com/doi/full/10.1080/02724634.2019.1716778



---------------------------------------------------------------------


Evolution of post-weaning skull ontogeny in New World opossums (Didelphidae)

25 June 2018

https://link.springer.com/article/10.1007/s13127-018-0369-3


---------------------------------------------------------------------


Ancient origins of modern opossum revealed

December 17, 2009

https://www.sciencedaily.com/releases/2009/12/091215202320.htm


---------------------------------------------------------------------


Cranial Anatomy of the Earliest Marsupials and the Origin of Opossums

December 16, 2009

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008278


--------------------------------------------------------------------


The Opossum genome reveals further evidence for regulatory evolution in mammalian diversification


2007

https://genomebiology.biomedcentral.com/articles/10.1186/gb-2007-8-8-223


---------------------------------------------------------------------


CRANIOFACIAL HETEROCHRONY AND SEXUAL DIMORPHISM IN THE SHORT-TAILED OPOSSUM (MONODELPHIS DOMESTICA)

https://academic.oup.com/jmammal/article-pdf/77/4/992/2768789/77-4-992.pdf

 

---------------------------------------------------------------------


The evolution of active vibrissal sensing in mammals: evidence from vibrissal musculature and function in the marsupial opossum Monodelphis domestica

2013

https://jeb.biologists.org/content/216/18/3483


--------------------------------------------------------------------


Zoologger: The pint-sized sabre-toothed opossum

25 July 2013

https://www.newscientist.com/article/dn23933-zoologger-the-pint-sized-sabre-toothed-opossum/


--------------------------------------------------------------------


Evolution of the Genotype-to-Phenotype Map and the Cost of Pleiotropy in Mammals

2016

https://www.genetics.org/content/204/4/1601


--------------------------------------------------------------------


In the developing ears of opossums, echoes of evolutionary history

February 22, 2017

https://www.igb.illinois.edu/article/developing-ears-opossums-echoes-evolutionary-history

---------------------------------------------------------------------

 

 What your earwax says about your ancestry

February 24, 2014


https://www.sciencenews.org/blog/gory-details/what-your-earwax-says-about-your-ancestry


-------------------------------


Digging For Gold: Study Says Your Race Determines Your Earwax Scent

2014

https://www.npr.org/sections/codeswitch/2014/03/20/283101999/digging-for-gold-study-says-your-race-determines-your-earwax-scent


--------------------------------------------------------------------

 

Ears: Do Their Design, Size and Shape Matter?

November 19, 2015

https://www.scientificamerican.com/article/ears-do-their-design-size-and-shape-matter/


--------------------------------------------------------------------


The 7 Types of Earlobes and the Secrets They Reveal About Your Personailty

20 February 2019

https://www.cosmopolitan.in/life/features/a16961/7-types-earlobes-and-secrets-they-reveal-about-your-personailty

 

--------------------------------------------------------------------

 

 
Genetics of Earlobes

 

2021 


https://www.news-medical.net/health/Genetics-of-Earlobes.aspx

 

Similar to the human eyes, nose, and lips, the earlobes also have unique features. Although the human ears appear similar, minor structural differences make each ear different from the other.

 

The primary form of the gene that determines the shape of the earlobe is known as an allele. An allele is a gene that is found at a specific position on a chromosome. It has been established that all genes in our body have two copies, one from each parent.

 

Types of earlobes

 

An earlobe is made up of connective tissues combined with a mixture of areola tissues and fat cells. Earlobes have a good blood supply, which helps in keeping them warm and maintaining balance. There are two primary types of earlobes found in humans, which include free earlobes and attached earlobes.

 

 

Free earlobes

 

Free earlobes are the most common form of ear lobes in humans. This type of earlobe is often large and hangs below the point of attachment to the head. This happens due to the influence of a dominant allele. If the parents' genes express the dominant allele, the child will be born with free earlobes.

In most cases, the allele is regnant to the free lobes compared to attached lobes. The free earlobe parents can also give birth to an attached earlobe child, depending on the allele gene's reaction. If parents with free earlobes give birth to a baby with attached earlobes, both of them had both a copy of the dominant and recessive allele.

 

 

Attached earlobes

 

Attached earlobes are not rare but are also not commonly found. Earlobes of such type are small in size and are attached directly to the side of the head. This kind of lobe's structural formation is due to the absence of the dominant allele in the chromosomes. The recessive allele is expressed to form an attached earlobe. Parents with attached earlobes will not necessarily give birth only to children with attached earlobes.

Traits are the major factors that result from chromosome pairs, which determine one’s overall physical appearance. When alleles combine, some exert a ‘stronger’ influence as compared to others. The stronger allele is responsible for the dominant traits.

If the dominant allele fails to show its presence, the recessive allele will be expressed. These are known as recessive traits.

Although the traits vary, the size of the earlobes for both the traits remains the same. An average man’s ear measures about 6 centimeters (cm), while for a woman, it is about 5 cm, in which the earlobe size measures about 2 cm.

 

 

Genetic diseases and earlobes

 

Genetic conditions play an important role in the birth of a human being. People born with abnormal growth of organs are considered to be affected by the traits before their birth.

Birth disorders may be minor or severe and may occur at any stage during pregnancy. Most disorders affect the baby while in the womb, before the formation of the organs; however, not all genetic defects are caused by the parents' transfer of genes. In many cases, the baby may be born with genetic disorders that the parent’s gene does not contain. Some defects are considered to be harmless, while some may require prolonged medical treatment.

The major conditions that cause irregular or abnormal growth and can subsequently affect the appearance of the earlobes include Down's syndrome, Turner syndrome, and Beckwith-Wiedemann syndrome (BWS).

 

 

Down’s syndrome

 

Down’s syndrome is a condition caused by the presence of an extra chromosome. Generally, a person has 46 chromosomes; however, people with Down’s syndrome have 47 chromosomes. The extra chromosome may influence the growth and development of the body.

People with this syndrome tend to have large ears, a small neck, and a flat face. Down’s syndrome cannot be cured, but the affected person can grow healthily without any trouble.

 

 

Turner syndrome

 

Only females are affected by Turner syndrome, which is a rare condition in which there is a lack of one or part of the second X chromosome. It is assumed that this chromosomal abnormality occurs due to an error in the parent’s reproductive cell. A person with this syndrome will have abnormal ears, eyes, skeletal structure, and even kidney abnormalities.

 

 

BWS

 

BWS is described as the modification that occurs in the genes of chromosome 11. BWS is an excessive growth disorder indicated by large body parts, enlarged tongue, earlobe creases, etc.

The earlobe crease is a wrinkle in the earlobe, which occurs due to the trait that was passed genetically by the family. The wrinkle is created when the flow of blood is decreased in the ear. Currently, there is no method of treatment identified to cure ear creases.

 

 

--------------------------------------------------------------------

 

Ear lobe crease: a marker of coronary artery disease?

2015

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697048/

 

--------------------------------------------------------------------

 

 

Earlobe Type, Race, and Age: Effects on Earlobe Creasing

August 1983

https://agsjournals.onlinelibrary.wiley.com/doi/abs/10.1111/j.1532-5415.1983.tb05121.x

 

Abstract

 

There has been much discussion of the utility and validity of the earlobe crease as a warning sign of cardiovascular disease. The authors postulated that the mixed findings were due to the neglect of three variables: age, race, and earlobe shape. Age and earlobe shape were studied in 324 healthy adult subjects from three racial groups: southwestern Alaskan Eskimos (70), Navajos (167), and whites (87). It was found that creases develop with age in healthy adults, that creasing is related to earlobe shape, that the age of onset of creasing varies according to race, and that the frequencies of occurrence of different earlobe shapes differ by race. Future studies of earlobe creases should therefore include the variables of age, race, and earlobe shape.

 

 

--------------------------------------------------------------------

 

Reevaluation of the earlobe types in Koreans

2018

https://www.sciencedirect.com/science/article/abs/pii/S0018442X18300611

Abstract

The shape of the earlobes has a variety of genetic significance. This study analyzed the frequencies of the earlobe shapes in the Korean population. Data were collected on randomly selected 500 males and 500 females in Daegu Metropolitan City, with all participant ages being in their twenties. Obtuse angled earlobes accounted for 41.2% of the earlobes observed, while acute angled earlobes prevalence was calculated at 38.8% and right angled earlobe was 20.0% of the total (sexes combined). In men, the acute angled earlobe was the most frequent type (43.0%), while the obtuse angled earlobe was the most frequent type in females (45.2%). These differences were statistically significant (p = 0.015). Overall, attached type earlobe (61.2%) was more frequent than free type earlobe. The attached type earlobe was more common in both sex groups (57.0% in male and 65.4% in female), and the proportion was significantly higher for females (p = 0.006). In conclusion, the findings in this study suggest that the attached earlobe type is the most common among Koreans, and the proportion of earlobe types among males and females is significantly different. Further studies are needed to understand the genetic background of earlobe types among Koreans. 

 

--------------------------------------------------------------------

 


What race has attached earlobes?

April 14, 2021

https://answerstoall.com/technology/what-race-has-attached-earlobes/


--------------------------------------------------------------------


Connected Earlobes?

https://www.stormfront.org/forum/t526780/


--------------------------------------------------------------------


Attached earlobe: The myth

https://udel.edu/~mcdonald/mythearlobe.html

 

 

--------------------------------------------------------------------




Paleogene Xenarthra and the evolution of South American mammals


Cranial anatomy of Oligo-Miocene koalas(Diprotodontia: Phascolarctidae): stages in the evolution of an extreme leaf-eating specialization

 02 Aug 2010

https://www.tandfonline.com/doi/pdf/10.1671/039.029.0412




------------------------------------------------------------------------



Paleontological and developmental evidence resolve the homology and dual embryonic origin of a mammalian skull bone, the interparietal

2012

https://www.pnas.org/content/109/35/14075



-----------------------------------------------------------------------



Baby Reptile Fossils in Arizona Fill Gap in Evolution of Mammal Childbirth


sep 5, 2018


https://www.azpm.org/s/59797-baby-reptile-fossils-in-arizona-fill-gap-in-evolution-of-mammal-childbirth/


------------------------------------------------------------------


Rostro-dorsal and rostro-lateral skull morphologic variability in three age-groups of the Egyptian mongoose (Herpestes ichneumon) (Linnaeus, 1758): implications of certain orbital parameters — angular geometric approach

https://journals.viamedica.pl/folia_morphologica/article/download/FM.a2016.0022/36844


----------------------------------------------------



Deformed Skull Morphology Is Caused by the Combined Effects of the Maldevelopment of Calvarias, Cranial Base and Brain in FGFR2-P253R Mice Mimicking Human Apert Syndrome

2017

https://www.ijbs.com/v13p0032.htm


----------------------------------------------------


 The giant fossil mammals that inspired Charles Darwin's theory of evolution

9 April 2018

https://www.nhm.ac.uk/discover/news/2018/april/giant-fossil-mammals-inspired-charles-darwin-theory-evolution.html


----------------------------------------------------

Bull-Size Rodent Discovered—Biggest Yet

The prehistoric 'rat' had huge teeth, a new study says, and the animal likely competed with saber-toothed cats and giant, flightless, meat-eating birds.

https://www.nationalgeographic.com/animals/2008/01/south-america-large-rodent-discovery-animals/

---------------------------------------------------


Andrewsarchus, "Superb Skull of a Gigantic Beast"

Jul 3, 2013

https://www.amnh.org/explore/news-blogs/on-exhibit-posts/andrewsarchus


----------------------------------------------------


When Animals Shrink to Minature Form

http://www.bbc.com/earth/story/20151021-when-animals-shrink-to-miniature-form


----------------------------------------------------


 Dwarfism in insular sloths: biogeography, selection, and evolutionary rate

JUNE 2002

http://www.paxtag.org/wp-content/uploads/2015/07/Anderson-2002.-Dwarfism-In-Insular-Sloths-biogeography-selection-and-evolutionary-rate.pdf


----------------------------------------------------


The hidden teeth of sloths: evolutionary vestiges and the development of a simplified dentition

2016

https://www.nature.com/articles/srep27763


------------------------------------------


Darwin's giant ground sloth skull pieced together and scanned for the first time

23 November 2018

https://www.nhm.ac.uk/discover/news/2018/november/darwins-giant-ground-sloth-skull-pieced-together-and-scanned.html


------------------------------------------


Patterns of Morphological Variation of Extant Sloth Skulls and their Implication for Future Conservation Efforts

25 April 2014

https://anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/ar.22916


------------------------------------------


Evolutionary adaptation to aquatic lifestyle in extinct sloths can lead to systemic alteration of bone structure

2018

https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2018.0270


------------------------------------------



The ground sloth Megatherium americanum: Skull shape, bite forces, and diet


2001

https://www.app.pan.pl/archive/published/app46/app46-173.pdf



------------------------------------------



Evolution of body size in anteaters and sloths (Xenarthra, Pilosa): phylogeny, metabolism, diet and substrate preferences

https://www.cambridge.org/core/journals/earth-and-environmental-science-transactions-of-royal-society-of-edinburgh/article/evolution-of-body-size-in-anteaters-and-sloths-xenarthra-pilosa-phylogeny-metabolism-diet-and-substrate-preferences/421A0CE4BDBEDA50117FC0AE9EED878C/core-reader


------------------------------------------


The evolution of armadillos, anteaters, and sloths depicted by nuclear and mitochondrial phylogenies: implications for the status of the enigmatic fossil Eurotamandua.

https://hal.archives-ouvertes.fr/halsde-00192975/document


------------------------------------------



 How the earliest mammals thrived alongside dinosaurs

23 October 2019

An explosion of fossil finds reveals that ancient mammals evolved a wide variety of adaptations allowing them to exploit the skies, rivers and underground lairs.

https://www.nature.com/articles/d41586-019-03170-7


-----------------------------------------



The giant sloths that lived in the sea

http://www.eartharchives.org/articles/the-giant-sloths-that-lived-in-the-sea/


------------------------------------------


27,000-year-old giant ground sloth tooth is like a climate time capsule

February 27, 2019

https://www.cnn.com/2019/02/27/world/giant-ground-sloth-fossil/index.html


------------------------------------------


The Evolution of Feeding Adaptations of the Aquatic Sloth Thalassocnus

2004

https://www.jstor.org/stable/4524727?seq=1


------------------------------------------


Musculoskeletal networks reveal topological disparity in mammalian neck evolution

2017

https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-017-1101-1



------------------------------------------


Chewing through the Miocene: an examination of the feeding musculature in the ground sloth Hapalops from South America (Mammalia: Pilosa)

https://f1000research.com/articles/3-86


 ----------------------------------------------


What a 20 million-year-old monkey skull reveals about the evolution of human brains

August 22, 2019

https://nypost.com/2019/08/22/what-a-20-million-year-old-monkey-skull-reveals-about-the-evolution-of-human-brains/


---------------------------------------------



Scientists use a 20-million-year-old skull of a newly discovered ancient human ancestor found in Chile to map out how the human brain evolved

21 August 2019


    Research was conducted on a fossil discovered high in the Andes mountains
    Brain enlargement happened repeatedly over time with occasional decreases
    It has long been thought that the brain size of anthropoid primates progressively
    Experts used scanning and digital reconstruction methods to analyse the skull
    Scientists also measured the eye socket and the opening to the optic canal

https://www.dailymail.co.uk/sciencetech/article-7380559/Ancient-skull-suggests-complex-brain-evolution-primates.html


---------------------------------------------



Two monkey teeth: the first monkey fossils found in Serbia. Predrag Radović, Author provided

October 21, 2019

Monkey fossils found in Serbia offer clues about life in a warmer world millions of years ago

https://theconversation.com/monkey-fossils-found-in-serbia-offer-clues-about-life-in-a-warmer-world-millions-of-years-ago-125420

 


---------------------------------------------


Macroevolution of Primate Skull Shape: Combining Geometric Morphometrics and Phylogenetic Comparative Methods

2018

https://dukespace.lib.duke.edu/dspace/handle/10161/17444



---------------------------------------------



Diurnality, Nocturnality, and the Evolution of Primate Visual Systems

2008

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajpa.20957


---------------------------------------------



Primitive Old World monkey from the earliest Miocene of Kenya and the evolution of cercopithecoid bilophodonty

2019

https://www.pnas.org/content/116/13/6051



---------------------------------------------



Skull of humankind's oldest-known ancestor discovered

2019

‘Iconic’ finding of 3.8m-year-old fossil in Ethiopia casts doubt on previous evolutionary theory

https://www.theguardian.com/science/2019/aug/28/skull-of-human-ancestor-aged-38m-years-discovered


---------------------------------------------



Fossil Reveals What Last Common Ancestor of Humans and Apes Looked Liked

August 10, 2017

The 13-million-year-old infant skull may have resembled a baby gibbon

https://www.scientificamerican.com/article/fossil-reveals-what-last-common-ancestor-of-humans-and-apes-looked-liked/



---------------------------------------------



Evolution and development of the strepsirrhine primate skull

https://www.zora.uzh.ch/id/eprint/16970/


---------------------------------------------

 Sexual behaviour and evolution of sexual dimorphism in body  size in Jaera (Isopoda  Asellota)

1979

https://decapoda.nhm.org/pdfs/23872/23872.pdf

---------------------------------------------


Sexual Dimorphism in Primate Evolution

2001

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajpa.10011


---------------------------------------------


Homo Erectus Was Sexually Dimorphic, New Evidence Shows

Mar 04, 2020

Experts explain to Haaretz how mere fragments of two skulls discovered in Ethiopia can be distinguished as male and female, and did it really use both crude and clever tools at the same time?

https://www.haaretz.com/archaeology/.premium-homo-erectus-was-sexually-dimorphic-new-evidence-shows-1.8627492


---------------------------------------------


GENETIC VARIATION IN BABOON CRANIOFACIAL SEXUAL DIMORPHISM

2010

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836714/


---------------------------------------------


A missing piece of the Papiopuzzle: Gorongosa baboon phenostructure and intrageneric relationships

2019

https://www.gorongosa.org/sites/default/files/research/a_missing_piece_of_the_papio_puzzle.pdf


---------------------------------------------


Skull of Earliest Baboon Discovered

August 21, 2015

https://www.livescience.com/51937-earliest-baboon-fossil.html


---------------------------------------------


Baboon bone found in famous Lucy skeleton

10 April 2015

https://www.newscientist.com/article/dn27325-baboon-bone-found-in-famous-lucy-skeleton/


---------------------------------------------


Taung Child

https://en.wikipedia.org/wiki/Taung_Child

The Taung Child (or Taung Baby) is the fossilised skull of a young Australopithecus africanus. It was discovered in 1924 by quarrymen working for the Northern Lime Company in Taung, South Africa. Raymond Dart described it as a new species in the journal Nature in 1925.

The Taung skull is in repository at the University of Witwatersrand. Dean Falk, a specialist in brain evolution, has called it "the most important anthropological fossil of the twentieth century."



---------------------------------------------


Making Space for Permanent Molars in Growing Baboon (Papio anubis) and Great Ape (Pan paniscus and P. troglodytes) Mandibles: Possible Ontogenetic Strategies and Solutions

2011

https://www.hindawi.com/journals/ari/2011/484607/


---------------------------------------------


First skull of Antillothrix bernensis, an extinct relict monkey from the Dominican Republic

2010

https://royalsocietypublishing.org/doi/full/10.1098/rspb.2010.1249


---------------------------------------------




Scientists create ‘virtual brains’ from tiny primate skulls

2016

https://www.futurity.org/primates-brains-evolution-1224282-2/



---------------------------------------------


 Monkeys and humans more closely related, new species disovery suggests

July 14, 2010

Humans and monkeys may have diverged more recently than scientists have thought, a partial primate skull discovered in Saudi Arabia suggests.

https://www.csmonitor.com/Science/2010/0714/Monkeys-and-humans-more-closely-related-new-species-disovery-suggests


---------------------------------------------


Dian Fossey’s Gorilla Skulls Are Scientific Treasures and a Symbol of Her Fight

March 17, 2017

At a new Smithsonian exhibition, the skulls of “Limbo” and “Green Lady” have a story to tell


https://www.smithsonianmag.com/smithsonian-institution/dian-fosseys-gorilla-skulls-are-scientific-treasures-and-symbol-her-fight-180962564/


---------------------------------------------


Gorilla-like anatomy on Australopithecus afarensis mandibles suggests Au. afarensis link to robust australopiths

2007

https://www.pnas.org/content/104/16/6568


---------------------------------------------


Sagittal Crest of the Skull

https://carta.anthropogeny.org/moca/topics/sagittal-crest-skull


---------------------------------------------


Unique human orbital morphology compared with that of apes

2015

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480145/


---------------------------------------------


PATTERN OF CRANIAL ONTOGENY IN POPULATIONS OF GORILLA AND PAN

June 2018

https://conservancy.umn.edu/bitstream/handle/11299/200300/Massey_umn_0130E_19416.pdf?sequence=1&isAllowed=y


---------------------------------------------


Great ape brains have a feature that we thought was unique to humans

14 February 2020

https://www.newscientist.com/article/2233798-great-ape-brains-have-a-feature-that-we-thought-was-unique-to-humans/


---------------------------------------------


Ancient "Nutcracker Man" Challenges Ideas on Evolution of Human Diet

2008

The researchers examined the teeth of Paranthropus boisei, an ancient hominin that lived between 2.3 and 1.2 million years ago and is known popularly as the "Nutcracker Man" because it has the biggest, flattest cheek teeth and the thickest enamel of any known human ancestor.

"Ungar and colleagues' work on Paranthropus boisei diet is extremely important," says Joanna Lambert, physical anthropology program director at NSF. "Understanding what and how early hominins ate sheds light not only onto the feeding biology of our fossil ancestors, but also onto the very evolution of our own species."

Scientists long have believed that P. boisei fed on nuts and seeds or roots and tubers found in the savannas throughout eastern Africa because the teeth, cranium and mandible appear to be built for chewing and crunching hard objects.

https://www.nsf.gov/news/news_summ.jsp?cntn_id=111457



---------------------------------------------


A rare find: Skull of a juvenile ape 6 million years old unearthed

2013

 An extremely rare juvenile skull of an extinct ape has now been revealed from China, findings that suggest a very diverse group of apes once lived in Southeast Asia, researchers say.

Apes, which include gorillas, chimpanzees and orangutans, are the closest living relatives of humanity. They once inhabited most of the Old World, including large portions of Europe and Asia, and a much larger swath of Africa than they do at present.

A critical time in the evolution of humans and their ape relatives was the late Miocene Epoch about 5 million to 11 million years ago. Near the end of the Miocene, apes had become extinct in most of Eurasia.

https://www.nbcnews.com/sciencemain/rare-find-skull-juvenile-ape-6-million-years-old-unearthed-8C11122570


---------------------------------------------



Ancient skull belonged to a cousin of the ape common ancestor

9 August 2017

https://www.newscientist.com/article/2143384-ancient-skull-belonged-to-a-cousin-of-the-ape-common-ancestor/



---------------------------------------------------------------


Anthropologist Adrienne Zihlman publishes 450-page opus on ape anatomy and evolution

September 24, 2019

https://news.ucsc.edu/2019/09/zihlman-anatomy.html


---------------------------------------------------------------




Australopithecines: Ancestors of the African Apes?

(1994)

https://link.springer.com/article/10.1007/BF02437259



------------------------------------------------------------------



 5 Amazing Finds Beneath the Sands of the Sahara

2016

https://www.youtube.com/watch?v=SpSI-dsEk3k



3:50 - Skeletons of Niger

The skulls of Kiffians were darker and had larger eye sockets than Tenerians, the bones of Kiffians were denser and more rigid.









-----------------------------------------------------------------


Stock Photo - The human skeleton as compared to a gorilla skeleton

https://www.pinterest.com/pin/380202393523814562/


-----------------------------------------------------------------


Lower Ilium Evolution in Apes and Hominins

https://anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/ar.23545


-----------------------------------------------------------------


An Inquiry Safari: What Can We Learn From Skulls?

2008

https://evolution-outreach.biomedcentral.com/articles/10.1007/s12052-007-0026-3


-----------------------------------------------------------------


Measure, Then Show: Grasping Human Evolution Through an Inquiry-Based, Data-driven Hominin Skulls Lab

2016

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160054


----------------------------------------------------------------


Chimps, Humans, and Monkeys: What’s the Difference?

2018

https://news.janegoodall.org/2018/06/27/chimps-humans-monkeys-whats-difference/


---------------------------------------------------------------


How smart were our ancestors? Turns out the answer isn’t in brain size, but blood flow

January 26, 2020

https://theconversation.com/how-smart-were-our-ancestors-turns-out-the-answer-isnt-in-brain-size-but-blood-flow-130387



---------------------------------------------------------------



Homo Erectus Used a Variety of Stone Tools for Hundreds of Thousands of Years, Study Finds


3/4/20

https://www.newsweek.com/homo-erectus-stone-tools-study-1490491



----------------------------------------------------------------



Ape Skulls Shed Light on the Sex Lives of Our Early Human Ancestors

5/4/17

The skull of Paranthropus aethiopicus. The crest at the top of the skull was thought to be related to diet, but scientists now believe it served sexual selection function too.

https://www.newsweek.com/human-ancestors-sex-lives-social-structure-evolution-594525


----------------------------------------------------------------



What Makes Us Human: Dopamine Injection Boosted Our Brains to Set Us Apart From Chimps and Monkeys

11/24/17


https://www.newsweek.com/human-brain-dopamine-intelligence-chimps-monkeys-721321




----------------------------------------------------------------


Neanderthals Were Doomed to Go Extinct: Our Ancient Relatives 'Drifted' Into Oblivion


10/31/17

https://www.newsweek.com/neanderthal-extinction-doomed-early-human-migration-697686


----------------------------------------------------------------




How We Got Here: Evolutionary Changes in Skull Shape in Humans & Their Ancestors

2012

https://www.jstor.org/stable/10.1525/abt.2012.74.2.8?seq=1


---------------------------------------------


Getting to the Root of Enamel Evolution

May 5, 2014

Connecting genes to hominin teeth shows evidence of natural selection

https://today.duke.edu/2014/05/enamelevolution


---------------------------------------------


On aspects of skull form in African apes and orangutans, with implications for hominoid evolution

 November 1985

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajpa.1330680304


---------------------------------------------


There is a third species of orangutan and somehow nobody noticed

2 November 2017

https://www.newscientist.com/article/2152276-there-is-a-third-species-of-orangutan-and-somehow-nobody-noticed/


---------------------------------------------


Orangutan genome 'evolved slowly'

27 January 2011

https://www.bbc.com/news/science-environment-12286281


---------------------------------------------


Extinct 2-million-year-old giant ape was direct relative of orangutan

16th November, 2019

Meet Gigantopithecus blacki, the three-metre-tall, 600 kg, 2 million-year-old ancestor of the modern-day orangutan.

https://www.sciencefocus.com/nature/extinct-2-million-year-old-giant-ape-was-direct-relative-of-orangutan/


---------------------------------------------


Ancient Ape with 'Human Legs' and 'Orangutan Arms' Moved Like No Other Creature on Earth

November 06, 2019

https://www.livescience.com/danuvius-ape-new-species.html

Now, scientists have unearthed a new fossil great ape with complete limb bones that lived during the Miocene about 11.62 million years ago in what is now Bavaria in Germany.

The paleontologists named the species Danuvius guggenmosi. "Danuvius" is derived from the Celtic-Roman river god Danuvius, and "guggenmosi" honors Sigulf Guggenmos, who discovered the site where the fossil was found.



---------------------------------------------


The legacy of a great scientific hoax

The University of Melbourne’s anatomy museum features fossil models from an entirely fictional early human; a forgery that derailed the study of our evolution for decades

https://pursuit.unimelb.edu.au/articles/the-legacy-of-a-great-scientific-hoax


---------------------------------------------


Ontogenetic study of the skull in modern humans and the common chimpanzees: neotenic hypothesis reconsidered with a tridimensional Procrustes analysis.

2002

https://www.ncbi.nlm.nih.gov/pubmed/11953945



---------------------------------------------



Scientists home in on origin of human, chimpanzee facial differences

A study of species-specific regulation of gene expression in chimps and humans has identified regions important in human facial development and variation.

https://med.stanford.edu/news/all-news/2015/09/scientists-home-in-on-origin-of-human-chimpanzee-facial.html



----------------------------------------------



Homo sapiens, Chimpanzees and the Enigma of Language

31 May 2019

https://www.frontiersin.org/articles/10.3389/fnins.2019.00558/full



--------------------------------------------



The Difference Between Chimpanzee Skulls & Human Skulls

March 13, 2018

https://sciencing.com/difference-chimpanzee-skulls-human-skulls-8311413.html



-------------------------------------------



Humans Evolved Flexible, Lopsided Brains

April 23, 2013

https://www.livescience.com/28986-humans-evolved-asymmetric-brains.html



--------------------------------------------



Morphological distance between australopithecine, human and ape skulls

January 1996

https://link.springer.com/article/10.1007/BF02456987



-------------------------------------------



What Gave Some Primates Bigger Brains? A Fruit-Filled Diet

March 28, 2017

https://www.elsevier.com/connect/why-lucys-baboon-bone-is-great-for-science-and-evolution-theory



--------------------------------------------



How Are Humans Related to Other Primates?: A Guided Inquiry Laboratory for Undergraduate Students

2006

https://www.genetics.org/content/172/3/1379


--------------------------------------------


Riddle of the Bones

https://www.pbs.org/wgbh/evolution/humans/riddle/look.html


--------------------------------------------


 Primate Cranial Diversity

https://www.nature.com/scitable/knowledge/library/primate-cranial-diversity-108207646/














Figure 4: Orbital size and orientation.


Nocturnal primates such as tarsiers (a) and owl monkeys (c) have relatively larger orbital apertures than diurnal species, such as the bamboo lemur (b) and capuchin monkey (d). Small body size and lack of retinal adaptations to low-light vision further contribute to extreme eye hypertrophy in nocturnal haplorhines (a,c). Orbital convergence (purple arrows) is generally greater in haplorhines such as the colobus monkey (f), whose orbits are anteriorly directed, than in strepsirrhines (e), whose orbits are more laterally directed. Frontation, which describes the vertical orientation of the orbital aperture (purple discs) relative to the neurocranium and/or lower face, is also generally greater in haplorhines (h), whose orbits are more vertical than those of strepsirrhines (g). Skull images not to scale.

















Figure 5: Facial kyphosis and browridge development.

The angular orientation of the face relative to the neurobasicranium (kyphosis) is described in terms of klinorhynchy (greater kyphosis) versus airorhynchy (less kyphosis). In more klinorhynch primates (a), the face is rotated ventrally and posteriorly (counterclockwise red arrow) relative to the neurobasicranium (NB, blue); in more airorhynch species (b), the face is rotated dorsally and anteriorly relative to the neurobasicranium (clockwise red arrow). In large-bodied apes and Old World monkeys, klinorhynchy is associated with neuro-orbital disjunction, a spatial separation between the orbit and the anterior neurocranium (a, green arrow), and a relatively longer browridge (yellow arrow) than in more airorhynch taxa (b). In (c) and (d), sagittal CT sections of adult male Gorilla and Pongo crania illustrate variation in facial kyphosis and browridge development. In the relatively klinorhynch gorilla (c), the lower face (palate, red line) is ventrally oriented relative to the cranial base (clival plane, blue line). The orbital apertures are widely separated from the anterior braincase (green arrow), and the browridge (yellow arrow) is prominent. In the relatively airorhynch orangutan (d), the lower face (palate, red line) is dorsally oriented relative to the basicranium (clival plane, blue line). Neuro-orbital disjunction is absent; there is no true browridge; and the nasopharynx (NPh, black arrow) is less restricted than in the gorilla (c). Because of the need to maintain an open airway, the position of the nasopharynx (NPh) between the palate and the cranial base is a potential constraint on facial kyphosis in relatively long-faced species. Cranial images are not to scale.




-------------------------------------------------------



 Gigantopithecus Blacki: Bigfoot-Giganto Theory

June 18, 2019

https://exemplore.com/cryptids/Gigantopithecus-Blacki-The-Real-Bigfoot



----------------------------------------------------------



MONSTER FOUND ‘Original Bigfoot’ was giant ape twice the size of a human that roamed Earth 2 million years ago

15 Nov 2019

https://www.thesun.co.uk/tech/10352675/original-bigfoot-giant-ape-evidence-found/



------------------------------------------------------------




‘Giants’ in the land: an assessment of Gigantopithecus and Meganthropus









Figure 1. In comparison with a human mandible (right), or even that of a gorilla (centre), the dimensions of the biggest of the lower jaws of the giant ape Gigantopithecus (left) is enormous. Note that, although restored in the illustration, the ascending portion of the ape’s jaw was not present in any of the four fossil jaws of Gigantopithecus (after Simons and Ettel).


https://creation.com/giants-in-the-land-an-assessment-of-gigantopithecus-and-meganthropus



----------------------------------------------------------



Gigantopithecus Diet Revealed

Nov 15, 2011

http://www.sci-news.com/paleontology/gigantopithecus-diet-revealed.html



---------------------------------------------------------



Gigantopithecus blacki: a giant ape from the Pleistocene of Asia revisited

20 January 2017

https://onlinelibrary.wiley.com/doi/full/10.1002/ajpa.23150








---------------------------------------------------------



Dated co-occurrence of Homo erectus and Gigantopithecus from Tham Khuyen Cave, Vietnam

April 2, 1996

https://www.pnas.org/content/93/7/3016



----------------------------------------------------------



Ancient enamel sheds light on extinct giant ape

 14 November 2019

https://cosmosmagazine.com/palaeontology/ancient-enamel-sheds-light-on-extinct-giant-ape



----------------------------------------------------------



Assessing Mandibular Shape Variation Within Gigantopithecus Using a Geometric Morphometric Approach

2008

http://www.references.260mb.com/Biometria/Miller2008.pdf?i=1



----------------------------------------------------------



Key to early humans found in giant ape’s tooth


15 November 2019


In 1935, anthropologist Gustav von Koenigswald found a strange set of teeth in a traditional medicine store in Hong Kong.

The specimens were being sold as “dragon teeth” but when he examined them, von Koenigswald was puzzled to find that they looked exactly like the teeth of a great ape — but impossibly huge.

Gigantopithecus blacki was an ancient ape — a “King Kong” — that went extinct around 300,000 years ago. At 10-feet-tall and weighing twice as much as a gorilla, G. blacki would tower over the tallest-ever human by almost half a metre...

https://theday.co.uk/stories/key-to-early-humans-found-in-giant-ape-s-tooth


----------------------------------------------------------



Evolutionary trend in dental size in Gigantopithecus blacki revisited

April 2015

https://www.researchgate.net/publication/275279347_Evolutionary_trend_in_dental_size_in_Gigantopithecus_blacki_revisited



-----------------------------------------------------------



The facial skeleton of the chimpanzee-human last common ancestor

2008


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409098/



-----------------------------------------------------------



Extinct giant ape directly linked to the living orangutan


November 13, 2019

https://www.sciencedaily.com/releases/2019/11/191113153053.htm


By using ancient protein sequencing, researchers have retrieved genetic information from a 1.9 million year old extinct, giant primate that used to live in a subtropical area in southern China. The genetic information allows the researchers to uncover the evolutionary position of Gigantopithecus blacki, a three-meter tall and may be up to 600 kg heavy primate, revealing the orangutan as its closest, living relative.



-----------------------------------------------------------



Why Earth's Largest Ape Went Extinct

January 11, 2016

https://www.livescience.com/53313-biggest-ape-forest-dweller.html



------------------------------------------------------------




Researchers Shake Up Lemur Family Tree

April 26, 2016

https://news.stonybrook.edu/research/researchers-shake-up-lemur-family-tree/




-------------------------------------------------------



Fossils Rewrite the Story of Lemur Origins

https://lemur.duke.edu/fossils-rewrite-the-story-of-lemur-origins/



-------------------------------------------------------



Evidence of early butchery of giant lemurs in Madagascar

2005

https://cpb-us-w2.wpmucdn.com/campuspress.yale.edu/dist/e/421/files/2015/01/Perez-et-al-2012.pdf



-------------------------------------------------------




Why Lemurs Smell Better than You

http://www.bu.edu/articles/2018/primate-sense-of-smell/




-------------------------------------------------------




Do Muscles Constrain Skull Shape Evolution in Strepsirrhines?

2018

https://anatomypubs.onlinelibrary.wiley.com/doi/pdf/10.1002/ar.23712



-----------------------------------------------------------



Why Ida fossil is not the missing link

21 May 2009

https://www.newscientist.com/article/dn17173-why-ida-fossil-is-not-the-missing-link/



-------------------------------------------------------------



Biology 220 -Human Evolution Lab

A comparison of primate skulls
D. Sillman, Penn State New Kensington

http://www.personal.psu.edu/dys100/Evolution.pdf



-------------------------------------------------------------



Development and growth in skulls of three Otariidae species: a comparative morphometric study

November 2018

https://www.cambridge.org/core/journals/journal-of-the-marine-biological-association-of-the-united-kingdom/article/development-and-growth-in-skulls-of-three-otariidae-species-a-comparative-morphometric-study/B1037852BAF6AA7DB047F77ABF7A27FD


-------------------------------------------------------------



Do these skulls prove common ancestry between apes and humans?

6 October 2018

https://creation.com/ape-human-transitional-skull



-------------------------------------------------------------



 A Brief History of Life on Earth: The Full Series


Aug 9, 2017


https://www.youtube.com/watch?v=-Wfu0GR-mE8



------------------------------------------------------------



 How early mammals evolved night vision to avoid predators

June 20, 2016

https://www.sciencedaily.com/releases/2016/06/160620140929.htm


---------------------------------------------------------------



Phototransduction and the Evolution of Photoreceptors

2010

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898276/



---------------------------------------------------------------



Octopus And Squid Evolution Is Officially Weirder Than We Could Have Ever Imagined

17 MARCH 2018


https://www.sciencealert.com/octopus-and-squid-evolution-is-officially-weirder-than-we-could-have-ever-imagined

 


---------------------------------------------------------------


Squid evolved in marine wars more than 100 million years ago

1 March 2017

https://www.newscientist.com/article/2123118-squid-evolved-in-marine-wars-more-than-100-million-years-ago/


-------------------------------------------------------------------------------



Two eyes for two purposes: in situ evidence for asymmetric vision in the cockeyed squids Histioteuthis heteropsis and Stigmatoteuthis dofleini

05 April 2017

https://royalsocietypublishing.org/doi/10.1098/rstb.2016.0069



----------------------------------------------------------------------------------



Human Brains Have Evolved Unique 'Feel-Good' Circuits

November 23, 2017

https://www.npr.org/sections/health-shots/2017/11/23/566034172/human-brains-have-evolved-unique-feel-good-circuits



--------------------------------------------------------------------------------------




Did Humans Really Evolve from Ape-Like Creatures?

May 29, 2018


https://answersingenesis.org/adam-and-eve/did-humans-really-evolve-from-ape-like-creatures/


Christian Assumptions about the Origin of Man

Most Bible-believing Christians in America believe that God created man and all other kinds of animals and plants in essentially their present form (generally represented by the family, not the species, taxonomic classification) by the power of His Word and Spirit. They observe and recognize the ongoing processes of extinction and limited variation within each kind, but point out that this has never been shown to produce fundamentally new kinds of creatures. Thus, they believe God created apes and God created men, but God did not create “ape-men” and apes didn’t change into man (with or without God’s providence). There are, however, a substantial number of professing Christians who believe God used evolution to “create.” But rarely do they specify what actual role God plays in evolution, or even if His existence is necessary for the evolution of the material cosmos.

Those Christians who attempt to accommodate evolution should reflect on the fact that professional evolutionists believe that religion itself is a product of evolution. Out of 14 billion years of purely materialistic cosmic evolution, religion is claimed to have evolved in the imagination of man’s ancestors only a few hundred thousand years ago. As the evolutionist Julian Huxley once put it, “Evolution is the whole of reality, a single process of self-transformation.”8 Theologians and Christian laymen should be aware that evolution is a jealous “god” that will have no other gods before it.

Evolutionist Assumptions about the Origin of Man

The foundational assumption of evolutionism is that evolution is a purely scientific and materialistic (naturalistic) explanation for the origin of everything that is real (i.e., the material universe). Divine intervention and intelligent design are anathema to nearly all evolutionary scientists. Nothing is considered to be above or outside of evolution, including the origin of man and his mental faculties. Even religion is considered to be a product of evolution. For example, an evolutionist from Humboldt University in Berlin observed chimps throwing rocks at trees for no apparent reason and concluded that this was a “worship ritual” telling us something about the evolution of religion. This was widely and enthusiastically reported in the popular media under the banner “Chimps believe in God!”9

Evolutionists assume that amoeba-to-man evolution is an absolute fact, though they concede that the details regarding the actual mechanism of biological evolution and what creature evolved into what are theoretical or even speculative. In the case of human evolution, it is considered an unassailable fact that humans have evolved from nonhuman ancestors. Thus, paleoanthropologists never ask the question, “Did man evolve from ape-like creatures?” Indeed, such a question would likely be career-ending. Paleoanthropologists need only concern themselves with which of the ape-like creatures that have been found in the fossil record are our ancestors. They are certain that at least some of these fossil apes must be our ancestors or else we wouldn’t have any ape-like ancestors, and that’s unthinkable to an evolutionist.

Another primary assumption of evolutionism is that the degree of anatomical, functional, and genetic similarity between two creatures is considered evidence of their degree of evolutionary relatedness. For example, humans are obviously more similar to apes than they are to fish, so our presumed evolutionary relationship to apes is considered to be much closer than it is to fish. But even fish are considered to be our distant relatives, because we both have vertebrae and other similarities common to vertebrates.

But there are countless examples of striking structural and functional similarities between unrelated organisms that make no sense in terms of evolutionary relatedness. For example,

    Opossums and primates have an opposable thumb.
    Australian koalas have fingerprints almost indistinguishable from humans.
    Bats, whales, and shrews have similar sonar-like echolocation.
    Among vertebrates, only mammals and certain salamanders and fish have non-nucleated red blood cells.
    There are many strikingly similar pairs of marsupial and placental mammals, yet evolutionists believe the two separated 160 million years ago.
    A single cell dinoflagellate (protozoan) has been found with a vertebrate-like camera eye consisting essentially of a cornea, lens, and retina derived from subcellular organelles including mitochondria and plastids.

All of these similarities are “explained” by evolutionists with a rescuing hypothesis called “convergent evolution.” Convergent evolution is when two distantly related or unrelated creatures are claimed to have independently evolved by chance the same trait or traits. It would seem that evolutionists consider anything possible, even probable, except intelligent design of biological systems by our Creator.


--------------------------------------------


Retardation and neotony in human evolution

http://www.leeds.ac.uk/chb/lectures/anthl_06.html


---------------------------------------------


 The Comparison of Mean IQ in Muslim and Non-Muslim Countries

March 2010

https://www.researchgate.net/publication/287555828_The_Comparison_of_Mean_IQ_in_Muslim_and_Non-Muslim_Countries


Abstract

The present research found that the Muslim country mean IQ of 81 is half a standard deviation below the mean IQ of non-Muslim nations and is not related to strength of Muslim culture as defined by the percentage of Muslims in the country. The mean IQ of 84 in Arab countries is not associated with per capita income and is incompatible with the intellectual achievements of the golden age of the Muslim Empire. Possible explanations for this decline include hybridization with sub-Saharan Africans, dysgenic decrease in the more educated Muslims employing birth control as suggested by Meisenberg, the Muslim religion not fostering critical thinking, and the intellectual contributions being both exaggerated and made by non-Muslims.




-----------------------------------

      

Low IQ muslim Inbreeding based on the ideology proves islam has the potential of wiping out civilization as we know it


April 24, 2018


https://www.newscats.org/?p=14505

-----------------------------------


Pretending that Intelligence Doesn’t Matter

https://dana.org/article/pretending-that-intelligence-doesnt-matter/


-----------------------------------



UK PM's adviser quits amid backlash over comments on IQ, race


17 Feb 2020


Andrew Sabisky once suggested black people had lower IQs and discussed the benefits of forced contraception.

https://www.aljazeera.com/news/2020/02/uk-pm-adviser-quits-backlash-comments-iq-race-200217212843058.html


------------------------------------



Speak Out: Inbred Muslims

https://www.semissourian.com/forums/speakout/thread/6660



---------------------------------------------


Why Are Modern Humans Relatively Browless?

July 2018

The function of early hominins’ enlarged brow ridges, and their reduction in size in Homo sapiens, have puzzled paleoanthropologists for decades.

https://www.the-scientist.com/notebook/raising-brows-64344


---------------------------------------------



Are Neanderthals Human?

September 19, 2012

Neanderthals present a conundrum well known in biology: What exactly is a species?


https://www.pbs.org/wgbh/nova/article/are-neanderthals-human/


Europeans and Asians carry a small portion of DNA inherited from Neanderthals.

But some researchers challenged this view. They pointed out that for thousands of years, Europe was home to the burly Neanderthals as well as slender humans. Neanderthals didn't give rise to living Europeans, these scientists argued; they were replaced by immigrants expanding out of Africa—perhaps even outcompeted into extinction.

Over the past 15 years, Svante PÀÀbo, a geneticist at the Max Planck Institute of Evolutionary Anthropology, and his colleagues have uncovered an entirely new source of evidence about the nature of Neanderthals: their DNA. Starting with those fossils from the Neander Valley, they extracted bits of genetic material that had survived tens of thousands of years. Eventually, they were able to assemble the fragments into the entire Neanderthal genome.


(Australian Aborigines have a prominent brow ridge, a fact that helped lead Thomas Huxley to argue that Neanderthals were indeed human).


A question of breeding

That's a long time—long enough to reasonably ask if humans and Neanderthals are indeed two separate species. Old species split into new ones when some of their members get isolated from the rest. If a river cuts the range of a species of frog in two, for example, the frogs on one side of the river may only be able to mate with one another. Each population will evolve along its own path. If they are isolated long enough, they will have trouble interbreeding. They may even be unable to interbreed at all.

From these facts of evolution, the biologist Ernst Mayr developed what came to be known as the Biological Species Concept in the 1940s—namely, a species is made up of members of populations that actually or potentially interbreed in nature. Experiments on living animals have shown that barriers to this interbreeding can arise in tens of thousands, or even just thousands, of years.

Once the Neanderthal lineage left Africa 800,000 years ago, did humans and Neanderthals have enough time to become unable to interbreed? PÀÀbo's research provides an answer: no.



---------------------------------------------


 A 150-Year Conundrum: Cranial Robusticity and Its Bearing on the Origin of Aboriginal Australians

2011

https://www.hindawi.com/journals/ijeb/2011/632484/


---------------------------------------------------------------


Do Australian Aboriginal people have low intelligence and sexual control?


https://skeptics.stackexchange.com/questions/35866/do-australian-aboriginal-people-have-low-intelligence-and-sexual-control

 

---------------------------------------------------------------


Meet Australian Aborigines–They Make African Americans Look Like A Model Minority

https://www.unz.com/article/meet-australian-aborigines-they-make-african-americans-look-like-a-model-minority/


---------------------------------------------------------------


Poor Performance by Dark Skin Aboriginals on Q&A

2014

"Aboriginal" heavy episode of Q&A showed a sharp difference between the biracial aboriginals and the full blooded ones. The biracial ones were eloquent and intelligent, the full blooded ones could not speak well and appeared less intelligent.

https://www.youtube.com/watch?v=q7bcVqPqNp0


---------------------------------------------------------------



"Scientist" claiming that the average Australian aborigine is only capable of emptying the rubbish

https://www.thestudentroom.co.uk/showthread.php?t=2596989

He states that the Australian aborigines and sub-saharan bushmen have average IQs of 62 and 60 respectively (an IQ of <70 is usually defined as mentally handicapped), and then he's asked what kind of job a person with an IQ at this level would be capable of he responds with "emptying the rubbish".

Is this just politically charged racism or do his claims actually have some measure of validity?

---------------------------------------------------------------



A quantitative study of Australian aboriginal and Caucasian brains.

1987

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1261675/


---------------------------------------------


Earliest evidence of artificial cranial deformation in Croatia during 5th-6th century

August 21, 2019

Head shape may have distinguished social groups among diverse cultures during migration period


https://www.sciencedaily.com/releases/2019/08/190821142725.htm


------------------------------------------------------


Pointy Skulls Belonged to ‘Foreign’ Brides, Ancient DNA Suggests

Archaeologists have long suspected that modified skulls in German burials belonged to the Huns. Now genetic evidence may confirm it.

https://www.nationalgeographic.com/news/2018/03/barbarian-huns-dna-germany-migration-antiquity-skull/


------------------------------------------------------



Researchers discover genetic mutation behind serious skull disorder


July 01, 2019


https://today.oregonstate.edu/news/researchers-discover-genetic-mutation-behind-serious-skull-disorder



 CORVALLIS, Ore. – A collaboration led by scientists at Oregon State University, the University of Oxford in the United Kingdom and Erasmus University in The Netherlands has identified a new genetic mutation behind the premature fusing of the bony plates that make up the skull.

The findings are a key step toward preventing a serious cranial condition that affects roughly one child in 2,250, and also toward understanding how the protein the gene encodes works in the development and function of other organ systems such as skin, teeth and the immune system.

In the skull, when one or more of the fibrous joints, called skull sutures, between cranial bones close too soon – a condition known as craniosynostosis – the resulting early plate fusion disrupts proper growth of the skull and brain.

Pressure inside the cranium can lead to a variety of medical problems including impaired vision, respiration and mental function, as well as abnormal head shape. Males are affected at slightly higher rates, and most cases are termed “sporadic” – meaning they occur by chance.

“As an individual grows, sutures are supposed to close gradually, with complete fusion taking place in the third decade of life,” said Oregon State researcher Mark Leid. “Proper suture formation, maintenance and ossification require an exquisitely choreographed balance – stem cells and their progeny need to proliferate and differentiate at just the right time.”

Leid, professor and interim dean of the OSU College of Pharmacy, and scientists Stephen Twigg of Oxford and Irene Mathijssen of Erasmus University in Rotterdam performed whole-genome sequencing on a male craniosynostosis patient and found a mutation in a gene known as BCL11B.

Neither of the patient’s parents had symptoms of craniosynostosis, a family history of the condition, or carried the mutation, which generated a single amino acid change in the BCL11B protein.

The international research group proved that the human patient’s mutation was causative for craniosynostosis by utilizing a mouse model harboring the same mutation. Like the human patient, the genetically modified mouse exhibited craniosynostosis at birth.

“Our data demonstrate that the identified amino acid substitution caused craniosynostosis in the patient we studied,” Leid said. “The mouse model that we created should be useful in dissecting the mechanisms behind the role of the BCL11B protein in keeping sutures open, as well as the role of the protein in the development and function of other organ systems.”


------------------------------------------------------

{The premature fusing of the bony plates that make up the skull seem to also be a problem in mice, including Orientals and Negroes. This is the same reason why Orientals and blacks have eye and nasal problems, and this is also why we consider Orientals and blacks to have  brachycephalic and
often deformed looking faces. This is why we need strict population control and to limit the numbers of Negros, Orientals and Indians}.

------------------------------------------------------



Genetically-modified bone mesenchymal stem cells with TGF-ÎČ3 improve wound healing and reduce scar tissue formation in a rabbit model.

2018

https://www.ncbi.nlm.nih.gov/pubmed/29453974


---------------------------------------------------------


Nanobiomechanics of repair bone regenerated by genetically modified mesenchymal stem cells.

2008

https://www.ncbi.nlm.nih.gov/pubmed/18620480


---------------------------------------------------------


Treatment of Bone Defects by Transplantation of Genetically Modified Mesenchymal Stem Cell Spheroids

June 2018


https://www.sciencedirect.com/science/article/pii/S2329050118300445


---------------------------------------------------------


Genetically Modified Human Bone Marrow Derived Mesenchymal Stem Cells for Improving the Outcome of Human Islet Transplantation

October 29, 2013

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077591


---------------------------------------------------------



Genetically modified bone marrow continuously supplies anti-inflammatory cells and suppresses renal injury in mouse Goodpasture syndrome

2001

https://ashpublications.org/blood/article/98/1/57/88911/Genetically-modified-bone-marrow-continuously


---------------------------------------------------------


Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine model

May 2007

https://online.boneandjoint.org.uk/doi/full/10.1302/0301-620X.89B5.18343


---------------------------------------------------------



Implant Composed of Demineralized Bone and Mesenchymal Stem Cells Genetically Modified with AdBMP2/AdBMP7 for the Regeneration of Bone Fractures in Ovis aries

2016

https://www.hindawi.com/journals/sci/2016/7403890/


---------------------------------------------------------



Determination of the Chondrogenic Differentiation Processes in Human Bone Marrow-Derived Mesenchymal Stem Cells Genetically Modified to Overexpress Transforming Growth Factor-ÎČ via Recombinant Adeno-Associated Viral Vectors

21 Oct 2014

https://www.liebertpub.com/doi/abs/10.1089/hum.2014.091



--------------------------------------------------------


Erythropoietin Delivery by Genetically Engineered Bone Marrow Stromal Cells for Correction of Anemia in Mice with Chronic Renal Failure

June 2006

https://jasn.asnjournals.org/content/17/6/1576


-----------------------------------------------------



Articular cartilage repair by genetically modified bone marrow aspirate in sheep

11 March 2010

https://www.nature.com/articles/gt201016


---------------------------------------------------------


Genetic engineering promises improved bone marrow transplants

18 February 2019

https://cosmosmagazine.com/biology/genetic-engineering-promises-improved-bone-marrow-transplants



---------------------------------------------------------


Intrathecal administration of human bone marrow mesenchymal stem cells genetically modified with human proenkephalin gene decrease nociceptive pain in neuropathic rats

April 5, 2017

https://journals.sagepub.com/doi/10.1177/1744806917701445


---------------------------------------------------------



Genetically Modified Animal Models as Tools for Studying Bone and Mineral Metabolism

2004

https://asbmr.onlinelibrary.wiley.com/doi/pdf/10.1359/JBMR.040206



---------------------------------------------------------


Breakthrough Mouse Research Shows Stem Cells Can Be Genetically Edited Inside The Body

6 JUNE 2019

https://www.sciencealert.com/breakthrough-research-shows-stem-cells-can-be-genetically-edited-inside-the-body


---------------------------------------------------------


Genetically modified mesenchymal stromal cells in cancer therapy

November 2016

https://www.celltherapyjournal.org/article/S1465-3249(16)30512-6/fulltext


---------------------------------------------------------




Genetically Modified Mesenchymal Stem Cells Induce Mechanically Stable Posterior Spine Fusion

 2010

http://www.kumc.edu/Documents/msctc/Sheyn%20D,%20Tissue%20Eng%20Part%20A.%202010%20.pdf



---------------------------------------------------------



Blue Dye in M&Ms Helps Spinal Cord Injuries?

2009

Compound Similar to Food Dye May Help People With Spinal Injuries Regain Movement

https://www.webmd.com/brain/news/20090729/blue-dye-mms-helps-spinal-cord-injuries



---------------------------------------------------------



Sky-blue dye could help repair damaged heart tissue

January 12, 2020

The small molecule reduces damaging inflammation and improves heart function in mouse models of heart attack, say Israeli scientists.


https://www.israel21c.org/sky-blue-dye-could-help-repair-damaged-heart-tissue/


---------------------------------------------------------


 Genetically modified apple that won't turn brown coming soon


Oct 10, 2017

https://www.nydailynews.com/life-style/genetically-modified-apple-won-turn-brown-coming-article-1.3553922


---------------------------------------------------------



This Genetically Modified Lettuce May Help In Healing Bone Fracture

February 26, 2020

A new study has discovered genetically modified lettuce plants which could stimulate the growth of bone-building cells and promote bone regeneration

https://food.ndtv.com/news/this-genetically-modified-lettuce-may-help-in-healing-bone-fracture-2186041


----------------------------------------------------------



Genetically Engineered Purple Tomato could fight cancer

October 27, 2008

https://www.discovermagazine.com/health/genetically-engineered-purple-tomato-could-fight-cancer



----------------------------------------------------------



The dominant developmental mutants of tomato, Mouse-ear and Curl, are associated with distinct modes of abnormal transcriptional regulation of a Knotted gene.


1997

https://www.ncbi.nlm.nih.gov/pubmed/9437860



----------------------------------------------------------



Scientist famous for human ear on mouse accused of cheating

Aug 26, 2011

https://www.irishtimes.com/news/scientist-famous-for-human-ear-on-mouse-accused-of-cheating-1.606723


----------------------------------------------------------



The Monsanto GMO Story: Adding a Fish Gene Into Tomatoes

 April/May 2000

https://www.motherearthnews.com/real-food/adding-a-fish-gene-into-tomatoes-zmaz00amzgoe



----------------------------------------------------------



Genetically-modified purple tomatoes heading for shops

24 January 2014


https://www.bbc.com/news/science-environment-25885756


----------------------------------------------------------



Genetically engineering tomatoes to fight bone growth defects in animals

Mar 29, 2016

https://indiabioscience.org/news/2016/genetically-engineering-tomatoes-to-fight-bone-growth-defects-in-animals


----------------------------------------------------------


The Genetically Modified Foods That Affect Bone Density


https://saveourbones.com/the-gmo-foods-that-affect-bone-density/


----------------------------------------------------------



 The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs

 Jun 11, 2019

https://elifesciences.org/articles/42866/figures



----------------------------------------------------------



Plasmid-based genetic modification of human bone marrow-derived stromal cells: analysis of cell survival and transgene expression after transplantation in rat spinal cord


14 December 2007

https://bmcbiotechnol.biomedcentral.com/articles/10.1186/1472-6750-7-90


---------------------------------------------------------



In A 1st, Doctors In U.S. Use CRISPR Tool To Treat Patient With Genetic Disorder

July 29, 2019


For the first time, doctors in the U.S. have used the powerful gene-editing technique CRISPR to try to treat a patient with a genetic disorder.

"It is just amazing how far things have come," says Victoria Gray, 34, of Forest, Miss. "It is wonderful," she told NPR in an exclusive interview after undergoing the landmark treatment for sickle cell disease.

Gray is the first patient ever to be publicly identified as being involved in a study testing the use of CRISPR for a genetic disease.


https://www.npr.org/sections/health-shots/2019/07/29/744826505/sickle-cell-patient-reveals-why-she-is-volunteering-for-landmark-gene-editing-st



----------------------------------------------------------


QUANTITATIVE ANALYSIS OF MINERAL/MATRIX TO EVALUATE GENETICALLY ALTERED BONE WITH INFRARED SPECTROSCOPY AND X-RAY SPECTRAL IMAGING


Abstract

This thesis focuses on the characterization of bone with the help of Fourier Transform Infrared Spectroscopy and Energy Dispersive Spectroscopy. Such analysis of the physics and chemistry of biomaterials is vital to resolve problems in life science of bone-related diseases and disorders. Material characterization can help in the understanding of disease mechanisms and lead to useful drugs and other treatments. In this thesis, I have used bone materials produced by groundbreaking research at UT Southwestern Research Center and Texas Scottish Rite Children's Hospital to establish that idiopathic clubfoot (Talipes equinovarus) is associated with the Follistatin 5 gene. We studied healthy wild-type laboratory rats in comparison with genetically modified rats, called knock-out type, in which function of the Follistatin 5 gene was controlled with genetic engineering. We were able to identify significant differences in mineral and matrix composition of bone despite considerable variability in the samples. For mid-diaphysis of bone, matrix content was reduced in the knockout compared to the wild-type, leading to the increased mineral to matrix ratio in the knockout.

https://rc.library.uta.edu/uta-ir/handle/10106/27477



-----------------------------------------------------------



Scientists say genetically modified babies will have shorter lives

June 4th, 2019

https://bgr.com/2019/06/04/crispr-baby-genetic-modification-life-expectancy/

In late 2018 a Chinese scientist name He Jiankui performed work that has gained him not only the criticism of his peers but also backlash from his home country’s government. He took the extraordinary step of performing genetic modification on human embryos with the intention of having them carried to term. A pair of newborns resulted from the work, marking the start of a potentially dangerous new era of genetic experimentation.

The decision to genetically modify the babies has been roundly decried by others in the genetics field, and a new paper published in Nature Medicine suggests that the modifications He made to the two children may ultimately doom them to early deaths.



---------------------------------------------------------



Will we ever have genetically modified astronauts?

24th November 2017


https://www.bbc.com/future/article/20171123-will-we-ever-have-genetically-modified-astronauts



---------------------------------------------------------



How scientists are engineering silk to save our bodies

May 4, 2018

It’s strong, stretchy, and compatible with the human body

https://www.theverge.com/2018/5/4/17318362/silk-health-medicine-wounds-genetic-engineering-strength


---------------------------------------------------------



Genetically‑modified stem cells in treatment of human diseases: Tissue kallikrein (KLK1)‑based targeted therapy (Review)

January 3, 2018

https://www.spandidos-publications.com/10.3892/ijmm.2018.3361



---------------------------------------------------------



Read a Harvard geneticist's plan for redesigning humans

21 July, 2019

Professor George Church creates a gene "wishlist" that can lead to superhuman abilities.

https://bigthink.com/surprising-science/harvard-geneticist-plan-for-redesigning-humans



---------------------------------------------------------



3D-Printed Heart Created by Israeli Researchers in World First: 'This Heart Is Made From Human Cells'

4/17/19

https://www.newsweek.com/3d-printed-heart-human-tissue-world-first-1398925



-----------------------------------------------------



High-level expression of porcine factor VIII from genetically modified bone marrow–derived stem cells

May 15, 2006

https://ashpublications.org/blood/article/107/10/3859/109801/High-level-expression-of-porcine-factor-VIII-from



-----------------------------------------------------



Doctors Try Genetically Modified Poliovirus As Experimental Brain Cancer Treatment

June 26, 2018


https://www.npr.org/sections/health-shots/2018/06/26/622610333/doctors-try-genetically-modified-poliovirus-as-experimental-brain-cancer-treatme



-----------------------------------------------------



Genetic Modification of Stem Cells in Diabetes and Obesity

https://www.intechopen.com/books/genetic-engineering-an-insight-into-the-strategies-and-applications/genetic-modification-of-stem-cells-in-diabetes-and-obesity



------------------------------------------------------



A Novel Genetically Engineered Human Osteoblasts for the in Vitro Study of Biomaterials

2008

https://www.oulu.fi/spareparts/ebook_topics_in_t_e_vol4/abstracts/tognon.pdf



------------------------------------------------------



Genetically Modified T Cells Might Help Fight HIV

January 2, 2018

Preliminary work in monkeys suggests stem cells can be engineered to help combat the virus


https://www.scientificamerican.com/article/genetically-modified-t-cells-might-help-fight-hiv/



-----------------------------------------------------



2nd person cured of HIV thanks to stem cell transplant


https://www.medicalnewstoday.com/articles/2nd-person-cured-of-hiv-thanks-to-stem-cell-transplant



-----------------------------------------------------



More about the Viking hypothesis of origin of the delta32 mutation in the CCR5 gene conferring resistance to HIV-1 infection.


2003

https://www.ncbi.nlm.nih.gov/pubmed/14636691


-----------------------------------------------------


Biologists discover why 10% of Europeans are safe from HIV infection


10-Mar-2005


https://www.eurekalert.org/pub_releases/2005-03/uol-bdw031005.php


------------------------------------------------------


The Genetic Mutation Behind the Only Apparent Cure for HIV


March 14, 2019

https://www.thebodypro.com/article/genetic-mutation-behind-hiv-cure


-----------------------------------------------------


 Why Germany's Coronavirus Death Rate Is Far Lower Than In Other Countries

March 25, 2020

https://www.npr.org/2020/03/25/820595489/why-germanys-coronavirus-death-rate-is-far-lower-than-in-other-countries?utm_source=pocket-newtab


---------------------


 Coronavirus: Iceland’s mass testing finds half of carriers show no symptoms

https://english.alarabiya.net/en/features/2020/03/25/Coronavirus-Iceland-s-mass-testing-finds-half-of-carriers-show-no-symptoms


-------------------


 Finland's Fascinating Genes

 April. 2005

The people in this land of lakes and forests are so alike that scientists can filter out the genes that contribute to heart disease, diabetes, and asthma

 http://discovermagazine.com/2005/apr/29-finlands-fascinating-genes


-------------------


{Notice how many white Nordic people in Iceland are immune from the virus, while the Chinese continue to have a higher death rate percentage over Iceland.

America is a white nation. This is what happens when we go from being a first world white nation, to allowing a bunch of 3rd world degenerates and the cursed races such as Blacks, illegal Mexicans, Chinese and degenerates into a first world nation.

America needs to go back to being a white nation in order to stop the degeneration of America.

We demand population control and Race control, we need to round up all the Chinese, Mexicans and blacks, then we must deport these groups back to Africa and Asia}.


------------------------------



Cancer tumors gain drug resistance by eating dead cells

Researchers have identified a mechanism by which tumors become resistant to cancer drugs.

https://www.medicalnewstoday.com/articles/cancer-tumors-gain-drug-resistance-by-eating-dead-cells



---------------------------------------------



Jaws to ears in the ancestors of mammals

https://evolution.berkeley.edu/evolibrary/article/evograms_05

All the animals you see on this evogram are synapsids, the group that gave rise to the mammals. Sometimes synapsids are called "mammal-like reptiles;" however, that is misleading because synapsids are not reptiles. Synapsids and reptiles are two distinct groups of amniotes, animals that produce young that are enveloped with a membrane called an amnion that prevents desiccation. All reptiles (including birds) have eggs with amniotic membranes (which some lay and others retain inside their bodies until hatching). And of course all mammals (the clade of synapsids still alive today) reproduce using an amnion, and those that lay eggs (e.g., the platypus and echidna) produce amniotic eggs.



-----------------------------------------------


Biomechanical Consequences of Rapid Evolution in the Polar Bear Lineage

2010

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974639/


---------------------------------------------------



VARIATION IN SKULL MORPHOLOGY OF BROWN BEARS (URSUS ARCTOS) FROM CAUCASUS

https://academic.oup.com/jmammal/article/79/1/118/841857


----------------------------------------------------


Diet and Morphology of Extant and Recently Extinct Northern Bears


https://www.jstor.org/stable/3873160?seq=1


----------------------------------------------------


From brown to white – evolution of the polar bear

2014.05.09

https://arctic.au.dk/news-and-events/news/show/artikel/from-brown-to-white-evolution-of-the-polar-bear/


----------------------------------------------------


Evolutionary history and palaeoecology of brown bear in North-East Siberia re-examined using ancient DNA and stable isotopes from skeletal remains

14 March 2019

https://www.nature.com/articles/s41598-019-40168-7


----------------------------------------------------




Extinct vegetarian cave bear diet mystery unravelled

July 28, 2018

Summary:

    Until now, very little is known about the dietary evolution of the cave bear and how it became a vegetarian, as the fossils of the direct ancestor, the Deninger's bear (Ursus deningeri), are extremely scarce.

https://www.sciencedaily.com/releases/2018/07/180728083510.htm


----------------------------------------------------


Ancient bear with bad teeth offers insight into modern bear ecology

December 20, 2017

Researchers say cavities in fossilized bear teeth suggest that even early in their evolution, bears geared up for winter by eating sugary berries

https://www.canadiangeographic.ca/article/ancient-bear-bad-teeth-offers-insight-modern-bear-ecology



-----------------------------------------------------



Mandible size and shape in extant Ursidae (Carnivora, Mammalia): A tool for taxonomy and ecogeography

22 June 2017

https://onlinelibrary.wiley.com/doi/full/10.1111/jzs.12171



---------------------------------------------------



Allometric Growth Pattern of Skull on Brown Bear (Ursus arctos Linnaeus, 1758) of the Alborz Mountain

March 2014

https://www.researchgate.net/publication/272478184_Allometric_Growth_Pattern_of_Skull_on_Brown_Bear_Ursus_arctos_Linnaeus_1758_of_the_Alborz_Mountain



----------------------------------------------------


How Grizzlies Evolved into Polar Bears

June 10, 2008

https://www.pbs.org/wnet/nature/arctic-bears-how-grizzlies-evolved-into-polar-bears/777/



----------------------------------------------------



These ancient giant bears evolved separately at the same time

21 April 2016

Short-faced bears, taller than a person when on all  fours, roamed North and South America millions of years ago. A new study suggests they're not related – populations on each continent grew massive independently. Amy Middleton reports.

https://cosmosmagazine.com/biology/these-ancient-giant-bears-evolved-same-time


---------------------------------------------------


Skull Science

https://www.dec.ny.gov/docs/wildlife_pdf/skullscience.pdf


----------------------------------------------------


Skulls of Alaskan Mammals

https://www.pugetsound.edu/files/resources/10169_Alaskan%20skulls%20teacher%20guide.pdf



----------------------------------------------



 The first ancestors of giant pandas probably lived in Europe

2017

https://www.newscientist.com/article/2151717-the-first-ancestors-of-giant-pandas-probably-lived-in-europe/


----------------------------------------------



 A Tale of Two Pandas Case Study

Background

For over a century, scientists debated whether the giant panda was more closely related to bears or the red panda, an animal that is more closely related to the raccoon family. This documents shows multiple pieces of evidence that have been collected over the years—evidence from anatomy, behavior, DNA, and fossils.

https://teach.genetics.utah.edu/content/evolution/ancestry/pdfs/panda-case-study.pdf


------------------------------------------



The first skull of the earliest giant panda

2007

https://www.pnas.org/content/104/26/10932


------------------------------------------


Extinct Giant Panda Lineage Discovered Thanks to DNA From 22,000-Year-Old Skull

2018

https://gizmodo.com/extinct-giant-panda-lineage-discovered-thanks-to-dna-fr-1826874048


------------------------------------------


Cranial shape transformation in the evolution of the giant panda (Ailuropoda melanoleuca).

2010

https://www.ncbi.nlm.nih.gov/pubmed/21132275


------------------------------------------


Bears and Bamboo: The fossil record of giant pandas

01.31.11

https://www.wired.com/2011/01/bears-and-bamboo-the-fossil-record-of-giant-pandas/

------------------------------------------


Raccoon Dog, Nyctereutes procyonoides, Populations in the Area of Origin and in Colonised Regions — The Epigenetic Variability of an Immigrant

February 2009 


https://academic.oup.com/cz/article-pdf/57/5/584/32967619/czoolo57-0584.pdf


--------------------------------------------


EVOLUTION OF CRANIAL CAVITIES IN GIANT PANDAS (AILUROPODA, CARNIVORA, MAMMALIA)

2011

https://www.researchgate.net/publication/271770780_EVOLUTION_OF_CRANIAL_CAVITIES_IN_GIANT_PANDAS_AILUROPODA_CARNIVORA_MAMMALIA



------------------------------------------


Giant Kangaroos Had A Crushing Bite More Akin To A Giant Panda Than A Modern Roo

2019

https://www.iflscience.com/plants-and-animals/giant-kangaroos-had-a-crushing-bite-more-akin-to-a-giant-panda-than-a-modern-roo/



------------------------------------------



Modern panda's extinct pygmy ancestor

2007

https://www.abc.net.au/science/articles/2007/06/19/1955296.htm

The giant panda's earliest known ancestor was a "pygmy-sized" bear that lived about two million years ago in the lowland tropical forests of south China, a new study has found.

This week's Proceedings of the National Academy of Sciences reports on a complete skull of a panda about half the size of the famous current-day bamboo-munching bear.

The skull is about 60% of the size of a modern giant panda's and it has similar anatomical features, suggesting a similar lifestyle, say the researchers who made the discovery.

The extinct bear, named, Ailuropoda microta is the earliest known member of the panda lineage, says team member Professor Russell Ciochon, a University of Iowa palaeoanthropologist.


------------------------------------------


Life in the trees, not bamboo, shaped the panda’s “thumb”

https://www.nationalgeographic.com/science/phenomena/2010/04/13/life-in-the-trees-not-bamboo-shaped-the-pandas-thumb/


-----------------------------------------


How pandas use their heads as a kind of extra limb for climbing

January 28, 2020

https://www.sciencenews.org/article/how-pandas-use-their-heads-extra-limb-climbing


------------------------------------------


This Ancient Panda Skull Belongs to a Previously Unknown Lineage

2018

The fossilized skull represents a panda line that split from today’s fluffy creatures 183,000 years ago


https://www.smithsonianmag.com/smart-news/ancient-panda-skull-belongs-previously-unknown-lineage-180969402/


------------------------------------------


Are the Pandas Successful Specialists or Evolutionary Failures?

1994

https://www.jstor.org/stable/1312297?seq=1



---------------------------------------------




{Since blacks and Mexicans have ghost DNA, that makes them a Cryptic Species or a Subspecies.

We should get rid of 90% of the blacks, Mexicans, Arabs, Indians and Orientals.

We should concentrate on promoting whites for the next future race of humans.

We should phase out many of these brown Denisovan Subspecies such as Indians, Blacks, Mexicans, and we must concentrate on promoting white humans as the future human race.

White humanity could even evolve to something even grander in the future. We need to eliminate many of these Mexicans out of the picture so that future humanity can flourish. Either that or we regulate whites as a 95% majority race, and regulate only 5% of blacks, Hispanics and Asians, just as we see in many movies.

There is a reason why some of the best movies have white people, and why adding too many of these black looking Homo heidelbergensis subspecies does ruin a good movie.


It was a mistake letting many of these blacks and South American Indians overpopulate and ruin the ecosystem. Then now some Chinese and East Indian subspecies have nuclear weapons. We should have eliminated many of these nuisance races during World War II.

It is too bad that the higher IQ white Europeans had to die in World War 1 and World War II. The Allies would have been better off attacking Africa or Mexico instead of attacking other white nations.


It just seems right when humanity tries to flourish that something gets in the way and ruins it.

Such as we had the Rise of Rome, which was a white Empire. Look at how savage Barbarians came over and attacked Romans. The Barbarians and the Romans should have invaded the Middle East and killed Arabs instead, or go and kill black Africans.
You see this is what Rome did, is they conquered Egypt and invaded the Northern Parts of Africa.

We had Greece and Sparta fight each other, while fighting Persians. White Europe should have
united as a giant army to get rid of many of the blacks in Africa and the brown sand people in the Middle East.

Look at how Italy, Germany and Spain joined forces in World War II in order to get the degenerates out of Europe, and they were defeated.
Now look at how Europe has a bunch of browned up degenerate gypsies running around, and the Germans wanted them gone. Now we have more low IQ black degenerates in Europe.

We see how close England got to trying to conquer South Africa, India and many other parts of the world, but instead England had to waste resoures to fight and kill white Americans and white French instead. This is the biggest mistake America, France and England ever made, and that was to kill different white nations, and never finishing the objective of eliminating these Black and brown savages like the white race did in Australia.

We should get rid of many of these black degenerates in South Africa and have strict population control on the numbers of blacks in the world, including limiting the numbers of blacks in Africa and in the rainforests}.



---------------------------------------------------------------------------------



Is South Africa bottom of the class in maths and science? WEF ranking is meaningless

Published: 3 September 2014


https://africacheck.org/reports/is-sa-bottom-of-the-class-in-maths-and-science-why-ranking-is-meaningless/


A report published by the World Economic Forum (WEF) has ranked the quality of South Africa's maths and science education last out of 148 countries. But is the ranking an accurate reflection of the state of schooling in the country?

Major problems do exist

Of course this does not mean that all is well in South Africa. The performance of South Africa’s education system has been subject to severe criticism in recent years.

A 2012 study published by the University of Stellenbosch found that while 71% of children in grade six were functionally literate, only 58.6% could be considered functionally numerate.

The study noted that “at least a quarter of children are enrolled but have learnt so little in six years of formal full-time schooling that they have not even mastered functional literacy or numeracy”.

The basic education department’s own academic assessments revealed last year that just three percent of school pupils in grade nine had achieved more than 50% in mathematics.



--------------------------------------------------------------------------------




Black Youngsta Mumble GIF




https://tenor.com/view/blac-youngsta-mumble-mumbling-trippy-tripping-gif-12080396



-------------------------------------------------------------------------------




{Look at how foolish the wars between England and France were, when they simply should have joined their forces and invaded Africa.

America did a good job of eliminating many of these Indians.
The problem is that America, France and England all killed each other, when they should have joined forces to eliminate the savage low IQ Indians in the Americas. Now we have a bunch of low IQ South American Indians and blacks that are burning down the rainforests, and blacks must be
stopped from destroying the rainforests.

If anything the British Empire were doing the right thing by elimating many of these black savages, while keeping the numbers of these savages down.
It is too bad America and England didn't eliminate more of these Denisovan subspecies of Indians and 3rd world degenerates.



The reason why Germany allied with Japan is that Germany was the highest IQ white European country almost and Japan was the higher IQ Oriental country. If anything Japan could have eliminated many of the overpopulated Filipino people that have lower IQ. The problem is that Japan was getting too much of a threat and bombed Pearl Harbor, and America as a white nation was forced into war with an Oriental nation. I still think that Germany and America should have been allied in World War II and went after the African savages, Muslims and the Communists in China. Japan could have even helped invade China. Then we would have the higher IQ white populations eliminate the lower IQ Africans and Muslims instead of killing off good white DNA. You could keep a smaller portion of the higher IQ Orientals from Japan to help invade China, India, the Philippines and other areas of Asia.
We could have eliminated many of the Chinese, East Indians and Pakistani people, and not give these degenerates the luxury of copying nuclear weapons. Now we have some degenerative Denisovan subspecies with nuclear weapons.

It is still not too late, America and England now have even more technology to eliminate many of these savages once and for all.
We should continue both what England, France, Germany and America wanted, and that is a majority white country.

We should have all whites and all white nations ally to round up all blacks, Mexicans, Arabs and Sterilize 90% of these brown skinned people that are part Denisovan. Sterilize anyone that has an IQ of under 100.


 We hear all this guilt about aparthid in South Africa, when society was better off just eliminating many of these blacks that are now overpopulated and invading Europe. We should work together to eliminate 90% of the blacks, so the blacks stop burning down the rainforests, poaching animals and depleting resources.


Martin Luther King was an Antifa Communist degenerate, and the person who shot Martin Luther King was the real hero.

Do not honor Martin Luther King or Nelson Mandella. We should not have any streets or statues with these Homo heidelbergensis Ghost population subspecies trying to complain how they should overpopulate, deplete resources, then ruin first world nations and the rainforest.

Look at how public schools brainwash kids into thinking Martin Luther King or Nelson Mandella had good movements, when they actually were degenerates that degraded first world society, then further regressed the entire world into a 3rd world nation. This is why we have a bunch of low IQ black gangsters spawning up around the world that have become a nuisance and are now overpopulated.

We should have shipped all the blacks back to Africa and not let blacks degrade America and Europe, this is why we have laws in place to not allow low IQ 3rd world degenerates into a high IQ first world nation. It is still not too late to eliminate many of these savage third world blacks and replace them with a higher IQ population.

Blacks are a subspecies, you should have not let their numbers get to over a billion, this is why much of Africa and South America is now ruined, it is because of the blacks.

Then we see how blacks and 3rd world people illegally immigrate to Europe and America, then we see a pattern of illegals immigrating and stacking too many illegals that take water out of the river systems. This is why North Africa is turning into a desert, why Europe is also drying out,  and why the South West in America along the Mexican border is also drying out.


It was many of these no good blacks, 3rd world degenerates, Communists, Antifa members and overpopulated people to blame for the destruction of the planet and allowing illegals to stack. How is the government or Polution Science 101 supposed to know about the exact amount of people there are in an area. Instead you try to fight so hard to bring more degenerates to dry up the groundwater resources, many of these degenerates care more about stacking illegal Mexicans and illegal blacks into first world nations to overthrow white areas such as Europe and America.
These people could care less about all the resources being used up, and even try to fight the press and call the press racist for not wanting unlawful immigrants from ruining the environment. Look at how bad Mexicans and Blacks trash up and ruin their own countries, and this
is why we are now calling for the elimination of over 90% of the Blacks, Hispanics, Mexicans, Arabs, Indians and Orientals. Please eliminate them and do not let humanity get over 8 billion people.


Look at how much the black people throw away trash in the jungles and pollute in Africa, it is not worth keeping these degenerates around while they throw all their trash out into the forests, burn down the rainforests, illegally dump, including hunting down endangered animals and plants just
to make a profit. It is not worth keeping this many blacks, Mexican, Arabs, Indians and Orientals around, many of these races are overpopulated and have become a nuisance to the rest of the planet. Most of these races were just some Denisovan subspecies, and why the 3rd world degenerates have lower IQ than high IQ whites in Europe.

We know that the Chinese cheat on their IQ test, and that many Orientals are better at copying the car, and that white people actually invented the car. The Chinese are better at counterfeiting white inventions, while whites such as Tesla and Da Vinci were better at inventing inventions.

Orientals are a pretty smart race, and we see that all races have their smart races.

Here is the problem we have, we still cannot replicate some of the technology of the Ancient Egyptians.

Some say that the Ancient Egyptians and the people from Atlantis were more advanced than we are today.

It is debated if our newer technology today is more advanced, or that the people that created ancient Egypt could have been Freemasons or Aliens even.

If you have ever seen the movie Forbidden Planet, where there were actually ancient races of people more advanced than modern humans.



 ---------------------------------------------------------------------


Pleiadians

https://rationalwiki.org/wiki/Pleiadians



--------------------------------------------------------------------


Nordic aliens


https://en.wikipedia.org/wiki/Nordic_aliens



-------------------------------------------------------------------


Top 10 Proof Of Pleiadian Aliens On Earth


https://proofofalien.com/top-10-proof-of-pleiadian-aliens-on-earth/


-----------------------------------------------------------------



{Jews think they are aliens and the Central Americans call themselves the Star people.

Many black Africans believed that a black race of primitive humans lived on the planet Earth, and that Aliens created white people, and that if you are white, that you have more of the Alien DNA in you, and if you are black it means that you are more of an original primitive being on Earth.


Some people try to mention if the Pleiadians are white, or they have a race of white aliens and brown skinned Aliens.


Many would like to believe that humans are not related to Neanderthals or any of these inferior species that we have mentioned. Many would like to think that they were created by a creator, and that we were actually designed as a special type of being that is different from any type of animal you see here on Earth.

We see how the human experience and technology is different from any other animal we see on Earth. Some even think that humans were on other planets, and that humans are just here as a colony to mine for resources}.



-------------------------------------------------------------



Series of Web Pages Convinced Asians are Aliens from Outer Space

November 8, 2010

https://www.8asians.com/2010/11/08/series-of-web-pages-convinced-asians-are-aliens-from-outer-space/



-------------------------------------------------------------



Space aliens are breeding with humans, university instructor says. Scientists say otherwise.

May 25, 2019

https://www.nbcnews.com/mach/science/space-aliens-are-breeding-humans-university-instructor-says-scientists-say-ncna1008971




-------------------------------------------------------------



{Do you think that the humans alive today are degenerates compared to ancient humans, or are humans the most evolved Hominin so far?

Some theories even try to claim that since the Pyramids go back very far in time, that maybe Neanderthals were the race that created the Pyramids, and why we see some elongated heads in the statues of Ancient Egypt. At first I really didn't want to entertain that theory, and that I would see the Neanderthals as a lesser intelligent race than a human. Some say that Neanderthals had a bigger head than humans. I believe that white humans made the Pyramids.

We do hear of a superspecies of giant Aryan humans that used to exist.

Even some religions in Asia believe that the whiter and more fair skinned Orientals are more pure human than the brown skin Orientals that have more subspecies DNA.

Sure all races have been overpopulated, I can't name a race of people that is underpopulated right now. Even Europe is way overpopulated right now.


Look at how it is the savage black Africans that continue to hunt and poach all the species out of the rainforests. Some blacks are no better than a Homo heidelbergensis, and that we let some subspecies ruin the rainforest.

If the British Empire killed off many of these blacks in time, we could have many species of extinct animals and plants that would still be alive in Africa. The same goes for South America with blacks and Indians making endangered plants and animals go extinct.
I think it would have been better if England, France and America eliminated many of these African and South American savages over 150 years ago. We should have had conservation efforts in place of letting these 3rd world degenerates ruin the heart of the Amazon, and threaten the very existence of the Earth.


If I were in charge I would regulate each race, just like a Silverback Gorilla.

For instance, would we want to regulate the population of a Homo heidelbergensis.

Now that people can genetically modify and are doing experiments to create dinosaurs, what if they were able to bring back extinct species of Hominins. I would say that we would want to regulate the amount of genetically modified Hominins so that they would not overpopulate. We see movies such as Planet of the Apes, and how it would be bad to try and release a black Homo heidelbergensis into the wild.

What if we did regulate the races of blacks, Mexicans, Arabs and Orientals just like an animal, I would say we should.

We hear people in the media complaining about how the United Nations wants to classify people as animals, at first I was concerned, but now I am at the lead of trying to classify races such as blacks as a ghost population subspecies and part animal}.



-------------------------------------------



African Animals That Are Close to Extinction


30 April 2018


https://theculturetrip.com/africa/articles/african-animals-that-are-close-to-extinction/


-------------------------------------------- 

 

The Ring of Solomon and Surah 38:36-38

Jan 20, 2019

https://www.youtube.com/watch?v=cxheJas1hGM

 

--------------------------------------------


The time that Jesus called someone a dog

November 9, 2018

https://www.thebostonpilot.com/opinion/article.asp?ID=183681


-------------------------------


Jesus Calls a Canaanite Woman a Dog

https://www.tvcresources.net/resource-library/articles/jesus-calls-a-canaanite-woman-a-dog


-------------------------------


Dog-Headed Men From History are Real: Cynocephali Sightings

Mar 24, 2018

https://www.youtube.com/watch?v=G2oSbMFNDCw


-------------------------------


Do the Dog-Headed Men Have Souls? // Letter from 9th Century Monk // Primary Source

Oct 9, 2019

https://www.youtube.com/watch?v=_-5RZBKBl_A


--------------------------------


Three Historical Accounts of the Dog-Headed Men // Marco Polo, Ibn Battuta and Sir John Mandeville

Mar 13, 2020

https://www.youtube.com/watch?v=DMAC8Pc0QDA


--------------------------------


The Dog-Headed Men of India

Mar 15, 2020

https://www.youtube.com/watch?v=7D0qvnO3gls


------------------------------------------------


Hypertrichosis

https://en.wikipedia.org/wiki/Hypertrichosis


Hypertrichosis is an abnormal amount of hair growth over the body. The two distinct types of hypertrichosis are generalized hypertrichosis, which occurs over the entire body, and localized hypertrichosis, which is restricted to a certain area. Hypertrichosis can be either congenital (present at birth) or acquired later in life. The excess growth of hair occurs in areas of the skin with the exception of androgen-dependent hair of the pubic area, face, and axillary regions.

Several circus sideshow performers in the 19th and early 20th centuries, such as Julia Pastrana, had hypertrichosis. Many of them worked as freaks and were promoted as having distinct human and animal traits.









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Children in Spain develop ‘werewolf syndrome’ after taking contaminated medicine

27 Aug 2019


The 16 infants developed the highly rare condition, which causes excessive hair growth anywhere on a person’s body, after taking omeprazole for acid reflux and indigestion.








https://metro.co.uk/2019/08/27/children-spain-develop-werewolf-syndrome-taking-contaminated-medicine-10639945/



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{This article is a continuation of our following published articles in the following links}.



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 3/5/2019 - Race Dysgenics: Evolution, Dysgenic De-evolution, Eugenics & Genetic Modification - The History of the Lineage of Man  - https://racedysgenics.blogspot.com


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04/19/2018 The Dysgenics Investigation - Race, Science & the Human Genome Project - The Eugenics Investigation (Akoniti) - DysgenicsInvestigation.blogspot.com


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Race Virus 101 - The Eugenics Investigation ( The Dysgenics Investigation)

https://racevirus101.blogspot.com/

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8/15/2017 - Genetically Modified Vaccines Investigated - The Eugenics Investigation (MonsantoInvestigation.com) - GMOvaccinesinvestigated.blogspot.com

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Race Dysgenics Brazil | Eugenics in Brazil

https://eugenicsbrazil.blogspot.com

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Eugenics 101 (Dysgenics 101) - Genetics, Race, Science, Eugenics & Dysgenics 

October 15th, 2020

https://eugenics101.blogspot.com


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July 7th, 2017 - Genetically Modified Humans & Viruses - The Eugenics Investigation - GMOhumansandviruses.blogspot.com

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 4/4/2019 - The Rockefeller Dynasty Investigation 2020 - The Eugenics Investigation - https://rockefellerdynastyinvestigation.blogspot.com/


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Pollution Science 101 - China

https://pollutionscience101china.blogspot.com

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 Pollution Science 101 - Brazil - Emergency Report

https://pollutionscience101brazil.blogspot.com


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Pollution Science 101 - Mexico

https://pollutionscience101mexico.blogspot.com


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Pollution Science 101- Russia

https://pollutionscience101russia.blogspot.com

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Pollution Science 101 - India

https://pollutionscience101india.blogspot.com

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Pollution Science 101 - Cancer Investigated (California)

https://pollutionscience101cancerinvestigated.blogspot.com

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Pollution Science 101 - Israel

https://pollutionscience101israel.blogspot.com


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 King Solomon's Temple Investigation Marathon

https://solomonstempleinvestigation.blogspot.com/


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Pollution Science 101 - Texas

https://pollutionscience101texasvsbpoil.blogspot.com

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Pollution Science 101 - Solutions

https://pollutionscience101solutions.blogspot.com


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The DuPont Investigation

https://dupontinvestigation.blogspot.com


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Pollution Science 101 - Brazil - Emergency Report

https://pollutionscience101brazil.blogspot.com

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